Activation of the hedgehog signaling pathway in the developing lens stimulates ectopic FoxE3 expression and disruption in fiber cell differentiation

Investigative Ophthalmology and Visual Science

Volumn 53, Issue 7, 2012, Pages 3316-3330

  Kerr, Christine L ^a   Huang, Jian ^b   Williams, Trevor ^b   West Mays, Judith A ^a  

^a MCMASTER UNIVERSITY MEDICAL CENTRE   (Canada)

^b UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA CRYSTALLIN; BETA CRYSTALLIN; BETA GALACTOSIDASE; CALRETININ; CYCLIN D; CYCLIN DEPENDENT KINASE INHIBITOR 1B; CYCLIN DEPENDENT KINASE INHIBITOR 1C; CYCLINE; FORKHEAD BOX E3 PROTEIN; HISTONE H3; PROTEIN PATCHED 1; SMOOTHENED PROTEIN; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR C MAF; TRANSCRIPTION FACTOR PAX6; UNCLASSIFIED DRUG;

ALLELE; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DEATH; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; EMBRYO; EYE DEVELOPMENT; GENOTYPING TECHNIQUE; HISTOLOGY; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; LENS EPITHELIUM; LENS FIBER; MOUSE; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ALLELES; ANIMALS; CELL DEATH; CELL DIFFERENTIATION; CELL PROLIFERATION; DNA; ECTODERM; EPITHELIAL CELLS; EYE PROTEINS; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEDGEHOG PROTEINS; HOMEODOMAIN PROTEINS; IN SITU NICK-END LABELING; LENS, CRYSTALLINE; MICE; MICE, MUTANT STRAINS; MICE, TRANSGENIC; ORGANOGENESIS; POLYMERASE CHAIN REACTION; PROTO-ONCOGENE PROTEINS C-MAF; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEINS;

EID: 84861981699     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.12-9595     Document Type: Article

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