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Volumn 111, Issue 50, 2014, Pages E5373-E5382

The Toll/NF-κB signaling pathway is required for epidermal wound repair in Drosophila

Author keywords

Drosophila; E cadherin; Epithelial wound repair; NF B transcription factors; Toll pathway

Indexed keywords

ACTIN; F ACTIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MYOSIN; MYOSIN II; UBIQUITIN; UVOMORULIN; CADHERIN; DROSOPHILA PROTEIN; TL PROTEIN, DROSOPHILA; TOLL LIKE RECEPTOR;

EID: 84918594063     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1408224111     Document Type: Article
Times cited : (46)

References (48)
  • 1
    • 0026452888 scopus 로고
    • Actin cables and epidermal movement in embryonic wound healing
    • Martin P, Lewis J (1992) Actin cables and epidermal movement in embryonic wound healing. Nature 360(6400):179-183.
    • (1992) Nature , vol.360 , Issue.6400 , pp. 179-183
    • Martin, P.1    Lewis, J.2
  • 2
    • 0034678354 scopus 로고    scopus 로고
    • Multiple forces contribute to cell sheet morphogenesis for dorsal closure in Drosophila
    • Kiehart DP, Galbraith CG, Edwards KA, Rickoll WL, Montague RA (2000) Multiple forces contribute to cell sheet morphogenesis for dorsal closure in Drosophila. J Cell Biol 149(2):471-490.
    • (2000) J Cell Biol , vol.149 , Issue.2 , pp. 471-490
    • Kiehart, D.P.1    Galbraith, C.G.2    Edwards, K.A.3    Rickoll, W.L.4    Montague, R.A.5
  • 4
    • 34848865857 scopus 로고    scopus 로고
    • Transcriptional control of wound repair
    • Schäfer M, Werner S (2007) Transcriptional control of wound repair. Annu Rev Cell Dev Biol 23:69-92.
    • (2007) Annu Rev Cell Dev Biol , vol.23 , pp. 69-92
    • Schäfer, M.1    Werner, S.2
  • 5
    • 17244367891 scopus 로고    scopus 로고
    • An epidermal barrier wound repair pathway in Drosophila is mediated by grainy head
    • Mace KA, Pearson JC, McGinnis W (2005) An epidermal barrier wound repair pathway in Drosophila is mediated by grainy head. Science 308(5720):381-385.
    • (2005) Science , vol.308 , Issue.5720 , pp. 381-385
    • Mace, K.A.1    Pearson, J.C.2    McGinnis, W.3
  • 6
    • 20244389223 scopus 로고    scopus 로고
    • A homolog of Drosophila grainy head is essential for epidermal integrity in mice
    • Ting SB, et al. (2005) A homolog of Drosophila grainy head is essential for epidermal integrity in mice. Science 308(5720):411-413.
    • (2005) Science , vol.308 , Issue.5720 , pp. 411-413
    • Ting, S.B.1
  • 7
    • 76649110197 scopus 로고    scopus 로고
    • Drosophila Rel proteins are central regulators of a robust, multi-organ immune network
    • Matova N, Anderson KV (2010) Drosophila Rel proteins are central regulators of a robust, multi-organ immune network. J Cell Sci 123(Pt 4):627-633.
    • (2010) J Cell Sci , vol.123 , pp. 627-633
    • Matova, N.1    Anderson, K.V.2
  • 8
    • 33750805449 scopus 로고    scopus 로고
    • Rel/NF-kappaB double mutants reveal that cellular immunity is central to Drosophila host defense
    • Matova N, Anderson KV (2006) Rel/NF-kappaB double mutants reveal that cellular immunity is central to Drosophila host defense. Proc Natl Acad Sci USA 103(44):16424-16429.
    • (2006) Proc Natl Acad Sci USA , vol.103 , Issue.44 , pp. 16424-16429
    • Matova, N.1    Anderson, K.V.2
  • 9
    • 27644443295 scopus 로고    scopus 로고
    • Dorsoventral axis formation in the Drosophila embryo - Shaping and transducing a morphogen gradient
    • Moussian B, Roth S (2005) Dorsoventral axis formation in the Drosophila embryo - shaping and transducing a morphogen gradient. Curr Biol 15(21):R887-R899.
    • (2005) Curr Biol , vol.15 , Issue.21 , pp. R887-R899
    • Moussian, B.1    Roth, S.2
  • 10
    • 0028167111 scopus 로고
    • The spätzle gene encodes a component of the extracellular signaling pathway establishing the dorsal-ventral pattern of the Drosophila embryo
    • Morisato D, Anderson KV (1994) The spätzle gene encodes a component of the extracellular signaling pathway establishing the dorsal-ventral pattern of the Drosophila embryo. Cell 76(4):677-688.
    • (1994) Cell , vol.76 , Issue.4 , pp. 677-688
    • Morisato, D.1    Anderson, K.V.2
  • 11
    • 0028182623 scopus 로고
    • A processed form of the Spätzle protein defines dorsal-ventral polarity in the Drosophila embryo
    • Schneider DS, Jin Y, Morisato D, Anderson KV (1994) A processed form of the Spätzle protein defines dorsal-ventral polarity in the Drosophila embryo. Development 120(5):1243-1250.
    • (1994) Development , vol.120 , Issue.5 , pp. 1243-1250
    • Schneider, D.S.1    Jin, Y.2    Morisato, D.3    Anderson, K.V.4
  • 12
    • 0028916254 scopus 로고
    • Cactus protein degradation mediates Drosophila dorsal-ventral signaling
    • Belvin MP, Jin Y, Anderson KV (1995) Cactus protein degradation mediates Drosophila dorsal-ventral signaling. Genes Dev 9(7):783-793.
    • (1995) Genes Dev , vol.9 , Issue.7 , pp. 783-793
    • Belvin, M.P.1    Jin, Y.2    Anderson, K.V.3
  • 13
    • 0024834128 scopus 로고
    • A gradient of nuclear localization of the dorsal protein determines dorsoventral pattern in the Drosophila embryo
    • Roth S, Stein D, Nüsslein-Volhard C (1989) A gradient of nuclear localization of the dorsal protein determines dorsoventral pattern in the Drosophila embryo. Cell 59(6):1189-1202.
    • (1989) Cell , vol.59 , Issue.6 , pp. 1189-1202
    • Roth, S.1    Stein, D.2    Nüsslein-Volhard, C.3
  • 14
    • 0024814230 scopus 로고
    • Relocalization of the dorsal protein from the cytoplasm to the nucleus correlates with its function
    • Steward R (1989) Relocalization of the dorsal protein from the cytoplasm to the nucleus correlates with its function. Cell 59(6):1179-1188.
    • (1989) Cell , vol.59 , Issue.6 , pp. 1179-1188
    • Steward, R.1
  • 15
    • 14644399248 scopus 로고    scopus 로고
    • Gastrulation movements: The logic and the nuts and bolts
    • Leptin M (2005) Gastrulation movements: The logic and the nuts and bolts. Dev Cell 8(3):305-320.
    • (2005) Dev Cell , vol.8 , Issue.3 , pp. 305-320
    • Leptin, M.1
  • 16
    • 0036668281 scopus 로고    scopus 로고
    • Cell movements during gastrulation: Snail dependent and independent pathways
    • Ip YT, Gridley T (2002) Cell movements during gastrulation: Snail dependent and independent pathways. Curr Opin Genet Dev 12(4):423-429.
    • (2002) Curr Opin Genet Dev , vol.12 , Issue.4 , pp. 423-429
    • Ip, Y.T.1    Gridley, T.2
  • 17
    • 0024003902 scopus 로고
    • Zygotic expression and activity of the Drosophila Toll gene, a gene required maternally for embryonic dorsal-ventral pattern formation
    • Gerttula S, Jin YS, Anderson KV (1988) Zygotic expression and activity of the Drosophila Toll gene, a gene required maternally for embryonic dorsal-ventral pattern formation. Genetics 119(1):123-133.
    • (1988) Genetics , vol.119 , Issue.1 , pp. 123-133
    • Gerttula, S.1    Jin, Y.S.2    Anderson, K.V.3
  • 18
    • 0025922225 scopus 로고
    • Plasma membrane localization of the Toll protein in the syncytial Drosophila embryo: Importance of transmembrane signaling for dorsal-ventral pattern formation
    • Hashimoto C, Gerttula S, Anderson KV (1991) Plasma membrane localization of the Toll protein in the syncytial Drosophila embryo: Importance of transmembrane signaling for dorsal-ventral pattern formation. Development 111(4):1021-1028.
    • (1991) Development , vol.111 , Issue.4 , pp. 1021-1028
    • Hashimoto, C.1    Gerttula, S.2    Anderson, K.V.3
  • 19
    • 84876569552 scopus 로고    scopus 로고
    • Serine proteolytic pathway activation reveals an expanded ensemble of wound response genes in Drosophila
    • Patterson RA, et al. (2013) Serine proteolytic pathway activation reveals an expanded ensemble of wound response genes in Drosophila. PLoS ONE 8(4):e61773.
    • (2013) PLoS ONE , vol.8 , Issue.4 , pp. e61773
    • Patterson, R.A.1
  • 20
    • 0027443688 scopus 로고
    • Dif, a dorsal-related gene that mediates an immune response in Drosophila
    • Ip YT, et al. (1993) Dif, a dorsal-related gene that mediates an immune response in Drosophila. Cell 75(4):753-763.
    • (1993) Cell , vol.75 , Issue.4 , pp. 753-763
    • Ip, Y.T.1
  • 21
    • 0031860827 scopus 로고    scopus 로고
    • The Dorsal-related immunity factor (Dif) can define the dorsal-ventral axis of polarity in the Drosophila embryo
    • Stein D, Goltz JS, Jurcsak J, Stevens L (1998) The Dorsal-related immunity factor (Dif) can define the dorsal-ventral axis of polarity in the Drosophila embryo. Development 125(11):2159-2169.
    • (1998) Development , vol.125 , Issue.11 , pp. 2159-2169
    • Stein, D.1    Goltz, J.S.2    Jurcsak, J.3    Stevens, L.4
  • 22
    • 3042675136 scopus 로고    scopus 로고
    • Genetic control of epidermis differentiation in Drosophila
    • Payre F (2004) Genetic control of epidermis differentiation in Drosophila. Int J Dev Biol 48(2-3):207-215.
    • (2004) Int J Dev Biol , vol.48 , Issue.2-3 , pp. 207-215
    • Payre, F.1
  • 23
    • 74249110769 scopus 로고    scopus 로고
    • Genetic screen in Drosophila melanogaster uncovers a novel set of genes required for embryonic epithelial repair
    • Campos I, Geiger JA, Santos AC, Carlos V, Jacinto A (2010) Genetic screen in Drosophila melanogaster uncovers a novel set of genes required for embryonic epithelial repair. Genetics 184(1):129-140.
    • (2010) Genetics , vol.184 , Issue.1 , pp. 129-140
    • Campos, I.1    Geiger, J.A.2    Santos, A.C.3    Carlos, V.4    Jacinto, A.5
  • 24
    • 85006298194 scopus 로고    scopus 로고
    • Wound healing recapitulates morphogenesis in Drosophila embryos
    • Wood W, et al. (2002) Wound healing recapitulates morphogenesis in Drosophila embryos. Nat Cell Biol 4(11):907-912.
    • (2002) Nat Cell Biol , vol.4 , Issue.11 , pp. 907-912
    • Wood, W.1
  • 25
    • 84875606726 scopus 로고    scopus 로고
    • Drosophila embryos close epithelial wounds using a combination of cellular protrusions and an actomyosin purse string
    • Abreu-Blanco MT, Verboon JM, Liu R, Watts JJ, Parkhurst SM (2012) Drosophila embryos close epithelial wounds using a combination of cellular protrusions and an actomyosin purse string. J Cell Sci 125(Pt 24):5984-5997.
    • (2012) J Cell Sci , vol.125 , pp. 5984-5997
    • Abreu-Blanco, M.T.1    Verboon, J.M.2    Liu, R.3    Watts, J.J.4    Parkhurst, S.M.5
  • 26
    • 0035110623 scopus 로고    scopus 로고
    • Real-time imaging of cell-cell adherens junctions reveals that Drosophila mesoderm invagination begins with two phases of apical constriction of cells
    • Oda H, Tsukita S (2001) Real-time imaging of cell-cell adherens junctions reveals that Drosophila mesoderm invagination begins with two phases of apical constriction of cells. J Cell Sci 114(Pt 3):493-501.
    • (2001) J Cell Sci , vol.114 , pp. 493-501
    • Oda, H.1    Tsukita, S.2
  • 28
    • 84862520770 scopus 로고    scopus 로고
    • Fiji: An open-source platform for biological-image analysis
    • Schindelin J, et al. (2012) Fiji: An open-source platform for biological-image analysis. Nat Methods 9(7):676-682.
    • (2012) Nat Methods , vol.9 , Issue.7 , pp. 676-682
    • Schindelin, J.1
  • 29
    • 79961157853 scopus 로고    scopus 로고
    • Analysis of protein dynamics within the septate junction reveals a highly stable core protein complex that does not include the basolateral polarity protein Discs large
    • Oshima K, Fehon RG (2011) Analysis of protein dynamics within the septate junction reveals a highly stable core protein complex that does not include the basolateral polarity protein Discs large. J Cell Sci 124(Pt 16):2861-2871.
    • (2011) J Cell Sci , vol.124 , pp. 2861-2871
    • Oshima, K.1    Fehon, R.G.2
  • 30
    • 78650866071 scopus 로고    scopus 로고
    • NF-κB in the regulation of epithelial homeostasis and inflammation
    • Wullaert A, Bonnet MC, Pasparakis M (2011) NF-κB in the regulation of epithelial homeostasis and inflammation. Cell Res 21(1):146-158.
    • (2011) Cell Res , vol.21 , Issue.1 , pp. 146-158
    • Wullaert, A.1    Bonnet, M.C.2    Pasparakis, M.3
  • 31
    • 38349000721 scopus 로고    scopus 로고
    • Nucleocytoplasmic shuttling mediates the dynamic maintenance of nuclear Dorsal levels during Drosophila embryogenesis
    • DeLotto R, DeLotto Y, Steward R, Lippincott-Schwartz J (2007) Nucleocytoplasmic shuttling mediates the dynamic maintenance of nuclear Dorsal levels during Drosophila embryogenesis. Development 134(23):4233-4241.
    • (2007) Development , vol.134 , Issue.23 , pp. 4233-4241
    • DeLotto, R.1    DeLotto, Y.2    Steward, R.3    Lippincott-Schwartz, J.4
  • 32
    • 80755133315 scopus 로고    scopus 로고
    • A dual function of Drosophila capping protein on DE-cadherin maintains epithelial integrity and prevents JNK-mediated apoptosis
    • Jezowska B, et al. (2011) A dual function of Drosophila capping protein on DE-cadherin maintains epithelial integrity and prevents JNK-mediated apoptosis. Dev Biol 360(1):143-159.
    • (2011) Dev Biol , vol.360 , Issue.1 , pp. 143-159
    • Jezowska, B.1
  • 33
    • 77954517238 scopus 로고    scopus 로고
    • Regulation of cadherin-based epithelial cell adhesion by endocytosis
    • Troyanovsky SM (2009) Regulation of cadherin-based epithelial cell adhesion by endocytosis. Front Biosci (Schol Ed) 1:61-67.
    • (2009) Front Biosci (Schol Ed) , vol.1 , pp. 61-67
    • Troyanovsky, S.M.1
  • 34
    • 66349095429 scopus 로고    scopus 로고
    • Endocytosis is required for E-cadherin redistribution at mature adherens junctions
    • de Beco S, Gueudry C, Amblard F, Coscoy S (2009) Endocytosis is required for E-cadherin redistribution at mature adherens junctions. Proc Natl Acad Sci USA 106(17):7010-7015.
    • (2009) Proc Natl Acad Sci USA , vol.106 , Issue.17 , pp. 7010-7015
    • De Beco, S.1    Gueudry, C.2    Amblard, F.3    Coscoy, S.4
  • 35
    • 68949141437 scopus 로고    scopus 로고
    • Junctional trafficking and epithelial morphogenesis
    • Wirtz-Peitz F, Zallen JA (2009) Junctional trafficking and epithelial morphogenesis. Curr Opin Genet Dev 19(4):350-356.
    • (2009) Curr Opin Genet Dev , vol.19 , Issue.4 , pp. 350-356
    • Wirtz-Peitz, F.1    Zallen, J.A.2
  • 36
    • 84876705952 scopus 로고    scopus 로고
    • The regulation and functional impact of actin assembly at cadherin cell-cell adhesions
    • Michael M, Yap AS (2013) The regulation and functional impact of actin assembly at cadherin cell-cell adhesions. Semin Cell Dev Biol 24(4):298-307.
    • (2013) Semin Cell Dev Biol , vol.24 , Issue.4 , pp. 298-307
    • Michael, M.1    Yap, A.S.2
  • 37
    • 0030217951 scopus 로고    scopus 로고
    • Threshold responses to the dorsal regulatory gradient and the subdivision of primary tissue territories in the Drosophila embryo
    • Rusch J, Levine M (1996) Threshold responses to the dorsal regulatory gradient and the subdivision of primary tissue territories in the Drosophila embryo. Curr Opin Genet Dev 6(4):416-423.
    • (1996) Curr Opin Genet Dev , vol.6 , Issue.4 , pp. 416-423
    • Rusch, J.1    Levine, M.2
  • 38
    • 0030595339 scopus 로고    scopus 로고
    • The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults
    • Lemaitre B, Nicolas E, Michaut L, Reichhart JM, Hoffmann JA (1996) The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell 86(6):973-983.
    • (1996) Cell , vol.86 , Issue.6 , pp. 973-983
    • Lemaitre, B.1    Nicolas, E.2    Michaut, L.3    Reichhart, J.M.4    Hoffmann, J.A.5
  • 39
    • 0033118490 scopus 로고    scopus 로고
    • Toll receptor-mediated Drosophila immune response requires Dif, an NF-kappaB factor
    • Meng X, Khanuja BS, Ip YT (1999) Toll receptor-mediated Drosophila immune response requires Dif, an NF-kappaB factor. Genes Dev 13(7):792-797.
    • (1999) Genes Dev , vol.13 , Issue.7 , pp. 792-797
    • Meng, X.1    Khanuja, B.S.2    Ip, Y.T.3
  • 40
    • 78649526394 scopus 로고    scopus 로고
    • Sterile inflammation: Sensing and reacting to damage
    • Chen GY, Nuñez G (2010) Sterile inflammation: Sensing and reacting to damage. Nat Rev Immunol 10(12):826-837.
    • (2010) Nat Rev Immunol , vol.10 , Issue.12 , pp. 826-837
    • Chen, G.Y.1    Nuñez, G.2
  • 41
    • 56349156617 scopus 로고    scopus 로고
    • Toll-like receptors in skin
    • Miller LS (2008) Toll-like receptors in skin. Adv Dermatol 24:71-87.
    • (2008) Adv Dermatol , vol.24 , pp. 71-87
    • Miller, L.S.1
  • 43
    • 0022230197 scopus 로고
    • Establishment of dorsal-ventral polarity in the Drosophila embryo: Genetic studies on the role of the Toll gene product
    • Anderson KV, Jürgens G, Nüsslein-Volhard C (1985) Establishment of dorsal-ventral polarity in the Drosophila embryo: Genetic studies on the role of the Toll gene product. Cell 42(3):779-789.
    • (1985) Cell , vol.42 , Issue.3 , pp. 779-789
    • Anderson, K.V.1    Jürgens, G.2    Nüsslein-Volhard, C.3
  • 44
    • 0029880967 scopus 로고    scopus 로고
    • Shotgun encodes Drosophila E-cadherin and is preferentially required during cell rearrangement in the neurectoderm and other morphogenetically active epithelia
    • Tepass U, et al. (1996) shotgun encodes Drosophila E-cadherin and is preferentially required during cell rearrangement in the neurectoderm and other morphogenetically active epithelia. Genes Dev 10(6):672-685.
    • (1996) Genes Dev , vol.10 , Issue.6 , pp. 672-685
    • Tepass, U.1
  • 45
    • 0036743611 scopus 로고    scopus 로고
    • New fluorescent protein reporters for use with the Drosophila Gal4 expression system and for vital detection of balancer chromosomes
    • Halfon MS, et al. (2002) New fluorescent protein reporters for use with the Drosophila Gal4 expression system and for vital detection of balancer chromosomes. Genesis 34(1-2):135-138.
    • (2002) Genesis , vol.34 , Issue.1-2 , pp. 135-138
    • Halfon, M.S.1
  • 46
    • 0742270614 scopus 로고    scopus 로고
    • Reassessing the role and dynamics of nonmuscle myosin II during furrow formation in early Drosophila embryos
    • Royou A, Field C, Sisson JC, Sullivan W, Karess R (2004) Reassessing the role and dynamics of nonmuscle myosin II during furrow formation in early Drosophila embryos. Mol Biol Cell 15(2):838-850.
    • (2004) Mol Biol Cell , vol.15 , Issue.2 , pp. 838-850
    • Royou, A.1    Field, C.2    Sisson, J.C.3    Sullivan, W.4    Karess, R.5
  • 47
    • 40949109632 scopus 로고    scopus 로고
    • Dynamic analysis of filopodial interactions during the zippering phase of Drosophila dorsal closure
    • Millard TH, Martin P (2008) Dynamic analysis of filopodial interactions during the zippering phase of Drosophila dorsal closure. Development 135(4):621-626.
    • (2008) Development , vol.135 , Issue.4 , pp. 621-626
    • Millard, T.H.1    Martin, P.2


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