The selective antagonism of P2X7and P2Y1receptors prevents synaptic failure and affects cell proliferation induced by oxygen and glucose deprivation in rat dentate gyrus

PLoS ONE

Volumn 9, Issue 12, 2014, Pages

  Maraula, Giovanna ^a   Lana, Daniele ^a   Coppi, Elisabetta ^a   Gentile, Francesca ^a   Mello, Tommaso ^b   Melani, Alessia ^a   Galli, Andrea ^b   Giovannini, Maria Grazia ^a   Pedata, Felicita ^a   Pugliese, Anna Maria Aria ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

^b UNIVERSITY OF FLORENCE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

2' DEOXY 6 N METHYLADENOSINE 3',5' BISPHOSPHATE; BRILLIANT BLUE G; BROXURIDINE; DOUBLECORTIN; GLUCOSE; OXYGEN; PURINERGIC P2 RECEPTOR ANTAGONIST; PURINERGIC P2X7 RECEPTOR; PURINERGIC P2Y1 RECEPTOR; UNCLASSIFIED DRUG; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; COOMASSIE BRILLIANT BLUE; FUCHSINE; N(6)-METHYL-2'-DEOXYADENOSINE 3',5'-DIPHOSPHATE; PURINERGIC P2X RECEPTOR ANTAGONIST; PURINERGIC P2Y RECEPTOR ANTAGONIST;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL MATURATION; CELL MEMBRANE DEPOLARIZATION; CELL PROLIFERATION; CONTROLLED STUDY; DENTATE GYRUS; GLUCOSE INTAKE; GRANULE CELL; HIPPOCAMPUS; IMMUNOFLUORESCENCE TEST; IN VITRO STUDY; IN VIVO STUDY; MALE; NEUROTRANSMISSION; NONHUMAN; POSTSYNAPTIC POTENTIAL; RAT; TISSUE OXYGENATION; ANALOGS AND DERIVATIVES; ANIMAL; BRAIN ISCHEMIA; CELL CULTURE; CELL HYPOXIA; CHEMICALLY INDUCED; DEFICIENCY; DRUG EFFECTS; METABOLISM; PATHOPHYSIOLOGY; SYNAPTIC TRANSMISSION; WISTAR RAT;

RATTUS;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ANIMALS; BRAIN ISCHEMIA; CELL HYPOXIA; CELL PROLIFERATION; CELLS, CULTURED; DENTATE GYRUS; GLUCOSE; MALE; PURINERGIC P2X RECEPTOR ANTAGONISTS; PURINERGIC P2Y RECEPTOR ANTAGONISTS; RATS; RATS, WISTAR; RECEPTORS, PURINERGIC P2X7; RECEPTORS, PURINERGIC P2Y1; ROSANILINE DYES; SYNAPTIC TRANSMISSION;

EID: 84919471682     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0115273     Document Type: Article

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