Mangiferin ameliorates colitis by inhibiting IRAK1 phosphorylation in NF-κB and MAPK pathways

European Journal of Pharmacology

Volumn 740, Issue , 2014, Pages 652-661

  Jeong, Jin Ju ^a   Jang, Se Eun ^a   Hyam, Supriya R ^a   Han, Myung Joo ^a   Kim, Dong Hyun ^a  

^a Kyung Hee University   (South Korea)

Author keywords

Colitis; IRAK1; Macrophage; Mangiferin; NF B MAP kinase

Indexed keywords

CYCLOOXYGENASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 1; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MANGIFERIN; MESALAZINE; MITOGEN ACTIVATED PROTEIN KINASE; MYELOPEROXIDASE; PEPTIDOGLYCAN; SN 50; TOLL LIKE RECEPTOR 4; TRINITROBENZENESULFONIC ACID; TUMOR NECROSIS FACTOR ALPHA; ANTIINFLAMMATORY AGENT; CYTOKINE; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE; IRAK1 PROTEIN, MOUSE; XANTHONE DERIVATIVE;

ANEMARRHENA ASPHODELOIDES; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELLULAR DISTRIBUTION; COLITIS; COMBINATION CHEMOTHERAPY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DOWN REGULATION; DRUG DETERMINATION; DRUG EFFICACY; DRUG ISOLATION; DRUG POTENCY; DRUG POTENTIATION; DRUG PROTEIN BINDING; DRUG TARGETING; ENZYME INHIBITION; MACROPHAGE ACTIVATION; MALE; MANGO; MONOTHERAPY; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PLANT LEAF; PLANT ROOT; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; UPREGULATION; ANIMAL; C57BL MOUSE; CHEMICALLY INDUCED; DRUG EFFECTS; METABOLISM; PHOSPHORYLATION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; COLITIS; CYTOKINES; INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES; LIPOPOLYSACCHARIDES; MACROPHAGES, PERITONEAL; MALE; MICE, INBRED C57BL; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; PEPTIDOGLYCAN; PHOSPHORYLATION; TRINITROBENZENESULFONIC ACID; XANTHONES;

EID: 84919446380     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2014.06.013     Document Type: Article

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