Reduced expression of TLR3, TLR10 and TREM1 by human macrophages in Chronic cavitary pulmonary aspergillosis, and novel associations of VEGFA, DENND1B and PLAT

Clinical Microbiology and Infection

Volumn 20, Issue 11, 2014, Pages O960-O968

  Smith, N L D ^a,b,c,d,e   Hankinson, J ^b,c,d,e   Simpson, A ^b,c,d,e   Denning, D W ^a,b,c,d,e   Bowyer, P ^a,b,c,d,e  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

^d MANCHESTER UNIVERSITY NHS FOUNDATION TRUST   (United Kingdom)

^e NIHR South Manchester Respiratory and Allergy Clinical Research Facility   (United Kingdom)

Author keywords

Aspergillus fumigatus; CCPA; TLR; Aspergilloma; Aspergillosis; Gene expression; Genetic susceptibility; Immune response; Monocyte derived macrophages

Indexed keywords

DECTIN 1; DENN/MADD DOMAIN CONTAINING 1B; MEMBRANE PROTEIN; PLASMINOGEN ACTIVATOR; TOLL LIKE RECEPTOR 10; TOLL LIKE RECEPTOR 3; TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 1; UNCLASSIFIED DRUG; VASCULOTROPIN A; DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEIN; DENND1B PROTEIN, HUMAN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; IMMUNOGLOBULIN RECEPTOR; PLAT PROTEIN, HUMAN; TISSUE PLASMINOGEN ACTIVATOR; TLR10 PROTEIN, HUMAN; TLR3 PROTEIN, HUMAN; TREM1 PROTEIN, HUMAN; VEGFA PROTEIN, HUMAN;

ADULT; AGED; ANGIOGENESIS; ARTICLE; ASPERGILLUS FUMIGATUS; CHRONIC CAVITARY PULMONARY ASPERGILLOSIS; COCULTURE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; HUMAN; LUNG ASPERGILLOSIS; MACROPHAGE; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; PLASMINOGEN ACTIVATION; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; BIOSYNTHESIS; GENETIC PREDISPOSITION; GENETICS; IMMUNOLOGY; ISOLATION AND PURIFICATION;

ASPERGILLUS FUMIGATUS; FUNGI;

ADULT; AGED; ASPERGILLUS FUMIGATUS; DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEINS; FEMALE; GENE EXPRESSION; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; MACROPHAGES; MALE; MEMBRANE GLYCOPROTEINS; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; PULMONARY ASPERGILLOSIS; RECEPTORS, IMMUNOLOGIC; TISSUE PLASMINOGEN ACTIVATOR; TOLL-LIKE RECEPTOR 10; TOLL-LIKE RECEPTOR 3; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84917735844     PISSN: 1198743X     EISSN: 14690691     Source Type: Journal    
DOI: 10.1111/1469-0691.12643     Document Type: Article

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