메뉴 건너뛰기




Volumn 50, Issue 1, 2014, Pages 90-112

Conventional drug therapy for inflammatory bowel disease

Author keywords

Crohn's disease; Inflammatory bowel disease; Ulcerative colitis

Indexed keywords

ANTIINFECTIVE AGENT; ANTIINFLAMMATORY AGENT; GASTROINTESTINAL AGENT; IMMUNOSUPPRESSIVE AGENT; MONOCLONAL ANTIBODY;

EID: 84919443959     PISSN: 00365521     EISSN: 15027708     Source Type: Journal    
DOI: 10.3109/00365521.2014.968864     Document Type: Review
Times cited : (59)

References (210)
  • 1
    • 83755219473 scopus 로고    scopus 로고
    • Increasing incidence and prevalence of the inflammatory bowel diseases with time, based on systematic review
    • quiz e30
    • Molodecky NA, Soon IS, Rabi DM, Ghali WA, Ferris M, Chernoff G, et al. Increasing incidence and prevalence of the inflammatory bowel diseases with time, based on systematic review. Gastroenterology 2012;142:46-54.e42; quiz e30.
    • (2012) Gastroenterology , vol.142 , pp. 46-46e42
    • Molodecky, N.A.1    Soon, I.S.2    Rabi, D.M.3    Ghali, W.A.4    Ferris, M.5    Chernoff, G.6
  • 2
    • 79959216005 scopus 로고    scopus 로고
    • Genetics and pathogenesis of inflammatory bowel disease
    • Khor B, Gardet A, Xavier RJ. Genetics and pathogenesis of inflammatory bowel disease. Nature 2011;474:307-17.
    • (2011) Nature , vol.474 , pp. 307-317
    • Khor, B.1    Gardet, A.2    Xavier, R.J.3
  • 3
    • 84884273778 scopus 로고    scopus 로고
    • Advances in inflammatory bowel disease pathogenesis: Linking host genetics and the microbiome
    • Knights D, Lassen KG, Xavier RJ. Advances in inflammatory bowel disease pathogenesis: linking host genetics and the microbiome. Gut 2013;62:1505-10.
    • (2013) Gut , vol.62 , pp. 1505-1510
    • Knights, D.1    Lassen, K.G.2    Xavier, R.J.3
  • 4
    • 84869083669 scopus 로고    scopus 로고
    • Second European evidence-based consensus on the diagnosis and management of ulcerative colitis part 1: Definitions and diagnosis
    • Dignass A, Eliakim R, Magro F, Maaser C, Chowers Y, Geboes K, et al. Second European evidence-based consensus on the diagnosis and management of ulcerative colitis part 1: definitions and diagnosis. J Crohns Colitis 2012;6: 965-90.
    • (2012) J Crohns Colitis , vol.6 , pp. 965-990
    • Dignass, A.1    Eliakim, R.2    Magro, F.3    Maaser, C.4    Chowers, Y.5    Geboes, K.6
  • 5
    • 75149129948 scopus 로고    scopus 로고
    • The second European evidence-based Consensus on the diagnosis and management of Crohn's disease: Definitions and diagnosis
    • Van Assche G, Dignass A, Panes J, Beaugerie L, Karagiannis J, Allez M, et al. The second European evidence-based Consensus on the diagnosis and management of Crohn's disease: definitions and diagnosis. J Crohns Colitis 2010;4:7-27.
    • (2010) J Crohns Colitis , vol.4 , pp. 7-27
    • Van Assche, G.1    Dignass, A.2    Panes, J.3    Beaugerie, L.4    Karagiannis, J.5    Allez, M.6
  • 6
    • 84869089859 scopus 로고    scopus 로고
    • Second European evidence-based consensus on the diagnosis and management of ulcerative colitis part 2: Current management
    • Dignass A, Lindsay JO, Sturm A, Windsor A, Colombel JF, Allez M, et al. Second European evidence-based consensus on the diagnosis and management of ulcerative colitis part 2: current management. J Crohns Colitis 2012;6:991-1030.
    • (2012) J Crohns Colitis , vol.6 , pp. 991-1030
    • Dignass, A.1    Lindsay, J.O.2    Sturm, A.3    Windsor, A.4    Colombel, J.F.5    Allez, M.6
  • 7
    • 75149161836 scopus 로고    scopus 로고
    • The second European evidence-based Consensus on the diagnosis and management of Crohn's disease: Current management
    • Dignass A, Van Assche G, Lindsay JO, Lemann M, Soderholm J, Colombel JF, et al. The second European evidence-based Consensus on the diagnosis and management of Crohn's disease: current management. J Crohns Colitis 2010;4:28-62.
    • (2010) J Crohns Colitis , vol.4 , pp. 28-62
    • Dignass, A.1    Van Assche, G.2    Lindsay, J.O.3    Lemann, M.4    Soderholm, J.5    Colombel, J.F.6
  • 8
    • 77949271455 scopus 로고    scopus 로고
    • Ulcerative colitis practice guidelines in adults: American College of Gastroenterology, Practice Parameters Committee
    • quiz 24
    • Kornbluth A, Sachar DB. Ulcerative colitis practice guidelines in adults: American College Of Gastroenterology, Practice Parameters Committee. Am J Gastroenterol 2010;105:501-23; quiz 24.
    • (2010) Am J Gastroenterol , vol.105 , pp. 501-523
    • Kornbluth, A.1    Sachar, D.B.2
  • 10
    • 79953761841 scopus 로고    scopus 로고
    • Guidelines for the management of inflammatory bowel disease in adults
    • Mowat C, Cole A, Windsor A, Ahmad T, Arnott I, Driscoll R, et al. Guidelines for the management of inflammatory bowel disease in adults. Gut 2011;60:571-607.
    • (2011) Gut , vol.60 , pp. 571-607
    • Mowat, C.1    Cole, A.2    Windsor, A.3    Ahmad, T.4    Arnott, I.5    Driscoll, R.6
  • 11
    • 84884620960 scopus 로고    scopus 로고
    • Cause-specific mortality and 30-year relative survival of Crohn's disease and ulcerative colitis
    • Selinger CP, Andrews J, Dent OF, Norton I, Jones B, McDonald C, et al. Cause-specific mortality and 30-year relative survival of Crohn's disease and ulcerative colitis. Inflamm Bowel Dis 2013;19:1880-8.
    • (2013) Inflamm Bowel Dis , vol.19 , pp. 1880-1888
    • Selinger, C.P.1    Andrews, J.2    Dent, O.F.3    Norton, I.4    Jones, B.5    McDonald, C.6
  • 12
    • 79955557278 scopus 로고    scopus 로고
    • Conventional medical management of inflammatory bowel disease
    • Burger D, Travis S. Conventional medical management of inflammatory bowel disease. Gastroenterology 2011;140: 1827-37.e2.
    • (2011) Gastroenterology , vol.140 , pp. 1827-1827e2
    • Burger, D.1    Travis, S.2
  • 13
    • 78650000245 scopus 로고    scopus 로고
    • Review article: Explaining risks of inflammatory bowel disease therapy to patients
    • Siegel CA. Review article: explaining risks of inflammatory bowel disease therapy to patients. Aliment Pharmacol Ther 2011;33:23-32.
    • (2011) Aliment Pharmacol Ther , vol.33 , pp. 23-32
    • Siegel, C.A.1
  • 14
    • 84857051275 scopus 로고    scopus 로고
    • Shared decision making in inflammatory bowel disease: Helping patients understand the tradeoffs between treatment options
    • Siegel CA. Shared decision making in inflammatory bowel disease: helping patients understand the tradeoffs between treatment options. Gut 2012;61:459-65.
    • (2012) Gut , vol.61 , pp. 459-465
    • Siegel, C.A.1
  • 15
    • 33646778482 scopus 로고    scopus 로고
    • The Montreal classification of inflammatory bowel disease: Controversies, consensus, and implications
    • Satsangi J, Silverberg MS, Vermeire S, Colombel JF. The Montreal classification of inflammatory bowel disease: controversies, consensus, and implications. Gut 2006;55: 749-53.
    • (2006) Gut , vol.55 , pp. 749-753
    • Satsangi, J.1    Silverberg, M.S.2    Vermeire, S.3    Colombel, J.F.4
  • 16
    • 79955712974 scopus 로고    scopus 로고
    • Pediatric modification of the Montreal classification for inflammatory bowel disease: The Paris classification
    • Levine A, Griffiths A, Markowitz J, Wilson DC, Turner D, Russell RK, et al. Pediatric modification of the Montreal classification for inflammatory bowel disease: the Paris classification. Inflamm Bowel Dis 2011;17:1314-21.
    • (2011) Inflamm Bowel Dis , vol.17 , pp. 1314-1321
    • Levine, A.1    Griffiths, A.2    Markowitz, J.3    Wilson, D.C.4    Turner, D.5    Russell, R.K.6
  • 17
    • 84870631250 scopus 로고    scopus 로고
    • Postoperative recurrence of Crohn's disease: Impact of endoscopic monitoring and treatment step-up
    • De Cruz P, Bernardi MP, Kamm MA, Allen PB, Prideaux L, Williams J, et al. Postoperative recurrence of Crohn's disease: impact of endoscopic monitoring and treatment step-up. Colorectal Dis 2013;15:187-97.
    • (2013) Colorectal Dis , vol.15 , pp. 187-197
    • De Cruz, P.1    Bernardi, M.P.2    Kamm, M.A.3    Allen, P.B.4    Prideaux, L.5    Williams, J.6
  • 18
    • 84904504746 scopus 로고    scopus 로고
    • Smokingininflammatory bowel disease: Impact on disease course and insights into the aetiology of its effect
    • Parkes GC, Whelan K, Lindsay JO. Smokingininflammatory bowel disease: impact on disease course and insights into the aetiology of its effect. J Crohns Colitis 2014;8:717-25.
    • (2014) J Crohns Colitis , vol.8 , pp. 717-725
    • Parkes, G.C.1    Whelan, K.2    Lindsay, J.O.3
  • 22
    • 84855216805 scopus 로고    scopus 로고
    • Development of the first disability index for inflammatory bowel disease based on the international classification of functioning, disability and health
    • Peyrin-Biroulet L, Cieza A, Sandborn WJ, Coenen M, Chowers Y, Hibi T, et al. Development of the first disability index for inflammatory bowel disease based on the international classification of functioning, disability and health. Gut 2012;61:241-7.
    • (2012) Gut , vol.61 , pp. 241-247
    • Peyrin-Biroulet, L.1    Cieza, A.2    Sandborn, W.J.3    Coenen, M.4    Chowers, Y.5    Hibi, T.6
  • 25
    • 79954553840 scopus 로고    scopus 로고
    • Functional gastrointestinal disordersininflam-matory bowel disease: Impact on quality of life and psychological status
    • Bryant RV, van Langenberg DR, Holtmann GJ, Andrews JM. Functional gastrointestinal disordersininflam-matory bowel disease: impact on quality of life and psychological status. J Gastroenterol Hepatol 2011;26:916-23.
    • (2011) J Gastroenterol Hepatol , vol.26 , pp. 916-923
    • Bryant, R.V.1    Van Langenberg, D.R.2    Holtmann, G.J.3    Andrews, J.M.4
  • 26
    • 33847179443 scopus 로고    scopus 로고
    • A review of activity indices and efficacy end points for clinical trials of medical therapy in adults with ulcerative colitis
    • D'Haens G, Sandborn WJ, Feagan BG, Geboes K, Hanauer SB, Irvine EJ, et al. A review of activity indices and efficacy end points for clinical trials of medical therapy in adults with ulcerative colitis. Gastroenterology 2007;132: 763-86.
    • (2007) Gastroenterology , vol.132 , pp. 763-786
    • D'Haens, G.1    Sandborn, W.J.2    Feagan, B.G.3    Geboes, K.4    Hanauer, S.B.5    Irvine, E.J.6
  • 28
    • 84888400869 scopus 로고    scopus 로고
    • Clinical disease activity, C-reactive protein normalisation and mucosal healing in Crohn's disease in the SONIC trial
    • Peyrin-Biroulet L, Reinisch W, Colombel JF, Mantzaris GJ, Kornbluth A, Diamond R, et al. Clinical disease activity, C-reactive protein normalisation and mucosal healing in Crohn's disease in the SONIC trial. Gut 2014;63:88-95.
    • (2014) Gut , vol.63 , pp. 88-95
    • Peyrin-Biroulet, L.1    Reinisch, W.2    Colombel, J.F.3    Mantzaris, G.J.4    Kornbluth, A.5    Diamond, R.6
  • 29
    • 84857700568 scopus 로고    scopus 로고
    • Developing an instrument to assess the endoscopic severity of ulcerative colitis: The Ulcerative Colitis Endoscopic Index of Severity (UCEIS)
    • Travis SP, Schnell D, Krzeski P, Abreu MT, Altman DG, Colombel JF, et al. Developing an instrument to assess the endoscopic severity of ulcerative colitis: the Ulcerative Colitis Endoscopic Index of Severity (UCEIS). Gut 2012; 61:535-42.
    • (2012) Gut , vol.61 , pp. 535-542
    • Travis, S.P.1    Schnell, D.2    Krzeski, P.3    Abreu, M.T.4    Altman, D.G.5    Colombel, J.F.6
  • 31
    • 0035085024 scopus 로고    scopus 로고
    • The incidence of deep venous thrombosis and pulmonary embolism among patients with inflammatory bowel disease: A population-based cohort study
    • Bernstein CN, Blanchard JF, Houston DS, Wajda A. The incidence of deep venous thrombosis and pulmonary embolism among patients with inflammatory bowel disease: a population-based cohort study. Thromb Haemost 2001; 85:430-4.
    • (2001) Thromb Haemost , vol.85 , pp. 430-434
    • Bernstein, C.N.1    Blanchard, J.F.2    Houston, D.S.3    Wajda, A.4
  • 32
    • 84892879798 scopus 로고    scopus 로고
    • Thrombosis in inflammatory bowel disease: Are we tailoring prophylaxis to those most at risk?
    • Bryant RV, Jairath V, Curry N, Travis SP. Thrombosis in inflammatory bowel disease: are we tailoring prophylaxis to those most at risk? J Crohns Colitis 2014;8:166-71.
    • (2014) J Crohns Colitis , vol.8 , pp. 166-171
    • Bryant, R.V.1    Jairath, V.2    Curry, N.3    Travis, S.P.4
  • 33
    • 84879213600 scopus 로고    scopus 로고
    • Risk factors for osteoporosisin Crohn's disease: Infliximab, corticosteroids, body mass index, and age of onset
    • Azzopardi N, Ellul P. Risk factors for osteoporosisin Crohn's disease: infliximab, corticosteroids, body mass index, and age of onset. Inflamm Bowel Dis 2013;19:1173-8.
    • (2013) Inflamm Bowel Dis , vol.19 , pp. 1173-1178
    • Azzopardi, N.1    Ellul, P.2
  • 34
    • 80052698840 scopus 로고    scopus 로고
    • Assessment and management of low bone density in inflammatory bowel disease and performance of professional society guidelines
    • Etzel JP, Larson MF, Anawalt BD, Collins J, Dominitz JA. Assessment and management of low bone density in inflammatory bowel disease and performance of professional society guidelines. Inflamm Bowel Dis 2011;17:2122-9.
    • (2011) Inflamm Bowel Dis , vol.17 , pp. 2122-2129
    • Etzel, J.P.1    Larson, M.F.2    Anawalt, B.D.3    Collins, J.4    Dominitz, J.A.5
  • 37
    • 84875627084 scopus 로고    scopus 로고
    • Increase in bone mineral density in strictly treated Crohn's disease patients with concomitant calcium and vitamin D supplementation
    • Bakker SF, Dik VK, Witte BI, Lips P, Roos JC, Van Bodegraven AA. Increase in bone mineral density in strictly treated Crohn's disease patients with concomitant calcium and vitamin D supplementation. J Crohns Colitis 2013;7: 377-84.
    • (2013) J Crohns Colitis , vol.7 , pp. 377-384
    • Bakker, S.F.1    Dik, V.K.2    Witte, B.I.3    Lips, P.4    Roos, J.C.5    Van Bodegraven, A.A.6
  • 38
  • 39
    • 84901499277 scopus 로고    scopus 로고
    • Delving into disability in Crohn's disease: Dysregulation of molecular pathways may explain skeletal muscle loss in Crohn's disease
    • van Langenberg DR, Gatta PD, Hill B, Zacharewicz E, Gibson PR, Russell AP. Delving into disability in Crohn's disease: dysregulation of molecular pathways may explain skeletal muscle loss in Crohn's disease. J Crohns Colitis 2014;8:626-34.
    • (2014) J Crohns Colitis , vol.8 , pp. 626-634
    • Van Langenberg, D.R.1    Gatta, P.D.2    Hill, B.3    Zacharewicz, E.4    Gibson, P.R.5    Russell, A.P.6
  • 40
    • 84892880400 scopus 로고    scopus 로고
    • Objectively measured muscle fatigue in Crohn's disease: Correlation with self-reported fatigue and associated factors for clinical application
    • van Langenberg DR, Della Gatta P, Warmington SA, Kidgell DJ, Gibson PR, Russell AP. Objectively measured muscle fatigue in Crohn's disease: correlation with self-reported fatigue and associated factors for clinical application. J Crohns Colitis 2014;8:137-46.
    • (2014) J Crohns Colitis , vol.8 , pp. 137-146
    • Van Langenberg, D.R.1    Della Gatta, P.2    Warmington, S.A.3    Kidgell, D.J.4    Gibson, P.R.5    Russell, A.P.6
  • 41
    • 84899719594 scopus 로고    scopus 로고
    • Second European evidence-based consensus on the prevention, diagnosis and management of opportunistic infections in inflammatory bowel disease
    • Rahier JF, Magro F, Abreu C, Armuzzi A, Ben-Horin S, Chowers Y, et al. Second European evidence-based consensus on the prevention, diagnosis and management of opportunistic infections in inflammatory bowel disease. J Crohns Colitis 2014;8:443-68.
    • (2014) J Crohns Colitis , vol.8 , pp. 443-468
    • Rahier, J.F.1    Magro, F.2    Abreu, C.3    Armuzzi, A.4    Ben-Horin, S.5    Chowers, Y.6
  • 42
    • 84884162848 scopus 로고    scopus 로고
    • Implementing guidelines on the prevention of opportunistic infections in inflammatory bowel disease
    • Walsh AJ, Weltman M, Burger D, Vivekanandarajah S, Connor S, Howlett M, et al. Implementing guidelines on the prevention of opportunistic infections in inflammatory bowel disease. J Crohns Colitis 2013;7:e449-56.
    • (2013) J Crohns Colitis , vol.7 , pp. e449-e456
    • Walsh, A.J.1    Weltman, M.2    Burger, D.3    Vivekanandarajah, S.4    Connor, S.5    Howlett, M.6
  • 43
    • 84879894997 scopus 로고    scopus 로고
    • Moving towards disease modification in inflammatory bowel disease therapy
    • Allen PB, Peyrin-Biroulet L. Moving towards disease modification in inflammatory bowel disease therapy. Curr Opin Gastroenterol 2013;29:397-404.
    • (2013) Curr Opin Gastroenterol , vol.29 , pp. 397-404
    • Allen, P.B.1    Peyrin-Biroulet, L.2
  • 45
    • 80053130407 scopus 로고    scopus 로고
    • Early mucosal healing with infliximab is associated with improved long-term clinical outcomes in ulcerative colitis
    • Colombel JF, Rutgeerts P, Reinisch W, Esser D, Wang Y, Lang Y, et al. Early mucosal healing with infliximab is associated with improved long-term clinical outcomes in ulcerative colitis. Gastroenterology 2011;141:1194-201.
    • (2011) Gastroenterology , vol.141 , pp. 1194-1201
    • Colombel, J.F.1    Rutgeerts, P.2    Reinisch, W.3    Esser, D.4    Wang, Y.5    Lang, Y.6
  • 46
    • 84867027990 scopus 로고    scopus 로고
    • Mucosal healing in inflammatory bowel diseases: A systematic review
    • Neurath MF, Travis SP. Mucosal healing in inflammatory bowel diseases: a systematic review. Gut 2012;61:1619-35.
    • (2012) Gut , vol.61 , pp. 1619-1635
    • Neurath, M.F.1    Travis, S.P.2
  • 48
    • 84901231807 scopus 로고    scopus 로고
    • Histologic remission: The ultimate therapeutic goal in ulcerative colitis?
    • Peyrin-Biroulet L, Bressenot A, Kampman W. Histologic remission: the ultimate therapeutic goal in ulcerative colitis? Clin Gastroenterol Hepatol 2014;12:929-34.e2.
    • (2014) Clin Gastroenterol Hepatol , vol.12 , pp. 929-929e2
    • Peyrin-Biroulet, L.1    Bressenot, A.2    Kampman, W.3
  • 52
    • 84902129948 scopus 로고    scopus 로고
    • Genetic polymorphisms in metabolizing enzymes modifying the association between smoking and inflammatory bowel diseases
    • Ananthakrishnan AN, Nguyen DD, Sauk J, Yajnik V, Xavier RJ. Genetic polymorphisms in metabolizing enzymes modifying the association between smoking and inflammatory bowel diseases. Inflamm Bowel Dis 2014;20:783-9.
    • (2014) Inflamm Bowel Dis , vol.20 , pp. 783-789
    • Ananthakrishnan, A.N.1    Nguyen, D.D.2    Sauk, J.3    Yajnik, V.4    Xavier, R.J.5
  • 53
    • 84982333870 scopus 로고
    • Salazyopyrin, a new sulfanilamide preparation: A. Therapeutic results in rheumatic polyarthritis. B. Therapeutic results in ulcerative colitis. C. Toxic manifestations in treatment with sulfanilamide preparation
    • Svartz N. Salazyopyrin, a new sulfanilamide preparation: A. Therapeutic results in rheumatic polyarthritis. B. Therapeutic results in ulcerative colitis. C. Toxic manifestations in treatment with sulfanilamide preparation. Acta Med Scand 1942;110:557-90.
    • (1942) Acta Med Scand , vol.110 , pp. 557-590
    • Svartz, N.1
  • 54
    • 0018961746 scopus 로고
    • Effect of sulphapyridine, 5-aminosalicylic acid, and placebo in patients with idiopathic proctitis: A study to determine the active therapeutic moiety of sulphasalazine
    • van Hees PA, Bakker JH, van Tongeren JH. Effect of sulphapyridine, 5-aminosalicylic acid, and placebo in patients with idiopathic proctitis: a study to determine the active therapeutic moiety of sulphasalazine. Gut 1980;21: 632-5.
    • (1980) Gut , vol.21 , pp. 632-635
    • Van Hees, P.A.1    Bakker, J.H.2    Van Tongeren, J.H.3
  • 55
    • 84873156311 scopus 로고    scopus 로고
    • Oral 5-aminosalicylic acid for induction of remission in ulcerative colitis
    • Feagan BG, Macdonald JK. Oral 5-aminosalicylic acid for induction of remission in ulcerative colitis. Cochrane Database Syst Rev 2012;10:CD000543.
    • (2012) Cochrane Database Syst Rev , vol.10 , pp. CD000543
    • Feagan, B.G.1    MacDonald, J.K.2
  • 56
    • 0020064534 scopus 로고
    • Sulfasalazine intolerance. A retrospective survey of the reasons for discontinuing treatment with sulfa-salazine in patients with chronic inflammatory bowel disease
    • Nielsen OH. Sulfasalazine intolerance. A retrospective survey of the reasons for discontinuing treatment with sulfa-salazine in patients with chronic inflammatory bowel disease. Scand J Gastroenterol 1982;17:389-93.
    • (1982) Scand J Gastroenterol , vol.17 , pp. 389-393
    • Nielsen, O.H.1
  • 57
    • 0008690916 scopus 로고
    • Cortisone in ulcerative colitis; Final report on a therapeutic trial
    • Truelove SC, Witts LJ. Cortisone in ulcerative colitis; final report on a therapeutic trial. BMJ 1955;2:1041-8.
    • (1955) BMJ , vol.2 , pp. 1041-1048
    • Truelove, S.C.1    Witts, L.J.2
  • 58
    • 84879236559 scopus 로고    scopus 로고
    • Long-term mesalamine maintenance in ulcerative colitis: Which is more important? Adherence or daily dose
    • Khan N, Abbas AM, Koleva YN, Bazzano LA. Long-term mesalamine maintenance in ulcerative colitis: which is more important? Adherence or daily dose. Inflamm Bowel Dis 2013;19:1123-9.
    • (2013) Inflamm Bowel Dis , vol.19 , pp. 1123-1129
    • Khan, N.1    Abbas, A.M.2    Koleva, Y.N.3    Bazzano, L.A.4
  • 59
    • 84864991833 scopus 로고    scopus 로고
    • Once daily oral mesalamine compared to conventional dosing for induction and maintenance of remission in ulcerative colitis: A systematic review and meta-analysis
    • Feagan BG, MacDonald JK. Once daily oral mesalamine compared to conventional dosing for induction and maintenance of remission in ulcerative colitis: a systematic review and meta-analysis. Inflamm Bowel Dis 2012;18:1785-94.
    • (2012) Inflamm Bowel Dis , vol.18 , pp. 1785-1794
    • Feagan, B.G.1    MacDonald, J.K.2
  • 60
    • 84875229233 scopus 로고    scopus 로고
    • Randomised clinical trial: Once-vs twice-daily prolonged-release mesalazine for active ulcera-tive colitis
    • Flourie B, Hagege H, Tucat G, Maetz D, Hebuterne X, Kuyvenhoven JP, et al. Randomised clinical trial: once-vs. twice-daily prolonged-release mesalazine for active ulcera-tive colitis. Aliment Pharmacol Ther 2013;37:767-75.
    • (2013) Aliment Pharmacol Ther , vol.37 , pp. 767-775
    • Flourie, B.1    Hagege, H.2    Tucat, G.3    Maetz, D.4    Hebuterne, X.5    Kuyvenhoven, J.P.6
  • 61
    • 79952449301 scopus 로고    scopus 로고
    • A multicenter, randomized study to evaluate the efficacy and safetyofmesalamine suppositories1gatbedtime and 500 mg Twice daily in patients with active mild-to-moderate ulcerative proctitis
    • Lamet M. A multicenter, randomized study to evaluate the efficacy and safetyofmesalamine suppositories1gatbedtime and 500 mg Twice daily in patients with active mild-to-moderate ulcerative proctitis. Dig Dis Sci 2011;56:513-22.
    • (2011) Dig Dis Sci , vol.56 , pp. 513-522
    • Lamet, M.1
  • 62
    • 84866428073 scopus 로고    scopus 로고
    • Long-term oral mesalazine adherence and the risk of disease flare in ulcerative colitis: Nationwide 10-year retrospective cohort from the veterans affairs healthcare system
    • Khan N, Abbas AM, Bazzano LA, Koleva YN, Krousel-Wood M. Long-term oral mesalazine adherence and the risk of disease flare in ulcerative colitis: nationwide 10-year retrospective cohort from the veterans affairs healthcare system. Aliment Pharmacol Ther 2012;36:755-64.
    • (2012) Aliment Pharmacol Ther , vol.36 , pp. 755-764
    • Khan, N.1    Abbas, A.M.2    Bazzano, L.A.3    Koleva, Y.N.4    Krousel-Wood, M.5
  • 63
    • 84884666562 scopus 로고    scopus 로고
    • Are there any differences in the efficacy and safety of different formulations of Oral 5-ASA used for induction and maintenance of remission in ulcerative colitis? Evidence from cochrane reviews
    • Feagan BG, Chande N, MacDonald JK. Are there any differences in the efficacy and safety of different formulations of Oral 5-ASA used for induction and maintenance of remission in ulcerative colitis? evidence from cochrane reviews. Inflamm Bowel Dis 2013;19:2031-40.
    • (2013) Inflamm Bowel Dis , vol.19 , pp. 2031-2040
    • Feagan, B.G.1    Chande, N.2    MacDonald, J.K.3
  • 64
  • 65
    • 84872145972 scopus 로고    scopus 로고
    • Second European evidence-based consensus on the diagnosis and management of ulcerative colitis part 3: Special situations
    • Van Assche G, Dignass A, Bokemeyer B, Danese S, Gionchetti P, Moser G, et al. Second European evidence-based consensus on the diagnosis and management of ulcerative colitis part 3: special situations. J Crohns Colitis 2013;7:1-33.
    • (2013) J Crohns Colitis , vol.7 , pp. 1-33
    • Van Assche, G.1    Dignass, A.2    Bokemeyer, B.3    Danese, S.4    Gionchetti, P.5    Moser, G.6
  • 66
    • 34250883817 scopus 로고    scopus 로고
    • MMX Multi Matrix System mesala-zine for the induction of remission in patients with mild-to-moderate ulcerative colitis: A combined analysis of two randomized, double-blind, placebo-controlled trials
    • Sandborn WJ, Kamm MA, Lichtenstein GR, Lyne A, Butler T, Joseph RE. MMX Multi Matrix System mesala-zine for the induction of remission in patients with mild-to-moderate ulcerative colitis: a combined analysis of two randomized, double-blind, placebo-controlled trials. Aliment Pharmacol Ther 2007;26:205-15.
    • (2007) Aliment Pharmacol Ther , vol.26 , pp. 205-215
    • Sandborn, W.J.1    Kamm, M.A.2    Lichtenstein, G.R.3    Lyne, A.4    Butler, T.5    Joseph, R.E.6
  • 68
    • 39149118880 scopus 로고    scopus 로고
    • Delayed-release oral mesalamine 4.8 g/day (800 mg tablets) compared to 2.4 g/day (400 mg tablets) for the treatment of mildly to moderately active ulcerative colitis: The ASCEND i trial
    • Hanauer SB, Sandborn WJ, Dallaire C, Archambault A, Yacyshyn B, Yeh C, et al. Delayed-release oral mesalamine 4.8 g/day (800 mg tablets) compared to 2.4 g/day (400 mg tablets) for the treatment of mildly to moderately active ulcerative colitis: the ASCEND I trial. Can J Gastroenterol 2007;21:827-34.
    • (2007) Can J Gastroenterol , vol.21 , pp. 827-834
    • Hanauer, S.B.1    Sandborn, W.J.2    Dallaire, C.3    Archambault, A.4    Yacyshyn, B.5    Yeh, C.6
  • 69
    • 33644653559 scopus 로고    scopus 로고
    • Delayed-release oral mesalamine at 4.8 g/day (800 mg tablet) for the treatment of moderately active ulcerative colitis: The ASCEND II trial
    • Hanauer SB, Sandborn WJ, Kornbluth A, Katz S, Safdi M, Woogen S, et al. Delayed-release oral mesalamine at 4.8 g/day (800 mg tablet) for the treatment of moderately active ulcerative colitis: the ASCEND II trial. Am J Gastroenterol 2005;100:2478-85.
    • (2005) Am J Gastroenterol , vol.100 , pp. 2478-2485
    • Hanauer, S.B.1    Sandborn, W.J.2    Kornbluth, A.3    Katz, S.4    Safdi, M.5    Woogen, S.6
  • 70
    • 70649110836 scopus 로고    scopus 로고
    • Delayed-release oral mesalamine 4.8 g/day (800-mgtablet)iseffectiveforpatientswithmoderately active ulcerativecolitis
    • Sandborn WJ, Regula J, Feagan BG, Belousova E, Jojic N, Lukas M, et al. Delayed-release oral mesalamine 4.8 g/day (800-mgtablet)iseffectiveforpatientswithmoderately active ulcerativecolitis.Gastroenterology2009;137:1934-43;e1-3.
    • (2009) Gastroenterology , vol.137 , pp. 1934e1-1943e3
    • Sandborn, W.J.1    Regula, J.2    Feagan, B.G.3    Belousova, E.4    Jojic, N.5    Lukas, M.6
  • 71
    • 21044433011 scopus 로고    scopus 로고
    • Combined oral and enema treatment with Pentasa (mesalazine) is superior to oral therapy alone in patients with extensive mild/moderate active ulcerative colitis: A randomised, double blind, placebo controlled study
    • Marteau P, Probert CS, Lindgren S, Gassul M, Tan TG, Dignass A, et al. Combined oral and enema treatment with Pentasa (mesalazine) is superior to oral therapy alone in patients with extensive mild/moderate active ulcerative colitis: a randomised, double blind, placebo controlled study. Gut 2005;54:960-5.
    • (2005) Gut , vol.54 , pp. 960-965
    • Marteau, P.1    Probert, C.S.2    Lindgren, S.3    Gassul, M.4    Tan, T.G.5    Dignass, A.6
  • 72
    • 84856699125 scopus 로고    scopus 로고
    • Efficacy of oral vs topical, or combined oral and topical 5-aminosalicylates, in Ulcerative Colitis: Systematic review and meta-analysis
    • author reply 77
    • Ford AC, Khan KJ, Achkar JP, Moayyedi P. Efficacy of oral vs. topical, or combined oral and topical 5-aminosalicylates, in Ulcerative Colitis: systematic review and meta-analysis. Am J Gastroenterol 2012;107:167-76; author reply 77.
    • (2012) Am J Gastroenterol , vol.107 , pp. 167-176
    • Ford, A.C.1    Khan, K.J.2    Achkar, J.P.3    Moayyedi, P.4
  • 73
    • 84894253249 scopus 로고    scopus 로고
    • Combined oral and rectal mesalazine for the treatment of mild-to-moderately active ulcerative colitis: Rapid symptom resolution and improvements in quality of life
    • Probert CS, Dignass AU, Lindgren S, Oudkerk Pool M, Marteau P. Combined oral and rectal mesalazine for the treatment of mild-to-moderately active ulcerative colitis: rapid symptom resolution and improvements in quality of life. J Crohns Colitis 2014;8:200-7.
    • (2014) J Crohns Colitis , vol.8 , pp. 200-207
    • Probert, C.S.1    Dignass, A.U.2    Lindgren, S.3    Oudkerk Pool, M.4    Marteau, P.5
  • 74
    • 0033950973 scopus 로고    scopus 로고
    • Limited exposure of the healthy distal colon to orally-dosed formulation is further exaggerated in active left-sided ulcerative colitis
    • Hebden JM, Blackshaw PE, Perkins AC, Wilson CG, Spiller RC. Limited exposure of the healthy distal colon to orally-dosed formulation is further exaggerated in active left-sided ulcerative colitis. Aliment Pharmacol Ther 2000; 14:155-61.
    • (2000) Aliment Pharmacol Ther , vol.14 , pp. 155-161
    • Hebden, J.M.1    Blackshaw, P.E.2    Perkins, A.C.3    Wilson, C.G.4    Spiller, R.C.5
  • 77
    • 58149401224 scopus 로고    scopus 로고
    • Mesalamine foam enema versus mesalamine liquid enema in active left-sided ulcerative colitis
    • Cortot A, Maetz D, Degoutte E, Delette O, Meunier P, Tan G, et al. Mesalamine foam enema versus mesalamine liquid enema in active left-sided ulcerative colitis. Am J Gastroenterol 2008;103:3106-14.
    • (2008) Am J Gastroenterol , vol.103 , pp. 3106-3114
    • Cortot, A.1    Maetz, D.2    Degoutte, E.3    Delette, O.4    Meunier, P.5    Tan, G.6
  • 80
    • 84879786241 scopus 로고    scopus 로고
    • Randomised clinical trial: Evaluation of the efficacy of mesalazine (mesalamine) suppositories in patients with ulcerative colitis and active rectal inflammation - A placebo-controlled study
    • Watanabe M, Nishino H, Sameshima Y, Ota A, Nakamura S, Hibi T. Randomised clinical trial: evaluation of the efficacy of mesalazine (mesalamine) suppositories in patients with ulcerative colitis and active rectal inflammation-a placebo-controlled study. Aliment Pharmacol Ther 2013;38:264-73.
    • (2013) Aliment Pharmacol Ther , vol.38 , pp. 264-273
    • Watanabe, M.1    Nishino, H.2    Sameshima, Y.3    Ota, A.4    Nakamura, S.5    Hibi, T.6
  • 81
    • 0030848283 scopus 로고    scopus 로고
    • Rectal corticosteroids versus alternative treatments in ulcerative colitis: A meta-analysis
    • Marshall JK, Irvine EJ. Rectal corticosteroids versus alternative treatments in ulcerative colitis: a meta-analysis. Gut 1997;40:775-81.
    • (1997) Gut , vol.40 , pp. 775-781
    • Marshall, J.K.1    Irvine, E.J.2
  • 82
    • 0029901887 scopus 로고    scopus 로고
    • Beclomethasone dipropionate (3 mg) versus 5-aminosalicylic acid (2 g) versus the combination of both (3 mg/2 g) as retention enemas in active ulcerative proctitis
    • Mulder CJ, Fockens P, Meijer JW, van der Heide H, Wiltink EH, Tytgat GN. Beclomethasone dipropionate (3 mg) versus 5-aminosalicylic acid (2 g) versus the combination of both (3 mg/2 g) as retention enemas in active ulcerative proctitis. Eur J Gastroenterol Hepatol 1996;8: 549-53.
    • (1996) Eur J Gastroenterol Hepatol , vol.8 , pp. 549-553
    • Mulder, C.J.1    Fockens, P.2    Meijer, J.W.3    Van Der Heide, H.4    Wiltink, E.H.5    Tytgat, G.N.6
  • 84
    • 0030827118 scopus 로고    scopus 로고
    • A double-blind comparison of oral versus rectal mesalamine versus combination therapy in the treatment of distal ulcerative colitis
    • Safdi M, DeMicco M, Sninsky C, Banks P, Wruble L, Deren J, et al. A double-blind comparison of oral versus rectal mesalamine versus combination therapy in the treatment of distal ulcerative colitis. Am J Gastroenterol 1997; 92:1867-71.
    • (1997) Am J Gastroenterol , vol.92 , pp. 1867-1871
    • Safdi, M.1    Demicco, M.2    Sninsky, C.3    Banks, P.4    Wruble, L.5    Deren, J.6
  • 87
    • 2342433583 scopus 로고    scopus 로고
    • Oral Pentasa in the treatment of active Crohn's disease: A meta-analysis of double-blind, placebo-controlled trials
    • Hanauer SB, Stromberg U. Oral Pentasa in the treatment of active Crohn's disease: a meta-analysis of double-blind, placebo-controlled trials. Clin Gastroenterol Hepatol 2004;2:379-88.
    • (2004) Clin Gastroenterol Hepatol , vol.2 , pp. 379-388
    • Hanauer, S.B.1    Stromberg, U.2
  • 88
    • 79952196928 scopus 로고    scopus 로고
    • Aminosalicylates for induction of remission or response in Crohn's disease
    • Lim WC, Hanauer S. Aminosalicylates for induction of remission or response in Crohn's disease. Cochrane Database Syst Rev 2010:CD008870.
    • (2010) Cochrane Database Syst Rev , pp. CD008870
    • Lim, W.C.1    Hanauer, S.2
  • 89
    • 84884216502 scopus 로고    scopus 로고
    • Management of postoperative recurrence of Crohn's disease
    • van Lent AU, D'Haens GR. Management of postoperative recurrence of Crohn's disease. Dig Dis 2013;31:222-8.
    • (2013) Dig Dis , vol.31 , pp. 222-228
    • Van Lent, A.U.1    D'Haens, G.R.2
  • 91
    • 0037253045 scopus 로고    scopus 로고
    • Systematic review: The phar-macokinetic profiles of oral mesalazine formulations and mesalazine pro-drugs used in the management of ulcerative colitis
    • Sandborn WJ, Hanauer SB. Systematic review: the phar-macokinetic profiles of oral mesalazine formulations and mesalazine pro-drugs used in the management of ulcerative colitis. Aliment Pharmacol Ther 2003;17:29-42.
    • (2003) Aliment Pharmacol Ther , vol.17 , pp. 29-42
    • Sandborn, W.J.1    Hanauer, S.B.2
  • 92
    • 2942587176 scopus 로고    scopus 로고
    • 5-ami-nosalicylic acids and the risk of renal disease: A large British epidemiologic study
    • Van Staa TP, Travis S, Leufkens HG, Logan RF. 5-ami-nosalicylic acids and the risk of renal disease: a large British epidemiologic study. Gastroenterology 2004;126:1733-9.
    • (2004) Gastroenterology , vol.126 , pp. 1733-1739
    • Van Staa, T.P.1    Travis, S.2    Leufkens, H.G.3    Logan, R.F.4
  • 93
    • 0036786888 scopus 로고    scopus 로고
    • Sulphasalazine and mesala-zine: Serious adverse reactions re-evaluated on the basis of suspected adverse reaction reports to the Committee on Safety of Medicines
    • Ransford RA, Langman MJ. Sulphasalazine and mesala-zine: serious adverse reactions re-evaluated on the basis of suspected adverse reaction reports to the Committee on Safety of Medicines. Gut 2002;51:536-9.
    • (2002) Gut , vol.51 , pp. 536-539
    • Ransford, R.A.1    Langman, M.J.2
  • 94
    • 75149116327 scopus 로고    scopus 로고
    • The second European evidence-based Consensus on the diagnosis and management of Crohn's disease: Special situations
    • Van Assche G, Dignass A, Reinisch W, van der Woude CJ, Sturm A, De Vos M, et al. The second European evidence-based Consensus on the diagnosis and management of Crohn's disease: special situations. J Crohns Colitis 2010; 4:63-101.
    • (2010) J Crohns Colitis , vol.4 , pp. 63-101
    • Van Assche, G.1    Dignass, A.2    Reinisch, W.3    Van Der Woude, C.J.4    Sturm, A.5    De Vos, M.6
  • 96
    • 84893546852 scopus 로고    scopus 로고
    • Long-term safety and efficacy of budesonide in the treatment of ulcerative colitis
    • Iborra M, Alvarez-Sotomayor D, Nos P. Long-term safety and efficacy of budesonide in the treatment of ulcerative colitis. Clin Exp Gastroenterol 2014;7:39-46.
    • (2014) Clin Exp Gastroenterol , vol.7 , pp. 39-46
    • Iborra, M.1    Alvarez-Sotomayor, D.2    Nos, P.3
  • 97
    • 0023203059 scopus 로고
    • A controlled randomized trial of budesonide versus prednisolone retention enemas in active distal ulcer-ative colitis
    • Danielsson A, Hellers G, Lyrenas E, Lofberg R, Nilsson A, Olsson O, et al. A controlled randomized trial of budesonide versus prednisolone retention enemas in active distal ulcer-ative colitis. Scand J Gastroenterol 1987;22:987-92.
    • (1987) Scand J Gastroenterol , vol.22 , pp. 987-992
    • Danielsson, A.1    Hellers, G.2    Lyrenas, E.3    Lofberg, R.4    Nilsson, A.5    Olsson, O.6
  • 100
    • 84868127664 scopus 로고    scopus 로고
    • Once-daily budesonide MMX(R) extended-release tablets induce remission in patients with mild to moderate ulcerative colitis: Results from the CORE i study
    • Sandborn WJ, Travis S, Moro L, Jones R, Gautille T, Bagin R, et al. Once-daily budesonide MMX(R) extended-release tablets induce remission in patients with mild to moderate ulcerative colitis: results from the CORE I study. Gastroenterology 2012;143:1218-26; e1-2.
    • (2012) Gastroenterology , vol.143 , pp. 1218e1-1226e2
    • Sandborn, W.J.1    Travis, S.2    Moro, L.3    Jones, R.4    Gautille, T.5    Bagin, R.6
  • 101
    • 84893767519 scopus 로고    scopus 로고
    • Once-daily budesonide MMX in active, mild-to-moderate ulcerative colitis: Results from the randomised CORE II study
    • Travis SP, Danese S, Kupcinskas L, Alexeeva O, D'Haens G, Gibson PR, et al. Once-daily budesonide MMX in active, mild-to-moderate ulcerative colitis: results from the randomised CORE II study. Gut 2014;63:433-41.
    • (2014) Gut , vol.63 , pp. 433-441
    • Travis, S.P.1    Danese, S.2    Kupcinskas, L.3    Alexeeva, O.4    D'Haens, G.5    Gibson, P.R.6
  • 102
    • 6944250136 scopus 로고    scopus 로고
    • How effective are the usual treatments for ulcerative colitis?
    • Bebb JR, Scott BB. How effective are the usual treatments for ulcerative colitis? Aliment Pharmacol Ther 2004;20: 143-9.
    • (2004) Aliment Pharmacol Ther , vol.20 , pp. 143-149
    • Bebb, J.R.1    Scott, B.B.2
  • 103
    • 0000206329 scopus 로고
    • An assessment of prednisone, salazopyrin, and topical hydrocortisone hemisuccinate used as out-patient treatment for ulcerative colitis
    • Lennard-Jones JE, Longmore AJ, Newell AC, Wilson CW, Jones FA. An assessment of prednisone, salazopyrin, and topical hydrocortisone hemisuccinate used as out-patient treatment for ulcerative colitis. Gut 1960;1:217-22.
    • (1960) Gut , vol.1 , pp. 217-222
    • Lennard-Jones, J.E.1    Longmore, A.J.2    Newell, A.C.3    Wilson, C.W.4    Jones, F.A.5
  • 104
    • 79953777773 scopus 로고    scopus 로고
    • Glucocorticosteroid therapyininflammatory bowel disease: Systematic review and meta-analysis
    • quiz 600
    • Ford AC, Bernstein CN, Khan KJ, Abreu MT, Marshall JK, Talley NJ, et al. Glucocorticosteroid therapyininflammatory bowel disease: systematic review and meta-analysis. Am J Gastroenterol 2011;106:590-9; quiz 600.
    • (2011) Am J Gastroenterol , vol.106 , pp. 590-599
    • Ford, A.C.1    Bernstein, C.N.2    Khan, K.J.3    Abreu, M.T.4    Marshall, J.K.5    Talley, N.J.6
  • 105
    • 73649164155 scopus 로고
    • Comparison of corticosteroid and sulphasalazine therapy in ulcerative colitis
    • Truelove SC, Watkinson G, Draper G. Comparison of corticosteroid and sulphasalazine therapy in ulcerative colitis. BMJ 1962;2:1708-11.
    • (1962) BMJ , vol.2 , pp. 1708-1711
    • Truelove, S.C.1    Watkinson, G.2    Draper, G.3
  • 106
    • 0034903792 scopus 로고    scopus 로고
    • The natural history of corticosteroid therapy for inflammatory bowel disease: A population-based study
    • FaubionWAJr, LoftusEVJr, Harmsen WS, Zinsmeister AR, Sandborn WJ. The natural history of corticosteroid therapy for inflammatory bowel disease: a population-based study. Gastroenterology 2001;121:255-60.
    • (2001) Gastroenterology , vol.121 , pp. 255-260
    • Loftusevjr, F.1    Harmsen, W.S.2    Zinsmeister, A.R.3    Sandborn, W.J.4
  • 107
    • 0000766395 scopus 로고
    • Out-patient treatment of ulcerative colitis. Comparison between three doses of oral prednisone
    • Baron JH, Connell AM, Kanaghinis TG, Lennard-Jones JE, Jones AF. Out-patient treatment of ulcerative colitis. Comparison between three doses of oral prednisone. BMJ 1962; 2:441-3.
    • (1962) BMJ , vol.2 , pp. 441-443
    • Baron, J.H.1    Connell, A.M.2    Kanaghinis, T.G.3    Lennard-Jones, J.E.4    Jones, A.F.5
  • 111
    • 84898853766 scopus 로고    scopus 로고
    • Review article: Integrating budesonide-MMX into treatment algorithms for mild-to-moderate ulcerative colitis
    • Danese S, Siegel CA, Peyrin-Biroulet L. Review article: integrating budesonide-MMX into treatment algorithms for mild-to-moderate ulcerative colitis. Aliment Pharmacol Ther 2014;39:1095-103.
    • (2014) Aliment Pharmacol Ther , vol.39 , pp. 1095-1103
    • Danese, S.1    Siegel, C.A.2    Peyrin-Biroulet, L.3
  • 115
    • 0043033175 scopus 로고    scopus 로고
    • Corticosteroids and immunomodulators: Postoperative infectious complication risk in inflammatory bowel disease patients
    • Aberra FN, Lewis JD, Hass D, Rombeau JL, Osborne B, Lichtenstein GR. Corticosteroids and immunomodulators: postoperative infectious complication risk in inflammatory bowel disease patients. Gastroenterology 2003;125:320-7.
    • (2003) Gastroenterology , vol.125 , pp. 320-327
    • Aberra, F.N.1    Lewis, J.D.2    Hass, D.3    Rombeau, J.L.4    Osborne, B.5    Lichtenstein, G.R.6
  • 116
    • 84866122837 scopus 로고    scopus 로고
    • Serious infection and mortality in patients with Crohn's disease: More than 5 years of follow-up in the TREAT registry
    • Lichtenstein GR, Feagan BG, Cohen RD, Salzberg BA, Diamond RH, Price S, et al. Serious infection and mortality in patients with Crohn's disease: more than 5 years of follow-up in the TREAT registry. Am J Gastroenterol 2012;107:1409-22.
    • (2012) Am J Gastroenterol , vol.107 , pp. 1409-1422
    • Lichtenstein, G.R.1    Feagan, B.G.2    Cohen, R.D.3    Salzberg, B.A.4    Diamond, R.H.5    Price, S.6
  • 117
    • 0014966572 scopus 로고
    • Azathioprine in Crohn's disease
    • Rhodes J, Bainton D, Beck P. Azathioprine in Crohn's disease. Lancet 1970;2:1142.
    • (1970) Lancet , vol.2 , pp. 1142
    • Rhodes, J.1    Bainton, D.2    Beck, P.3
  • 119
    • 0028899859 scopus 로고
    • Methotrexate for the treatment of Crohn's disease. The North American Crohn's Study Group Investigators
    • Feagan BG, Rochon J, Fedorak RN, Irvine EJ, Wild G, Sutherland L, et al. Methotrexate for the treatment of Crohn's disease. The North American Crohn's Study Group Investigators. N Engl J Med 1995;332:292-7.
    • (1995) N Engl J Med , vol.332 , pp. 292-297
    • Feagan, B.G.1    Rochon, J.2    Fedorak, R.N.3    Irvine, E.J.4    Wild, G.5    Sutherland, L.6
  • 120
    • 29244457275 scopus 로고    scopus 로고
    • Randomised controlled trial of azathio-prine and 5-aminosalicylic acid for treatment of steroid dependent ulcerative colitis
    • Ardizzone S, Maconi G, Russo A, Imbesi V, Colombo E, Bianchi Porro G. Randomised controlled trial of azathio-prine and 5-aminosalicylic acid for treatment of steroid dependent ulcerative colitis. Gut 2006;55:47-53.
    • (2006) Gut , vol.55 , pp. 47-53
    • Ardizzone, S.1    MacOni, G.2    Russo, A.3    Imbesi, V.4    Colombo, E.5    Bianchi Porro, G.6
  • 121
    • 34247181314 scopus 로고    scopus 로고
    • Colectomy rate in steroid-refractory colitis initially responsive to cyclosporin: A long-term retrospective cohort study
    • Actis GC, Fadda M, David E, Sapino A. Colectomy rate in steroid-refractory colitis initially responsive to cyclosporin: a long-term retrospective cohort study. BMC Gastroenterol 2007;7:13.
    • (2007) BMC Gastroenterol , vol.7 , pp. 13
    • Actis, G.C.1    Fadda, M.2    David, E.3    Sapino, A.4
  • 124
    • 0036278519 scopus 로고    scopus 로고
    • The efficacy of aza-thioprine for the treatment of inflammatory bowel disease: A 30 year review
    • Fraser AG, Orchard TR, Jewell DP. The efficacy of aza-thioprine for the treatment of inflammatory bowel disease: a 30 year review. Gut 2002;50:485-9.
    • (2002) Gut , vol.50 , pp. 485-489
    • Fraser, A.G.1    Orchard, T.R.2    Jewell, D.P.3
  • 125
    • 84881273549 scopus 로고    scopus 로고
    • Azathioprine or 6-mercaptopurine for induction of remission in Crohn's disease
    • Chande N, Tsoulis DJ, MacDonald JK. Azathioprine or 6-mercaptopurine for induction of remission in Crohn's disease. Cochrane Database Syst Rev 2013;4:CD000545.
    • (2013) Cochrane Database Syst Rev , vol.4 , pp. CD000545
    • Chande, N.1    Tsoulis, D.J.2    MacDonald, J.K.3
  • 126
    • 84884369477 scopus 로고    scopus 로고
    • Early administration of azathioprine vs conventional management of Crohn's Disease: A randomized controlled trial
    • e2; quiz e14-5
    • Cosnes J, Bourrier A, Laharie D, Nahon S, Bouhnik Y, Carbonnel F, et al. Early administration of azathioprine vs conventional management of Crohn's Disease: a randomized controlled trial. Gastroenterology 2013;145:758-65. e2; quiz e14-5.
    • (2013) Gastroenterology , vol.145 , pp. 758-765
    • Cosnes, J.1    Bourrier, A.2    Laharie, D.3    Nahon, S.4    Bouhnik, Y.5    Carbonnel, F.6
  • 127
  • 129
    • 84891935282 scopus 로고    scopus 로고
    • The role of thiopurines in reducing the need for surgical resection in Crohn's disease: A systematic review and meta-analysis
    • quiz 5
    • Chatu S, Subramanian V, Saxena S, Pollok RC. The role of thiopurines in reducing the need for surgical resection in Crohn's disease: a systematic review and meta-analysis. Am J Gastroenterol 2014;109:23-34; quiz 5.
    • (2014) Am J Gastroenterol , vol.109 , pp. 23-34
    • Chatu, S.1    Subramanian, V.2    Saxena, S.3    Pollok, R.C.4
  • 132
    • 84879107120 scopus 로고    scopus 로고
    • Methotrexate in ulcerative colitis: A nationwide retrospective cohort from the Veterans Affairs Health Care System
    • Khan N, Abbas AM, Moehlen M, Balart L. Methotrexate in ulcerative colitis: a nationwide retrospective cohort from the Veterans Affairs Health Care System. Inflamm Bowel Dis 2013;19:1379-83.
    • (2013) Inflamm Bowel Dis , vol.19 , pp. 1379-1383
    • Khan, N.1    Abbas, A.M.2    Moehlen, M.3    Balart, L.4
  • 133
    • 68949209778 scopus 로고    scopus 로고
    • Efficacy of methotrexate in Crohn's disease and ulcerative colitis patients unresponsive or intolerant to azathioprine/mercaptopurine
    • Wahed M, Louis-Auguste JR, Baxter LM, Limdi JK, McCartney SA, Lindsay JO, et al. Efficacy of methotrexate in Crohn's disease and ulcerative colitis patients unresponsive or intolerant to azathioprine/mercaptopurine. Aliment Pharmacol Ther 2009;30:614-20.
    • (2009) Aliment Pharmacol Ther , vol.30 , pp. 614-620
    • Wahed, M.1    Louis-Auguste, J.R.2    Baxter, L.M.3    Limdi, J.K.4    McCartney, S.A.5    Lindsay, J.O.6
  • 135
    • 0034214336 scopus 로고    scopus 로고
    • A comparison of methotrexate with placebo for the maintenance of remission in Crohn's disease. North American Crohn's Study Group Investigators
    • Feagan BG, Fedorak RN, Irvine EJ, Wild G, Sutherland L, Steinhart AH, et al. A comparison of methotrexate with placebo for the maintenance of remission in Crohn's disease. North American Crohn's Study Group Investigators. N Engl J Med 2000;342:1627-32.
    • (2000) N Engl J Med , vol.342 , pp. 1627-1632
    • Feagan, B.G.1    Fedorak, R.N.2    Irvine, E.J.3    Wild, G.4    Sutherland, L.5    Steinhart, A.H.6
  • 136
    • 84879102390 scopus 로고    scopus 로고
    • Safety of thiopurine therapy in inflammatory bowel disease: Long-term follow-up study of 3931 patients
    • Chaparro M, Ordas I, Cabre E, Garcia-Sanchez V, Bastida G, Penalva M, et al. Safety of thiopurine therapy in inflammatory bowel disease: long-term follow-up study of 3931 patients. Inflamm Bowel Dis 2013;19:1404-10.
    • (2013) Inflamm Bowel Dis , vol.19 , pp. 1404-1410
    • Chaparro, M.1    Ordas, I.2    Cabre, E.3    Garcia-Sanchez, V.4    Bastida, G.5    Penalva, M.6
  • 137
    • 84886267819 scopus 로고    scopus 로고
    • Risk of lymphoma in patients with ulcerative colitis treated with thiopurines: A nationwide retrospective cohort study
    • Khan N, Abbas AM, Lichtenstein GR, Loftus EV Jr, Bazzano LA. Risk of lymphoma in patients with ulcerative colitis treated with thiopurines: a nationwide retrospective cohort study. Gastroenterology 2013;145:1007-15.e3.
    • (2013) Gastroenterology , vol.145 , pp. 1007-1007e3
    • Khan, N.1    Abbas, A.M.2    Lichtenstein, G.R.3    Loftus, E.V.4    Bazzano, L.A.5
  • 138
    • 78650239266 scopus 로고    scopus 로고
    • A systematic review of factors that contribute to hepatosplenic T-cell lymphoma in patients with inflammatory bowel disease
    • Kotlyar DS, Osterman MT, Diamond RH, Porter D, Blonski WC, Wasik M, et al. A systematic review of factors that contribute to hepatosplenic T-cell lymphoma in patients with inflammatory bowel disease. Clin Gastroen-terol Hepatol 2011;9:36-41.e1.
    • (2011) Clin Gastroen-terol Hepatol , vol.9 , pp. 36-36e1
    • Kotlyar, D.S.1    Osterman, M.T.2    Diamond, R.H.3    Porter, D.4    Blonski, W.C.5    Wasik, M.6
  • 139
    • 84885955210 scopus 로고    scopus 로고
    • A trial of mercaptopurine is a safe strategy in patients with inflammatory bowel disease intolerant to azathioprine: An observational study, systematic review and meta-analysis
    • Kennedy NA, Rhatigan E, Arnott ID, Noble CL, Shand AG, Satsangi J, et al. A trial of mercaptopurine is a safe strategy in patients with inflammatory bowel disease intolerant to azathioprine: an observational study, systematic review and meta-analysis. Aliment Pharmacol Ther 2013;38:1255-66.
    • (2013) Aliment Pharmacol Ther , vol.38 , pp. 1255-1266
    • Kennedy, N.A.1    Rhatigan, E.2    Arnott, I.D.3    Noble, C.L.4    Shand, A.G.5    Satsangi, J.6
  • 141
    • 0030954732 scopus 로고    scopus 로고
    • A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease. Crohn's Disease cA2 Study Group
    • Targan SR, Hanauer SB, van Deventer SJ, Mayer L, Present DH, Braakman T, et al. A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease. Crohn's Disease cA2 Study Group. N Engl J Med 1997;337:1029-35.
    • (1997) N Engl J Med , vol.337 , pp. 1029-1035
    • Targan, S.R.1    Hanauer, S.B.2    Van Deventer, S.J.3    Mayer, L.4    Present, D.H.5    Braakman, T.6
  • 142
    • 32044451548 scopus 로고    scopus 로고
    • Human anti-tumor necrosis factor monoclonal antibody (adalimumab) in Crohn's disease: The CLASSIC-I trial
    • quiz 591
    • Hanauer SB, Sandborn WJ, Rutgeerts P, Fedorak RN, Lukas M, MacIntosh D, et al. Human anti-tumor necrosis factor monoclonal antibody (adalimumab) in Crohn's disease: the CLASSIC-I trial. Gastroenterology 2006;130: 323-33; quiz 591.
    • (2006) Gastroenterology , vol.130 , pp. 323-333
    • Hanauer, S.B.1    Sandborn, W.J.2    Rutgeerts, P.3    Fedorak, R.N.4    Lukas, M.5    MacIntosh, D.6
  • 144
    • 70349418632 scopus 로고    scopus 로고
    • Colectomy rate comparison after treatment of ulcerative colitis with placebo or infliximab
    • quiz 520
    • Sandborn WJ, Rutgeerts P, Feagan BG, Reinisch W, Olson A, Johanns J, et al. Colectomy rate comparison after treatment of ulcerative colitis with placebo or infliximab. Gastroenterology 2009;137:1250-60; quiz 520.
    • (2009) Gastroenterology , vol.137 , pp. 1250-1260
    • Sandborn, W.J.1    Rutgeerts, P.2    Feagan, B.G.3    Reinisch, W.4    Olson, A.5    Johanns, J.6
  • 145
    • 33750105599 scopus 로고    scopus 로고
    • Tumour necrosis factor alpha blocking agents for induction of remission in ulcerative colitis
    • Lawson MM, Thomas AG, Akobeng AK. Tumour necrosis factor alpha blocking agents for induction of remission in ulcerative colitis. Cochrane Database Syst Rev 2006: CD005112.
    • (2006) Cochrane Database Syst Rev , pp. CD005112
    • Lawson, M.M.1    Thomas, A.G.2    Akobeng, A.K.3
  • 148
    • 63849101007 scopus 로고    scopus 로고
    • Long-term outcome of treatment with infliximab in 614 patients with Crohn's disease: Results from a single-centre cohort
    • Schnitzler F, Fidder H, Ferrante M, Noman M, Arijs I, Van Assche G, et al. Long-term outcome of treatment with infliximab in 614 patients with Crohn's disease: results from a single-centre cohort. Gut 2009;58:492-500.
    • (2009) Gut , vol.58 , pp. 492-500
    • Schnitzler, F.1    Fidder, H.2    Ferrante, M.3    Noman, M.4    Arijs, I.5    Van Assche, G.6
  • 150
    • 84892979466 scopus 로고    scopus 로고
    • Postinduction serum infliximab trough level and decrease of C-reactive protein level are associated with durable sustained response to infliximab: A retrospective analysis of the ACCENT i trial
    • Epub ahead of print
    • Cornillie F, Hanauer SB, Diamond RH, Wang J, Tang KL, Xu Z, et al. Postinduction serum infliximab trough level and decrease of C-reactive protein level are associated with durable sustained response to infliximab: a retrospective analysis of the ACCENT I trial. Gut 2014;Epub ahead of print.
    • (2014) Gut
    • Cornillie, F.1    Hanauer, S.B.2    Diamond, R.H.3    Wang, J.4    Tang, K.L.5    Xu, Z.6
  • 151
    • 44849131569 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha antibody for maintenance of remission in Crohn's disease
    • Behm BW, Bickston SJ. Tumor necrosis factor-alpha antibody for maintenance of remission in Crohn's disease. Cochrane Database Syst Rev 2008:CD006893.
    • (2008) Cochrane Database Syst Rev , pp. CD006893
    • Behm, B.W.1    Bickston, S.J.2
  • 152
    • 79955859430 scopus 로고    scopus 로고
    • Adalimumab for induction of clinical remission in moderately to severely active ulcerative colitis: Results of a randomised controlled trial
    • Reinisch W, Sandborn WJ, Hommes DW, D'Haens G, Hanauer S, Schreiber S, et al. Adalimumab for induction of clinical remission in moderately to severely active ulcerative colitis: results of a randomised controlled trial. Gut 2011; 60:780-7.
    • (2011) Gut , vol.60 , pp. 780-787
    • Reinisch, W.1    Sandborn, W.J.2    Hommes, D.W.3    D'Haens, G.4    Hanauer, S.5    Schreiber, S.6
  • 153
    • 84856163835 scopus 로고    scopus 로고
    • Adalimumab induces and maintains clinical remission in patients with moderate-to-severe ulcerative colitis
    • e1-3
    • Sandborn WJ, van Assche G, Reinisch W, Colombel JF, D'Haens G, Wolf DC, et al. Adalimumab induces and maintains clinical remission in patients with moderate-to-severe ulcerative colitis. Gastroenterology 2012;142:257-65; e1-3.
    • (2012) Gastroenterology , vol.142 , pp. 257-265
    • Sandborn, W.J.1    Van Assche, G.2    Reinisch, W.3    Colombel, J.F.4    D'Haens, G.5    Wolf, D.C.6
  • 154
    • 84872832486 scopus 로고    scopus 로고
    • One-year maintenance outcomes among patients with moderately-to-severely active ulcera-tive colitis who responded to induction therapy with ada-limumab: Subgroup analyses from ULTRA 2
    • Sandborn WJ, Colombel JF, D'Haens G, Van Assche G, Wolf D, Kron M, et al. One-year maintenance outcomes among patients with moderately-to-severely active ulcera-tive colitis who responded to induction therapy with ada-limumab: subgroup analyses from ULTRA 2. Aliment Pharmacol Ther 2013;37:204-13.
    • (2013) Aliment Pharmacol Ther , vol.37 , pp. 204-213
    • Sandborn, W.J.1    Colombel, J.F.2    D'Haens, G.3    Van Assche, G.4    Wolf, D.5    Kron, M.6
  • 155
    • 84890688226 scopus 로고    scopus 로고
    • Adalimumab therapy is associated with reduced risk of hospitalization in patients with ulcerative colitis
    • Feagan BG, Sandborn WJ, Lazar A, Thakkar RB, Huang B, Reilly N, et al. Adalimumab therapy is associated with reduced risk of hospitalization in patients with ulcerative colitis. Gastroenterology 2014;146:110-8.e3.
    • (2014) Gastroenterology , vol.146 , pp. 110-110e3
    • Feagan, B.G.1    Sandborn, W.J.2    Lazar, A.3    Thakkar, R.B.4    Huang, B.5    Reilly, N.6
  • 156
    • 84862777782 scopus 로고    scopus 로고
    • Adalimumab induces and maintains mucosal healing in patients with Crohn's disease: Data from the EXTEND trial
    • Rutgeerts P, Van Assche G, Sandborn WJ, Wolf DC, Geboes K, Colombel JF, et al. Adalimumab induces and maintains mucosal healing in patients with Crohn's disease: data from the EXTEND trial. Gastroenterology 2012;142: 1102-11.e2.
    • (2012) Gastroenterology , vol.142 , pp. 1102-1102e2
    • Rutgeerts, P.1    Van Assche, G.2    Sandborn, W.J.3    Wolf, D.C.4    Geboes, K.5    Colombel, J.F.6
  • 157
    • 34249281002 scopus 로고    scopus 로고
    • Adalimumab for maintenance treatment of Crohn's disease: Results of the CLASSIC II trial
    • Sandborn WJ, Hanauer SB, Rutgeerts P, Fedorak RN, Lukas M, MacIntosh DG, et al. Adalimumab for maintenance treatment of Crohn's disease: results of the CLASSIC II trial. Gut 2007;56:1232-9.
    • (2007) Gut , vol.56 , pp. 1232-1239
    • Sandborn, W.J.1    Hanauer, S.B.2    Rutgeerts, P.3    Fedorak, R.N.4    Lukas, M.5    MacIntosh, D.G.6
  • 158
    • 33846242958 scopus 로고    scopus 로고
    • Adalimumab for maintenance of clinical response and remission in patients with Crohn's disease: The CHARM trial
    • Colombel JF, Sandborn WJ, Rutgeerts P, Enns R, Hanauer SB, Panaccione R, et al. Adalimumab for maintenance of clinical response and remission in patients with Crohn's disease: the CHARM trial. Gastroenterology 2007; 132:52-65.
    • (2007) Gastroenterology , vol.132 , pp. 52-65
    • Colombel, J.F.1    Sandborn, W.J.2    Rutgeerts, P.3    Enns, R.4    Hanauer, S.B.5    Panaccione, R.6
  • 159
    • 84885956038 scopus 로고    scopus 로고
    • Adalimumab maintains remission of Crohn's disease after up to 4 years of treatment: Data from CHARM and ADHERE
    • Panaccione R, Colombel JF, Sandborn WJ, D'Haens G, Zhou Q, Pollack PF, et al. Adalimumab maintains remission of Crohn's disease after up to 4 years of treatment: data from CHARM and ADHERE. Aliment Pharmacol Ther 2013;38:1236-47.
    • (2013) Aliment Pharmacol Ther , vol.38 , pp. 1236-1247
    • Panaccione, R.1    Colombel, J.F.2    Sandborn, W.J.3    D'Haens, G.4    Zhou, Q.5    Pollack, P.F.6
  • 160
    • 39449085441 scopus 로고    scopus 로고
    • Early combined immuno-suppression or conventional management in patients with newly diagnosed Crohn's disease: An open randomised trial
    • D'Haens G, Baert F, van Assche G, Caenepeel P, Vergauwe P, Tuynman H, et al. Early combined immuno-suppression or conventional management in patients with newly diagnosed Crohn's disease: an open randomised trial. Lancet 2008;371:660-7.
    • (2008) Lancet , vol.371 , pp. 660-667
    • D'Haens, G.1    Baert, F.2    Van Assche, G.3    Caenepeel, P.4    Vergauwe, P.5    Tuynman, H.6
  • 161
    • 84903853083 scopus 로고    scopus 로고
    • Early combined immunosuppression for the management of Crohn's disease: A community-based cluster randomized trial
    • Khanna R, Levesque B, Bressler B, Zou G, Stitt L, Greenberg GR, et al. Early combined immunosuppression for the management of Crohn's disease: a community-based cluster randomized trial. J Crohns Colitis 2014;8:S2-3.
    • (2014) J Crohns Colitis , vol.8 , pp. S2-3
    • Khanna, R.1    Levesque, B.2    Bressler, B.3    Zou, G.4    Stitt, L.5    Greenberg, G.R.6
  • 163
    • 84894302120 scopus 로고    scopus 로고
    • Methotrexate in combination with infliximab is no more effective than infliximab alone in patients with Crohn's disease
    • Feagan BG, McDonald JW, Panaccione R, Enns RA, Bernstein CN, Ponich TP, et al. Methotrexate in combination with infliximab is no more effective than infliximab alone in patients with Crohn's disease. Gastroenterology 2014;146:681-8.e1.
    • (2014) Gastroenterology , vol.146 , pp. 681-681e1
    • Feagan, B.G.1    McDonald, J.W.2    Panaccione, R.3    Enns, R.A.4    Bernstein, C.N.5    Ponich, T.P.6
  • 164
    • 84892737455 scopus 로고    scopus 로고
    • Combination therapy with inflix-imab and azathioprine is superior to monotherapy with either agent in ulcerative colitis
    • Panaccione R, Ghosh S, Middleton S, Marquez JR, Scott BB, Flint L, et al. Combination therapy with inflix-imab and azathioprine is superior to monotherapy with either agent in ulcerative colitis. Gastroenterology 2014; 146:392-400.e3.
    • (2014) Gastroenterology , vol.146 , pp. 392-392e3
    • Panaccione, R.1    Ghosh, S.2    Middleton, S.3    Marquez, J.R.4    Scott, B.B.5    Flint, L.6
  • 165
    • 0347991877 scopus 로고    scopus 로고
    • The safety profile of inflix-imab in patients with Crohn's disease: The Mayo clinic experience in 500 patients
    • Colombel JF, Loftus EV Jr, Tremaine WJ, Egan LJ, Harmsen WS, Schleck CD, et al. The safety profile of inflix-imab in patients with Crohn's disease: the Mayo clinic experience in 500 patients. Gastroenterology 2004;126:19-31.
    • (2004) Gastroenterology , vol.126 , pp. 19-31
    • Colombel, J.F.1    Loftus, E.V.2    Tremaine, W.J.3    Egan, L.J.4    Harmsen, W.S.5    Schleck, C.D.6
  • 166
    • 0028271186 scopus 로고
    • A placebo-controlled trial of cyclosporine enemas formildlytomoderately active left-sided ulcerative colitis
    • Sandborn WJ, Tremaine WJ, Schroeder KW, Batts KP, Lawson GM, Steiner BL, et al. A placebo-controlled trial of cyclosporine enemas formildlytomoderately active left-sided ulcerative colitis. Gastroenterology 1994;106:1429-35.
    • (1994) Gastroenterology , vol.106 , pp. 1429-1435
    • Sandborn, W.J.1    Tremaine, W.J.2    Schroeder, K.W.3    Batts, K.P.4    Lawson, G.M.5    Steiner, B.L.6
  • 167
    • 0024429141 scopus 로고
    • A placebo-controlled, double-blind, randomized trial of cyclosporine therapy in active chronic Crohn's disease
    • Brynskov J, Freund L, Rasmussen SN, Lauritsen K, de Muckadell OS, Williams N, et al. A placebo-controlled, double-blind, randomized trial of cyclosporine therapy in active chronic Crohn's disease. N Engl J Med 1989;321: 845-50.
    • (1989) N Engl J Med , vol.321 , pp. 845-850
    • Brynskov, J.1    Freund, L.2    Rasmussen, S.N.3    Lauritsen, K.4    De Muckadell, O.S.5    Williams, N.6
  • 169
    • 84859801314 scopus 로고    scopus 로고
    • Double-blind, placebo-controlled trial of oral tacrolimus (FK506) in the management of hospitalized patients with steroid-refractory ulcerative colitis
    • Ogata H, Kato J, Hirai F, Hida N, Matsui T, Matsumoto T, et al. Double-blind, placebo-controlled trial of oral tacrolimus (FK506) in the management of hospitalized patients with steroid-refractory ulcerative colitis. Inflamm Bowel Dis 2012;18:803-8.
    • (2012) Inflamm Bowel Dis , vol.18 , pp. 803-808
    • Ogata, H.1    Kato, J.2    Hirai, F.3    Hida, N.4    Matsui, T.5    Matsumoto, T.6
  • 170
    • 33747790601 scopus 로고    scopus 로고
    • A randomised dose finding study of oral tacrolimus (FK506) therapy in refractory ulcerative colitis
    • Ogata H, Matsui T, Nakamura M, Iida M, Takazoe M, Suzuki Y, et al. A randomised dose finding study of oral tacrolimus (FK506) therapy in refractory ulcerative colitis. Gut 2006;55:1255-62.
    • (2006) Gut , vol.55 , pp. 1255-1262
    • Ogata, H.1    Matsui, T.2    Nakamura, M.3    Iida, M.4    Takazoe, M.5    Suzuki, Y.6
  • 171
    • 54049121762 scopus 로고    scopus 로고
    • Rectal tacrolimus in the treatment of resistant ulcerative proctitis
    • Lawrance IC, Copeland TS. Rectal tacrolimus in the treatment of resistant ulcerative proctitis. Aliment Pharmacol Ther 2008;28:1214-20.
    • (2008) Aliment Pharmacol Ther , vol.28 , pp. 1214-1220
    • Lawrance, I.C.1    Copeland, T.S.2
  • 172
    • 81355160293 scopus 로고    scopus 로고
    • Systematic review: The role of tacrolimus in the management of Crohn's disease
    • McSharry K, Dalzell AM, Leiper K, El-Matary W. Systematic review: the role of tacrolimus in the management of Crohn's disease. Aliment Pharmacol Ther 2011;34: 1282-94.
    • (2011) Aliment Pharmacol Ther , vol.34 , pp. 1282-1294
    • McSharry, K.1    Dalzell, A.M.2    Leiper, K.3    El-Matary, W.4
  • 173
    • 1542619846 scopus 로고    scopus 로고
    • Long-term outcome of treatment with intravenous cyclosporin in patients with severe ulcerative colitis
    • Arts J, D'Haens G, Zeegers M, Van Assche G, Hiele M, D'Hoore A, et al. Long-term outcome of treatment with intravenous cyclosporin in patients with severe ulcerative colitis. Inflamm Bowel Dis 2004;10:73-8.
    • (2004) Inflamm Bowel Dis , vol.10 , pp. 73-78
    • Arts, J.1    D'Haens, G.2    Zeegers, M.3    Van Assche, G.4    Hiele, M.5    D'Hoore, A.6
  • 174
    • 77955428694 scopus 로고    scopus 로고
    • Newly developed antibiotic combination therapy for ulcerative colitis: A double-blind placebo-controlled multicenter trial
    • Ohkusa T, Kato K, Terao S, Chiba T, Mabe K, Murakami K, et al. Newly developed antibiotic combination therapy for ulcerative colitis: a double-blind placebo-controlled multicenter trial. Am J Gastroenterol 2010;105: 1820-9.
    • (2010) Am J Gastroenterol , vol.105 , pp. 1820-1829
    • Ohkusa, T.1    Kato, K.2    Terao, S.3    Chiba, T.4    Mabe, K.5    Murakami, K.6
  • 177
    • 33846252777 scopus 로고    scopus 로고
    • Response to corticosteroids in severe ulcerative colitis: A systematic review of the literature and a meta-regression
    • Turner D, Walsh CM, Steinhart AH, Griffiths AM. Response to corticosteroids in severe ulcerative colitis: a systematic review of the literature and a meta-regression. Clin Gastroenterol Hepatol 2007;5:103-10.
    • (2007) Clin Gastroenterol Hepatol , vol.5 , pp. 103-110
    • Turner, D.1    Walsh, C.M.2    Steinhart, A.H.3    Griffiths, A.M.4
  • 178
    • 78651235878 scopus 로고    scopus 로고
    • Predicting the need for colectomy in severe ulcerative colitis: A critical appraisal of clinical parameters and currently available biomarkers
    • Travis S, Satsangi J, Lemann M. Predicting the need for colectomy in severe ulcerative colitis: a critical appraisal of clinical parameters and currently available biomarkers. Gut 2011;60:3-9.
    • (2011) Gut , vol.60 , pp. 3-9
    • Travis, S.1    Satsangi, J.2    Lemann, M.3
  • 179
    • 10744231879 scopus 로고    scopus 로고
    • Randomized, double-blind comparison of 4 mg/kg versus 2 mg/kg intravenous cyclo-sporine in severe ulcerative colitis
    • Van Assche G, D'Haens G, Noman M, Vermeire S, Hiele M, Asnong K, et al. Randomized, double-blind comparison of 4 mg/kg versus 2 mg/kg intravenous cyclo-sporine in severe ulcerative colitis. Gastroenterology 2003; 125:1025-31.
    • (2003) Gastroenterology , vol.125 , pp. 1025-1031
    • Van Assche, G.1    D'Haens, G.2    Noman, M.3    Vermeire, S.4    Hiele, M.5    Asnong, K.6
  • 180
    • 20444479336 scopus 로고    scopus 로고
    • Infliximab as rescue therapy in severe to moderately severe ulcerative colitis: A randomized, placebo-controlled study
    • Jarnerot G, Hertervig E, Friis-Liby I, Blomquist L, Karlen P, Granno C, et al. Infliximab as rescue therapy in severe to moderately severe ulcerative colitis: a randomized, placebo-controlled study. Gastroenterology 2005;128:1805-11.
    • (2005) Gastroenterology , vol.128 , pp. 1805-1811
    • Jarnerot, G.1    Hertervig, E.2    Friis-Liby, I.3    Blomquist, L.4    Karlen, P.5    Granno, C.6
  • 181
    • 84870293844 scopus 로고    scopus 로고
    • Ciclosporin versus infliximab in patients with severe ulcerative colitis refractory to intravenous steroids: A parallel, open-label randomised controlled trial
    • Laharie D, Bourreille A, Branche J, Allez M, Bouhnik Y, Filippi J, et al. Ciclosporin versus infliximab in patients with severe ulcerative colitis refractory to intravenous steroids: a parallel, open-label randomised controlled trial. Lancet 2012;380:1909-15.
    • (2012) Lancet , vol.380 , pp. 1909-1915
    • Laharie, D.1    Bourreille, A.2    Branche, J.3    Allez, M.4    Bouhnik, Y.5    Filippi, J.6
  • 182
    • 84893655716 scopus 로고    scopus 로고
    • Rescue therapy with cyclosporine or infliximab is not associated with an increased risk for postoperative complications in patients hospitalized for severe steroid-refractory ulcerative colitis
    • Nelson R, Liao C, Fichera A, Rubin DT, Pekow J. Rescue therapy with cyclosporine or infliximab is not associated with an increased risk for postoperative complications in patients hospitalized for severe steroid-refractory ulcerative colitis. Inflamm Bowel Dis 2014;20:14-20.
    • (2014) Inflamm Bowel Dis , vol.20 , pp. 14-20
    • Nelson, R.1    Liao, C.2    Fichera, A.3    Rubin, D.T.4    Pekow, J.5
  • 183
    • 84964948229 scopus 로고    scopus 로고
    • Infliximab or ciclosporin: Patients treatment preferences and the impact of ulcerative colitis (UC) on their lives
    • Seagrove A, Williams J. Infliximab or ciclosporin: patients treatment preferences and the impact of ulcerative colitis (UC) on their lives. Gut 2014;63:A65.
    • (2014) Gut , vol.63 , pp. A65
    • Seagrove, A.1    Williams, J.2
  • 184
    • 0018903830 scopus 로고
    • Occurrence and outcome after primary treatment of anal fistulae in Crohn's disease
    • Hellers G, Bergstrand O, Ewerth S, Holmstrom B. Occurrence and outcome after primary treatment of anal fistulae in Crohn's disease. Gut 1980;21:525-7.
    • (1980) Gut , vol.21 , pp. 525-527
    • Hellers, G.1    Bergstrand, O.2    Ewerth, S.3    Holmstrom, B.4
  • 185
    • 61949132271 scopus 로고    scopus 로고
    • Ciprofloxacin or metronidazole for the treatment of perianal fistulas in patients with Crohn's disease: A randomized, double-blind, placebo-controlled pilot study
    • Thia KT, Mahadevan U, Feagan BG, Wong C, Cockeram A, Bitton A, et al. Ciprofloxacin or metronidazole for the treatment of perianal fistulas in patients with Crohn's disease: a randomized, double-blind, placebo-controlled pilot study. Inflamm Bowel Dis 2009;15:17-24.
    • (2009) Inflamm Bowel Dis , vol.15 , pp. 17-24
    • Thia, K.T.1    Mahadevan, U.2    Feagan, B.G.3    Wong, C.4    Cockeram, A.5    Bitton, A.6
  • 186
    • 84891748257 scopus 로고    scopus 로고
    • Adalimumab combined with ciprofloxacin is superior to adalimumab monotherapy in perianal fistula closure in Crohn's disease: A randomised, double-blind, placebo controlled trial (ADAFI)
    • Dewint P, Hansen BE, Verhey E, Oldenburg B, Hommes DW, Pierik M, et al. Adalimumab combined with ciprofloxacin is superior to adalimumab monotherapy in perianal fistula closure in Crohn's disease: a randomised, double-blind, placebo controlled trial (ADAFI). Gut 2014; 63:292-9.
    • (2014) Gut , vol.63 , pp. 292-299
    • Dewint, P.1    Hansen, B.E.2    Verhey, E.3    Oldenburg, B.4    Hommes, D.W.5    Pierik, M.6
  • 187
    • 11144346129 scopus 로고    scopus 로고
    • Clinical and endosono-graphic effect of ciprofloxacin on the treatment of perianal fistulae in Crohn's disease with infliximab: A double-blind placebo-controlled study
    • West RL, van der Woude CJ, Hansen BE, Felt-Bersma RJ, van Tilburg AJ, Drapers JA, et al. Clinical and endosono-graphic effect of ciprofloxacin on the treatment of perianal fistulae in Crohn's disease with infliximab: a double-blind placebo-controlled study. Aliment Pharmacol Ther 2004; 20:1329-36.
    • (2004) Aliment Pharmacol Ther , vol.20 , pp. 1329-1336
    • West, R.L.1    Van Der Woude, C.J.2    Hansen, B.E.3    Felt-Bersma, R.J.4    Van Tilburg, A.J.5    Drapers, J.A.6
  • 188
    • 0029134702 scopus 로고
    • Azathi-oprine and 6-mercaptopurine in Crohn disease. A meta-analysis
    • Pearson DC, May GR, Fick GH, Sutherland LR. Azathi-oprine and 6-mercaptopurine in Crohn disease. A meta-analysis. Ann Intern Med 1995;123:132-42.
    • (1995) Ann Intern Med , vol.123 , pp. 132-142
    • Pearson, D.C.1    May, G.R.2    Fick, G.H.3    Sutherland, L.R.4
  • 191
    • 5044235159 scopus 로고    scopus 로고
    • Long-term treatment of rectovaginal fistulas in Crohn's disease: Response to infliximab in the ACCENT II Study
    • Sands BE, Blank MA, Patel K, van Deventer SJ. Long-term treatment of rectovaginal fistulas in Crohn's disease: response to infliximab in the ACCENT II Study. Clin Gastroenterol Hepatol 2004;2:912-20.
    • (2004) Clin Gastroenterol Hepatol , vol.2 , pp. 912-920
    • Sands, B.E.1    Blank, M.A.2    Patel, K.3    Van Deventer, S.J.4
  • 193
    • 78249282645 scopus 로고    scopus 로고
    • The CHOICE trial: Adalimu-mab demonstrates safety, fistula healing, improved quality of life and increased work productivity in patients with Crohn's disease who failed prior infliximab therapy
    • Lichtiger S, Binion DG, Wolf DC, Present DH, Bensimon AG, Wu E, et al. The CHOICE trial: adalimu-mab demonstrates safety, fistula healing, improved quality of life and increased work productivity in patients with Crohn's disease who failed prior infliximab therapy. Aliment Pharmacol Ther 2010;32:1228-39.
    • (2010) Aliment Pharmacol Ther , vol.32 , pp. 1228-1239
    • Lichtiger, S.1    Binion, D.G.2    Wolf, D.C.3    Present, D.H.4    Bensimon, A.G.5    Wu, E.6
  • 194
    • 0037245392 scopus 로고    scopus 로고
    • Medication non-adherence and the outcomes of patients with quiescent ulcerative colitis
    • Kane S, Huo D, Aikens J, Hanauer S. Medication non-adherence and the outcomes of patients with quiescent ulcerative colitis. Am J Med 2003;114:39-43.
    • (2003) Am J Med , vol.114 , pp. 39-43
    • Kane, S.1    Huo, D.2    Aikens, J.3    Hanauer, S.4
  • 195
    • 33846820178 scopus 로고    scopus 로고
    • Effect of allopurinol on clinical outcomes in inflammatory bowel disease nonresponders to azathioprine or 6-mercap-topurine
    • Sparrow MP, Hande SA, Friedman S, Cao D, Hanauer SB. Effect of allopurinol on clinical outcomes in inflammatory bowel disease nonresponders to azathioprine or 6-mercap-topurine. Clin Gastroenterol Hepatol 2007;5:209-14.
    • (2007) Clin Gastroenterol Hepatol , vol.5 , pp. 209-214
    • Sparrow, M.P.1    Hande, S.A.2    Friedman, S.3    Cao, D.4    Hanauer, S.B.5
  • 196
    • 62049083383 scopus 로고    scopus 로고
    • Loss of response and requirement of infliximab dose intensification in Crohn's disease: A review
    • Gisbert JP, Panes J. Loss of response and requirement of infliximab dose intensification in Crohn's disease: a review. Am J Gastroenterol 2009;104:760-7.
    • (2009) Am J Gastroenterol , vol.104 , pp. 760-767
    • Gisbert, J.P.1    Panes, J.2
  • 198
    • 84882454346 scopus 로고    scopus 로고
    • Review article: A clinician's guide for therapeutic drug monitoring of infliximab in inflammatory bowel disease
    • Khanna R, Sattin BD, Afif W, Benchimol EI, Bernard EJ, Bitton A, et al. Review article: a clinician's guide for therapeutic drug monitoring of infliximab in inflammatory bowel disease. Aliment Pharmacol Ther 2013;38:447-59.
    • (2013) Aliment Pharmacol Ther , vol.38 , pp. 447-459
    • Khanna, R.1    Sattin, B.D.2    Afif, W.3    Benchimol, E.I.4    Bernard, E.J.5    Bitton, A.6
  • 199
    • 34347402306 scopus 로고    scopus 로고
    • Adalimumab induction therapy for Crohn disease previously treated with infliximab: A randomized trial
    • Sandborn WJ, Rutgeerts P, Enns R, Hanauer SB, Colombel JF, Panaccione R, et al. Adalimumab induction therapy for Crohn disease previously treated with infliximab: a randomized trial. Ann Intern Med 2007;146:829-38.
    • (2007) Ann Intern Med , vol.146 , pp. 829-838
    • Sandborn, W.J.1    Rutgeerts, P.2    Enns, R.3    Hanauer, S.B.4    Colombel, J.F.5    Panaccione, R.6
  • 203
    • 79952267166 scopus 로고    scopus 로고
    • Oral 5-aminosalicylic acid for maintenance of surgically-induced remission in Crohn's disease
    • Gordon M, Naidoo K, Thomas AG, Akobeng AK. Oral 5-aminosalicylic acid for maintenance of surgically-induced remission in Crohn's disease. Cochrane Database Syst Rev 2011:CD008414.
    • (2011) Cochrane Database Syst Rev , pp. CD008414
    • Gordon, M.1    Naidoo, K.2    Thomas, A.G.3    Akobeng, A.K.4
  • 205
  • 206
    • 84887237442 scopus 로고    scopus 로고
    • Adalimumab is more effective than azathioprine and mesalamine at preventing postoperative recurrence of Crohn's disease: A randomized controlled trial
    • Savarino E, Bodini G, Dulbecco P, Assandri L, Bruzzone L, Mazza F, et al. Adalimumab is more effective than azathioprine and mesalamine at preventing postoperative recurrence of Crohn's disease: a randomized controlled trial. Am J Gastroenterol 2013;108:1731-42.
    • (2013) Am J Gastroenterol , vol.108 , pp. 1731-1742
    • Savarino, E.1    Bodini, G.2    Dulbecco, P.3    Assandri, L.4    Bruzzone, L.5    Mazza, F.6
  • 207
    • 84906718973 scopus 로고    scopus 로고
    • Optimising post-operative Crohn's disease management: Best drug therapy alone versus endoscopic monitoring, disease evolution, and faecal calprotectin monitoring. The POCER study
    • Kamm MA, De Cruz P, Wright EK, Hamilton AL, Ritchie KJ, Krejany EO, et al. Optimising post-operative Crohn's disease management: best drug therapy alone versus endoscopic monitoring, disease evolution, and faecal calprotectin monitoring. The POCER study. J Crohn's Colitis 2014;8:S13.
    • (2014) J Crohn's Colitis , vol.8 , pp. S13
    • Kamm, M.A.1    De Cruz, P.2    Wright, E.K.3    Hamilton, A.L.4    Ritchie, K.J.5    Krejany, E.O.6
  • 208
    • 84904425206 scopus 로고    scopus 로고
    • Review article: Why, when and how to de-escalate therapy in inflammatory bowel diseases
    • Pariente B, Laharie D. Review article: why, when and how to de-escalate therapy in inflammatory bowel diseases. Aliment Pharmacol Ther 2014;40:338-53.
    • (2014) Aliment Pharmacol Ther , vol.40 , pp. 338-353
    • Pariente, B.1    Laharie, D.2
  • 209
    • 44649090092 scopus 로고    scopus 로고
    • Withdrawal of immunosuppression in Crohn's disease treated with scheduled infliximab maintenance: A randomized trial
    • Van Assche G, Magdelaine-Beuzelin C, D'Haens G, Baert F, Noman M, Vermeire S, et al. Withdrawal of immunosuppression in Crohn's disease treated with scheduled infliximab maintenance: a randomized trial. Gastro-enterology 2008;134:1861-8.
    • (2008) Gastro-enterology , vol.134 , pp. 1861-1868
    • Van Assche, G.1    Magdelaine-Beuzelin, C.2    D'Haens, G.3    Baert, F.4    Noman, M.5    Vermeire, S.6
  • 210
    • 83955162272 scopus 로고    scopus 로고
    • Maintenance of remission among patients with Crohn's disease on antimetabolite therapy after infliximab therapy is stopped
    • quiz e31
    • Louis E, Mary JY, Vernier-Massouille G, Grimaud JC, Bouhnik Y, Laharie D, et al. Maintenance of remission among patients with Crohn's disease on antimetabolite therapy after infliximab therapy is stopped. Gastroenterol-ogy 2012;142:63-70.e5; quiz e31.
    • (2012) Gastroenterol-ogy , vol.142 , pp. 63-63e5
    • Louis, E.1    Mary, J.Y.2    Vernier-Massouille, G.3    Grimaud, J.C.4    Bouhnik, Y.5    Laharie, D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.