Long-term treatment of rectovaginal fistulas in Crohn's disease: Response to infliximab in the ACCENT II study

Clinical Gastroenterology and Hepatology

Volumn 2, Issue 10, 2004, Pages 912-920

  Sands, Bruce E ^a   Blank, Marion A ^b   Patel, Kam ^b   Van Deventer, Sander J ^c  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b CENTOCOR INC   (United States)

^c ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; CORTICOSTEROID; INFLIXIMAB; METRONIDAZOLE; PLACEBO;

ABDOMINAL PAIN; ABSCESS; ABSCESS DRAINAGE; ADULT; ARTHRALGIA; ARTICLE; CLINICAL TRIAL; COLON CROHN DISEASE; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DATA ANALYSIS; DISEASE DURATION; DISEASE EXACERBATION; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG HYPERSENSITIVITY; DRUG INFUSION; DRUG SAFETY; FATIGUE; FEMALE; GASTROINTESTINAL TOXICITY; HEADACHE; HUMAN; MAJOR CLINICAL STUDY; NAUSEA; NEPHROLITHIASIS; PERIANAL ABSCESS; RANDOMIZED CONTROLLED TRIAL; RECTOVAGINAL FISTULA; SHORT COURSE THERAPY; UPPER RESPIRATORY TRACT INFECTION;

ABDOMINAL ABSCESS; ABDOMINAL PAIN; ADULT; ANTIBODIES, MONOCLONAL; ARTHRALGIA; CROHN DISEASE; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; DRUG ADMINISTRATION SCHEDULE; FEMALE; GASTROINTESTINAL AGENTS; HEADACHE; HUMANS; INFUSIONS, INTRAVENOUS; NAUSEA; QUALITY OF LIFE; RECTOVAGINAL FISTULA; RESPIRATORY TRACT INFECTIONS;

EID: 5044235159     PISSN: 15423565     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1542-3565(04)00414-8     Document Type: Article

References (20)

1. C. Levy, W.J. Tremaine Management of internal fistulas in Crohn's disease Inflamm Bowel Dis 8 2002 106 111
2. D.A. Schwartz, E.V. Loftus, W.J. Tremaine, R. Panaccione, W.S. Harmsen, A.R. Zinsmeister, W.J. Sandborn The natural history of fistulizing Crohn's disease in Olmsted County, Minnesota Gastroenterology 122 2002 875 880
3. W.J. Sandborn, V.W. Fazio, B.G. Feagan, S.B. Hanauer AGA technical review on perianal Crohn's disease Gastroenterology 125 2003 1508 1530
4. T. Hull Rectovaginal fistulae T. Bayless S. Hanauer Advanced therapy of inflammatory bowel disease 2001 B.C. Decker Inc Hamilton, Canada 515 518
5. O.M. Jones, N.J.M. Mortensen Surgical treatment of Crohn's disease J. Satsangi L.R. Sutherland J.F. Colombel C. Fiocchi R. Lofberg J.H. Pemberton P. Rutgeerts Inflammatory bowel diseases 2003 Churchill Livingstone, Elsevier Limited London, UK 513 538
6. D.H. Present Inflammatory bowel disease workshop. Vail, Colorado, March 22 and 23, 1998. Management of fistula disease Inflamm Bowel Dis 4 1998 302 307
7. D.H. Present, P. Rutgeerts, S. Targan, S.B. Hanauer, L. Mayer, R.A. van Hogezand, D.K. Podolsky, B.E. Sands, T. Braakman, K.L. DeWoody, T.F. Schaible, S.J.H. van Deventer Infliximab for the treatment of fistulas in patients with Crohn's disease N Engl J Med 340 1999 1398 1405
8. D.H. Present Crohn's fistula current concepts in management Gastroenterology 124 2003 1629 1635
9. D.H. Present, S. Lichtiger Efficacy of cyclosporine in treatment of fistula of Crohn's disease Dig Dis Sci 39 1994 374 380
10. S.B. Hanauer, M.B. Smith Rapid closure of Crohn's disease fistulas with continuous intravenous cyclosporin A Am J Gastroenterol 88 1993 646 649
11. B.I. Korelitz, D.H. Present Favorable effect of 6-mercaptopurine on fistulae of Crohn's disease Dig Dis Sci 30 1985 58 64
12. J.J. O'Brien, T.M. Bayless, J.A. Bayless Use of azathioprine or 6-mercaptopurine in the treatment of Crohn's disease Gastroenterology 101 1991 39 46
13. M. Rusche, J. O'Brien Infliximab in the management of rectovaginal fistulous Crohn's disease Am J Gastroenterol 96 suppl 9 2001 S306 S307
14. MA. Parsi, JP. Achkar, BA. Lashner, A. Brzezinski Infliximab is more efficacious for treatment of enterocutaneous fistulas compared to rectovaginal fistulas in patients with Crohn's disease Gastroenterology 120 suppl 5 2001 A622
15. B.E. Sands, F.H. Anderson, C.N. Bernstein, W.Y. Chey, B.G. Feagan, R.N. Fedorak, M.A. Kamm, J.R. Korzenik, B.A. Lashner, J.E. Onken, D. Rachmilewitz, P. Rutgeerts, G. Wild, D.C. Wolf, P.A. Marsters, S.B. Travers, M.A. Blank, S.J. van Deventer Infliximab maintenance therapy for fistulizing Crohn's disease N Engl J Med 350 2004 876 885
16. W.R. Best, J.M. Becktel, J.W. Singleton, F. Kern Jr Development of a Crohn's disease activity index. National Cooperative Crohn's Disease Study Gastroenterology 70 1976 439 444
17. E.J. Irvine, B. Feagan, J. Rochon, A. Archambault, R.N. Fedorak, A. Groll, D. Kinnear, F. Saibil, J.W.D. McDonald Canadian Crohn's Relapse Prevention Trial Quality of life a valid and reliable measure of therapeutic efficacy in the treatment of inflammatory bowel disease Gastroenterology 106 1994 287 296
18. J.C. Gregor, J.W.D. McDonald, N. Klar, R. Wall, K. Atkinson, B. Lamba, B.G. Feagan An evaluation of the utility measurement in Crohn's disease Inflamm Bowel Dis 3 1997 265 276
19. L.J. Egan, W.J. Sandborn, W.J. Tremaine Clinical outcome following treatment of refractory inflammatory and fistulizing Crohn's disease with intravenous cyclosporine Am J Gastroenterol 93 1998 442 448
20. M.A. Parsi, B.A. Lashner, J.P. Achkar, J.T. Connor, A. Brzezinski Type of fistula determines response to infliximab in patients with fistulous Crohn's disease Am J Gastroenterol 99 2004 445 449