A mouse model for distal renal tubular acidosis reveals a previously unrecognized role of the V-ATPase a4 subunit in the proximal tubule

EMBO Molecular Medicine

Volumn 4, Issue 10, 2012, Pages 1057-1071

  Hennings, J Christopher ^a   Picard, Nicolas ^b,c   Huebner, Antje K ^a   Stauber, Tobias ^d   Maier, Hannes ^e   Brown, Dennis ^f   Jentsch, Thomas J ^d   Vargas Poussou, Rosa ^g   Eladari, Dominique ^b,c,g   Hübner, Christian A ^a  

^a JENA UNIVERSITY HOSPITAL   (Germany)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c CENTRE DE RECHERCHE DES CORDELIERS   (France)

^d MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^e HANNOVER MEDICAL SCHOOL   (Germany)

^f HARVARD MEDICAL SCHOOL   (United States)

^g HÔPITAL EUROPÉEN GEORGES POMPIDOU   (France)

Author keywords

Deafness; Distal renal tubular acidosis; H+ ATPase; Kidney; Proteinuria

Indexed keywords

PENDRIN; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATASE; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATASE A4; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATASE B1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENDOLYMPH; ENDOLYMPHATIC SAC; HEARING IMPAIRMENT; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE ACIDOSIS; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PHOSPHATURIA; PRIORITY JOURNAL; PROTEINURIA; PROTON TRANSPORT;

ACIDOSIS, RENAL TUBULAR; ANIMALS; CHILD; CHILD, PRESCHOOL; DISEASE MODELS, ANIMAL; HUMANS; INFANT; KIDNEY TUBULES, PROXIMAL; MICE; MICE, KNOCKOUT; PROTEIN SUBUNITS; VACUOLAR PROTON-TRANSLOCATING ATPASES;

EID: 84867046146     PISSN: 17574676     EISSN: 17574684     Source Type: Journal    
DOI: 10.1002/emmm.201201527     Document Type: Article

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