Effects of selenium on lead-induced alterations in Aβ production and Bcl-2 family proteins

Environmental Toxicology and Pharmacology

Volumn 39, Issue 1, 2015, Pages 221-228

  Deng, Zhiqiang ^a,b   Fu, Hongjun ^c   Xiao, Yongmei ^a   Zhang, Bo ^a   Sun, Guangshun ^a   Wei, Qing ^a   Ai, Baomin ^a   Hu, Qiansheng ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b Nanchang Center for Disease Control and Prevention   (China)

^c JACKSON LABORATORY   (United States)

Author keywords

Amyloid beta protein; Amyloid precursor protein; Bax; Bcl 2; Lead; Selenium

Indexed keywords

AMYLOID BETA PROTEIN[1-40]; AMYLOID PRECURSOR PROTEIN; LEAD; LEAD ACETATE; MESSENGER RNA; PROTEIN BAX; PROTEIN BCL 2; SELENOMETHIONINE; AMYLOID BETA PROTEIN; BAX PROTEIN, RAT; NEUROPROTECTIVE AGENT; PEPTIDE FRAGMENT; SELENIUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; BRAIN DEVELOPMENT; CELL LEVEL; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; EMBRYO; HUMAN; HUMAN CELL; IN VITRO STUDY; NERVE CELL NECROSIS; NEUROPROTECTION; NEUROTOXICITY; NEWBORN; NONHUMAN; PROTEIN EXPRESSION; PROTEIN SECRETION; RAT; WISTAR RAT; ANIMAL; DRUG EFFECTS; FEMALE; GENETICS; HIPPOCAMPUS; METABOLISM; TUMOR CELL LINE;

ANIMALIA; RATTUS NORVEGICUS;

AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; BCL-2-ASSOCIATED X PROTEIN; CELL LINE, TUMOR; FEMALE; HIPPOCAMPUS; HUMANS; LEAD; NEUROPROTECTIVE AGENTS; PEPTIDE FRAGMENTS; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS, WISTAR; SELENIUM;

EID: 84918781458     PISSN: 13826689     EISSN: 18727077     Source Type: Journal    
DOI: 10.1016/j.etap.2014.11.010     Document Type: Article

References (42)

1. Ayala-Grosso C., Ng G., Roy S., Robertson G.S. Caspase-cleaved amyloid precursor protein in Alzheimer's disease. Brain Pathol. 2002, 12:430-441.
2. Basha M.R., Wei W., Bakheet S.A., Benitez N., Siddiqi H.K., Ge Y.W., Lahiri D.K., Zawia N.H. The fetal basis of amyloidogenesis: exposure to lead and latent overexpression of amyloid precursor protein and beta-amyloid in the aging brain. J. Neurosci. 2005, 25:823-829.
3. Behl M., Zhang Y., Shi Y., Cheng J., Du Y., Zheng W. Lead-induced accumulation of beta-amyloid in the choroid plexus: role of low density lipoprotein receptor protein-1 and protein kinase C. Neurotoxicology 2010, 31:524-532.
4. Benton D. Selenium intake, mood and other aspects of psychological functioning. Nutr. Neurosci. 2002, 5:363-374.
5. Braun J.M., Kahn R.S., Froehlich T., Auinger P., Lanphear B.P. Exposures to environmental toxicants and attention deficit hyperactivity disorder in U.S. children. Environ. Health Perspect. 2006, 114:1904-1909.
6. Chen J., Berry M.J. Selenium and selenoproteins in the brain and brain diseases. J. Neurochem. 2003, 86:1-12.
7. Corcoran N.M., Martin D., Hutter-Paier B., Windisch M., Nguyen T., Nheu L., Sundstrom L.E., Costello A.J., Hovens C.M. Sodium selenate specifically activates PP2A phosphatase, dephosphorylates tau and reverses memory deficits in an Alzheimer's disease model. J. Clin. Neurosci. 2010, 17:1025-1033.
8. Ferreiro E., Eufrasio A., Pereira C., Oliveira C.R., Rego A.C. Bcl-2 overexpression protects against amyloid-beta and prion toxicity in GT1-7 neural cells. J. Alzheimers Dis. 2007, 12:223-228.
9. Gervais F.G., Xu D., Robertson G.S., Vaillancourt J.P., Zhu Y., Huang J., LeBlanc A., Smith D., Rigby M., Shearman M.S., Clarke E.E., Zheng H., Van Der Ploeg L.H., Ruffolo S.C., Thornberry N.A., Xanthoudakis S., Zamboni R.J., Roy S., Nicholson D.W. Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid-beta precursor protein and amyloidogenic A beta peptide formation. Cell 1999, 97:395-406.
10. Godoi G.L., de Oliveira P.L., Schulz J.F., Kaufmann F.N., Da R.J., de Souza D.O., Ghisleni G., de Almeida H.J. Selenium compounds prevent amyloid beta-peptide neurotoxicity in rat primary hippocampal neurons. Neurochem. Res. 2013, 38:2359-2363.
11. Gu H., Robison G., Hong L., Barrea R., Wei X., Farlow M.R., Pushkar Y.N., Du Y., Zheng W. Increased beta-amyloid deposition in Tg-SWDI transgenic mouse brain following in vivo lead exposure. Toxicol. Lett. 2012, 213:211-219.
12. Guzel S., Kiziler L., Aydemir B., Alici B., Ataus S., Aksu A., Durak H. Association of Pb, Cd, and Se concentrations and oxidative damage-related markers in different grades of prostate carcinoma. Biol. Trace Elem. Res. 2012, 145:23-32.
13. Gwon A.R., Park J.S., Park J.H., Baik S.H., Jeong H.Y., Hyun D.H., Park K.W., Jo D.G. Selenium attenuates A beta production and A beta-induced neuronal death. Neurosci. Lett. 2010, 469:391-395.
14. Hebert L.E., Scherr P.A., Bienias J.L., Bennett D.A., Evans D.A. Alzheimer disease in the US population: prevalence estimates using the 2000 census. Arch. Neurol. 2003, 60:1119-1122.
15. Hernandez F., Gomez D.B.E., Fuster-Matanzo A., Lucas J.J., Avila J. GSK3: a possible link between beta amyloid peptide and tau protein. Exp. Neurol. 2010, 223:322-325.
16. Huang, H., Bihaqi, S.W., Cui, L., Zawia, N.H., 2011. In vitro Pb exposure disturbs the balance between Abeta production and elimination: the role of AbetaPP and neprilysin. Neurotoxicology 32, 300-306.
17. Ishrat T., Parveen K., Khan M.M., Khuwaja G., Khan M.B., Yousuf S., Ahmad A., Shrivastav P., Islam F. Selenium prevents cognitive decline and oxidative damage in rat model of streptozotocin-induced experimental dementia of Alzheimer's type. Brain Res. 2009, 1281:117-127.
18. Kumar M., Bijo A.J., Baghel R.S., Reddy C.R., Jha B. Selenium and spermine alleviate cadmium induced toxicity in the red seaweed Gracilaria dura by regulating antioxidants and DNA methylation. Plant Physiol. Biochem. 2012, 51:129-138.
19. Lemire M., Fillion M., Frenette B., Passos C.J., Guimaraes J.R., Barbosa F.J., Mergler D. Selenium from dietary sources and motor functions in the Brazilian Amazon. Neurotoxicology 2011, 32:944-953.
20. Li Y.Y., Chen T., Wan Y., Xu S.Q. Lead exposure in pheochromocytoma cells induces persistent changes in amyloid precursor protein gene methylation patterns. Environ. Toxicol. 2012, 27:495-502.
21. Lovell M.A., Xiong S., Lyubartseva G., Markesbery W.R. Organoselenium (Sel-Plex diet) decreases amyloid burden and RNA and DNA oxidative damage in APP/PS1 mice. Free Radic. Biol. Med. 2009, 46:1527-1533.
22. Migliore L., Coppede F. Genetics, environmental factors and the emerging role of epigenetics in neurodegenerative diseases. Mutat. Res. 2009, 667:82-97.
23. Nunomura A., Perry G., Aliev G., Hirai K., Takeda A., Balraj E.K., Jones P.K., Ghanbari H., Wataya T., Shimohama S., Chiba S., Atwood C.S., Petersen R.B., Smith M.A. Oxidative damage is the earliest event in Alzheimer disease. J. Neuropathol. Exp. Neurol. 2001, 60:759-767.
24. Ogomori K., Kitamoto T., Tateishi J., Sato Y., Suetsugu M., Abe M. Beta-protein amyloid is widely distributed in the central nervous system of patients with Alzheimer's disease. Am. J. Pathol. 1989, 134:243-251.
25. Pettmann B., Henderson C.E. Neuronal cell death. Neuron 1998, 20:633-647.
26. Rayman M.P. The importance of selenium to human health. Lancet 2000, 356:233-241.
27. Rayman M., Thompson A., Warren-Perry M., Galassini R., Catterick J., Hall E., Lawrence D., Bliss J. Impact of selenium on mood and quality of life: a randomized, controlled trial. Biol. Psychiatry 2006, 59:147-154.
28. Rodriguez-Estival J., Martinez-Haro M., Monsalve-Gonzalez L., Mateo R. Interactions between endogenous and dietary antioxidants against Pb-induced oxidative stress in wild ungulates from a Pb polluted mining area. Sci. Total Environ. 2011, 409:2725-2733.
29. Smith M.A. Alzheimer disease. Int. Rev. Neurobiol. 1998, 42:1-54.
30. Song G., Zhang Z., Wen L., Chen C., Shi Q., Zhang Y., Ni J., Liu Q. Selenomethionine ameliorates cognitive decline, reduces tau hyperphosphorylation, and reverses synaptic deficit in the triple transgenic mouse model of Alzheimer's disease. J. Alzheimers Dis. 2014, 41(1):85-99.
31. Strasser A., Huang D.C., Vaux D.L. The role of the bcl-2/ced-9 gene family in cancer and general implications of defects in cell death control for tumourigenesis and resistance to chemotherapy. Biochim. Biophys. Acta 1997, 1333:F151-F178.
32. Tang Y., Jia Q., Ma P., Li F., Lv T., Ha X. The effects of lead exposure on primary cultured hippocampus neurons apoptosis and the expressions of Bcl-2, Bax, p53 and NOS1. Wei Sheng Yan Jiu 2010, 39:235-238.
33. Tung Y.T., Hsu W.M., Wang B.J., Wu S.Y., Yen C.T., Hu M.K., Liao Y.F. Sodium selenite inhibits gamma-secretase activity through activation of ERK. Neurosci. Lett. 2008, 440:38-43.
34. van Eersel J., Ke Y.D., Liu X., Delerue F., Kril J.J., Gotz J., Ittner L.M. Sodium selenate mitigates tau pathology, neurodegeneration, and functional deficits in Alzheimer's disease models. Proc. Natl. Acad. Sci. U. S. A. 2010, 107:13888-13893.
35. Wang M., Fu H., Xiao Y., Ai B., Wei Q., Wang S., Liu T., Ye L., Hu Q. Effects of low-level organic selenium on lead-induced alterations in neural cell adhesion molecules. Brain Res. 2013, 1530:76-81.
36. Wang X., Zhang D. Alzheimer's disease related-genes and apoptosis. Sheng Li Ke Xue Jin Zhan 2001, 32:307-311.
37. White L.D., Cory-Slechta D.A., Gilbert M.E., Tiffany-Castiglioni E., Zawia N.H., Virgolini M., Rossi-George A., Lasley S.M., Qian Y.C., Basha M.R. New and evolving concepts in the neurotoxicology of lead. Toxicol. Appl. Pharmacol. 2007, 225:1-27.
38. Wu J., Basha M.R., Brock B., Cox D.P., Cardozo-Pelaez F., McPherson C.A., Harry J., Rice D.C., Maloney B., Chen D., Lahiri D.K., Zawia N.H. Alzheimer's disease (AD)-like pathology in aged monkeys after infantile exposure to environmental metal lead (Pb): evidence for a developmental origin and environmental link for AD. J. Neurosci. 2008, 28:3-9.
39. Yim S.Y., Chae K.R., Shim S.B., Hong J.T., Park J.Y., Lee C.Y., Son H.J., Sheen Y.Y., Hwang D.Y. ERK activation induced by selenium treatment significantly downregulates beta/gamma-secretase activity and Tau phosphorylation in the transgenic rat overexpressing human selenoprotein M. Int. J. Mol. Med. 2009, 24:91-96.
40. Yim S.Y., Chae K.R., Shim S.B., Hong J.T., Park J.Y., Lee C.Y., Son H.J., Sheen Y.Y., Hwang D.Y. ERK activation induced by selenium treatment significantly downregulates beta/gamma-secretase activity and tau phosphorylation in the transgenic rat overexpressing human selenoprotein M. Int. J. Mol. Med. 2009, 24:91-96.
41. Zhao H., Yenari M.A., Cheng D., Sapolsky R.M., Steinberg G.K. Bcl-2 overexpression protects against neuron loss within the ischemic margin following experimental stroke and inhibits cytochrome c translocation and caspase-3 activity. J. Neurochem. 2003, 85:1026-1036.
42. Zhu X., Wang Y., Ogawa O., Lee H.G., Raina A.K., Siedlak S.L., Harris P.L., Fujioka H., Shimohama S., Tabaton M., Atwood C.S., Petersen R.B., Perry G., Smith M.A. Neuroprotective properties of Bcl-w in Alzheimer disease. J. Neurochem. 2004, 89:1233-1240.