메뉴 건너뛰기




Volumn 8, Issue , 2011, Pages

Loss of the receptor tyrosine kinase Axl leads to enhanced inflammation in the CNS and delayed removal of myelin debris during Experimental Autoimmune Encephalomyelitis

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN AXL; PROTEIN TYROSINE KINASE; UNCLASSIFIED DRUG; AXL RECEPTOR TYROSINE KINASE; CYTOKINE; GLYCOPROTEIN; MYELIN OLIGODENDROCYTE GLYCOPROTEIN (35 55); MYELIN OLIGODENDROCYTE GLYCOPROTEIN (35-55); ONCOPROTEIN; PEPTIDE FRAGMENT; TYRO3 PROTEIN, MOUSE;

EID: 79955836709     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/1742-2094-8-49     Document Type: Article
Times cited : (97)

References (54)
  • 1
    • 0033559140 scopus 로고    scopus 로고
    • A novel receptor tyrosine kinase, Mer, inhibits TNF-alpha production and lipopolysaccharide-induced endotoxic shock
    • Camenisch TD, Koller BH, Earp HS, Matsushima GK. A novel receptor tyrosine kinase, Mer, inhibits TNF-alpha production and lipopolysaccharide-induced endotoxic shock. J Immunol 1999, 162:3498-3503.
    • (1999) J Immunol , vol.162 , pp. 3498-3503
    • Camenisch, T.D.1    Koller, B.H.2    Earp, H.S.3    Matsushima, G.K.4
  • 2
    • 0035854442 scopus 로고    scopus 로고
    • Homeostatic regulation of the immune system by receptor tyrosine kinases of the Tyro 3 family
    • 10.1126/science.1061663, 11452127
    • Lu Q, Lemke G. Homeostatic regulation of the immune system by receptor tyrosine kinases of the Tyro 3 family. Science 2001, 293:306-311. 10.1126/science.1061663, 11452127.
    • (2001) Science , vol.293 , pp. 306-311
    • Lu, Q.1    Lemke, G.2
  • 5
    • 67649935007 scopus 로고    scopus 로고
    • Up-regulation of soluble Axl and Mer receptor tyrosine kinases negatively correlates with Gas6 in established multiple sclerosis lesions
    • 10.2353/ajpath.2009.080807, 2708814, 19541935
    • Weinger JG, Omari KM, Marsden K, Raine CS, Shafit-Zagardo B. Up-regulation of soluble Axl and Mer receptor tyrosine kinases negatively correlates with Gas6 in established multiple sclerosis lesions. Am J Pathol 2009, 175:283-293. 10.2353/ajpath.2009.080807, 2708814, 19541935.
    • (2009) Am J Pathol , vol.175 , pp. 283-293
    • Weinger, J.G.1    Omari, K.M.2    Marsden, K.3    Raine, C.S.4    Shafit-Zagardo, B.5
  • 9
    • 0027958327 scopus 로고
    • The proto-oncogene of v-eyk (v-ryk) is a novel receptor-type protein tyrosine kinase with extracellular Ig/GN-III domains
    • Jia R, Hanafusa H. The proto-oncogene of v-eyk (v-ryk) is a novel receptor-type protein tyrosine kinase with extracellular Ig/GN-III domains. J Biol Chem 1994, 269:1839-1844.
    • (1994) J Biol Chem , vol.269 , pp. 1839-1844
    • Jia, R.1    Hanafusa, H.2
  • 10
    • 0036213857 scopus 로고    scopus 로고
    • Identification of Gas6, a putative ligand for Sky and Axl receptor tyrosine kinases, as a novel neurotrophic factor for hippocampal neurons
    • 10.1002/jnr.10211, 11948660
    • Funakoshi H, Yonemasu T, Nakano T, Matumoto K, Nakamura T. Identification of Gas6, a putative ligand for Sky and Axl receptor tyrosine kinases, as a novel neurotrophic factor for hippocampal neurons. J Neurosci Res 2002, 68:150-160. 10.1002/jnr.10211, 11948660.
    • (2002) J Neurosci Res , vol.68 , pp. 150-160
    • Funakoshi, H.1    Yonemasu, T.2    Nakano, T.3    Matumoto, K.4    Nakamura, T.5
  • 11
    • 0038380512 scopus 로고    scopus 로고
    • The growth arrest-specific gene product Gas6 promotes the survival of human oligodendrocytes via a phosphatidylinositol 3-kinase-dependent pathway
    • Shankar SL, O'Guin K, Cammer M, McMorris FA, Stitt TN, Basch RS, Varnum B, Shafit-Zagardo B. The growth arrest-specific gene product Gas6 promotes the survival of human oligodendrocytes via a phosphatidylinositol 3-kinase-dependent pathway. J Neurosci 2003, 23:4208-4218.
    • (2003) J Neurosci , vol.23 , pp. 4208-4218
    • Shankar, S.L.1    O'Guin, K.2    Cammer, M.3    McMorris, F.A.4    Stitt, T.N.5    Basch, R.S.6    Varnum, B.7    Shafit-Zagardo, B.8
  • 12
    • 43249084416 scopus 로고    scopus 로고
    • Elevation of Gas6 protein concentration in cerebrospinal fluid of patients with chronic inflammatory demyelinating polyneuropathy (CIDP)
    • 10.1016/j.jns.2008.01.005, 18279894
    • Sainaghi PP, Collimedaglia L, Alciato F, Leone MA, Puta E, Naldi P, Castello L, Monaco F, Avanzi GC. Elevation of Gas6 protein concentration in cerebrospinal fluid of patients with chronic inflammatory demyelinating polyneuropathy (CIDP). J Neurol Sci 2008, 269:138-142. 10.1016/j.jns.2008.01.005, 18279894.
    • (2008) J Neurol Sci , vol.269 , pp. 138-142
    • Sainaghi, P.P.1    Collimedaglia, L.2    Alciato, F.3    Leone, M.A.4    Puta, E.5    Naldi, P.6    Castello, L.7    Monaco, F.8    Avanzi, G.C.9
  • 13
    • 0027182792 scopus 로고
    • The protein encoded by a growth arrest-specific gene (gas6) is a new member of the vitamin K-dependent proteins related to protein S, a negative coregulator in the blood coagulation cascade
    • 360142, 8336730
    • Manfioletti G, Brancolini C, Avanzi G, Schneider C. The protein encoded by a growth arrest-specific gene (gas6) is a new member of the vitamin K-dependent proteins related to protein S, a negative coregulator in the blood coagulation cascade. Mol Cell Biol 1993, 13:4976-4985. 360142, 8336730.
    • (1993) Mol Cell Biol , vol.13 , pp. 4976-4985
    • Manfioletti, G.1    Brancolini, C.2    Avanzi, G.3    Schneider, C.4
  • 14
    • 0033596536 scopus 로고    scopus 로고
    • Gas6, a ligand for the receptor protein-tyrosine kinase Tyro-3, is widely expressed in the central nervous system
    • 10.1016/S0006-8993(98)01159-7, 9878891
    • Prieto AL, Weber JL, Tracy S, Heeb MJ, Lai C. Gas6, a ligand for the receptor protein-tyrosine kinase Tyro-3, is widely expressed in the central nervous system. Brain Res 1999, 816:646-661. 10.1016/S0006-8993(98)01159-7, 9878891.
    • (1999) Brain Res , vol.816 , pp. 646-661
    • Prieto, A.L.1    Weber, J.L.2    Tracy, S.3    Heeb, M.J.4    Lai, C.5
  • 15
    • 54549123319 scopus 로고    scopus 로고
    • Axl-/- mice have delayed recovery and prolonged axonal damage following cuprizone toxicity
    • Hoehn HJ, Kress Y, Sohn A, Brosnan CF, Bourdon S, Shafit-Zagardo B. Axl-/- mice have delayed recovery and prolonged axonal damage following cuprizone toxicity. Brain Res 2008, 1240:1-11.
    • (2008) Brain Res , vol.1240 , pp. 1-11
    • Hoehn, H.J.1    Kress, Y.2    Sohn, A.3    Brosnan, C.F.4    Bourdon, S.5    Shafit-Zagardo, B.6
  • 17
    • 33746894720 scopus 로고    scopus 로고
    • Twist mediates suppression of inflammation by type I IFNs and Axl
    • 10.1084/jem.20051725, 2118370, 16831897
    • Sharif MN, Sosic D, Rothlin CV, Kelly E, Lemke G, Olson EN, Ivashkiv LB. Twist mediates suppression of inflammation by type I IFNs and Axl. J Exp Med 2006, 203:1891-1901. 10.1084/jem.20051725, 2118370, 16831897.
    • (2006) J Exp Med , vol.203 , pp. 1891-1901
    • Sharif, M.N.1    Sosic, D.2    Rothlin, C.V.3    Kelly, E.4    Lemke, G.5    Olson, E.N.6    Ivashkiv, L.B.7
  • 18
    • 0032920496 scopus 로고    scopus 로고
    • Expression of MCP-1 by reactive astrocytes in demyelinating multiple sclerosis lesions
    • 10.1016/S0002-9440(10)65249-2, 1853444, 9916917
    • Van Der Voorn P, Tekstra J, Beelen RH, Tensen CP, Van Der Valk P, De Groot CJ. Expression of MCP-1 by reactive astrocytes in demyelinating multiple sclerosis lesions. Am J Pathol 1999, 154:45-51. 10.1016/S0002-9440(10)65249-2, 1853444, 9916917.
    • (1999) Am J Pathol , vol.154 , pp. 45-51
    • Van Der Voorn, P.1    Tekstra, J.2    Beelen, R.H.3    Tensen, C.P.4    Van Der Valk, P.5    De Groot, C.J.6
  • 19
    • 0028941871 scopus 로고
    • The adhesion molecule and cytokine profile of multiple sclerosis lesions
    • 10.1002/ana.410370404, 7536402
    • Cannella B, Raine CS. The adhesion molecule and cytokine profile of multiple sclerosis lesions. Ann Neurol 1995, 37:424-435. 10.1002/ana.410370404, 7536402.
    • (1995) Ann Neurol , vol.37 , pp. 424-435
    • Cannella, B.1    Raine, C.S.2
  • 20
    • 0024366885 scopus 로고
    • Tumor necrosis factor identified in multiple sclerosis brain
    • 10.1084/jem.170.2.607, 2189402, 2754393
    • Hofman FM, Hinton DR, Johnson K, Merrill JE. Tumor necrosis factor identified in multiple sclerosis brain. J Exp Med 1989, 170:607-612. 10.1084/jem.170.2.607, 2189402, 2754393.
    • (1989) J Exp Med , vol.170 , pp. 607-612
    • Hofman, F.M.1    Hinton, D.R.2    Johnson, K.3    Merrill, J.E.4
  • 21
    • 0025852567 scopus 로고
    • Identification of lymphotoxin and tumor necrosis factor in multiple sclerosis lesions
    • 10.1172/JCI115102, 329886, 1999503
    • Selmaj K, Raine CS, Cannella B, Brosnan CF. Identification of lymphotoxin and tumor necrosis factor in multiple sclerosis lesions. J Clin Invest 1991, 87:949-954. 10.1172/JCI115102, 329886, 1999503.
    • (1991) J Clin Invest , vol.87 , pp. 949-954
    • Selmaj, K.1    Raine, C.S.2    Cannella, B.3    Brosnan, C.F.4
  • 22
    • 17044372405 scopus 로고    scopus 로고
    • CCL2 and CCL5 mediate leukocyte adhesion in experimental autoimmune encephalomyelitis--an intravital microscopy study
    • 10.1016/j.jneuroim.2005.01.020, 15833367
    • dos Santos AC, Barsante MM, Arantes RM, Bernard CC, Teixeira MM, Carvalho-Tavares J. CCL2 and CCL5 mediate leukocyte adhesion in experimental autoimmune encephalomyelitis--an intravital microscopy study. J Neuroimmunol 2005, 162:122-129. 10.1016/j.jneuroim.2005.01.020, 15833367.
    • (2005) J Neuroimmunol , vol.162 , pp. 122-129
    • dos Santos, A.C.1    Barsante, M.M.2    Arantes, R.M.3    Bernard, C.C.4    Teixeira, M.M.5    Carvalho-Tavares, J.6
  • 23
    • 0028985320 scopus 로고
    • Tumor necrosis factor-alpha messenger RNA expression in patients with relapsing-remitting multiple sclerosis is associated with disease activity
    • 10.1002/ana.410370115, 7818262
    • Rieckmann P, Albrecht M, Kitze B, Weber T, Tumani H, Broocks A, Luer W, Helwig A, Poser S. Tumor necrosis factor-alpha messenger RNA expression in patients with relapsing-remitting multiple sclerosis is associated with disease activity. Ann Neurol 1995, 37:82-88. 10.1002/ana.410370115, 7818262.
    • (1995) Ann Neurol , vol.37 , pp. 82-88
    • Rieckmann, P.1    Albrecht, M.2    Kitze, B.3    Weber, T.4    Tumani, H.5    Broocks, A.6    Luer, W.7    Helwig, A.8    Poser, S.9
  • 24
    • 0029865040 scopus 로고    scopus 로고
    • Pretreatment with T cell receptor peptides using a conventional immunization protocol does not induce effective protection against autoimmune encephalomyelitis
    • 10.1006/cimm.1996.0052, 8599843
    • Tanuma N, Abe S, Shin T, Kojima T, Ishihara Y, Arai Y, Toyoshima S, Matsumoto Y. Pretreatment with T cell receptor peptides using a conventional immunization protocol does not induce effective protection against autoimmune encephalomyelitis. Cell Immunol 1996, 168:85-90. 10.1006/cimm.1996.0052, 8599843.
    • (1996) Cell Immunol , vol.168 , pp. 85-90
    • Tanuma, N.1    Abe, S.2    Shin, T.3    Kojima, T.4    Ishihara, Y.5    Arai, Y.6    Toyoshima, S.7    Matsumoto, Y.8
  • 25
    • 60149098421 scopus 로고    scopus 로고
    • Debris clearance by microglia: an essential link between degeneration and regeneration
    • 2640215, 18567623
    • Neumann H, Kotter MR, Franklin RJ. Debris clearance by microglia: an essential link between degeneration and regeneration. Brain 2009, 132:288-295. 2640215, 18567623.
    • (2009) Brain , vol.132 , pp. 288-295
    • Neumann, H.1    Kotter, M.R.2    Franklin, R.J.3
  • 28
    • 35548986304 scopus 로고    scopus 로고
    • Microglia: active sensor and versatile effector cells in the normal and pathologic brain
    • 10.1038/nn1997, 17965659
    • Hanisch UK, Kettenmann H. Microglia: active sensor and versatile effector cells in the normal and pathologic brain. Nat Neurosci 2007, 10:1387-1394. 10.1038/nn1997, 17965659.
    • (2007) Nat Neurosci , vol.10 , pp. 1387-1394
    • Hanisch, U.K.1    Kettenmann, H.2
  • 29
    • 77956961694 scopus 로고    scopus 로고
    • Neuroinflammatory processes in Alzheimer's disease
    • 10.1007/s00702-010-0438-z, 20632195
    • Heneka MT, O'Banion MK, Terwel D, Kummer MP. Neuroinflammatory processes in Alzheimer's disease. J Neural Transm 2010, 117:919-947. 10.1007/s00702-010-0438-z, 20632195.
    • (2010) J Neural Transm , vol.117 , pp. 919-947
    • Heneka, M.T.1    O'Banion, M.K.2    Terwel, D.3    Kummer, M.P.4
  • 30
    • 34247580796 scopus 로고    scopus 로고
    • Macrophages and dendritic cells use different Axl/Mertk/Tyro3 receptors in clearance of apoptotic cells
    • Seitz HM, Camenisch TD, Lemke G, Earp HS, Matsushima GK. Macrophages and dendritic cells use different Axl/Mertk/Tyro3 receptors in clearance of apoptotic cells. J Immunol 2007, 178:5635-5642.
    • (2007) J Immunol , vol.178 , pp. 5635-5642
    • Seitz, H.M.1    Camenisch, T.D.2    Lemke, G.3    Earp, H.S.4    Matsushima, G.K.5
  • 32
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • 10.1038/227680a0, 5432063
    • Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970, 227:680-685. 10.1038/227680a0, 5432063.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 33
    • 0009482260 scopus 로고
    • Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications
    • 10.1073/pnas.76.9.4350, 411572, 388439
    • Towbin H, Staehelin T, Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci USA 1979, 76:4350-4354. 10.1073/pnas.76.9.4350, 411572, 388439.
    • (1979) Proc Natl Acad Sci USA , vol.76 , pp. 4350-4354
    • Towbin, H.1    Staehelin, T.2    Gordon, J.3
  • 35
    • 33644535464 scopus 로고    scopus 로고
    • Exacerbation of experimental autoimmune encephalomyelitis in P2X7R-/- mice: evidence for loss of apoptotic activity in lymphocytes
    • Chen L, Brosnan CF. Exacerbation of experimental autoimmune encephalomyelitis in P2X7R-/- mice: evidence for loss of apoptotic activity in lymphocytes. J Immunol 2006, 176:3115-3126.
    • (2006) J Immunol , vol.176 , pp. 3115-3126
    • Chen, L.1    Brosnan, C.F.2
  • 36
    • 54249154831 scopus 로고    scopus 로고
    • Multianalyte profiling of serum antigens and autoimmune and infectious disease molecules to identify biomarkers dysregulated in epithelial ovarian cancer
    • 10.1158/1055-9965.EPI-08-0464, 18843033
    • Bertenshaw GP, Yip P, Seshaiah P, Zhao J, Chen TH, Wiggins WS, Mapes JP, Mansfield BC. Multianalyte profiling of serum antigens and autoimmune and infectious disease molecules to identify biomarkers dysregulated in epithelial ovarian cancer. Cancer Epidemiol Biomarkers Prev 2008, 17:2872-2881. 10.1158/1055-9965.EPI-08-0464, 18843033.
    • (2008) Cancer Epidemiol Biomarkers Prev , vol.17 , pp. 2872-2881
    • Bertenshaw, G.P.1    Yip, P.2    Seshaiah, P.3    Zhao, J.4    Chen, T.H.5    Wiggins, W.S.6    Mapes, J.P.7    Mansfield, B.C.8
  • 37
    • 68149168633 scopus 로고    scopus 로고
    • Incorporation of NKT cell-activating glycolipids enhances immunogenicity and vaccine efficacy of Mycobacterium bovis bacillus Calmette-Guerin
    • 10.4049/jimmunol.0900858, 2719834, 19620317
    • Venkataswamy MM, Baena A, Goldberg MF, Bricard G, Im JS, Chan J, Reddington F, Besra GS, Jacobs WR, Porcelli SA. Incorporation of NKT cell-activating glycolipids enhances immunogenicity and vaccine efficacy of Mycobacterium bovis bacillus Calmette-Guerin. J Immunol 2009, 183:1644-1656. 10.4049/jimmunol.0900858, 2719834, 19620317.
    • (2009) J Immunol , vol.183 , pp. 1644-1656
    • Venkataswamy, M.M.1    Baena, A.2    Goldberg, M.F.3    Bricard, G.4    Im, J.S.5    Chan, J.6    Reddington, F.7    Besra, G.S.8    Jacobs, W.R.9    Porcelli, S.A.10
  • 38
    • 44849139232 scopus 로고    scopus 로고
    • Met and c-Src cooperate to compensate for loss of epidermal growth factor receptor kinase activity in breast cancer cells
    • 10.1158/0008-5472.CAN-08-0132, 18451158
    • Mueller KL, Hunter LA, Ethier SP, Boerner JL. Met and c-Src cooperate to compensate for loss of epidermal growth factor receptor kinase activity in breast cancer cells. Cancer Res 2008, 68:3314-3322. 10.1158/0008-5472.CAN-08-0132, 18451158.
    • (2008) Cancer Res , vol.68 , pp. 3314-3322
    • Mueller, K.L.1    Hunter, L.A.2    Ethier, S.P.3    Boerner, J.L.4
  • 39
    • 0028938732 scopus 로고
    • The transforming receptor tyrosine kinase, Axl, is post-translationally regulated by proteolytic cleavage
    • 10.1074/jbc.270.2.551, 7822279
    • O'Bryan JP, Fridell YW, Koski R, Varnum B, Liu ET. The transforming receptor tyrosine kinase, Axl, is post-translationally regulated by proteolytic cleavage. J Biol Chem 1995, 270:551-557. 10.1074/jbc.270.2.551, 7822279.
    • (1995) J Biol Chem , vol.270 , pp. 551-557
    • O'Bryan, J.P.1    Fridell, Y.W.2    Koski, R.3    Varnum, B.4    Liu, E.T.5
  • 40
    • 0036788406 scopus 로고    scopus 로고
    • Acute axonal damage in multiple sclerosis is most extensive in early disease stages and decreases over time
    • 10.1093/brain/awf235, 12244078
    • Kuhlmann T, Lingfeld G, Bitsch A, Schuchardt J, Bruck W. Acute axonal damage in multiple sclerosis is most extensive in early disease stages and decreases over time. Brain 2002, 125:2202-2212. 10.1093/brain/awf235, 12244078.
    • (2002) Brain , vol.125 , pp. 2202-2212
    • Kuhlmann, T.1    Lingfeld, G.2    Bitsch, A.3    Schuchardt, J.4    Bruck, W.5
  • 43
    • 0027445232 scopus 로고
    • TNF alpha induces expression of the chemoattractant cytokine RANTES in cultured mouse mesangial cells
    • 10.1038/ki.1993.314, 7505037
    • Wolf G, Aberle S, Thaiss F, Nelson PJ, Krensky AM, Neilson EG, Stahl RA. TNF alpha induces expression of the chemoattractant cytokine RANTES in cultured mouse mesangial cells. Kidney Int 1993, 44:795-804. 10.1038/ki.1993.314, 7505037.
    • (1993) Kidney Int , vol.44 , pp. 795-804
    • Wolf, G.1    Aberle, S.2    Thaiss, F.3    Nelson, P.J.4    Krensky, A.M.5    Neilson, E.G.6    Stahl, R.A.7
  • 44
    • 2442680279 scopus 로고    scopus 로고
    • Dual regulation of tumor necrosis factor-alpha-induced CCL2/monocyte chemoattractant protein-1 expression in vascular smooth muscle cells by nuclear factor-kappaB and activator protein-1: modulation by type III phosphodiesterase inhibition
    • 10.1124/jpet.103.062620, 14978197
    • Chen YM, Chiang WC, Lin SL, Wu KD, Tsai TJ, Hsieh BS. Dual regulation of tumor necrosis factor-alpha-induced CCL2/monocyte chemoattractant protein-1 expression in vascular smooth muscle cells by nuclear factor-kappaB and activator protein-1: modulation by type III phosphodiesterase inhibition. J Pharmacol Exp Ther 2004, 309:978-986. 10.1124/jpet.103.062620, 14978197.
    • (2004) J Pharmacol Exp Ther , vol.309 , pp. 978-986
    • Chen, Y.M.1    Chiang, W.C.2    Lin, S.L.3    Wu, K.D.4    Tsai, T.J.5    Hsieh, B.S.6
  • 45
    • 0031713961 scopus 로고    scopus 로고
    • Expression of chemokines RANTES, MIP-1alpha and GRO-alpha correlates with inflammation in acute experimental autoimmune encephalomyelitis
    • 10.1159/000026333, 9730682
    • Glabinski AR, Tuohy VK, Ransohoff RM. Expression of chemokines RANTES, MIP-1alpha and GRO-alpha correlates with inflammation in acute experimental autoimmune encephalomyelitis. Neuroimmunomodulation 1998, 5:166-171. 10.1159/000026333, 9730682.
    • (1998) Neuroimmunomodulation , vol.5 , pp. 166-171
    • Glabinski, A.R.1    Tuohy, V.K.2    Ransohoff, R.M.3
  • 46
    • 0029270425 scopus 로고
    • Microglia, the first line of defence in brain pathologies
    • Kreutzberg GW. Microglia, the first line of defence in brain pathologies. Arzneimittelforschung 1995, 45:357-360.
    • (1995) Arzneimittelforschung , vol.45 , pp. 357-360
    • Kreutzberg, G.W.1
  • 49
    • 0036135698 scopus 로고    scopus 로고
    • Novel mechanism for gonadotropin-releasing hormone neuronal migration involving Gas6/Ark signaling to p38 mitogen-activated protein kinase
    • 10.1128/MCB.22.2.599-613.2002, 139735, 11756555
    • Allen MP, Linseman DA, Udo H, Xu M, Schaack JB, Varnum B, Kandel ER, Heidenreich KA, Wierman ME. Novel mechanism for gonadotropin-releasing hormone neuronal migration involving Gas6/Ark signaling to p38 mitogen-activated protein kinase. Mol Cell Biol 2002, 22:599-613. 10.1128/MCB.22.2.599-613.2002, 139735, 11756555.
    • (2002) Mol Cell Biol , vol.22 , pp. 599-613
    • Allen, M.P.1    Linseman, D.A.2    Udo, H.3    Xu, M.4    Schaack, J.B.5    Varnum, B.6    Kandel, E.R.7    Heidenreich, K.A.8    Wierman, M.E.9
  • 50
    • 40349089504 scopus 로고    scopus 로고
    • The biology of CNS remyelination: the key to therapeutic advances
    • Franklin RJ, Kotter MR. The biology of CNS remyelination: the key to therapeutic advances. J Neurol 2008, 255(Suppl 1):19-25.
    • (2008) J Neurol , vol.255 , Issue.SUPPL. 1 , pp. 19-25
    • Franklin, R.J.1    Kotter, M.R.2
  • 52
    • 0035101569 scopus 로고    scopus 로고
    • In vivo measurement of the size of lipid droplets in an intracerebral glioma in the rat
    • 10.1002/1522-2594(200103)45:3<409::AID-MRM1053>3.0.CO;2-O, 11241697
    • Lahrech H, Zoula S, Farion R, Rémy C, Décorps M. In vivo measurement of the size of lipid droplets in an intracerebral glioma in the rat. Magn Reson Med 2001, 45:409-414. 10.1002/1522-2594(200103)45:3<409::AID-MRM1053>3.0.CO;2-O, 11241697.
    • (2001) Magn Reson Med , vol.45 , pp. 409-414
    • Lahrech, H.1    Zoula, S.2    Farion, R.3    Rémy, C.4    Décorps, M.5
  • 53
    • 1942452889 scopus 로고    scopus 로고
    • Pitfalls in the detection of lipid vectors in neural cell culture and in brain tissue
    • Rizk T, Montero-Menei C, Jollivet C, Benoit JP, Menei P. Pitfalls in the detection of lipid vectors in neural cell culture and in brain tissue. J Biomed Mater Res A 2004, 68:360-364.
    • (2004) J Biomed Mater Res A , vol.68 , pp. 360-364
    • Rizk, T.1    Montero-Menei, C.2    Jollivet, C.3    Benoit, J.P.4    Menei, P.5
  • 54
    • 42649140235 scopus 로고    scopus 로고
    • Immunobiology of the TAM receptors
    • 10.1038/nri2303, 2856445, 18421305
    • Lemke G, Rothlin CV. Immunobiology of the TAM receptors. Nat Rev Immunol 2008, 8:327-336. 10.1038/nri2303, 2856445, 18421305.
    • (2008) Nat Rev Immunol , vol.8 , pp. 327-336
    • Lemke, G.1    Rothlin, C.V.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.