RNA sequencing of microglia and monocyte-derived macrophages from mice with experimental autoimmune encephalomyelitis illustrates a changing phenotype with disease course

Journal of Neuroimmunology

Volumn 277, Issue 1-2, 2014, Pages 26-38

  Lewis, Nuruddeen D ^a   Hill, Jonathan D ^a   Juchem, Kathryn W ^a   Stefanopoulos, Dimitria E ^a   Modis, Louise K ^a  

^a BOEHRINGER INGELHEIM PHARMACEUTICALS INC   (United States)

Author keywords

EAE; Microglia; Monocytes; RNA Seq

Indexed keywords

CD11B ANTIGEN; CD45 ANTIGEN; HERMES ANTIGEN; LEUKOCYTE ANTIGEN; MYELIN OLIGODENDROCYTE GLYCOPROTEIN; MYELIN OLIGODENDROCYTE GLYCOPROTEIN (35-55); PEPTIDE FRAGMENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL COUNT; CELL DIFFERENTIATION; CELL PROLIFERATION; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DISEASE COURSE; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; FEMALE; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; GENE EXPRESSION; IN VIVO STUDY; MACROPHAGE; MICROGLIA; MOUSE; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; RNA SEQUENCE; UPREGULATION; ANIMAL; C57BL MOUSE; CHEMICALLY INDUCED; DISEASE MODEL; GENETICS; IMMUNOLOGY; METABOLISM; PATHOLOGY; PERITONEUM MACROPHAGE; PHYSIOLOGY; SIGNAL TRANSDUCTION; TIME; TOXICITY;

ANIMALS; ANTIGENS, CD; BASE SEQUENCE; CELL PROLIFERATION; DISEASE MODELS, ANIMAL; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FEMALE; FLOW CYTOMETRY; MACROPHAGES, PERITONEAL; MICE; MICE, INBRED C57BL; MICROGLIA; MYELIN-OLIGODENDROCYTE GLYCOPROTEIN; PEPTIDE FRAGMENTS; SIGNAL TRANSDUCTION; TIME FACTORS;

EID: 84919402088     PISSN: 01655728     EISSN: 18728421     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2014.09.014     Document Type: Article

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