Doublecortin supports the development of dendritic arbors in primary hippocampal neurons

Developmental Neuroscience

Volumn 30, Issue 1-3, 2007, Pages 187-199

  Cohen, Dror ^a   Segal, Menahem ^a   Reiner, Orly ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

Dendrite morphology; Doublecortin; Neuronal maturation

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; DOUBLECORTIN; GREEN FLUORESCENT PROTEIN;

ANALYTIC METHOD; ANIMAL CELL; ARTICLE; CELL CULTURE; CELL MATURATION; CELL MIGRATION; CONTROLLED STUDY; DENDRITE; DOUBLECORTIN GENE; GENE; HIPPOCAMPUS; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RNA INTERFERENCE;

ANIMALS; ANIMALS, NEWBORN; CELL DIFFERENTIATION; CELL SHAPE; CELLS, CULTURED; DENDRITES; DOWN-REGULATION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HIPPOCAMPUS; MICROTUBULE-ASSOCIATED PROTEINS; NEURAL PATHWAYS; NEURONS; NEUROPEPTIDES; RATS; RECEPTORS, GABA-A; RNA INTERFERENCE; SYNAPSES; SYNAPTIC TRANSMISSION;

EID: 37149036131     PISSN: 03785866     EISSN: None     Source Type: Journal    
DOI: 10.1159/000109862     Document Type: Article

References (36)

1. Gleeson JG, Allen KM, Fox JW, Lamperti ED, Berkovic S, Scheffer I, Cooper EC, Dobyns WB, Minnerath SR, Ross ME, Walsh CA: Doublecortin, a brain-specific gene mutated in human X-linked lissencephaly and double cortex syndrome, encodes a putative signaling protein. Cell 1998;92:63-72.
2. Des Portes V, Pinard JM, Billuart P, Vinet MC, Koulakoff A, Carrie A, Gelot A, Dupuis E, Motte J, Berwald-Netter Y, Catala M, Kahn A, Beldjord C, Chelly J: A novel CNS gene required for neuronal migration and involved in X-linked subcortical laminar heterotopia and lissencephaly syndrome. Cell 1998;92:51-61.
3. Dobyns WB, Andermann E, Andermann F, Czapansky-Beilman D, Dubeau F, Dulac O, Guerrini R, Hirsch B, Ledbetter DH, Lee NS, Motte J, Pinard JM, Radtke RA, Ross ME, Tampieri D, Walsh CA, Truwit CL: X-linked malformations of neuronal migration. Neurology 1996;47:331-339.
4. Corbo JC, Deuel TA, Long JM, LaPorte P, Tsai E, Wynshaw-Boris A, Walsh CA: Doublecortin is required in mice for lamination of the hippocampus but not the neocortex. J Neurosci 2002;22:7548-7557.
5. Bai J, Ramos RL, Ackman JB, Thomas AM, Lee RV, LoTurco JJ: RNAi reveals doublecortin is required for radial migration in rat neocortex. Nat Neurosci 2003;6:1277-1283.
6. Koizumi H, Higginbotham H, Poon T, Tanaka T, Brinkman BC, Gleeson JG: Doublecortin maintains bipolar shape and nuclear translocation during migration in the adult forebrain. Nat Neurosci 2006;9:779-786.
7. Kappeler C, Saillour Y, Baudoin JP, Tuy FP, Alvarez C, Houbron C, Gaspar P, Hamard G, Chelly J, Metin C, Francis F: Branching and nucleokinesis defects in migrating interneurons derived from doublecortin knockout mice. Hum Mol Genet 2006;15:1387-1400.
8. Deuel TA, Liu JS, Corbo JC, Yoo SY, Rorke-Adams LB, Walsh CA: Genetic interactions between doublecortin and doublecortin-like kinase in neuronal migration and axon outgrowth. Neuron 2006;49:41-53.
9. Koizumi H, Tanaka T, Gleeson JG: Doublecortin-like kinase functions with doublecortin to mediate fiber tract decussation and neuronal migration. Neuron 2006;49:55-66.
10. Friocourt G, Koulakoff A, Chafey P, Boucher D, Fauchereau F, Chelly J, Francis F: Doublecortin functions at the extremities of growing neuronal processes. Cereb Cortex 2003;13:620-626.
11. Schaar BT, Kinoshita K, McConnell SK: Doublecortin microtubule affinity is regulated by a balance of kinase and phosphatase activity at the leading edge of migrating neurons. Neuron 2004;41:203-213.
12. Tanaka T, Serneo FF, Higgins C, Gambello MJ, Wynshaw-Boris A, Gleeson JG: Lis1 and doublecortin function with dynein to mediate coupling of the nucleus to the centrosome in neuronal migration. J Cell Biol 2004;165:709-721.
13. Francis F, Koulakoff A, Boucher D, Chafey P, Schaar B, Vinet MC, Friocourt G, McDonnell N, Reiner O, Kahn A, McConnell SK, Berwald-Netter Y, Denoulet P, Chelly J: Doublecortin is a developmentally regulated, microtubule-associated protein expressed in migrating and differentiating neurons. Neuron 1999;23:247-256.
14. Brown JP, Couillard-Despres S, Cooper-Kuhn CM, Winkler J, Aigner L, Kuhn HG: Transient expression of doublecortin during adult neurogenesis. J Comp Neurol 2003;467:1-10.
15. Rao MS, Shetty AK: Efficacy of doublecortin as a marker to analyse the absolute number and dendritic growth of newly generated neurons in the adult dentate gyrus. Eur J Neurosci 2004;19:234-246.
16. Lambert de Rouvroit C, Goffinet AM: Neuronal migration. Mech Dev 2001;105:47-56.
17. Hatanaka Y, Murakami F: In vitro analysis of the origin, migratory behavior, and maturation of cortical pyramidal cells. J Comp Neurol 2002;454:1-14.
18. Horesh D, Sapir T, Francis F, Wolf SG, Caspi M, Elbaum M, Chelly J, Reiner O: Doublecortin, a stabilizer of microtubules. Hum Mol Genet 1999;8:1599-1610.
19. Gleeson JG, Lin PT, Flanagan LA, Walsh CA: Doublecortin is a microtubule-associated protein and is expressed widely by migrating neurons. Neuron 1999;23:257-271.
20. Moores CA, Perderiset M, Kappeler C, Kain S, Drummond D, Perkins SJ, Chelly J, Cross R, Houdusse A, Francis F: Distinct roles of doublecortin modulating the microtubule cytoskeleton. EMBO J 2006;25:4448-4457.
21. Moores CA, Perderiset M, Francis F, Chelly J, Houdusse A, Milligan RA: Mechanism of microtubule stabilization by doublecortin. Mol Cell 2004;14:833-839.
22. McAllister AK: Cellular and molecular mechanisms of dendrite growth. Cereb Cortex 2000;10:963-973.
23. Frotscher M, Drakew A, Heimrich B: Role of afferent innervation and neuronal activity in dendritic development and spine maturation of fascia dentata granule cells. Cereb Cortex 2000;10:946-951.
24. Tailby C, Wright LL, Metha AB, Calford MB: Activity-dependent maintenance and growth of dendrites in adult cortex. Proc Natl Acad Sci USA 2005;102:4631-4636.
25. Nuijtinck RR, Baker RE, Ter Gast E, Struik ML, Mud MT: Glutamate-dependent dendritic outgrowth in developing neuronal networks of rat hippocampal cells in vitro. Int J Dev Neurosci 1997;15:55-60.
26. Ben-Ari Y, Cherubini E, Corradetti R, Gaiarsa JL: Giant synaptic potentials in immature rat CA3 hippocampal neurones. J Physiol 1989;416:303-325.
27. Barbin G, Pollard H, Gaiarsa JL, Ben-Ari Y: Involvement of GABAA receptors in the outgrowth of cultured hippocampal neurons. Neurosci Lett 1993;152:150-154.
28. Goldin M, Segal M, Avignone E: Functional plasticity triggers formation and pruning of dendritic spines in cultured hippocampal networks. J Neurosci 2001;21:186-193.
29. Papa M, Bundman MC, Greenberger V, Segal M: Morphological analysis of dendritic spine development in primary cultures of hippocampal neurons. J Neurosci 1995;15:1-11.
30. Shmueli O, Gdalyahu A, Sorokina K, Nevo E, Avivi A, Reiner O: DCX in PC12 cells: CREB-mediated transcription and neurite outgrowth. Hum Mol Genet 2001;10:1061-1070.
31. Tsukada M, Prokscha A, Eichele G: Neurabin II mediates doublecortin-dephosphorylation on actin filaments. Biochem Biophys Res Commun 2006;343:839-847.
32. Tsukada M, Prokscha A, Ungewickell E, Eichele G: Doublecortin association with actin filaments is regulated by neurabin II. J Biol Chem 2005;280:11361-11368.
33. Gleeson JG, Minnerath SR, Fox JW, Allen KM, Luo RF, Hong SE, Berg MJ, Kuzniecky R, Reitnauer PJ, Borgatti R, Mira AP, Guerrini R, Holmes GL, Rooney CM, Berkovic S, Scheffer I, Cooper EC, Ricci S, Cusmai R, Crawford TO, Leroy R, Andermann E, Wheless JW, Dobyns WB, Walsh CA, et al: Characterization of mutations in the gene doublecortin in patients with double cortex syndrome. Ann Neurol 1999;45:146-153.
34. Sapir T, Horesh D, Caspi M, Atlas R, Burgess HA, Wolf SG, Francis F, Chelly J, Elbaum M, Pietrokovski S, Reiner O: Doublecortin mutations cluster in evolutionarily conserved functional domains. Hum Mol Genet 2000;9:703-712.
35. Taylor KR, Holzer AK, Bazan JF, Walsh CA, Gleeson JG: Patient mutations in doublecortin define a repeated tubulin-binding domain. J Biol Chem 2000;275:34442-34450.
36. Reiner O, Coquelle FM, Peter B, Levy T, Kaplan A, Sapir T, Orr I, Barkai N, Eichele G, Bergmann S: The evolving doublecortin (DCX) superfamily. BMC Genomics 2006;7:188.