Genetic Basis of Haloperidol Resistance in Saccharomyces cerevisiae Is Complex and Dose Dependent

PLoS Genetics

Volumn 10, Issue 12, 2014, Pages

  Wang, Xin ^a   Kruglyak, Leonid ^b,c  

^a PRINCETON UNIVERSITY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; HALOPERIDOL; OXYSTEROL BINDING PROTEIN; UNCLASSIFIED DRUG; ANTIFUNGAL AGENT; CARRIER PROTEIN; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; IRA2 PROTEIN, S CEREVISIAE; MKT1 PROTEIN, S CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEIN; SWH1 PROTEIN, S CEREVISIAE;

ARTICLE; CELL PH; CHROMOSOME 1; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG RESISTANCE; FUNGAL GENE; FUNGAL GENETICS; FUNGAL GENOME; FUNGAL STRAIN; GENE INTERACTION; GENE STRUCTURE; GENETIC POLYMORPHISM; GENETIC VARIABILITY; IRA2 GENE; LINKAGE ANALYSIS; MKT1 GENE; NONHUMAN; QUANTITATIVE TRAIT LOCUS; SACCHAROMYCES CEREVISIAE; SWH1 GENE; ANTIFUNGAL RESISTANCE; DOSE RESPONSE; DRUG EFFECTS; GENETICS; MICROBIAL SENSITIVITY TEST; PH;

SACCHAROMYCES CEREVISIAE;

ANTIFUNGAL AGENTS; CARRIER PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE, FUNGAL; GTPASE-ACTIVATING PROTEINS; HALOPERIDOL; HYDROGEN-ION CONCENTRATION; MICROBIAL SENSITIVITY TESTS; POLYMORPHISM, GENETIC; QUANTITATIVE TRAIT LOCI; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 84919608423     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1004894     Document Type: Article

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