-
1
-
-
0037204953
-
A road map for those who know JAK-STAT
-
Aaronson DS, Horvath CM. 2002. A road map for those who know JAK-STAT. Science 296:1653-1655
-
(2002)
Science
, vol.296
, pp. 1653-1655
-
-
Aaronson, D.S.1
Horvath, C.M.2
-
2
-
-
0026035169
-
Differential response of the human 6-16 and 9-27 genes to alpha and gamma interferons
-
Ackrill AM, Reid LE, Gilbert CS, Gewert DR, Porter AC, Lewin AR, Stark GR. 1991. Differential response of the human 6-16 and 9-27 genes to alpha and gamma interferons. Nucleic Acids Res 19:591-598
-
(1991)
Nucleic Acids Res
, vol.19
, pp. 591-598
-
-
Ackrill, A.M.1
Reid, L.E.2
Gilbert, C.S.3
Gewert, D.R.4
Porter, A.C.5
Lewin, A.R.6
Stark, G.R.7
-
4
-
-
36749069393
-
Interferons at age 50: Past, current and future impact on biomedicine
-
Borden EC, Sen GC, Uze G, Silverman RH, Ransohoff RM, Foster GR, Stark GR. 2007. Interferons at age 50: past, current and future impact on biomedicine. Nat Rev Drug Discov 6:975-990
-
(2007)
Nat Rev Drug Discov
, vol.6
, pp. 975-990
-
-
Borden, E.C.1
Sen, G.C.2
Uze, G.3
Silverman, R.H.4
Ransohoff, R.M.5
Foster, G.R.6
Stark, G.R.7
-
5
-
-
0028234529
-
Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
-
Darnell JE, Jr., Kerr IM, Stark GR. 1994. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 264:1415-1421
-
(1994)
Science
, vol.264
, pp. 1415-1421
-
-
Darnell Jr., J.E.1
Kerr, I.M.2
Stark, G.R.3
-
6
-
-
0032488662
-
Differential use of the betaL subunit of the type i interferon (IFN) receptor determines signaling specifi city for IFNalpha2 and IFNbeta
-
Domanski P, Nadeau OW, Platanias LC, Fish E, Kellum M, Pitha P, Colamonici OR. 1998. Differential use of the betaL subunit of the type I interferon (IFN) receptor determines signaling specifi city for IFNalpha2 and IFNbeta. J Biol Chem 273:3144-3147
-
(1998)
J Biol Chem
, vol.273
, pp. 3144-3147
-
-
Domanski, P.1
Nadeau, O.W.2
Platanias, L.C.3
Fish, E.4
Kellum, M.5
Pitha, P.6
Colamonici, O.R.7
-
7
-
-
16044369709
-
Immunodefi ciency and chronic myelogenous leukemialike syndrome in mice with a targeted mutation of the ICSBP gene
-
Holtschke T, Lohler J, Kanno Y, Fehr T, Giese N, Rosenbauer F, Lou J. 1996. Immunodefi ciency and chronic myelogenous leukemialike syndrome in mice with a targeted mutation of the ICSBP gene. Cell 87:307-317
-
(1996)
Cell
, vol.87
, pp. 307-317
-
-
Holtschke, T.1
Lohler, J.2
Kanno, Y.3
Fehr, T.4
Giese, N.5
Rosenbauer, F.6
Lou, J.7
-
8
-
-
0029678749
-
Essential and non-redundant roles of p48 (ISGF3 gamma) and IRF-1 in both type i and type II interferon responses, as revealed by gene targeting studies
-
Kimura T, Kadokawa Y, Harada H, Matsumoto M, Sato M, Kashiwazaki Y, Tarutani M. 1996. Essential and non-redundant roles of p48 (ISGF3 gamma) and IRF-1 in both type I and type II interferon responses, as revealed by gene targeting studies. Genes Cells 1:115-124
-
(1996)
Genes Cells
, vol.1
, pp. 115-124
-
-
Kimura, T.1
Kadokawa, Y.2
Harada, H.3
Matsumoto, M.4
Sato, M.5
Kashiwazaki, Y.6
Tarutani, M.7
-
9
-
-
0024295767
-
The leucine zipper: A hypothetical structure common to a new class of DNA binding proteins
-
Landschulz WH, Johnson PF, McKnight SL. 1988. The leucine zipper: a hypothetical structure common to a new class of DNA binding proteins. Science 240:1759-1764
-
(1988)
Science
, vol.240
, pp. 1759-1764
-
-
Landschulz, W.H.1
Johnson, P.F.2
McKnight, S.L.3
-
10
-
-
0028820423
-
Mutant U5A cells are complemented by an interferon-alpha beta receptor subunit generated by alternative processing of a new member of a cytokine receptor gene cluster
-
Lutfalla G, Holland SJ, Cinato E, Monneron D, Reboul J, Rogers NC, Smith JM. 1995. Mutant U5A cells are complemented by an interferon-alpha beta receptor subunit generated by alternative processing of a new member of a cytokine receptor gene cluster. EMBO J 14:5100-5108
-
(1995)
EMBO J
, vol.14
, pp. 5100-5108
-
-
Lutfalla, G.1
Holland, S.J.2
Cinato, E.3
Monneron, D.4
Reboul, J.5
Rogers, N.C.6
Smith, J.M.7
-
11
-
-
0027434082
-
Complementation of a mutant cell line: Central role of the 91 kDa polypeptide of ISGF3 in the interferon-alpha and -gamma signal transduction pathways
-
Muller M, Laxton C, Briscoe J, Schindler C, Improta T, Darnell JE, Jr., Stark GR. 1993. Complementation of a mutant cell line: central role of the 91 kDa polypeptide of ISGF3 in the interferon-alpha and -gamma signal transduction pathways. EMBO J 12:4221-4228
-
(1993)
EMBO J
, vol.12
, pp. 4221-4228
-
-
Muller, M.1
Laxton, C.2
Briscoe, J.3
Schindler, C.4
Improta, T.5
Darnell Jr., J.E.6
Stark, G.R.7
-
13
-
-
0030997409
-
Activation of Stat1 and subsequent transcription of inducible nitric oxide synthase gene in C6 glioma cells is independent of interferon-gamma- induced MAPK activation that is mediated by p21ras
-
Nishiya T, Uehara T, Edamatsu H, Kaziro Y, Itoh H, Nomura Y. 1997. Activation of Stat1 and subsequent transcription of inducible nitric oxide synthase gene in C6 glioma cells is independent of interferon-gamma-induced MAPK activation that is mediated by p21ras. FEBS Lett 408:33-38
-
(1997)
FEBS Lett
, vol.408
, pp. 33-38
-
-
Nishiya, T.1
Uehara, T.2
Edamatsu, H.3
Kaziro, Y.4
Itoh, H.5
Nomura, Y.6
-
14
-
-
0028299340
-
The human interferon alpha/beta receptor: Characterization and molecular cloning
-
Novick D, Cohen B, Rubinstein M. 1994. The human interferon alpha/beta receptor: characterization and molecular cloning. Cell 77:391-400
-
(1994)
Cell
, vol.77
, pp. 391-400
-
-
Novick, D.1
Cohen, B.2
Rubinstein, M.3
-
15
-
-
0036233585
-
Cytokine signaling in 2002: New surprises in the Jak/Stat pathway
-
O'Shea JJ, Gadina M, Schreiber RD. 2002. Cytokine signaling in 2002: new surprises in the Jak/Stat pathway. Cell 109(Suppl):S121-S131
-
(2002)
Cell
, vol.109
, Issue.SUPPL.
-
-
O'Shea, J.J.1
Gadina, M.2
Schreiber, R.D.3
-
16
-
-
0038441502
-
Phosphorylation of the Stat1 transactivating domain is required for the response to type i interferons
-
Pilz A, Ramsauer K, Heidari H, Leitges M, Kovarik P, Decker T. 2003. Phosphorylation of the Stat1 transactivating domain is required for the response to type I interferons. EMBO Rep 4:368-373
-
(2003)
EMBO Rep
, vol.4
, pp. 368-373
-
-
Pilz, A.1
Ramsauer, K.2
Heidari, H.3
Leitges, M.4
Kovarik, P.5
Decker, T.6
-
17
-
-
0032491401
-
The role of C/EBP isoforms in the control of infl ammatory and native immunity functions
-
Poli V. 1998. The role of C/EBP isoforms in the control of infl ammatory and native immunity functions J Biol Chem 273:29279-29282
-
(1998)
J Biol Chem
, vol.273
, pp. 29279-29282
-
-
Poli, V.1
-
19
-
-
0034677195
-
Regulation of c-myc expression by IFN-gamma through Stat1-dependent and -independent pathways
-
Ramana CV, Grammatikakis N, Chernov M, Nguyen H, Goh KC, Williams BR, Stark GR. 2000b. Regulation of c-myc expression by IFN-gamma through Stat1-dependent and -independent pathways. EMBO J 19:263-272
-
(2000)
EMBO J
, vol.19
, pp. 263-272
-
-
Ramana, C.V.1
Grammatikakis, N.2
Chernov, M.3
Nguyen, H.4
Goh, K.C.5
Williams, B.R.6
Stark, G.R.7
-
20
-
-
0035976928
-
A role for NF-kappa B in the induction of beta-R1 by interferon-beta
-
Rani MR, Asthagiri AR, Singh A, Sizemore N, Sathe SS, Li X, DiDonato JD. 2001. A role for NF-kappa B in the induction of beta-R1 by interferon-beta. J Biol Chem 276:44365-44368
-
(2001)
J Biol Chem
, vol.276
, pp. 44365-44368
-
-
Rani, M.R.1
Asthagiri, A.R.2
Singh, A.3
Sizemore, N.4
Sathe, S.S.5
Li, X.6
Didonato, J.D.7
-
21
-
-
0010136245
-
Characterization of beta-R1, a gene that is selectively induced by interferon beta (IFN-beta) compared with IFN-alpha
-
Rani MR, Foster GR, Leung S, Leaman D, Stark GR, Ransohoff RM. 1996. Characterization of beta-R1, a gene that is selectively induced by interferon beta (IFN-beta) compared with IFN-alpha. J Biol Chem 271:22878-22884
-
(1996)
J Biol Chem
, vol.271
, pp. 22878-22884
-
-
Rani, M.R.1
Foster, G.R.2
Leung, S.3
Leaman, D.4
Stark, G.R.5
Ransohoff, R.M.6
-
22
-
-
0037064119
-
Requirement of phosphoinositide 3-kinase and Akt for interferon- beta-mediated induction of the beta-R1 (SCYB11) gene
-
Rani MR, Hibbert L, Sizemore N, Stark GR, Ransohoff RM. 2002. Requirement of phosphoinositide 3-kinase and Akt for interferon- beta-mediated induction of the beta-R1 (SCYB11) gene. J Biol Chem 277:38456-38461
-
(2002)
J Biol Chem
, vol.277
, pp. 38456-38461
-
-
Rani, M.R.1
Hibbert, L.2
Sizemore, N.3
Stark, G.R.4
Ransohoff, R.M.5
-
23
-
-
34748862622
-
Requirement of catalytically active Tyk2 and accessory signals for the induction of TRAIL mRNA by IFN-beta
-
Rani MR, Pandalai S, Shrock J, Almasan A, Ransohoff RM. 2007. Requirement of catalytically active Tyk2 and accessory signals for the induction of TRAIL mRNA by IFN-beta. J Interferon Cytokine Res 27:767-779
-
(2007)
J Interferon Cytokine Res
, vol.27
, pp. 767-779
-
-
Rani, M.R.1
Pandalai, S.2
Shrock, J.3
Almasan, A.4
Ransohoff, R.M.5
-
24
-
-
30344483167
-
Alternative and accessory pathways in the regulation of IFN-beta-mediated gene expression
-
Rani MR, Ransohoff RM. 2005. Alternative and accessory pathways in the regulation of IFN-beta-mediated gene expression. J Interferon Cytokine Res 25:788-798
-
(2005)
J Interferon Cytokine Res
, vol.25
, pp. 788-798
-
-
Rani, M.R.1
Ransohoff, R.M.2
-
25
-
-
0037062498
-
MEKK1 plays a critical role in activating the transcription factor C/EBP-beta-dependent gene expression in response to IFN-gamma
-
Roy SK, Hu J, Meng Q, Xia Y, Shapiro PS, Reddy SP, Platanias LC. 2002. MEKK1 plays a critical role in activating the transcription factor C/EBP-beta-dependent gene expression in response to IFN-gamma. Proc Natl Acad Sci USA 99:7945-7950
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 7945-7950
-
-
Roy, S.K.1
Hu, J.2
Meng, Q.3
Xia, Y.4
Shapiro, P.S.5
Reddy, S.P.6
Platanias, L.C.7
-
26
-
-
21644474973
-
A role for mixed lineage kinases in regulating transcription factor CCAAT/enhancer-binding protein-{ beta}-dependent gene expression in response to interferon- {gamma}
-
Roy SK, Shuman JD, Platanias LC, Shapiro PS, Reddy SP, Johnson PF, Kalvakolanu DV. 2005. A role for mixed lineage kinases in regulating transcription factor CCAAT/enhancer-binding protein-{ beta}-dependent gene expression in response to interferon- {gamma}. J Biol Chem 280:24462-24471
-
(2005)
J Biol Chem
, vol.280
, pp. 24462-24471
-
-
Roy, S.K.1
Shuman, J.D.2
Platanias, L.C.3
Shapiro, P.S.4
Reddy, S.P.5
Johnson, P.F.6
Kalvakolanu, D.V.7
-
27
-
-
0034604551
-
Role of the intracellular domain of the human type i interferon receptor 2 chain (IFNAR2c) in interferon signaling. Expression of IFNAR2c truncation mutants in U5A cells
-
Russell-Harde D, Wagner TC, Rani MR, Vogel D, Colamonici O, Ransohoff RM, Majchrzak B. 2000. Role of the intracellular domain of the human type I interferon receptor 2 chain (IFNAR2c) in interferon signaling. Expression of IFNAR2c truncation mutants in U5A cells. J Biol Chem 275:23981-23985
-
(2000)
J Biol Chem
, vol.275
, pp. 23981-23985
-
-
Russell-Harde, D.1
Wagner, T.C.2
Rani, M.R.3
Vogel, D.4
Colamonici, O.5
Ransohoff, R.M.6
Majchrzak, B.7
-
28
-
-
0032579278
-
Interferon gamma activation of Raf-1 is Jak1-dependent and p21ras-independent
-
Sakatsume M, Stancato LF, David M, Silvennoinen O, Saharinen P, Pierce J, Larner AC. 1998. Interferon gamma activation of Raf-1 is Jak1-dependent and p21ras-independent. J Biol Chem 273:3021-3026
-
(1998)
J Biol Chem
, vol.273
, pp. 3021-3026
-
-
Sakatsume, M.1
Stancato, L.F.2
David, M.3
Silvennoinen, O.4
Saharinen, P.5
Pierce, J.6
Larner, A.C.7
-
29
-
-
0031657551
-
How cells respond to interferons
-
Stark GR, Kerr IM, Williams BR, Silverman RH, Schreiber RD. 1998. How cells respond to interferons. Annu Rev Biochem 67:227-264
-
(1998)
Annu Rev Biochem
, vol.67
, pp. 227-264
-
-
Stark, G.R.1
Kerr, I.M.2
Williams, B.R.3
Silverman, R.H.4
Schreiber, R.D.5
-
31
-
-
0028894979
-
Regulation of the interferon system and cell growth by the IRF transcription factors
-
Taniguchi T, Harada H, Lamphier M. 1995. Regulation of the interferon system and cell growth by the IRF transcription factors. J Cancer Res Clin Oncol 121:516-520
-
(1995)
J Cancer Res Clin Oncol
, vol.121
, pp. 516-520
-
-
Taniguchi, T.1
Harada, H.2
Lamphier, M.3
-
32
-
-
0025015138
-
Genetic transfer of a functional human interferon alpha receptor into mouse cells: Cloning and expression of its cDNA
-
Uze G, Lutfalla G, Gresser I. 1990. Genetic transfer of a functional human interferon alpha receptor into mouse cells: cloning and expression of its cDNA. Cell 60:225-234
-
(1990)
Cell
, vol.60
, pp. 225-234
-
-
Uze, G.1
Lutfalla, G.2
Gresser, I.3
-
33
-
-
0037059781
-
Interferon signaling is dependent on specifi c tyrosines located within the intracellular domain of IFNAR2c. Expression of IFNAR2c tyrosine mutants in U5A cells
-
Wagner TC, Velichko S, Vogel D, Rani MR, Leung S, Ransohoff RM, Stark GR. 2002. Interferon signaling is dependent on specifi c tyrosines located within the intracellular domain of IFNAR2c. Expression of IFNAR2c tyrosine mutants in U5A cells. J Biol Chem 277:1493-1499
-
(2002)
J Biol Chem
, vol.277
, pp. 1493-1499
-
-
Wagner, T.C.1
Velichko, S.2
Vogel, D.3
Rani, M.R.4
Leung, S.5
Ransohoff, R.M.6
Stark, G.R.7
-
34
-
-
0141497028
-
Dysregulated Sonic hedgehog signaling and medulloblastoma consequent to IFN-alpha-stimulated STAT2-independent production of IFN-gamma in the brain
-
Wang J, Pham-Mitchell N, Schindler C, Campbell IL. 2003. Dysregulated Sonic hedgehog signaling and medulloblastoma consequent to IFN-alpha-stimulated STAT2-independent production of IFN-gamma in the brain. J Clin Invest 112:535-543
-
(2003)
J Clin Invest
, vol.112
, pp. 535-543
-
-
Wang, J.1
Pham-Mitchell, N.2
Schindler, C.3
Campbell, I.L.4
-
35
-
-
0031031694
-
Interferon gammainduced transcription of the murine ISGF3gamma (p48) gene is mediated by novel factors
-
Weihua X, Kolla V, Kalvakolanu DV. 1997a. Interferon gammainduced transcription of the murine ISGF3gamma (p48) gene is mediated by novel factors. Proc Natl Acad Sci USA 94:103-108
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 103-108
-
-
Weihua, X.1
Kolla, V.2
Kalvakolanu, D.V.3
-
36
-
-
0030785597
-
The interferoninducible murine p48 (ISGF3gamma) gene is regulated by protooncogene c-myc
-
Weihua X, Lindner DJ, Kalvakolanu DV. 1997b. The interferoninducible murine p48 (ISGF3gamma) gene is regulated by protooncogene c-myc. Proc Natl Acad Sci USA 94:7227-7232
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 7227-7232
-
-
Weihua, X.1
Lindner, D.J.2
Kalvakolanu, D.V.3
-
37
-
-
0035968309
-
CCAAT/enhancer-binding protein beta mediates interferon- gamma-induced p48 (ISGF3-gamma) gene transcription in human monocytic cells
-
Xiao W, Wang L, Yang X, Chen T, Hodge D, Johnson PF, Farrar W. 2001. CCAAT/enhancer-binding protein beta mediates interferon- gamma-induced p48 (ISGF3-gamma) gene transcription in human monocytic cells. J Biol Chem 276:23275-23281
-
(2001)
J Biol Chem
, vol.276
, pp. 23275-23281
-
-
Xiao, W.1
Wang, L.2
Yang, X.3
Chen, T.4
Hodge, D.5
Johnson, P.F.6
Farrar, W.7
-
38
-
-
0029670220
-
Phosphorylated interferon-alpha receptor 1 subunit (IFNaR1) acts as a docking site for the latent form of the 113 kDa STAT2 protein
-
Yan H, Krishnan K, Greenlund AC, Gupta S, Lim JT, Schreiber RD, Schindler CW. 1996. Phosphorylated interferon-alpha receptor 1 subunit (IFNaR1) acts as a docking site for the latent form of the 113 kDa STAT2 protein. EMBO J 15:1064-1074
-
(1996)
EMBO J
, vol.15
, pp. 1064-1074
-
-
Yan, H.1
Krishnan, K.2
Greenlund, A.C.3
Gupta, S.4
Lim, J.T.5
Schreiber, R.D.6
Schindler, C.W.7
|