메뉴 건너뛰기




Volumn 3, Issue 9, 2014, Pages 813-822

Embryonic development of the hypothalamic feeding circuitry: Transcriptional, nutritional, and hormonal influences

Author keywords

Basic helix loop helix; Developmental origins of health and disease; Hypothalamic neurogenesis; Leptin

Indexed keywords

LEPTIN;

EID: 84919486482     PISSN: None     EISSN: 22128778     Source Type: Journal    
DOI: 10.1016/j.molmet.2014.09.004     Document Type: Review
Times cited : (24)

References (97)
  • 1
    • 84884198186 scopus 로고    scopus 로고
    • Development of the hypothalamic melanocortin system
    • Coupe B., Bouret S.G. Development of the hypothalamic melanocortin system. Frontiers in Endocrinology 2013, 4:38.
    • (2013) Frontiers in Endocrinology , vol.4 , pp. 38
    • Coupe, B.1    Bouret, S.G.2
  • 3
    • 0015296012 scopus 로고
    • An autoradiographic study of the time of final division of neurons in rat hypothalamic nuclei
    • Ifft J. An autoradiographic study of the time of final division of neurons in rat hypothalamic nuclei. Journal of Comparative Neurology 1972, 144:193-204.
    • (1972) Journal of Comparative Neurology , vol.144 , pp. 193-204
    • Ifft, J.1
  • 4
    • 84864389230 scopus 로고    scopus 로고
    • Embryonic birthdate of hypothalamic leptin-activated neurons in mice
    • Ishii Y., Bouret S.G. Embryonic birthdate of hypothalamic leptin-activated neurons in mice. Endocrinology 2012, 153:3657-3667.
    • (2012) Endocrinology , vol.153 , pp. 3657-3667
    • Ishii, Y.1    Bouret, S.G.2
  • 5
    • 78149462716 scopus 로고    scopus 로고
    • Developmental genetics of vertebrate glial-cell specification
    • Rowitch D.H., Kriegstein A.R. Developmental genetics of vertebrate glial-cell specification. Nature 2010, 468:214-222.
    • (2010) Nature , vol.468 , pp. 214-222
    • Rowitch, D.H.1    Kriegstein, A.R.2
  • 6
    • 0018074265 scopus 로고
    • Development of the diencephalon in the rat. Correlation of the embryonic development of the hypothalamus with the time of origin of its neurons
    • Altman J., Bayer S. Development of the diencephalon in the rat. Correlation of the embryonic development of the hypothalamus with the time of origin of its neurons. Journal of Comparative Neurology 1978, 182:973-993.
    • (1978) Journal of Comparative Neurology , vol.182 , pp. 973-993
    • Altman, J.1    Bayer, S.2
  • 7
    • 77950547451 scopus 로고    scopus 로고
    • Pomc-expressing progenitors give rise to antagonistic populations in hypothalamic feeding circuits
    • Padilla S., Carmody J., Zeltser L. Pomc-expressing progenitors give rise to antagonistic populations in hypothalamic feeding circuits. Nature Medicine 2010, 16:403-405.
    • (2010) Nature Medicine , vol.16 , pp. 403-405
    • Padilla, S.1    Carmody, J.2    Zeltser, L.3
  • 8
    • 0034490095 scopus 로고    scopus 로고
    • Function of Rx, but not Pax6, is essential for the formation of retinal progenitor cells in mice
    • Zhang L., Mathers P., Jamrich M. Function of Rx, but not Pax6, is essential for the formation of retinal progenitor cells in mice. Genesis 2000, 28:135-142.
    • (2000) Genesis , vol.28 , pp. 135-142
    • Zhang, L.1    Mathers, P.2    Jamrich, M.3
  • 11
    • 0033746627 scopus 로고    scopus 로고
    • Dynamic expression of basic helix-loop-helix Olig family members: implication of Olig2 in neuron and oligodendrocyte differentiation and identification of a new member, Olig3
    • Takebayashi H., Yoshida S., Sugimori M., Kosako H., Kominami R., Nakafuku M., et al. Dynamic expression of basic helix-loop-helix Olig family members: implication of Olig2 in neuron and oligodendrocyte differentiation and identification of a new member, Olig3. Mechanisms of Development 2000, 99:143-148.
    • (2000) Mechanisms of Development , vol.99 , pp. 143-148
    • Takebayashi, H.1    Yoshida, S.2    Sugimori, M.3    Kosako, H.4    Kominami, R.5    Nakafuku, M.6
  • 12
    • 0033764232 scopus 로고    scopus 로고
    • Identification of a novel family of oligodendrocyte lineage-specific basic helix-loop-helix transcription factors
    • Zhou Q., Wang S., Anderson D.J. Identification of a novel family of oligodendrocyte lineage-specific basic helix-loop-helix transcription factors. Neuron 2000, 25:331-343.
    • (2000) Neuron , vol.25 , pp. 331-343
    • Zhou, Q.1    Wang, S.2    Anderson, D.J.3
  • 13
    • 0037023529 scopus 로고    scopus 로고
    • Common developmental requirement for Olig function indicates and motor neuron/oligodendrocyte connection
    • Lu Q., Sun T., Zhu Z., Ma N., Garcia M. Common developmental requirement for Olig function indicates and motor neuron/oligodendrocyte connection. Cell 2002, 109:75-86.
    • (2002) Cell , vol.109 , pp. 75-86
    • Lu, Q.1    Sun, T.2    Zhu, Z.3    Ma, N.4    Garcia, M.5
  • 15
    • 34447503745 scopus 로고    scopus 로고
    • BMPR1a signaling determines numbers of oligodendrocytes and calbindin-expressing interneurons in the cortex
    • Samanta J., Burke G.M., McGuire T., Pisarek A.J., Mukhopadhyay A., Mishina Y., et al. BMPR1a signaling determines numbers of oligodendrocytes and calbindin-expressing interneurons in the cortex. The Journal of Neuroscience 2007, 27:7397-7407.
    • (2007) The Journal of Neuroscience , vol.27 , pp. 7397-7407
    • Samanta, J.1    Burke, G.M.2    McGuire, T.3    Pisarek, A.J.4    Mukhopadhyay, A.5    Mishina, Y.6
  • 16
    • 0030268113 scopus 로고    scopus 로고
    • Neurogenins, a novel family of atonal-related bHLH transcription factors, are putative mammalian neuronal determination genes that reveal progenitor cell heterogeneity in the developing CNS and PNS
    • Sommer L., Ma Q., Anderson D.J. Neurogenins, a novel family of atonal-related bHLH transcription factors, are putative mammalian neuronal determination genes that reveal progenitor cell heterogeneity in the developing CNS and PNS. Molecular and Cellular Neuroscience 1996, 241:221-241.
    • (1996) Molecular and Cellular Neuroscience , vol.241 , pp. 221-241
    • Sommer, L.1    Ma, Q.2    Anderson, D.J.3
  • 17
    • 78650851195 scopus 로고    scopus 로고
    • Differential requirements for neurogenin 3 in the development of POMC and NPY neurons in the hypothalamus
    • Pelling M., Anthwal N., McNay D., Gradwohl G., Leiter A.B., Guillemot F., et al. Differential requirements for neurogenin 3 in the development of POMC and NPY neurons in the hypothalamus. Developmental Biology 2011, 349:406-416.
    • (2011) Developmental Biology , vol.349 , pp. 406-416
    • Pelling, M.1    Anthwal, N.2    McNay, D.3    Gradwohl, G.4    Leiter, A.B.5    Guillemot, F.6
  • 18
    • 77953380840 scopus 로고    scopus 로고
    • Expression of neuropeptide Y and agouti-related peptide in the hypothalamic arcuate nucleus of newborn neurogenin3 null mutant mice
    • Arai Y., Gradwohl G., Kameda Y. Expression of neuropeptide Y and agouti-related peptide in the hypothalamic arcuate nucleus of newborn neurogenin3 null mutant mice. Cell and Tissue Research 2010, 340:137-145.
    • (2010) Cell and Tissue Research , vol.340 , pp. 137-145
    • Arai, Y.1    Gradwohl, G.2    Kameda, Y.3
  • 19
    • 84883888324 scopus 로고    scopus 로고
    • Conditional deletion of Neurogenin3 using Nkx2.1Cre results in a mouse model for the central control of feeding, activity and obesity
    • Anthwal N., Pelling M., Claxton S., Mellitzer G., Collin C., Kessaris N., et al. Conditional deletion of Neurogenin3 using Nkx2.1Cre results in a mouse model for the central control of feeding, activity and obesity. Disease Models & Mechanisms 2013, 6:1133-1145.
    • (2013) Disease Models & Mechanisms , vol.6 , pp. 1133-1145
    • Anthwal, N.1    Pelling, M.2    Claxton, S.3    Mellitzer, G.4    Collin, C.5    Kessaris, N.6
  • 21
    • 0026824210 scopus 로고
    • NSCL-2: a basic domain helix-loop-helix gene expressed in early neurogenesis
    • Göbel V., Lipkowitz S., Kozak C., Kirsch I. NSCL-2: a basic domain helix-loop-helix gene expressed in early neurogenesis. Cell Growth & Differentiation 1992, 3:143-148.
    • (1992) Cell Growth & Differentiation , vol.3 , pp. 143-148
    • Göbel, V.1    Lipkowitz, S.2    Kozak, C.3    Kirsch, I.4
  • 22
    • 0030960861 scopus 로고    scopus 로고
    • Hypogonadism and obesity in mice with a targeted deletion of the Nhlh2 gene
    • Good D., Porter F., Mahon K., Parlow A., Westphal H., Kirsch I. Hypogonadism and obesity in mice with a targeted deletion of the Nhlh2 gene. Nature Genetics 1997, 15:397-401.
    • (1997) Nature Genetics , vol.15 , pp. 397-401
    • Good, D.1    Porter, F.2    Mahon, K.3    Parlow, A.4    Westphal, H.5    Kirsch, I.6
  • 25
    • 1642464993 scopus 로고    scopus 로고
    • Deletion of the Nhlh2 transcription factor decreases the levels of the anorexigenic peptides alpha melanocyte-stimulating hormone and thyrotropin-releasing hormone and implicates prohormone convertases I and II in obesity
    • Jing E., Nillni E.A., Sanchez V.C., Stuart R.C., Good D.J. Deletion of the Nhlh2 transcription factor decreases the levels of the anorexigenic peptides alpha melanocyte-stimulating hormone and thyrotropin-releasing hormone and implicates prohormone convertases I and II in obesity. Endocrinology 2004, 145:1503-1513.
    • (2004) Endocrinology , vol.145 , pp. 1503-1513
    • Jing, E.1    Nillni, E.A.2    Sanchez, V.C.3    Stuart, R.C.4    Good, D.J.5
  • 26
    • 44649197895 scopus 로고    scopus 로고
    • Nescient helix-loop-helix 2 interacts with signal transducer and activator of transcription 3 to regulate transcription of prohormone convertase 1/3
    • Fox D.L., Good D.J. Nescient helix-loop-helix 2 interacts with signal transducer and activator of transcription 3 to regulate transcription of prohormone convertase 1/3. Molecular Endocrinology 2008, 22:1438-1448.
    • (2008) Molecular Endocrinology , vol.22 , pp. 1438-1448
    • Fox, D.L.1    Good, D.J.2
  • 27
    • 84879164536 scopus 로고    scopus 로고
    • Loss of NSCL-2 in gonadotropin releasing hormone neurons leads to reduction of pro-opiomelanocortin neurons in specific hypothalamic nuclei and causes visceral obesity
    • Schmid T., Günther S., Mendler L., Braun T. Loss of NSCL-2 in gonadotropin releasing hormone neurons leads to reduction of pro-opiomelanocortin neurons in specific hypothalamic nuclei and causes visceral obesity. The Journal of Neuroscience 2013, 33:10459-10470.
    • (2013) The Journal of Neuroscience , vol.33 , pp. 10459-10470
    • Schmid, T.1    Günther, S.2    Mendler, L.3    Braun, T.4
  • 28
    • 33745654519 scopus 로고    scopus 로고
    • Mash1 is required for generic and subtype differentiation of hypothalamic neuroendocrine cells
    • McNay D.E.G., Pelling M., Claxton S., Guillemot F., Ang S.-L. Mash1 is required for generic and subtype differentiation of hypothalamic neuroendocrine cells. Molecular Endocrinology 2006, 20:1623-1632.
    • (2006) Molecular Endocrinology , vol.20 , pp. 1623-1632
    • McNay, D.E.G.1    Pelling, M.2    Claxton, S.3    Guillemot, F.4    Ang, S.-L.5
  • 29
    • 84881570967 scopus 로고    scopus 로고
    • Notch/Rbpjκ signaling regulates progenitor maintenance and differentiation of hypothalamic arcuate neurons
    • Aujla P.K., Naratadam G.T., Xu L., Raetzman L.T. Notch/Rbpjκ signaling regulates progenitor maintenance and differentiation of hypothalamic arcuate neurons. Development (Cambridge, England) 2013, 140:3511-3521.
    • (2013) Development (Cambridge, England) , vol.140 , pp. 3511-3521
    • Aujla, P.K.1    Naratadam, G.T.2    Xu, L.3    Raetzman, L.T.4
  • 30
    • 84881228970 scopus 로고    scopus 로고
    • Distinct glutamatergic and GABAergic subsets of hypothalamic pro-opiomelanocortin neurons revealed by in situ hybridization in male rats and mice
    • Wittmann G., Hrabovszky E., Lechan R.M. Distinct glutamatergic and GABAergic subsets of hypothalamic pro-opiomelanocortin neurons revealed by in situ hybridization in male rats and mice. The Journal of Comparative Neurology 2013, 521:3287-3302.
    • (2013) The Journal of Comparative Neurology , vol.521 , pp. 3287-3302
    • Wittmann, G.1    Hrabovszky, E.2    Lechan, R.M.3
  • 31
    • 0038747134 scopus 로고    scopus 로고
    • Role of signal transducer and activator of transcription 3 in regulation of hypothalamic proopiomelanocortin gene expression by leptin
    • Münzberg H., Huo L., Nillni E.A., Hollenberg A.N., Bjørbaek C. Role of signal transducer and activator of transcription 3 in regulation of hypothalamic proopiomelanocortin gene expression by leptin. Endocrinology 2003, 144:2121-2131.
    • (2003) Endocrinology , vol.144 , pp. 2121-2131
    • Münzberg, H.1    Huo, L.2    Nillni, E.A.3    Hollenberg, A.N.4    Bjørbaek, C.5
  • 33
    • 80053899725 scopus 로고    scopus 로고
    • Distinct hypothalamic neurons mediate estrogenic effects on energy homeostasis and reproduction
    • Xu Y., Nedungadi T.P., Zhu L., Sobhani N., Irani B.G., Davis K.E., et al. Distinct hypothalamic neurons mediate estrogenic effects on energy homeostasis and reproduction. Cell Metabolism 2011, 14:453-465.
    • (2011) Cell Metabolism , vol.14 , pp. 453-465
    • Xu, Y.1    Nedungadi, T.P.2    Zhu, L.3    Sobhani, N.4    Irani, B.G.5    Davis, K.E.6
  • 34
    • 79955934209 scopus 로고    scopus 로고
    • The estrogen receptor α colocalizes with proopiomelanocortin in hypothalamic neurons and binds to a conserved motif present in the neuron-specific enhancer nPE2
    • de Souza F.S.J., Nasif S., López-Leal R., Levi D.H., Low M.J., Rubinsten M. The estrogen receptor α colocalizes with proopiomelanocortin in hypothalamic neurons and binds to a conserved motif present in the neuron-specific enhancer nPE2. European Journal of Pharmacology 2011, 660:181-187.
    • (2011) European Journal of Pharmacology , vol.660 , pp. 181-187
    • de Souza, F.S.J.1    Nasif, S.2    López-Leal, R.3    Levi, D.H.4    Low, M.J.5    Rubinsten, M.6
  • 35
    • 79952003081 scopus 로고    scopus 로고
    • Respective contributions of maternal insulin resistance and diet to metabolic and hypothalamic phenotypes of progeny
    • Carmody J.S., Wan P., Accili D., Zeltser L.M., Leibel R.L. Respective contributions of maternal insulin resistance and diet to metabolic and hypothalamic phenotypes of progeny. Obesity 2011, 19:492-499.
    • (2011) Obesity , vol.19 , pp. 492-499
    • Carmody, J.S.1    Wan, P.2    Accili, D.3    Zeltser, L.M.4    Leibel, R.L.5
  • 36
    • 80054927541 scopus 로고    scopus 로고
    • Maternal diabetes compromises the organization of hypothalamic feeding circuits and impairs leptin sensitivity in offspring
    • Steculorum S.M., Bouret S.G. Maternal diabetes compromises the organization of hypothalamic feeding circuits and impairs leptin sensitivity in offspring. Endocrinology 2011, 152:4171-4179.
    • (2011) Endocrinology , vol.152 , pp. 4171-4179
    • Steculorum, S.M.1    Bouret, S.G.2
  • 37
    • 0028276035 scopus 로고
    • Developmental expression of mouse steroidogenic factor-1, an essential regulator of the steroid hydroxylases
    • Ikeda Y., Shen W.H., Ingraham H.A., Parker K.L. Developmental expression of mouse steroidogenic factor-1, an essential regulator of the steroid hydroxylases. Molecular Endocrinology 1994, 8:654-662.
    • (1994) Molecular Endocrinology , vol.8 , pp. 654-662
    • Ikeda, Y.1    Shen, W.H.2    Ingraham, H.A.3    Parker, K.L.4
  • 38
    • 0035079932 scopus 로고    scopus 로고
    • Comparative localization of Dax-1 and Ad4BP/SF-1 during development of the hypothalamic-pituitary-gonadal axis suggests their closely related and distinct functions
    • Ikeda Y., Takeda Y., Shikayama T., Mukai T., Hisano S., Morohashi K.I. Comparative localization of Dax-1 and Ad4BP/SF-1 during development of the hypothalamic-pituitary-gonadal axis suggests their closely related and distinct functions. Developmental Dynamics 2001, 220:363-376.
    • (2001) Developmental Dynamics , vol.220 , pp. 363-376
    • Ikeda, Y.1    Takeda, Y.2    Shikayama, T.3    Mukai, T.4    Hisano, S.5    Morohashi, K.I.6
  • 40
    • 0028959656 scopus 로고
    • The nuclear receptor steroidogenic factor 1 is essential for the formation of the ventromedial hypothalamic nucleus
    • Ikeda Y., Luo X., Abbud R., Nilson J.H., Parker K.L. The nuclear receptor steroidogenic factor 1 is essential for the formation of the ventromedial hypothalamic nucleus. Molecular Endocrinology 1995, 9:478-486.
    • (1995) Molecular Endocrinology , vol.9 , pp. 478-486
    • Ikeda, Y.1    Luo, X.2    Abbud, R.3    Nilson, J.H.4    Parker, K.L.5
  • 41
  • 43
    • 0037398246 scopus 로고    scopus 로고
    • Requirement of the orphan nuclear receptor SF-1 in terminal differentiation of ventromedial hypothalamic neurons
    • Tran P.V., Lee M.B., Marín O., Xu B., Jones K.R., Reichardt L.F., et al. Requirement of the orphan nuclear receptor SF-1 in terminal differentiation of ventromedial hypothalamic neurons. Molecular and Cellular Neuroscience 2003, 22:441-453.
    • (2003) Molecular and Cellular Neuroscience , vol.22 , pp. 441-453
    • Tran, P.V.1    Lee, M.B.2    Marín, O.3    Xu, B.4    Jones, K.R.5    Reichardt, L.F.6
  • 44
    • 3042793951 scopus 로고    scopus 로고
    • Loss of steroidogenic factor 1 alters cellular topography in the mouse ventromedial nucleus of the hypothalamus
    • Davis A.M., Seney M.L., Stallings N.R., Zhao L., Parker K.L., Tobet S.A. Loss of steroidogenic factor 1 alters cellular topography in the mouse ventromedial nucleus of the hypothalamus. Journal of Neurobiology 2004, 60:424-436.
    • (2004) Journal of Neurobiology , vol.60 , pp. 424-436
    • Davis, A.M.1    Seney, M.L.2    Stallings, N.R.3    Zhao, L.4    Parker, K.L.5    Tobet, S.A.6
  • 45
    • 37249019491 scopus 로고    scopus 로고
    • The neonatal ventromedial hypothalamus transcriptome reveals novel markers with spatially distinct patterning
    • Kurrasch D.M., Cheung C.C., Lee F.Y., Tran P.V., Hata K., Ingraham H.A. The neonatal ventromedial hypothalamus transcriptome reveals novel markers with spatially distinct patterning. The Journal of Neuroscience 2007, 27:13624-13634.
    • (2007) The Journal of Neuroscience , vol.27 , pp. 13624-13634
    • Kurrasch, D.M.1    Cheung, C.C.2    Lee, F.Y.3    Tran, P.V.4    Hata, K.5    Ingraham, H.A.6
  • 46
    • 0032702290 scopus 로고    scopus 로고
    • Progressive impairment of developing neuroendocrine cell lineages in the hypothalamus of mice lacking the Orthopedia gene
    • Acampora D. Progressive impairment of developing neuroendocrine cell lineages in the hypothalamus of mice lacking the Orthopedia gene. Genes & Development 1999, 2787-2800.
    • (1999) Genes & Development , pp. 2787-2800
    • Acampora, D.1
  • 47
    • 0034669078 scopus 로고    scopus 로고
    • The murine Otp homeobox gene plays an essential role in the specification of neuronal cell lineages in the developing hypothalamus
    • Wang W., Lufkin T. The murine Otp homeobox gene plays an essential role in the specification of neuronal cell lineages in the developing hypothalamus. Developmental Biology 2000, 227:432-449.
    • (2000) Developmental Biology , vol.227 , pp. 432-449
    • Wang, W.1    Lufkin, T.2
  • 48
    • 0032532480 scopus 로고    scopus 로고
    • Development of neuroendocrine lineages requires the bHLH-PAS transcription factor SIM1
    • Michaud J.L., Rosenquist T., May N.R., Fan C.-M. Development of neuroendocrine lineages requires the bHLH-PAS transcription factor SIM1. Genes & Development 1998, 12:3264-3275.
    • (1998) Genes & Development , vol.12 , pp. 3264-3275
    • Michaud, J.L.1    Rosenquist, T.2    May, N.R.3    Fan, C.-M.4
  • 49
  • 51
    • 0034016043 scopus 로고    scopus 로고
    • Profound obesity associated with a balanced translocation that disrupts the SIM1 gene
    • Holder J.L., Butte N.F., Zinn A.R. Profound obesity associated with a balanced translocation that disrupts the SIM1 gene. Human Molecular Genetics 2000, 9:101-108.
    • (2000) Human Molecular Genetics , vol.9 , pp. 101-108
    • Holder, J.L.1    Butte, N.F.2    Zinn, A.R.3
  • 52
  • 53
    • 0035393437 scopus 로고    scopus 로고
    • Sim1 haploinsufficiency causes hyperphagia, obesity and reduction of the paraventricular nucleus of the hypothalamus
    • Michaud J.L., Boucher F., Melnyk A., Gauthier F., Goshu E., Lévy E., et al. Sim1 haploinsufficiency causes hyperphagia, obesity and reduction of the paraventricular nucleus of the hypothalamus. Human Molecular Genetics 2001, 10:1465-1473.
    • (2001) Human Molecular Genetics , vol.10 , pp. 1465-1473
    • Michaud, J.L.1    Boucher, F.2    Melnyk, A.3    Gauthier, F.4    Goshu, E.5    Lévy, E.6
  • 54
    • 33748742610 scopus 로고    scopus 로고
    • Sim1 haploinsufficiency impairs melanocortin-mediated anorexia and activation of paraventricular nucleus neurons
    • Kublaoui B.M., Holder J.L., Gemelli T., Zinn A.R. Sim1 haploinsufficiency impairs melanocortin-mediated anorexia and activation of paraventricular nucleus neurons. Molecular Endocrinology (Baltimore, Md.) 2006, 20:2483-2492.
    • (2006) Molecular Endocrinology (Baltimore, Md.) , vol.20 , pp. 2483-2492
    • Kublaoui, B.M.1    Holder, J.L.2    Gemelli, T.3    Zinn, A.R.4
  • 56
    • 2942624067 scopus 로고    scopus 로고
    • Comparison of hypocretin/orexin and melanin-concentrating hormone neurons and axonal projections in the embryonic and postnatal rat brain
    • Steininger T.L., Kilduff T.S., Behan M., Benca R.M., Landry C.F. Comparison of hypocretin/orexin and melanin-concentrating hormone neurons and axonal projections in the embryonic and postnatal rat brain. Journal of Chemical Neuroanatomy 2004, 27:165-181.
    • (2004) Journal of Chemical Neuroanatomy , vol.27 , pp. 165-181
    • Steininger, T.L.1    Kilduff, T.S.2    Behan, M.3    Benca, R.M.4    Landry, C.F.5
  • 57
    • 83455245899 scopus 로고    scopus 로고
    • Development of posterior hypothalamic neurons enlightens a switch in the prosencephalic basic plan
    • Croizier S., Amiot C., Chen X., Presse F., Nahon J.-L., Wu J.Y., et al. Development of posterior hypothalamic neurons enlightens a switch in the prosencephalic basic plan. PLoS One 2011, 6:e28574.
    • (2011) PLoS One , vol.6 , pp. e28574
    • Croizier, S.1    Amiot, C.2    Chen, X.3    Presse, F.4    Nahon, J.-L.5    Wu, J.Y.6
  • 58
    • 0035000913 scopus 로고    scopus 로고
    • Ontogenetic development of the diencephalic MCH neurons: a hypothalamic 'MCH area' hypothesis
    • Brischoux F., Fellmann D., Risold P.Y. Ontogenetic development of the diencephalic MCH neurons: a hypothalamic 'MCH area' hypothesis. The European Journal of Neuroscience 2001, 13:1733-1744.
    • (2001) The European Journal of Neuroscience , vol.13 , pp. 1733-1744
    • Brischoux, F.1    Fellmann, D.2    Risold, P.Y.3
  • 60
    • 77952085931 scopus 로고    scopus 로고
    • Moderate caloric restriction during gestation results in lower arcuate nucleus NPY- and αMSH-neurons and impairs hypothalamic response to fed/fasting conditions in weaned rats
    • Garcia A., Palou M., Priego T. Moderate caloric restriction during gestation results in lower arcuate nucleus NPY- and αMSH-neurons and impairs hypothalamic response to fed/fasting conditions in weaned rats. Diabetes, Obesity and Metabolism 2010, 403-413.
    • (2010) Diabetes, Obesity and Metabolism , pp. 403-413
    • Garcia, A.1    Palou, M.2    Priego, T.3
  • 61
    • 34247337735 scopus 로고    scopus 로고
    • Prenatal influences on susceptibility to diet-induced obesity are mediated by altered neuroendocrine gene expression
    • Ikenasio-Thorpe B.A., Breier B.H., Vickers M.H., Fraser M. Prenatal influences on susceptibility to diet-induced obesity are mediated by altered neuroendocrine gene expression. The Journal of Endocrinology 2007, 193:31-37.
    • (2007) The Journal of Endocrinology , vol.193 , pp. 31-37
    • Ikenasio-Thorpe, B.A.1    Breier, B.H.2    Vickers, M.H.3    Fraser, M.4
  • 62
    • 79951953438 scopus 로고    scopus 로고
    • Hypothalamic neurosphere progenitor cells in low birth-weight rat newborns: neurotrophic effects of leptin and insulin
    • Desai M., Li T., Ross M.G. Hypothalamic neurosphere progenitor cells in low birth-weight rat newborns: neurotrophic effects of leptin and insulin. Brain Research 2011, 1378:29-42.
    • (2011) Brain Research , vol.1378 , pp. 29-42
    • Desai, M.1    Li, T.2    Ross, M.G.3
  • 63
    • 57749203609 scopus 로고    scopus 로고
    • Perinatal undernutrition modifies cell proliferation and brain-derived neurotrophic factor levels during critical time-windows for hypothalamic and hippocampal development in the male rat
    • Coupé B., Dutriez-Casteloot I., Breton C., Lefèvre F., Mairesse J., Dickes-Coopman A., et al. Perinatal undernutrition modifies cell proliferation and brain-derived neurotrophic factor levels during critical time-windows for hypothalamic and hippocampal development in the male rat. Journal of Neuroendocrinology 2009, 21:40-48.
    • (2009) Journal of Neuroendocrinology , vol.21 , pp. 40-48
    • Coupé, B.1    Dutriez-Casteloot, I.2    Breton, C.3    Lefèvre, F.4    Mairesse, J.5    Dickes-Coopman, A.6
  • 64
    • 67650901466 scopus 로고    scopus 로고
    • Hypothalamic neuroendocrine circuitry is programmed by maternal obesity: interaction with postnatal nutritional environment
    • Chen H., Simar D., Morris M.J. Hypothalamic neuroendocrine circuitry is programmed by maternal obesity: interaction with postnatal nutritional environment. PLoS One 2009, 4:e6259.
    • (2009) PLoS One , vol.4 , pp. e6259
    • Chen, H.1    Simar, D.2    Morris, M.J.3
  • 65
    • 58149490989 scopus 로고    scopus 로고
    • Established maternal obesity in the rat reprograms hypothalamic appetite regulators and leptin signaling at birth
    • Morris M.J., Chen H. Established maternal obesity in the rat reprograms hypothalamic appetite regulators and leptin signaling at birth. International Journal of Obesity (2005) 2009, 33:115-122.
    • (2009) International Journal of Obesity (2005) , vol.33 , pp. 115-122
    • Morris, M.J.1    Chen, H.2
  • 66
    • 58149336861 scopus 로고    scopus 로고
    • Maternal high-fat diet and fetal programming: increased proliferation of hypothalamic peptide-producing neurons that increase risk for overeating and obesity
    • Chang G.-Q., Gaysinskaya V., Karatayev O., Leibowitz S.F. Maternal high-fat diet and fetal programming: increased proliferation of hypothalamic peptide-producing neurons that increase risk for overeating and obesity. The Journal of Neuroscience 2008, 28:12107-12119.
    • (2008) The Journal of Neuroscience , vol.28 , pp. 12107-12119
    • Chang, G.-Q.1    Gaysinskaya, V.2    Karatayev, O.3    Leibowitz, S.F.4
  • 67
    • 75749097419 scopus 로고    scopus 로고
    • Glucose metabolic and gluconeogenic pathways disturbance in the intrauterine growth restricted adult male rats
    • Liu X.-m., Kong J., Song W.-w., Lu Y. Glucose metabolic and gluconeogenic pathways disturbance in the intrauterine growth restricted adult male rats. Chinese Medical Sciences Journal 2009, 24:208-212.
    • (2009) Chinese Medical Sciences Journal , vol.24 , pp. 208-212
    • Liu, X.-M.1    Kong, J.2    Song, W.-W.3    Lu, Y.4
  • 68
    • 78149440714 scopus 로고    scopus 로고
    • Nutritional programming in the rat is linked to long-lasting changes in nutrient sensing and energy homeostasis in the hypothalamus
    • Orozco-Solís R., Matos R.J.B., Guzmán-Quevedo O., Lopes de Souza S., Bihouée A., Houlgatte R., et al. Nutritional programming in the rat is linked to long-lasting changes in nutrient sensing and energy homeostasis in the hypothalamus. PLoS One 2010, 5:e13537.
    • (2010) PLoS One , vol.5 , pp. e13537
    • Orozco-Solís, R.1    Matos, R.J.B.2    Guzmán-Quevedo, O.3    Lopes de Souza, S.4    Bihouée, A.5    Houlgatte, R.6
  • 69
    • 0033802933 scopus 로고    scopus 로고
    • Hypothalamic nuclei are malformed in weanling offspring of low protein malnourished rat dams
    • Plagemann A., Harder T., Rake A., Melchior K., Rohde W., Dörner G. Hypothalamic nuclei are malformed in weanling offspring of low protein malnourished rat dams. The Journal of Nutrition 2000, 130:2582-2589.
    • (2000) The Journal of Nutrition , vol.130 , pp. 2582-2589
    • Plagemann, A.1    Harder, T.2    Rake, A.3    Melchior, K.4    Rohde, W.5    Dörner, G.6
  • 70
    • 1842536210 scopus 로고    scopus 로고
    • Trophic action of leptin on hypothalamic neurons that regulate feeding
    • Bouret S.G., Draper S.J., Simerly R.B. Trophic action of leptin on hypothalamic neurons that regulate feeding. Science 2004, 304:108-110.
    • (2004) Science , vol.304 , pp. 108-110
    • Bouret, S.G.1    Draper, S.J.2    Simerly, R.B.3
  • 71
    • 0038649327 scopus 로고    scopus 로고
    • Leptin distribution and metabolism in the pregnant rat: transplacental leptin passage increases in late gestation but is reduced by excess glucocorticoids
    • Smith J.T. Leptin distribution and metabolism in the pregnant rat: transplacental leptin passage increases in late gestation but is reduced by excess glucocorticoids. Endocrinology 2003, 144:3024-3030.
    • (2003) Endocrinology , vol.144 , pp. 3024-3030
    • Smith, J.T.1
  • 74
    • 0034705646 scopus 로고    scopus 로고
    • Expression of the long form of leptin receptor (Ob-Rb) mRNA in the brain of mouse embryos and newborn mice
    • Udagawa J., Hatta T., Naora H., Otani H. Expression of the long form of leptin receptor (Ob-Rb) mRNA in the brain of mouse embryos and newborn mice. Brain Research 2000, 868:251-258.
    • (2000) Brain Research , vol.868 , pp. 251-258
    • Udagawa, J.1    Hatta, T.2    Naora, H.3    Otani, H.4
  • 78
    • 0018409557 scopus 로고
    • Altered neuroanatomical organization in the central nervous system of the genetically obese (ob/ob) mouse
    • Bereiter D., Jeanrenaud B. Altered neuroanatomical organization in the central nervous system of the genetically obese (ob/ob) mouse. Brain Research 1979, 165:249-260.
    • (1979) Brain Research , vol.165 , pp. 249-260
    • Bereiter, D.1    Jeanrenaud, B.2
  • 79
    • 30944444381 scopus 로고    scopus 로고
    • The role of leptin in the development of the cerebral cortex in mouse embryos
    • Udagawa J., Hashimoto R., Suzuki H., Hatta T., Sotomaru Y., Hioki K., et al. The role of leptin in the development of the cerebral cortex in mouse embryos. Endocrinology 2006, 147:647-658.
    • (2006) Endocrinology , vol.147 , pp. 647-658
    • Udagawa, J.1    Hashimoto, R.2    Suzuki, H.3    Hatta, T.4    Sotomaru, Y.5    Hioki, K.6
  • 80
    • 0024437541 scopus 로고
    • Morphometric analysis of obesity (ob/ob)- and diabetes (db/db)-associated hypothalamic neuronal degeneration in C57BL/KsJ mice
    • Garris D.R. Morphometric analysis of obesity (ob/ob)- and diabetes (db/db)-associated hypothalamic neuronal degeneration in C57BL/KsJ mice. Brain Research 1989, 501:162-170.
    • (1989) Brain Research , vol.501 , pp. 162-170
    • Garris, D.R.1
  • 81
    • 79959786959 scopus 로고    scopus 로고
    • Fetal hypothalamic neuroprogenitor cell culture: preferential differentiation paths induced by leptin and insulin
    • Desai M., Li T., Ross M.G. Fetal hypothalamic neuroprogenitor cell culture: preferential differentiation paths induced by leptin and insulin. Endocrinology 2011, 152:3192-3201.
    • (2011) Endocrinology , vol.152 , pp. 3192-3201
    • Desai, M.1    Li, T.2    Ross, M.G.3
  • 83
    • 0038457891 scopus 로고    scopus 로고
    • BMPs signal alternately through a SMAD or FRAP-STAT pathway to regulate fate choice in CNS stem cells
    • Rajan P., Panchision D.M., Newell L.F., McKay R.D.G. BMPs signal alternately through a SMAD or FRAP-STAT pathway to regulate fate choice in CNS stem cells. The Journal of Cell Biology 2003, 161:911-921.
    • (2003) The Journal of Cell Biology , vol.161 , pp. 911-921
    • Rajan, P.1    Panchision, D.M.2    Newell, L.F.3    McKay, R.D.G.4
  • 84
  • 86
    • 84863051235 scopus 로고    scopus 로고
    • Distinct roles for specific leptin receptor signals in the development of hypothalamic feeding circuits
    • Bouret S.G., Bates S.H., Chen S., Myers M.G., Simerly R.B. Distinct roles for specific leptin receptor signals in the development of hypothalamic feeding circuits. The Journal of Neuroscience 2012, 32:1244-1252.
    • (2012) The Journal of Neuroscience , vol.32 , pp. 1244-1252
    • Bouret, S.G.1    Bates, S.H.2    Chen, S.3    Myers, M.G.4    Simerly, R.B.5
  • 87
    • 0035102275 scopus 로고    scopus 로고
    • The nodal pathway acts upstream of hedgehog signaling to specify ventral telencephalic identity
    • Rohr K.B., Barth K.A., Varga Z.M., Wilson S.W. The nodal pathway acts upstream of hedgehog signaling to specify ventral telencephalic identity. Neuron 2001, 29:341-351.
    • (2001) Neuron , vol.29 , pp. 341-351
    • Rohr, K.B.1    Barth, K.A.2    Varga, Z.M.3    Wilson, S.W.4
  • 88
    • 0033679003 scopus 로고    scopus 로고
    • The role of cholesterol in Shh signaling and teratogen-induced holoprosencephaly
    • Incardona J.P., Roelink H. The role of cholesterol in Shh signaling and teratogen-induced holoprosencephaly. Cellular and Molecular Life Sciences 2000, 57:1709-1719.
    • (2000) Cellular and Molecular Life Sciences , vol.57 , pp. 1709-1719
    • Incardona, J.P.1    Roelink, H.2
  • 89
    • 0031805560 scopus 로고    scopus 로고
    • Demarcation of ventral territories by the homeobox gene NKX2.1 during early chick development
    • Pera E.M., Kessel M. Demarcation of ventral territories by the homeobox gene NKX2.1 during early chick development. Development Genes and Evolution 1998, 208:168-171.
    • (1998) Development Genes and Evolution , vol.208 , pp. 168-171
    • Pera, E.M.1    Kessel, M.2
  • 90
    • 79952372491 scopus 로고    scopus 로고
    • Thyroid transcription factor-1 regulates feeding behavior via melanocortin pathway in the hypothalamus
    • Kim J.G., Park B.S., Yun C.H., Kim H.J., Kang S.S., D'Elia A.V., et al. Thyroid transcription factor-1 regulates feeding behavior via melanocortin pathway in the hypothalamus. Diabetes 2011, 60:710-719.
    • (2011) Diabetes , vol.60 , pp. 710-719
    • Kim, J.G.1    Park, B.S.2    Yun, C.H.3    Kim, H.J.4    Kang, S.S.5    D'Elia, A.V.6
  • 92
    • 0345096617 scopus 로고    scopus 로고
    • Bsx, an evolutionary conserved Brain Specific homeoboX gene expressed in the septum, epiphysis, mammillary bodies and arcuate nucleus
    • Cremona M., Colombo E., Andreazzoli M., Cossu G., Broccoli V. Bsx, an evolutionary conserved Brain Specific homeoboX gene expressed in the septum, epiphysis, mammillary bodies and arcuate nucleus. Gene Expression Patterns 2004, 4:47-51.
    • (2004) Gene Expression Patterns , vol.4 , pp. 47-51
    • Cremona, M.1    Colombo, E.2    Andreazzoli, M.3    Cossu, G.4    Broccoli, V.5
  • 93
    • 44249124216 scopus 로고    scopus 로고
    • Bsx, a novel hypothalamic factor linking feeding with locomotor activity, is regulated by energy availability
    • Nogueiras R., Lopez M., Lage R., Perez-Tilve D., Pfluger P., Mendieta-Zeron H., et al. Bsx, a novel hypothalamic factor linking feeding with locomotor activity, is regulated by energy availability. Endocrinology 2008, 149:3009-3015.
    • (2008) Endocrinology , vol.149 , pp. 3009-3015
    • Nogueiras, R.1    Lopez, M.2    Lage, R.3    Perez-Tilve, D.4    Pfluger, P.5    Mendieta-Zeron, H.6
  • 94
    • 34249707945 scopus 로고    scopus 로고
    • Arole for brain-specific homeobox factor Bsx in the control of hyperphagia and locomotory behavior
    • Sakkou M., Wiedmer P., Anlag K., Hamm A., Seuntjens E., Ettwiller L., et al. Arole for brain-specific homeobox factor Bsx in the control of hyperphagia and locomotory behavior. Cell Metabolism 2007, 5:450-463.
    • (2007) Cell Metabolism , vol.5 , pp. 450-463
    • Sakkou, M.1    Wiedmer, P.2    Anlag, K.3    Hamm, A.4    Seuntjens, E.5    Ettwiller, L.6
  • 95
    • 34547470482 scopus 로고    scopus 로고
    • Expression of the hypothalamic transcription factor Nhlh2 is dependent on energy availability
    • Vella K.R., Burnside A.S., Brennan K.M., Good D.J. Expression of the hypothalamic transcription factor Nhlh2 is dependent on energy availability. Journal of Neuroendocrinology 2007, 19:499-510.
    • (2007) Journal of Neuroendocrinology , vol.19 , pp. 499-510
    • Vella, K.R.1    Burnside, A.S.2    Brennan, K.M.3    Good, D.J.4
  • 96
    • 84896696218 scopus 로고    scopus 로고
    • Leptin signaling regulates hypothalamic expression of nescient helix-loop-helix 2 (Nhlh2) through signal transducer and activator 3 (Stat3)
    • Al Rayyan N., Zhang J., Burnside A.S., Good D.J. Leptin signaling regulates hypothalamic expression of nescient helix-loop-helix 2 (Nhlh2) through signal transducer and activator 3 (Stat3). Molecular and Cellular Endocrinology 2014, 384:134-142.
    • (2014) Molecular and Cellular Endocrinology , vol.384 , pp. 134-142
    • Al Rayyan, N.1    Zhang, J.2    Burnside, A.S.3    Good, D.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.