The combined CXCR1/CXCR2 antagonist CXCL8(3_74)K11R/G31P blocks neutrophil infiltration, pyrexia, and pulmonary vascular pathology in endotoxemic animals

Journal of Leukocyte Biology

Volumn 78, Issue 6, 2005, Pages 1265-1272

  Gordon, John R ^a,c   Li, Fang ^b   Zhang, Xiaobei ^a   Wang, Wenjun ^a   Zhao, Xixing ^a   Nayyar, Aarti ^a  

^a UNIVERSITY OF SASKATCHEWAN   (Canada)

^b DALIAN MEDICAL UNIVERSITY   (China)

^c Department of Veterinary Microbiology ^*  (Canada)

Author keywords

Chemokine; IL 8; Inflammation

Indexed keywords

CHEMOKINE; CHEMOKINE RECEPTOR CXCR1; CHEMOKINE RECEPTOR CXCR2; CYTOKINE; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; INTERLEUKIN 1; INTERLEUKIN 6; INTERLEUKIN 8; TUMOR NECROSIS FACTOR;

AIRWAY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOASSAY; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENDOTOXEMIA; ESCHERICHIA COLI; HISTOPATHOLOGY; INFLAMMATION; LUNG INFECTION; LUNG LAVAGE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; CHEMOKINES, CXC; CHEMOTAXIS, LEUKOCYTE; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTOXEMIA; FEMALE; FEVER; GUINEA PIGS; HEMORRHAGE; LIPOPOLYSACCHARIDES; LUNG; NEUTROPHIL INFILTRATION; NEUTROPHILS; PEPTIDE FRAGMENTS; PNEUMONIA; PULMONARY ARTERY; RECEPTORS, INTERLEUKIN-8A; RECEPTORS, INTERLEUKIN-8B; TIME FACTORS; TREATMENT OUTCOME;

ANIMALIA; CAVIA; ESCHERICHIA COLI;

EID: 28844452023     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.0805458     Document Type: Article

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