Temporal changes in MMP mRNA expression in the lens epithelium during anterior subcapsular cataract formation

Experimental Eye Research

Volumn 88, Issue 2, 2009, Pages 323-330

  Nathu, Zahra ^a   Dwivedi, Dhruva J ^a   Reddan, John R ^b   Sheardown, Heather ^c   Margetts, Peter J ^c   West Mays, Judith A ^a  

^a MCMASTER UNIVERSITY   (Canada)

^b OAKLAND UNIVERSITY   (United States)

^c MCMASTER UNIVERSITY   (Canada)

Author keywords

ASC; cataract; EMT; lens; MMPs; TGF

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; GELATINASE A; GELATINASE B; MATRIX METALLOPROTEINASE; MESSENGER RNA; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CATARACT; CELL ISOLATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LASER CAPTURE MICRODISSECTION; LENS EPITHELIUM; NONHUMAN; PRIORITY JOURNAL; RAT; REAL TIME POLYMERASE CHAIN REACTION;

ACTINS; ANIMALS; CADHERINS; CATARACT; CELL LINE; CELL PROLIFERATION; EPITHELIAL CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; LENS CAPSULE, CRYSTALLINE; MALE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MATRIX METALLOPROTEINASES; MICRODISSECTION; MODELS, ANIMAL; RATS; RATS, WISTAR; RECOMBINANT PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TIME FACTORS; TRANSFORMING GROWTH FACTOR BETA;

EID: 61849162355     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exer.2008.08.014     Document Type: Article

References (40)

1. Bertelmann E., and Kojetinsky C. Posterior capsule opacification and anterior capsule opacification. Curr. Opin. Ophthalmol. 12 (2001) 35-40
2. Bhowmick N.A., Zent R., Ghiassi M., McDonnell M., and Moses H.L. Integrin beta 1 signaling is necessary for transforming growth factor-beta activation of p38MAPK and epithelial plasticity. J. Biol. Chem. 276 (2001) 46707-46713
3. Blechschmidt K., Kremmer E., Hollweck R., Mylonas I., Hofler H., Kremer M., and Becker K.F. The E-cadherin repressor snail plays a role in tumor progression of endometrioid adenocarcinomas. Diagn. Mol. Pathol. 16 (2007) 222-228
4. Bonner R.F., Emmert-Buck M., Cole K., Pohida T., Chuaqui R., Goldstein S., and Liotta L.A. Laser capture microdissection: molecular analysis of tissue. Science 278 1481 (1997) 1483
5. Cowden Dahl K.D., Symowicz J., Ning Y., Gutierrez E., Fishman D.A., Adley B.P., Stack M.S., and Hudson L.G. Matrix metalloproteinase 9 is a mediator of epidermal growth factor-dependent e-cadherin loss in ovarian carcinoma cells. Cancer Res. 68 (2008) 4606-4613
6. Dawes L.J., Elliott R.M., Reddan J.R., Wormstone Y.M., and Wormstone I.M. Oligonucleotide microarray analysis of human lens epithelial cells: TGFbeta regulated gene expression. Mol. Vis. 13 (2007) 1181-1197
7. Deryugina E.I., Ratnikov B., Monosov E., Postnova T.I., DiScipio R., Smith J.W., and Strongin A.Y. MT1-MMP initiates activation of pro-MMP-2 and integrin alphavbeta3 promotes maturation of MMP-2 in breast carcinoma cells. Exp. Cell Res. 263 (2001) 209-223
8. Dwivedi D.J., Pino G., Banh A., Nathu Z., Howchin D., Margetts P., Sivak J.G., and West-Mays J.A. Matrix metalloproteinase inhibitors suppress transforming growth factorbeta-induced subcapsular cataract formation. Am. J. Pathol. 168 (2006) 69-79
9. Dwivedi, D.J., Robertson, J., Fini, M.E.,West-Mays, J.A., 2006b. Requirement for MMP-9 in TGFbeta-induced anterior subcapsular cataract formation. ARVO Annual Meeting Fort Lauderdale (FL).
10. Emmert-Buck M.R., Bonner R.F., Smith P.D., Chuaqui R.F., Zhuang Z., Goldstein S.R., Weiss R.A., and Liotta L.A. Laser capture microdissection. Science 274 (1996) 998-1001
11. Engsig M.T., Chen Q.J., Vu T.H., Pedersen A.C., Therkidsen B., Lund L.R., Henriksen K., Lenhard T., Foged N.T., Werb Z., et al. Matrix metalloproteinase 9 and vascular endothelial growth factor are essential for osteoclast recruitment into developing long bones. J. Cell Biol. 151 (2000) 879-889
12. Font R.L., and Brownstein S. A light and electron microscopic study of anterior subcapsular cataracts. Am. J. Ophthalmol. 78 (1974) 972-984
13. Godin D., Ivan E., Johnson C., Magid R., and Galis Z.S. Remodeling of carotid artery is associated with increased expression of matrix metalloproteinases in mouse blood flow cessation model. Circulation 102 (2000) 2861-2866
14. Hales A.M., Chamberlain C.G., and McAvoy J.W. Cataract induction in lenses cultured with transforming growth factor-beta. Investig. Ophthalmol. Vis. Sci. 36 (1995) 1709-1713
15. Hay E.D. An overview of epithelio-mesenchymal transformation. Acta Anat. (Basel) 154 (1995) 8-20
16. Hodgkinson L.M., Duncan G., Wang L., Pennington C.J., Edwards D.R., and Wormstone I.M. MMP and TIMP expression in quiescent, dividing, and differentiating human lens cells. Investig. Ophthalmol. Vis. Sci. 48 (2007) 4192-4199
17. Ichiyama T., Kajimoto M., Suenaga N., Maeba S., Matsubara T., and Furukawa S. Serum levels of matrix metalloproteinase-9 and its tissue inhibitor (TIMP-1) in acute disseminated encephalomyelitis. J. Neuroimmunol. 172 (2006) 182-186
18. Lovicu F.J., Ang S., Chorazyczewska M., and McAvoy J.W. Deregulation of lens epithelial cell proliferation and differentiation during the development of TGFbeta-induced anterior subcapsular cataract. Dev. Neurosci. 26 (2004) 446-455
19. Lovicu F.J., Schulz M.W., Hales A.M., Vincent L.N., Overbeek P.A., Chamberlain C.G., and McAvoy J.W. TGFbeta induces morphological and molecular changes similar to human anterior subcapsular cataract. Br. J. Ophthalmol. 86 (2002) 220-226
20. Maeda M., Johnson K.R., and Wheelock M.J. Cadherin switching: essential for behavioral but not morphological changes during an epithelium-to-mesenchyme transition. J. Cell Sci. 118 (2005) 873-887
21. Manes S., Llorente M., Lacalle R.A., Gomez-Mouton C., Kremer L., Mira E., and Martinez A.C. The matrix metalloproteinase-9 regulates the insulin-like growth factor-triggered autocrine response in DU-145 carcinoma cells. J. Biol. Chem. 274 (1999) 6935-6945
22. Margetts P.J., Bonniaud P., Liu L., Hoff C.M., Holmes C.J., West-Mays J.A., and Kelly M.M. Transient overexpression of TGF-{beta}1 induces epithelial mesenchymal transition in the rodent peritoneum. J. Am. Soc. Nephrol. 16 (2005) 425-436
23. McCawley L.J., and Matrisian L.M. Matrix metalloproteinases: they're not just for matrix anymore!. Curr. Opin. Cell Biol. 13 (2001) 534-540
24. Mohan R., Chintala S.K., Jung J.C., Villar W.V., McCabe F., Russo L.A., Lee Y., McCarthy B.E., Wollenberg K.R., Jester J.V., et al. Matrix metalloproteinase gelatinase B (MMP-9) coordinates and effects epithelial regeneration. J. Biol. Chem. 277 (2002) 2065-2072
25. Novotny G.E., and Pau H. Myofibroblast-like cells in human anterior capsular cataract. Virchows Arch. A Pathol. Anat. Histopathol. 404 (1984) 393-401
26. Orlichenko L.S., and Radisky D.C. Matrix metalloproteinases stimulate epithelialmesenchymal transition during tumor development. Clin. Exp. Metastasis (2008)
27. Peinado H., Portillo F., and Cano A. Transcriptional regulation of cadherins during development and carcinogenesis. Int. J. Dev. Biol. 48 (2004) 365-375
28. Shubayev V.I., and Myers R.R. Upregulation and interaction of TNFalpha and gelatinases A and B in painful peripheral nerve injury. Brain Res. 855 (2000) 83-89
29. Srinivasan Y., Lovicu F.J., and Overbeek P.A. Lens-specific expression of transforming growth factor beta1 in transgenic mice causes anterior subcapsular cataracts. J. Clin. Invest. 101 (1998) 625-634
30. Sternlicht M.D., Lochter A., Sympson C.J., Huey B., Rougier J.P., Gray J.W., Pinkel D., Bissell M.J., and Werb Z. The stromal proteinase MMP3/stromelysin-1 promotes mammary carcinogenesis. Cell 98 (1999) 137-146
31. Van den Steen P.E., Dubois B., Nelissen I., Rudd P.M., Dwek R.A., and Opdenakker G. Biochemistry and molecular biology of gelatinase B or matrix metalloproteinase-9 (MMP-9). Crit. Rev. Biochem. Mol. Biol. 37 (2002) 375-536
32. West-Mays J.A., and Pino G. Matrix metalloproteinases as mediators of primary and secondary cataracts. Exper. Rev. Ophthalmol. 2 (2007) 931-938
33. WHO, 1998. Ageing: a public health challenge. Fact sheet no. 135.
34. WHO, 2000. Blindness: vision 2020 - the global initiative for the elimination of avoidable blindness. Fact sheet no. 213.
35. Willis B.C., and Borok Z. TGF-beta-induced EMT: mechanisms and implications for fibrotic lung disease. Am. J. Physiol. Lung Cell. Mol. Physiol. 293 (2007) L525-L534
36. Wormstone I.M., Tamiya S., Anderson I., and Duncan G. TGF-beta2-induced matrix modification and cell transdifferentiation in the human lens capsular bag. Investig. Ophthalmol. Vis. Sci. 43 (2002) 2301-2308
37. Wormstone I.M. Posterior capsule opacification: a cell biological perspective. Exp. Eye Res. 74 3 (2002) 337-347
38. Wormstone I.M., Tamiya S., Eldred J.A., Lazaridis K., Chantry A., Reddan J.R., Anderson I., and Duncan G. Characterisation of TGF-beta2 signalling and function in a human lens cell line. Exp. Eye Res. 78 (2004) 705-714
39. Wormstone I.M., Tamiya S., Marcantonio J.M., and Reddan J.R. Hepatocyte growth factor function and c-Met expression in human lens epithelial cells. Investig. Ophthalmol. Vis. Sci. 41 (2000) 4216-4222
40. Yu Q., and Stamenkovic I. Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesis. Genes Dev. 14 (2000) 163-176