The patched 1 tumor-suppressor gene protects the mouse lens from spontaneous and radiation-induced cataract

American Journal of Pathology

Volumn 185, Issue 1, 2015, Pages 85-95

  De Stefano, Ilaria ^a   Tanno, Barbara ^b   Giardullo, Paola ^a   Leonardi, Simona ^b   Pasquali, Emanuela ^b   Antonelli, Francesca ^b   Tanori, Mirella ^b   Casciati, Arianna ^b   Pazzaglia, Simonetta ^b   Saran, Anna ^b   Mancuso, Mariateresa ^b  

^a GUGLIELMO MARCONI UNIVERSITY   (Italy)

^b ENEA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

NERVE CELL ADHESION MOLECULE; PROTEIN; PROTEIN PATCHED 1; PROTEIN VIM; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR PAX6; TRANSCRIPTION FACTOR ZEB1; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; UVOMORULIN; CELL SURFACE RECEPTOR; HOMEODOMAIN PROTEIN; KRUPPEL LIKE FACTOR; PATCHED RECEPTORS; SHH PROTEIN, MOUSE; SMAD PROTEIN; VIMENTIN; ZEB1 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DISEASE PREDISPOSITION; EMBRYO DEVELOPMENT; EPITHELIAL MESENCHYMAL TRANSITION; EPITHELIUM CELL; FEMALE; GENE EXPRESSION; GENOTYPE; HETEROZYGOTE; IMMUNOREACTIVITY; IONIZING RADIATION; LENS EPITHELIUM; MALE; MOUSE; NONHUMAN; PLURIPOTENT STEM CELL; PROTEIN EXPRESSION; RADIATION CATARACT; RADIATION EXPOSURE; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR GENE; UPREGULATION; ALLELE; ANIMAL; CATARACT; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; LENS; METABOLISM; PATHOLOGY; RADIATION RESPONSE; TRANSGENIC MOUSE; X RAY;

ALLELES; ANIMALS; CATARACT; CELL PROLIFERATION; EPITHELIAL-MESENCHYMAL TRANSITION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HEDGEHOG PROTEINS; HETEROZYGOTE; HOMEODOMAIN PROTEINS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; LENS, CRYSTALLINE; MICE; MICE, TRANSGENIC; RECEPTORS, CELL SURFACE; SIGNAL TRANSDUCTION; SMAD PROTEINS; TRANSFORMING GROWTH FACTOR BETA; VIMENTIN; X-RAYS;

EID: 84918771078     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2014.09.019     Document Type: Article

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