Cell crowding induces interferon regulatory factor 9, which confers resistance to chemotherapeutic drugs

International Journal of Cancer

Volumn 136, Issue 4, 2015, Pages E51-E61

  Kolosenko, Iryna ^a   Fryknäs, Mårten ^b   Forsberg, Sofi ^a   Johnsson, Per ^a   Cheon, Hyeonjoo ^c   Holvey Bates, Elise G ^c   Edsbäcker, Elin ^a   Pellegrini, Paola ^a   Rassoolzadeh, Hanif ^a   Brnjic, Slavica ^a   Larsson, Rolf ^b   Stark, George R ^c   Grander, Dan ^a   Linder, Stig ^a   Tamm, Katja Pokrovskaja ^a   De Milito, Angelo ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b UPPSALA UNIVERSITY HOSPITAL   (Sweden)

^c LERNER RESEARCH INSTITUTE   (United States)

Author keywords

Chemoresistance; Interferon stimulated genes; IRF9; Multicellular spheroids; STAT transcription factors

Indexed keywords

CISPLATIN; DOCETAXEL; ETOPOSIDE; FLUOROURACIL; INTERFERON; INTERFERON REGULATORY FACTOR 9; OXALIPLATIN; STAT1 PROTEIN; STAT2 PROTEIN; ANTINEOPLASTIC AGENT; IRF9 PROTEIN, HUMAN; STAT2 PROTEIN, HUMAN;

ARTICLE; CANCER CELL LINE; CANCER RESISTANCE; CELL CROWDING; CELL DENSITY; COLON CARCINOMA; CONTROLLED STUDY; DLD1 CELL LINE; DNA DAMAGE; GENE; GENE EXPRESSION; GENE FUNCTION; GENE INDUCTION; GENE SILENCING; HCT116 CELL LINE; HUMAN; HUMAN CELL; IFI27 GENE; IFITM1 GENE; IN VITRO STUDY; IRF9 GENE; MCF7 CELL LINE; MICROARRAY ANALYSIS; MOLECULAR CROWDING; MULTICELLULAR SPHEROID; OAS1 GENE; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; SKOV3 CELL LINE; STAT1 GENE; STAT2 GENE; UPREGULATION; APOPTOSIS; CELL COMMUNICATION; CELL SURVIVAL; DRUG EFFECTS; DRUG RESISTANCE; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PHYSIOLOGY; TRANSCRIPTION INITIATION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL COMMUNICATION; CELL SURVIVAL; DRUG RESISTANCE, NEOPLASM; GENE EXPRESSION REGULATION, NEOPLASTIC; HCT116 CELLS; HUMANS; INTERFERON-STIMULATED GENE FACTOR 3, GAMMA SUBUNIT; INTERFERONS; STAT2 TRANSCRIPTION FACTOR; TRANSCRIPTIONAL ACTIVATION;

EID: 84918515178     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.29161     Document Type: Article

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