Key hub and bottleneck genes differentiate the macrophage response to virulent and attenuated Mycobacterium bovis

Frontiers in Immunology

Volumn 5, Issue AUG, 2014, Pages

  Killick, Kate E ^a   Magee, David A ^a   Park, Stephen D E ^a,b   Taraktsoglou, Maria ^a,c   Browne, John A ^a   Conlon, Kevin M ^a,d   Nalpas, Nicolas C ^a   Gormley, Eamonn ^a   Gordon, Stephen V ^a   MacHugh, David E ^a   Hokamp, Karsten ^e  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

^b IDENTIGEN LTD   (Ireland)

^c HEALTH AND SAFETY EXECUTIVE   (United Kingdom)

^d SCIENCE FOUNDATION IRELAND   (Ireland)

^e TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

BCG; Cattle; Gene interaction network; Macrophage; Mycobacterium bovis; Network; Tuberculosis

Indexed keywords

ANIMAL CELL; ARTICLE; CELL DEATH; EGR1 GENE; FEMALE; FLOW CYTOMETRY; GENE; GENE EXPRESSION; HOLSTEIN-FRIESIAN CATTLE; IKBKE GENE; MACROPHAGE; MICROARRAY ANALYSIS; MYCOBACTERIUM BOVIS; NFKB1 GENE; NONHUMAN; NUCLEOTIDE SEQUENCE; ONCOGENE MYC; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VIRULENCE; BACTERIAL SURVIVAL; BOVINE TUBERCULOSIS; CELL COUNT; DENSITY GRADIENT CENTRIFUGATION; DOWN REGULATION; GENE INTERACTION; GENE ONTOLOGY; GENE REGULATORY NETWORK; HOST PATHOGEN INTERACTION; HUMAN; IMMUNE RESPONSE; IMMUNOMODULATION; PROTEIN MICROARRAY; RNA EXTRACTION; UPREGULATION;

TRANSCRIPTOME;

EID: 84919451844     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2014.00422     Document Type: Article

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