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Volumn 57, Issue , 2015, Pages 155-165

Behavioral alterations in rat offspring following maternal immune activation and ELR-CXC chemokine receptor antagonism during pregnancy: Implications for neurodevelopmental psychiatric disorders

Author keywords

Crossmodal memory; Interleukin 8; Polyi:C; Schizophrenia; Set shifting

Indexed keywords

CHEMOKINE RECEPTOR ANTAGONIST; CXCL1 CHEMOKINE; CXCL2 CHEMOKINE; G 31P; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 6; POLYINOSINIC POLYCYTIDYLIC ACID; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; CHEMOKINE RECEPTOR CXCR; CHEMOKINE RECEPTOR CXCR1; CHEMOKINE RECEPTOR CXCR2; CXCL8(3-73)K11R,G31P; INTERLEUKIN 8; PEPTIDE FRAGMENT;

EID: 84918560994     PISSN: 02785846     EISSN: 18784216     Source Type: Journal    
DOI: 10.1016/j.pnpbp.2014.11.002     Document Type: Article
Times cited : (57)

References (76)
  • 3
    • 84862208120 scopus 로고    scopus 로고
    • Maternal immune activation by poly I:C induces expression of cytokines IL-1beta and IL-13, chemokine MCP-1 and colony stimulating factor VEGF in fetal mouse brain
    • Arrode-Bruses G., Bruses J.L. Maternal immune activation by poly I:C induces expression of cytokines IL-1beta and IL-13, chemokine MCP-1 and colony stimulating factor VEGF in fetal mouse brain. J Neuroinflammation 2012, 9:83.
    • (2012) J Neuroinflammation , vol.9 , pp. 83
    • Arrode-Bruses, G.1    Bruses, J.L.2
  • 4
    • 32844463928 scopus 로고    scopus 로고
    • The role of cytokines in mediating effects of prenatal infection on the fetus: implications for schizophrenia
    • Ashdown H., Dumont Y., Ng M., Poole S., Boksa P., Luheshi G.N. The role of cytokines in mediating effects of prenatal infection on the fetus: implications for schizophrenia. Mol Psychiatry 2006, 11:47-55.
    • (2006) Mol Psychiatry , vol.11 , pp. 47-55
    • Ashdown, H.1    Dumont, Y.2    Ng, M.3    Poole, S.4    Boksa, P.5    Luheshi, G.N.6
  • 6
    • 33947302270 scopus 로고    scopus 로고
    • Recognition memory for objects, place, and temporal order: a disconnection analysis of the role of the medial prefrontal cortex and perirhinal cortex
    • Barker G.R., Bird F., Alexander V., Warburton E.C. Recognition memory for objects, place, and temporal order: a disconnection analysis of the role of the medial prefrontal cortex and perirhinal cortex. J Neurosci 2007, 27:2948-2957.
    • (2007) J Neurosci , vol.27 , pp. 2948-2957
    • Barker, G.R.1    Bird, F.2    Alexander, V.3    Warburton, E.C.4
  • 7
    • 0034891977 scopus 로고    scopus 로고
    • Human studies of prepulse inhibition of startle: normal subjects, patient groups, and pharmacological studies
    • Braff D.L., Geyer M.A., Swerdlow N.R. Human studies of prepulse inhibition of startle: normal subjects, patient groups, and pharmacological studies. Psychopharmacology (Berl) 2001, 156:234-258.
    • (2001) Psychopharmacology (Berl) , vol.156 , pp. 234-258
    • Braff, D.L.1    Geyer, M.A.2    Swerdlow, N.R.3
  • 8
    • 79851510670 scopus 로고    scopus 로고
    • Individual differences in maternal response to immune challenge predict offspring behavior: contribution of environmental factors
    • Bronson S.L., Ahlbrand R., Horn P.S., Kern J.R., Richtand N.M. Individual differences in maternal response to immune challenge predict offspring behavior: contribution of environmental factors. Behav Brain Res 2011, 220:55-64.
    • (2011) Behav Brain Res , vol.220 , pp. 55-64
    • Bronson, S.L.1    Ahlbrand, R.2    Horn, P.S.3    Kern, J.R.4    Richtand, N.M.5
  • 9
    • 2442593823 scopus 로고    scopus 로고
    • Elevated maternal interleukin-8 levels and risk of schizophrenia in adult offspring
    • Brown A.S., Hooton J., Schaefer C.A., Zhang H., Petkova E., Babulas V., et al. Elevated maternal interleukin-8 levels and risk of schizophrenia in adult offspring. Am J Psychiatry 2004, 161:889-895.
    • (2004) Am J Psychiatry , vol.161 , pp. 889-895
    • Brown, A.S.1    Hooton, J.2    Schaefer, C.A.3    Zhang, H.4    Petkova, E.5    Babulas, V.6
  • 10
    • 79959409441 scopus 로고    scopus 로고
    • Placental TNF-α signaling in illness-induced complications of pregnancy
    • Carpentier P.A., Dingman A.L., Palmer T.D. Placental TNF-α signaling in illness-induced complications of pregnancy. Am J Pathol 2011, 178:2802-2810.
    • (2011) Am J Pathol , vol.178 , pp. 2802-2810
    • Carpentier, P.A.1    Dingman, A.L.2    Palmer, T.D.3
  • 11
    • 80054829697 scopus 로고    scopus 로고
    • AMPA receptor endocytosis in rat perirhinal cortex underlies retrieval of object memory
    • Cazakoff B.N., Howland J.G. AMPA receptor endocytosis in rat perirhinal cortex underlies retrieval of object memory. Learn Mem 2011, 18:688-692.
    • (2011) Learn Mem , vol.18 , pp. 688-692
    • Cazakoff, B.N.1    Howland, J.G.2
  • 12
    • 0036954322 scopus 로고    scopus 로고
    • Chemokine receptors and neural function
    • Cho C., Miller R.J. Chemokine receptors and neural function. J Neurovirol 2002, 8:573-584.
    • (2002) J Neurovirol , vol.8 , pp. 573-584
    • Cho, C.1    Miller, R.J.2
  • 13
    • 70349838218 scopus 로고    scopus 로고
    • Cytokines and CNS development
    • Deverman B.E., Patterson P.H. Cytokines and CNS development. Neuron 2009, 64:61-78.
    • (2009) Neuron , vol.64 , pp. 61-78
    • Deverman, B.E.1    Patterson, P.H.2
  • 14
    • 77956825112 scopus 로고    scopus 로고
    • Abnormal long-range neural synchrony in a maternal immune activation animal model of schizophrenia
    • Dickerson D.D., Wolff A.R., Bilkey D.K. Abnormal long-range neural synchrony in a maternal immune activation animal model of schizophrenia. J Neurosci 2010, 30:12424-12431.
    • (2010) J Neurosci , vol.30 , pp. 12424-12431
    • Dickerson, D.D.1    Wolff, A.R.2    Bilkey, D.K.3
  • 15
    • 84892410541 scopus 로고    scopus 로고
    • A novel role for brain interleukin-6: facilitation of cognitive flexibility in rat orbitofrontal cortex
    • Donegan J.J., Girotti M., Weinberg M.S., Morilak D.A. A novel role for brain interleukin-6: facilitation of cognitive flexibility in rat orbitofrontal cortex. J Neurosci 2014, 34:953-962.
    • (2014) J Neurosci , vol.34 , pp. 953-962
    • Donegan, J.J.1    Girotti, M.2    Weinberg, M.S.3    Morilak, D.A.4
  • 16
    • 77955057052 scopus 로고    scopus 로고
    • Structural brain alterations in schizophrenia following fetal exposure to the inflammatory cytokine interleukin-8
    • Ellman L.M., Deicken R.F., Vinogradov S., Kremen W.S., Poole J.H., Kern D.M., et al. Structural brain alterations in schizophrenia following fetal exposure to the inflammatory cytokine interleukin-8. Schizophr Res 2010, 121:46-54.
    • (2010) Schizophr Res , vol.121 , pp. 46-54
    • Ellman, L.M.1    Deicken, R.F.2    Vinogradov, S.3    Kremen, W.S.4    Poole, J.H.5    Kern, D.M.6
  • 17
    • 79951682329 scopus 로고    scopus 로고
    • Reducing prefrontal gamma-aminobutyric acid activity induces cognitive, behavioral, and dopaminergic abnormalities that resemble schizophrenia
    • Enomoto T., Tse M.T., Floresco S.B. Reducing prefrontal gamma-aminobutyric acid activity induces cognitive, behavioral, and dopaminergic abnormalities that resemble schizophrenia. Biol Psychiatry 2011, 69:432-441.
    • (2011) Biol Psychiatry , vol.69 , pp. 432-441
    • Enomoto, T.1    Tse, M.T.2    Floresco, S.B.3
  • 18
    • 84876945142 scopus 로고    scopus 로고
    • Inflammatory cytokines and neurological and neurocognitive alterations in the course of schizophrenia
    • Fineberg A.M., Ellman L.M. Inflammatory cytokines and neurological and neurocognitive alterations in the course of schizophrenia. Biol Psychiatry 2013, 73:951-966.
    • (2013) Biol Psychiatry , vol.73 , pp. 951-966
    • Fineberg, A.M.1    Ellman, L.M.2
  • 19
    • 41949115175 scopus 로고    scopus 로고
    • Inactivation of the medial prefrontal cortex of the rat impairs strategy set-shifting, but not reversal learning, using a novel, automated procedure
    • Floresco S.B., Block A.E., Tse M.T. Inactivation of the medial prefrontal cortex of the rat impairs strategy set-shifting, but not reversal learning, using a novel, automated procedure. Behav Brain Res 2008, 190:85-96.
    • (2008) Behav Brain Res , vol.190 , pp. 85-96
    • Floresco, S.B.1    Block, A.E.2    Tse, M.T.3
  • 20
    • 69249241867 scopus 로고    scopus 로고
    • Neural circuits subserving behavioral flexibility and their relevance to schizophrenia
    • Floresco S.B., Zhang Y., Enomoto T. Neural circuits subserving behavioral flexibility and their relevance to schizophrenia. Behav Brain Res 2009, 204:396-409.
    • (2009) Behav Brain Res , vol.204 , pp. 396-409
    • Floresco, S.B.1    Zhang, Y.2    Enomoto, T.3
  • 21
    • 4644372522 scopus 로고    scopus 로고
    • The viral mimic, polyinosinic:polycytidylic acid, induces fever in rats via an interleukin-1-dependent mechanism. Am. J. Physiol Regul. Integr
    • Fortier M.E., Kent S., Ashdown H., Poole S., Boksa P., Luheshi G.N. The viral mimic, polyinosinic:polycytidylic acid, induces fever in rats via an interleukin-1-dependent mechanism. Am. J. Physiol Regul. Integr. Am J Physiol Regul Integr Comp Physiol 2004, 287:R759-R766.
    • (2004) Am J Physiol Regul Integr Comp Physiol , vol.287 , pp. R759-R766
    • Fortier, M.E.1    Kent, S.2    Ashdown, H.3    Poole, S.4    Boksa, P.5    Luheshi, G.N.6
  • 22
    • 34250196472 scopus 로고    scopus 로고
    • Effects of prenatal infection on prepulse inhibition in the rat depend on the nature of the infectious agent and the stage of pregnancy
    • Fortier M.E., Luheshi G.N., Boksa P. Effects of prenatal infection on prepulse inhibition in the rat depend on the nature of the infectious agent and the stage of pregnancy. Behav Brain Res 2007, 181:270-277.
    • (2007) Behav Brain Res , vol.181 , pp. 270-277
    • Fortier, M.E.1    Luheshi, G.N.2    Boksa, P.3
  • 23
    • 84877352822 scopus 로고    scopus 로고
    • Maternal immune activation causes age- and region-specific changes in brain cytokines in offspring throughout development
    • Garay P.A., Hsiao E.Y., Patterson P.H., McAllister A.K. Maternal immune activation causes age- and region-specific changes in brain cytokines in offspring throughout development. Brain Behav Immun 2013, 31:54-68.
    • (2013) Brain Behav Immun , vol.31 , pp. 54-68
    • Garay, P.A.1    Hsiao, E.Y.2    Patterson, P.H.3    McAllister, A.K.4
  • 24
    • 2942683385 scopus 로고    scopus 로고
    • Prenatal infection and risk for schizophrenia: IL-1beta, IL-6, and TNFalpha inhibit cortical neuron dendrite development
    • Gilmore J.H., Fredrik J.L., Vadlamudi S., Lauder J.M. Prenatal infection and risk for schizophrenia: IL-1beta, IL-6, and TNFalpha inhibit cortical neuron dendrite development. Neuropsychopharmacology 2004, 29:1221-1229.
    • (2004) Neuropsychopharmacology , vol.29 , pp. 1221-1229
    • Gilmore, J.H.1    Fredrik, J.L.2    Vadlamudi, S.3    Lauder, J.M.4
  • 25
    • 12344280393 scopus 로고    scopus 로고
    • Maternal poly I:C exposure during pregnancy regulates TNF alpha, BDNF, and NGF expression in neonatal brain and the maternal-fetal unit of the rat
    • Gilmore J.H., Jarskog L.F., Vadlamudi S. Maternal poly I:C exposure during pregnancy regulates TNF alpha, BDNF, and NGF expression in neonatal brain and the maternal-fetal unit of the rat. J Neuroimmunol 2005, 159:106-112.
    • (2005) J Neuroimmunol , vol.159 , pp. 106-112
    • Gilmore, J.H.1    Jarskog, L.F.2    Vadlamudi, S.3
  • 26
    • 28844452023 scopus 로고    scopus 로고
    • The combined CXCR1/CXCR2 antagonist CXCL8(3-74)K11R/G31P blocks neutrophil infiltration, pyrexia, and pulmonary vascular pathology in endotoxemic animals
    • Gordon J.R., Li F., Zhang X., Wang W., Zhao X., Nayyar A. The combined CXCR1/CXCR2 antagonist CXCL8(3-74)K11R/G31P blocks neutrophil infiltration, pyrexia, and pulmonary vascular pathology in endotoxemic animals. J Leukoc Biol 2005, 78:1265-1272.
    • (2005) J Leukoc Biol , vol.78 , pp. 1265-1272
    • Gordon, J.R.1    Li, F.2    Zhang, X.3    Wang, W.4    Zhao, X.5    Nayyar, A.6
  • 27
    • 68949207045 scopus 로고    scopus 로고
    • Amelioration of pathology by ELR-CXC chemokine antagonism in a swine model of airway endotoxin exposure
    • Gordon J.R., Zhang X., Li F., Nayyar A., Zhao X. Amelioration of pathology by ELR-CXC chemokine antagonism in a swine model of airway endotoxin exposure. J Agromed 2009, 14:235-241.
    • (2009) J Agromed , vol.14 , pp. 235-241
    • Gordon, J.R.1    Zhang, X.2    Li, F.3    Nayyar, A.4    Zhao, X.5
  • 28
    • 79955905462 scopus 로고    scopus 로고
    • Maternal immune activation impairs reversal learning and increases serum tumor necrosis factor-alpha in offspring
    • Han X., Li N., Meng Q., Shao F., Wang W. Maternal immune activation impairs reversal learning and increases serum tumor necrosis factor-alpha in offspring. Neuropsychobiology 2011, 64:9-14.
    • (2011) Neuropsychobiology , vol.64 , pp. 9-14
    • Han, X.1    Li, N.2    Meng, Q.3    Shao, F.4    Wang, W.5
  • 29
    • 9644255809 scopus 로고    scopus 로고
    • Delayed onset of prepulse inhibition deficits following kainic acid treatment on postnatal day 7 in rats
    • Howland J.G., Hannesson D.K., Phillips A.G. Delayed onset of prepulse inhibition deficits following kainic acid treatment on postnatal day 7 in rats. Eur J Neurosci 2004, 20:2639-2648.
    • (2004) Eur J Neurosci , vol.20 , pp. 2639-2648
    • Howland, J.G.1    Hannesson, D.K.2    Phillips, A.G.3
  • 30
    • 84855555397 scopus 로고    scopus 로고
    • Altered object-in-place recognition memory, prepulse inhibition, and locomotor activity in the offspring of rats exposed to a viral mimetic during pregnancy
    • Howland J.G., Cazakoff B.N., Zhang Y. Altered object-in-place recognition memory, prepulse inhibition, and locomotor activity in the offspring of rats exposed to a viral mimetic during pregnancy. Neuroscience 2012, 201:184-198.
    • (2012) Neuroscience , vol.201 , pp. 184-198
    • Howland, J.G.1    Cazakoff, B.N.2    Zhang, Y.3
  • 31
    • 79954718560 scopus 로고    scopus 로고
    • Activation of the maternal immune system induces endocrine changes in the placenta via IL-6
    • Hsiao E.Y., Patterson P.H. Activation of the maternal immune system induces endocrine changes in the placenta via IL-6. Brain Behav Immun 2011, 25:604-615.
    • (2011) Brain Behav Immun , vol.25 , pp. 604-615
    • Hsiao, E.Y.1    Patterson, P.H.2
  • 32
    • 84865235322 scopus 로고    scopus 로고
    • Severe cross-modal object recognition deficits in rats treated sub-chronically with NMDA receptor antagonists are reversed by systemic nicotine: implications for abnormal multisensory integration in schizophrenia
    • Jacklin D.L., Goel A., Clementino K.J., Hall A.W., Talpos J.C., Winters B.D. Severe cross-modal object recognition deficits in rats treated sub-chronically with NMDA receptor antagonists are reversed by systemic nicotine: implications for abnormal multisensory integration in schizophrenia. Neuropsychopharmacology 2012, 37:2322-2331.
    • (2012) Neuropsychopharmacology , vol.37 , pp. 2322-2331
    • Jacklin, D.L.1    Goel, A.2    Clementino, K.J.3    Hall, A.W.4    Talpos, J.C.5    Winters, B.D.6
  • 33
    • 80052843448 scopus 로고    scopus 로고
    • Fever and inflammatory cytokine response in rats injected subcutaneously with viral double-stranded RNA analog, polyinosinic:polycytidylic acid (Poly-I:C)
    • Kamerman P., Skosana M., Loram L., Mitchell B., Weber J. Fever and inflammatory cytokine response in rats injected subcutaneously with viral double-stranded RNA analog, polyinosinic:polycytidylic acid (Poly-I:C). J Therm Biol 2011, 35:397-402.
    • (2011) J Therm Biol , vol.35 , pp. 397-402
    • Kamerman, P.1    Skosana, M.2    Loram, L.3    Mitchell, B.4    Weber, J.5
  • 34
    • 84879993839 scopus 로고    scopus 로고
    • Mapping brain regions in which deep brain stimulation affects schizophrenia-like behavior in two rat models of schizophrenia
    • Klein J., Hadar R., Gotz T., Manner A., Eberhardt C., Baldassarri J., et al. Mapping brain regions in which deep brain stimulation affects schizophrenia-like behavior in two rat models of schizophrenia. Brain Stimul 2013, 6:490-499.
    • (2013) Brain Stimul , vol.6 , pp. 490-499
    • Klein, J.1    Hadar, R.2    Gotz, T.3    Manner, A.4    Eberhardt, C.5    Baldassarri, J.6
  • 35
    • 0036297593 scopus 로고    scopus 로고
    • Glucocorticoid hormones and early brain development in schizophrenia
    • Koenig J.I., Kirkpatrick B., Lee P. Glucocorticoid hormones and early brain development in schizophrenia. Neuropsychopharmacology 2002, 27:309-318.
    • (2002) Neuropsychopharmacology , vol.27 , pp. 309-318
    • Koenig, J.I.1    Kirkpatrick, B.2    Lee, P.3
  • 36
    • 68949184845 scopus 로고    scopus 로고
    • Discrimination learning, reversal, and set-shifting in first-episode schizophrenia: stability over six years and specific associations with medication type and disorganization syndrome
    • Leeson V.C., Robbins T.W., Matheson E., Hutton S.B., Ron M.A., Barnes T.R., et al. Discrimination learning, reversal, and set-shifting in first-episode schizophrenia: stability over six years and specific associations with medication type and disorganization syndrome. Biol Psychiatry 2009, 66:586-593.
    • (2009) Biol Psychiatry , vol.66 , pp. 586-593
    • Leeson, V.C.1    Robbins, T.W.2    Matheson, E.3    Hutton, S.B.4    Ron, M.A.5    Barnes, T.R.6
  • 37
    • 0036876388 scopus 로고    scopus 로고
    • (3-73)K11R/G31P antagonizes the neutrophil chemoattractants present in pasteurellosis and mastitis lesions and abrogates neutrophil influx into intradermal endotoxin challenge sites in vivo
    • (3-73)K11R/G31P antagonizes the neutrophil chemoattractants present in pasteurellosis and mastitis lesions and abrogates neutrophil influx into intradermal endotoxin challenge sites in vivo. Vet Immunol Immunopathol 2002, 90:65-77.
    • (2002) Vet Immunol Immunopathol , vol.90 , pp. 65-77
    • Li, F.1    Zhang, X.2    Mizzi, C.3    Gordon, J.R.4
  • 38
    • 67749147581 scopus 로고    scopus 로고
    • Prenatal immune challenge is an environmental risk factor for brain and behavior change relevant to schizophrenia: evidence from MRI in a mouse model
    • Li Q., Cheung C., Wei R., Hui E.S., Feldon J., Meyer U., et al. Prenatal immune challenge is an environmental risk factor for brain and behavior change relevant to schizophrenia: evidence from MRI in a mouse model. PLoS One 2009, 4:e6354.
    • (2009) PLoS One , vol.4 , pp. e6354
    • Li, Q.1    Cheung, C.2    Wei, R.3    Hui, E.S.4    Feldon, J.5    Meyer, U.6
  • 39
    • 7544237332 scopus 로고    scopus 로고
    • Measurement and treatment research to improve cognition in schizophrenia: NIMH MATRICS initiative to support the development of agents for improving cognition in schizophrenia
    • Marder S.R., Fenton W. Measurement and treatment research to improve cognition in schizophrenia: NIMH MATRICS initiative to support the development of agents for improving cognition in schizophrenia. Schizophr Res 2004, 72:5-9.
    • (2004) Schizophr Res , vol.72 , pp. 5-9
    • Marder, S.R.1    Fenton, W.2
  • 40
    • 84898539073 scopus 로고    scopus 로고
    • Minocycline rescues decrease in neurogenesis, increase in microglia cytokines and deficits in sensorimotor gating in an animal model of schizophrenia
    • Mattei D., Djodari-Irani A., Hadar R., Pelz A., de Cossio L.F., Goetz T., et al. Minocycline rescues decrease in neurogenesis, increase in microglia cytokines and deficits in sensorimotor gating in an animal model of schizophrenia. Brain Behav Immun 2014, 38:175-184.
    • (2014) Brain Behav Immun , vol.38 , pp. 175-184
    • Mattei, D.1    Djodari-Irani, A.2    Hadar, R.3    Pelz, A.4    de Cossio, L.F.5    Goetz, T.6
  • 41
    • 84856095635 scopus 로고    scopus 로고
    • To poly(I:C) or not to poly(I:C): advancing preclinical schizophrenia research through the use of prenatal immune activation models
    • Meyer U., Feldon J. To poly(I:C) or not to poly(I:C): advancing preclinical schizophrenia research through the use of prenatal immune activation models. Neuropharmacology 2012, 62:1308-1321.
    • (2012) Neuropharmacology , vol.62 , pp. 1308-1321
    • Meyer, U.1    Feldon, J.2
  • 42
    • 33646831799 scopus 로고    scopus 로고
    • Immunological stress at the maternal-foetal interface: a link between neurodevelopment and adult psychopathology
    • Meyer U., Feldon J., Schedlowski M., Yee B.K. Immunological stress at the maternal-foetal interface: a link between neurodevelopment and adult psychopathology. Brain Behav Immun 2006, 20:378-388.
    • (2006) Brain Behav Immun , vol.20 , pp. 378-388
    • Meyer, U.1    Feldon, J.2    Schedlowski, M.3    Yee, B.K.4
  • 43
    • 33646926705 scopus 로고    scopus 로고
    • The time of prenatal immune challenge determines the specificity of inflammation-mediated brain and behavioral pathology
    • Meyer U., Nyffeler M., Engler A., Urwyler A., Schedlowski M., Knuesel I., et al. The time of prenatal immune challenge determines the specificity of inflammation-mediated brain and behavioral pathology. J Neurosci 2006, 26:4752-4762.
    • (2006) J Neurosci , vol.26 , pp. 4752-4762
    • Meyer, U.1    Nyffeler, M.2    Engler, A.3    Urwyler, A.4    Schedlowski, M.5    Knuesel, I.6
  • 44
    • 67649464224 scopus 로고    scopus 로고
    • In-vivo rodent models for the experimental investigation of prenatal immune activation effects in neurodevelopmental brain disorders
    • Meyer U., Feldon J., Fatemi S.H. In-vivo rodent models for the experimental investigation of prenatal immune activation effects in neurodevelopmental brain disorders. Neurosci Biobehav Rev 2009, 33:1061-1079.
    • (2009) Neurosci Biobehav Rev , vol.33 , pp. 1061-1079
    • Meyer, U.1    Feldon, J.2    Fatemi, S.H.3
  • 45
    • 77953179882 scopus 로고    scopus 로고
    • Evaluating early preventive antipsychotic and antidepressant drug treatment in an infection-based neurodevelopmental mouse model of schizophrenia
    • Meyer U., Spoerri E., Yee B.K., Schwarz M.J., Feldon J. Evaluating early preventive antipsychotic and antidepressant drug treatment in an infection-based neurodevelopmental mouse model of schizophrenia. Schizophr Bull 2010, 36:607-623.
    • (2010) Schizophr Bull , vol.36 , pp. 607-623
    • Meyer, U.1    Spoerri, E.2    Yee, B.K.3    Schwarz, M.J.4    Feldon, J.5
  • 46
    • 78650359084 scopus 로고    scopus 로고
    • The neuropathological contribution of prenatal inflammation to schizophrenia
    • Meyer U., Weiner I., McAlonan G.M., Feldon J. The neuropathological contribution of prenatal inflammation to schizophrenia. Expert Rev Neurother 2011, 11:29-32.
    • (2011) Expert Rev Neurother , vol.11 , pp. 29-32
    • Meyer, U.1    Weiner, I.2    McAlonan, G.M.3    Feldon, J.4
  • 47
    • 0033594976 scopus 로고    scopus 로고
    • Comparison of set-shifting ability in patients with chronic schizophrenia and frontal lobe damage
    • Pantelis C., Barber F.Z., Barnes T.R., Nelson H.E., Owen A.M., Robbins T.W. Comparison of set-shifting ability in patients with chronic schizophrenia and frontal lobe damage. Schizophr Res 1999, 37:251-270.
    • (1999) Schizophr Res , vol.37 , pp. 251-270
    • Pantelis, C.1    Barber, F.Z.2    Barnes, T.R.3    Nelson, H.E.4    Owen, A.M.5    Robbins, T.W.6
  • 48
    • 67749114055 scopus 로고    scopus 로고
    • Immune involvement in schizophrenia and autism: etiology, pathology and animal models
    • Patterson P.H. Immune involvement in schizophrenia and autism: etiology, pathology and animal models. Behav Brain Res 2009, 204:313-321.
    • (2009) Behav Brain Res , vol.204 , pp. 313-321
    • Patterson, P.H.1
  • 49
    • 79959964671 scopus 로고    scopus 로고
    • Maternal infection and immune involvement in autism
    • Patterson P.H. Maternal infection and immune involvement in autism. Trends Mol Med 2011, 17:389-394.
    • (2011) Trends Mol Med , vol.17 , pp. 389-394
    • Patterson, P.H.1
  • 50
    • 84856102897 scopus 로고    scopus 로고
    • Tracing the development of psychosis and its prevention: what can be learned from animal models
    • Piontkewitz Y., Arad M., Weiner I. Tracing the development of psychosis and its prevention: what can be learned from animal models. Neuropharmacology 2012, 62:1273-1289.
    • (2012) Neuropharmacology , vol.62 , pp. 1273-1289
    • Piontkewitz, Y.1    Arad, M.2    Weiner, I.3
  • 51
    • 0036948779 scopus 로고    scopus 로고
    • CXC chemokine receptors in the central nervous system: role in cerebellar neuromodulation and development
    • Ragozzino D. CXC chemokine receptors in the central nervous system: role in cerebellar neuromodulation and development. J Neurovirol 2002, 8:559-572.
    • (2002) J Neurovirol , vol.8 , pp. 559-572
    • Ragozzino, D.1
  • 52
    • 78951475437 scopus 로고    scopus 로고
    • Dysregulation of chemo-cytokine production in schizophrenic patients versus healthy controls
    • Reale M., Patruno A., De Lutiis M.A., Pesce M., Felaco M., Di G.M., et al. Dysregulation of chemo-cytokine production in schizophrenic patients versus healthy controls. BMC Neurosci 2011, 12:13.
    • (2011) BMC Neurosci , vol.12 , pp. 13
    • Reale, M.1    Patruno, A.2    De Lutiis, M.A.3    Pesce, M.4    Felaco, M.5    Di, G.M.6
  • 54
    • 84900389904 scopus 로고    scopus 로고
    • Heightened fear in response to a safety cue and extinguished fear cue in a rat model of maternal immune activation
    • Sangha S., Greba Q., Robinson P.D., Ballendine S.A., Howland J.G. Heightened fear in response to a safety cue and extinguished fear cue in a rat model of maternal immune activation. Front Behav Neurosci 2014, 8:168.
    • (2014) Front Behav Neurosci , vol.8 , pp. 168
    • Sangha, S.1    Greba, Q.2    Robinson, P.D.3    Ballendine, S.A.4    Howland, J.G.5
  • 55
    • 84888136844 scopus 로고    scopus 로고
    • Enhanced hippocampal neuronal excitability and LTP persistence associated with reduced behavioral flexibility in the maternal immune activation model of schizophrenia
    • Savanthrapadian S., Wolff A.R., Logan B.J., Eckert M.J., Bilkey D.K., Abraham W.C. Enhanced hippocampal neuronal excitability and LTP persistence associated with reduced behavioral flexibility in the maternal immune activation model of schizophrenia. Hippocampus 2013, 23:1395-1409.
    • (2013) Hippocampus , vol.23 , pp. 1395-1409
    • Savanthrapadian, S.1    Wolff, A.R.2    Logan, B.J.3    Eckert, M.J.4    Bilkey, D.K.5    Abraham, W.C.6
  • 56
    • 0037218688 scopus 로고    scopus 로고
    • Maternal influenza infection causes marked behavioral and pharmacological changes in the offspring
    • Shi L., Fatemi S.H., Sidwell R.W., Patterson P.H. Maternal influenza infection causes marked behavioral and pharmacological changes in the offspring. J Neurosci 2003, 23:297-302.
    • (2003) J Neurosci , vol.23 , pp. 297-302
    • Shi, L.1    Fatemi, S.H.2    Sidwell, R.W.3    Patterson, P.H.4
  • 57
    • 35148872226 scopus 로고    scopus 로고
    • Maternal immune activation alters fetal brain development through interleukin-6
    • Smith S.E., Li J., Garbett K., Mirnics K., Patterson P.H. Maternal immune activation alters fetal brain development through interleukin-6. J Neurosci 2007, 27:10695-10702.
    • (2007) J Neurosci , vol.27 , pp. 10695-10702
    • Smith, S.E.1    Li, J.2    Garbett, K.3    Mirnics, K.4    Patterson, P.H.5
  • 58
    • 85067746812 scopus 로고    scopus 로고
    • The nuclear factor-κB inhibitor pyrrolidine dithiocarbamate reduces polyinosinic-polycytidilic acid-induced immune response in pregnant rats and the behavioral defects of their adult offspring
    • Song Z., Wenqiang L., Yongfeng Y., Zhao J., Jiang C., Li W., et al. The nuclear factor-κB inhibitor pyrrolidine dithiocarbamate reduces polyinosinic-polycytidilic acid-induced immune response in pregnant rats and the behavioral defects of their adult offspring. Behav Brain Funct 2011, 7:1-9.
    • (2011) Behav Brain Funct , vol.7 , pp. 1-9
    • Song, Z.1    Wenqiang, L.2    Yongfeng, Y.3    Zhao, J.4    Jiang, C.5    Li, W.6
  • 59
    • 84878959945 scopus 로고    scopus 로고
    • Deficient multisensory integration in schizophrenia: an event-related potential study
    • Stekelenburg J.J., Maes J.P., Van Gool A.R., Sitskoorn M., Vroomen J. Deficient multisensory integration in schizophrenia: an event-related potential study. Schizophr Res 2013, 147:253-261.
    • (2013) Schizophr Res , vol.147 , pp. 253-261
    • Stekelenburg, J.J.1    Maes, J.P.2    Van Gool, A.R.3    Sitskoorn, M.4    Vroomen, J.5
  • 60
    • 80053608729 scopus 로고    scopus 로고
    • Unisensory processing and multisensory integration in schizophrenia: a high-density electrical mapping study
    • Stone D.B., Urrea L.J., Aine C.J., Bustillo J.R., Clark V.P., Stephen J.M. Unisensory processing and multisensory integration in schizophrenia: a high-density electrical mapping study. Neuropsychologia 2011, 49:3178-3187.
    • (2011) Neuropsychologia , vol.49 , pp. 3178-3187
    • Stone, D.B.1    Urrea, L.J.2    Aine, C.J.3    Bustillo, J.R.4    Clark, V.P.5    Stephen, J.M.6
  • 61
    • 84896055808 scopus 로고    scopus 로고
    • Chemokines and chemokine receptors in mood disorders, schizophrenia, and cognitive impairment: A systematic review of biomarker studies
    • Stuart M.J., Baune B.T. Chemokines and chemokine receptors in mood disorders, schizophrenia, and cognitive impairment: A systematic review of biomarker studies. Neurosci Biobeha Rev 2014, 42:93-115.
    • (2014) Neurosci Biobeha Rev , vol.42 , pp. 93-115
    • Stuart, M.J.1    Baune, B.T.2
  • 62
    • 84873853820 scopus 로고    scopus 로고
    • Effects of acute restraint stress on set-shifting and reversal learning in male rats
    • Thai C.A., Zhang Y., Howland J.G. Effects of acute restraint stress on set-shifting and reversal learning in male rats. Cogn Affect Behav Neurosci 2013, 13:164-173.
    • (2013) Cogn Affect Behav Neurosci , vol.13 , pp. 164-173
    • Thai, C.A.1    Zhang, Y.2    Howland, J.G.3
  • 63
    • 0038042119 scopus 로고    scopus 로고
    • Chemokine receptors: signposts to brain development and disease
    • Tran P.B., Miller R.J. Chemokine receptors: signposts to brain development and disease. Nat Rev Neurosci 2003, 4:444-455.
    • (2003) Nat Rev Neurosci , vol.4 , pp. 444-455
    • Tran, P.B.1    Miller, R.J.2
  • 64
    • 34249291941 scopus 로고    scopus 로고
    • Probabilistic reversal learning impairments in schizophrenia: further evidence of orbitofrontal dysfunction
    • Waltz J.A., Gold J.M. Probabilistic reversal learning impairments in schizophrenia: further evidence of orbitofrontal dysfunction. Schizophr Res 2007, 93:296-303.
    • (2007) Schizophr Res , vol.93 , pp. 296-303
    • Waltz, J.A.1    Gold, J.M.2
  • 65
    • 77952569813 scopus 로고    scopus 로고
    • Cytokine hypothesis of schizophrenia pathogenesis: evidence from human studies and animal models
    • Watanabe Y., Someya T., Nawa H. Cytokine hypothesis of schizophrenia pathogenesis: evidence from human studies and animal models. Psychiatry Clin Neurosci 2010, 64:217-230.
    • (2010) Psychiatry Clin Neurosci , vol.64 , pp. 217-230
    • Watanabe, Y.1    Someya, T.2    Nawa, H.3
  • 66
    • 84876577683 scopus 로고    scopus 로고
    • CXCR1/CXCR2 antagonism is effective in pulmonary defense against Klebsiella pneumoniae infection
    • Wei J., Peng J., Wang B., Qu H., Wang S., Faisal A., et al. CXCR1/CXCR2 antagonism is effective in pulmonary defense against Klebsiella pneumoniae infection. Biomed Res Int 2013, 2013:720975.
    • (2013) Biomed Res Int , vol.2013 , pp. 720975
    • Wei, J.1    Peng, J.2    Wang, B.3    Qu, H.4    Wang, S.5    Faisal, A.6
  • 67
    • 77955274088 scopus 로고    scopus 로고
    • Reduced multisensory integration in patients with schizophrenia on a target detection task
    • Williams L.E., Light G.A., Braff D.L., Ramachandran V.S. Reduced multisensory integration in patients with schizophrenia on a target detection task. Neuropsychologia 2010, 48:3128-3136.
    • (2010) Neuropsychologia , vol.48 , pp. 3128-3136
    • Williams, L.E.1    Light, G.A.2    Braff, D.L.3    Ramachandran, V.S.4
  • 68
    • 77951803633 scopus 로고    scopus 로고
    • A distributed cortical representation underlies crossmodal object recognition in rats
    • Winters B.D., Reid J.M. A distributed cortical representation underlies crossmodal object recognition in rats. J Neurosci 2010, 30:6253-6261.
    • (2010) J Neurosci , vol.30 , pp. 6253-6261
    • Winters, B.D.1    Reid, J.M.2
  • 69
    • 41949121162 scopus 로고    scopus 로고
    • Immune activation during mid-gestation disrupts sensorimotor gating in rat offspring
    • Wolff A.R., Bilkey D.K. Immune activation during mid-gestation disrupts sensorimotor gating in rat offspring. Behav Brain Res 2008, 190:156-159.
    • (2008) Behav Brain Res , vol.190 , pp. 156-159
    • Wolff, A.R.1    Bilkey, D.K.2
  • 70
    • 77953916423 scopus 로고    scopus 로고
    • The maternal immune activation (MIA) model of schizophrenia produces pre-pulse inhibition (PPI) deficits in both juvenile and adult rats but these effects are not associated with maternal weight loss
    • Wolff A.R., Bilkey D.K. The maternal immune activation (MIA) model of schizophrenia produces pre-pulse inhibition (PPI) deficits in both juvenile and adult rats but these effects are not associated with maternal weight loss. Behav Brain Res 2010, 213:323-327.
    • (2010) Behav Brain Res , vol.213 , pp. 323-327
    • Wolff, A.R.1    Bilkey, D.K.2
  • 71
    • 0036222728 scopus 로고    scopus 로고
    • Visuospatial memory and learning in first-episode schizophreniform psychosis and established schizophrenia: a functional correlate of hippocampal pathology?
    • Wood S.J., Proffitt T., Mahony K., Smith D.J., Buchanan J.A., Brewer W., et al. Visuospatial memory and learning in first-episode schizophreniform psychosis and established schizophrenia: a functional correlate of hippocampal pathology?. Psychol Med 2002, 32:429-438.
    • (2002) Psychol Med , vol.32 , pp. 429-438
    • Wood, S.J.1    Proffitt, T.2    Mahony, K.3    Smith, D.J.4    Buchanan, J.A.5    Brewer, W.6
  • 72
    • 64249168387 scopus 로고    scopus 로고
    • Using the MATRICS to guide development of a preclinical cognitive test battery for research in schizophrenia
    • Young J.W., Powell S.B., Risbrough V., Marston H.M., Geyer M.A. Using the MATRICS to guide development of a preclinical cognitive test battery for research in schizophrenia. Pharmacol Ther 2009, 122:150-202.
    • (2009) Pharmacol Ther , vol.122 , pp. 150-202
    • Young, J.W.1    Powell, S.B.2    Risbrough, V.3    Marston, H.M.4    Geyer, M.A.5
  • 73
    • 84856113220 scopus 로고    scopus 로고
    • Prenatal exposure to a viral mimetic alters behavioural flexibility in male, but not female, rats
    • Zhang Y., Cazakoff B.N., Thai C.A., Howland J.G. Prenatal exposure to a viral mimetic alters behavioural flexibility in male, but not female, rats. Neuropharmacology 2012, 62:1299-1307.
    • (2012) Neuropharmacology , vol.62 , pp. 1299-1307
    • Zhang, Y.1    Cazakoff, B.N.2    Thai, C.A.3    Howland, J.G.4
  • 74
    • 64849086163 scopus 로고    scopus 로고
    • ELR-CXC chemokine receptor antagonism targets inflammatory responses at multiple levels
    • Zhao X., Town J.R., Li F., Zhang X., Cockcroft D.W., Gordon J.R. ELR-CXC chemokine receptor antagonism targets inflammatory responses at multiple levels. J Immunol 2009, 182:3213-3222.
    • (2009) J Immunol , vol.182 , pp. 3213-3222
    • Zhao, X.1    Town, J.R.2    Li, F.3    Zhang, X.4    Cockcroft, D.W.5    Gordon, J.R.6
  • 75
    • 77955985024 scopus 로고    scopus 로고
    • A novel ELR-CXC chemokine antagonist reduces intestinal ischemia reperfusion-induced mortality, and local and remote organ injury
    • Zhao X., Town J.R., Yang A., Zhang X., Paur N., Sawicki G., et al. A novel ELR-CXC chemokine antagonist reduces intestinal ischemia reperfusion-induced mortality, and local and remote organ injury. J Surg Res 2010, 162:264-273.
    • (2010) J Surg Res , vol.162 , pp. 264-273
    • Zhao, X.1    Town, J.R.2    Yang, A.3    Zhang, X.4    Paur, N.5    Sawicki, G.6
  • 76
    • 13844276635 scopus 로고    scopus 로고
    • Maternal immune activation leads to behavioral and pharmacological changes in the adult offspring
    • Zuckerman L., Weiner I. Maternal immune activation leads to behavioral and pharmacological changes in the adult offspring. J Psychiatr Res 2005, 39:311-323.
    • (2005) J Psychiatr Res , vol.39 , pp. 311-323
    • Zuckerman, L.1    Weiner, I.2


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