A high-fat diet suppresses de novo lipogenesis and desaturation but not elongation and triglyceride synthesis in mice

Journal of Lipid Research

Volumn 55, Issue 12, 2014, Pages 2541-2553

  Duarte, Joao A G ^a,c   Carvalho, Filipa ^c   Pearson, Mackenzie ^a   Horton, Jay D ^b   Browning, Jeffrey D ^a,b   Jones, John G ^c   Burgess, Shawn C ^a,b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

Adipose; Lipid metabolism; Lipidomics; Liver; Nuclear magnetic resonance; Obesity

Indexed keywords

TRIACYLGLYCEROL; ACYL COENZYME A DESATURASE; DEUTERIUM; FATTY ACID SYNTHASE; SREBF1 PROTEIN, MOUSE; STEROL REGULATORY ELEMENT BINDING PROTEIN 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHOLESTEROL ESTERIFICATION; CONTROLLED STUDY; FATTY ACID ANALYSIS; FATTY ACID DESATURATION; FATTY ACID ELONGATION; FATTY LIVER; HYPERGLYCEMIA; HYPERINSULINEMIA; INSULIN RESISTANCE; LIPID DIET; LIPIDOMICS; LIPOGENESIS; MALE; MOUSE; NONHUMAN; OBESITY; PROTON NUCLEAR MAGNETIC RESONANCE; ADVERSE EFFECTS; ANIMAL; C57BL MOUSE; CROSS BREEDING; DBA MOUSE; DOWN REGULATION; ENZYMOLOGY; ESTERIFICATION; GENETICS; LIVER; METABOLISM; NON-ALCOHOLIC FATTY LIVER DISEASE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; TRANSGENIC MOUSE; UPREGULATION; WHITE ADIPOSE TISSUE;

ADIPOSE TISSUE, WHITE; ANIMALS; CROSSES, GENETIC; DEUTERIUM; DIET, HIGH-FAT; DOWN-REGULATION; ESTERIFICATION; FATTY ACID DESATURASES; FATTY ACID SYNTHASES; INSULIN RESISTANCE; LIPOGENESIS; LIVER; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MICE, INBRED C57BL; MICE, INBRED DBA; MICE, TRANSGENIC; NON-ALCOHOLIC FATTY LIVER DISEASE; OBESITY; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; TRIGLYCERIDES; UP-REGULATION;

EID: 84918577122     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M052308     Document Type: Article

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