A prominent role for the IL1 pathway and IL15 in susceptibility to chronic cavitary pulmonary aspergillosis

Clinical Microbiology and Infection

Volumn 20, Issue 8, 2014, Pages

  Smith, N L D ^a,b,c,d,e   Hankinson, J ^b,c,d,e   Simpson, A ^b,c,d,e   Bowyer, P ^a,b,c,d,e   Denning, D W ^a,b,c,d,e  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

^d MANCHESTER UNIVERSITY NHS FOUNDATION TRUST   (United Kingdom)

^e NIHR South Manchester Respiratory and Allergy Clinical Research Facility   (United Kingdom)

Author keywords

Aspergillosis; Aspergillus fumigatus; CCPA; Genetic susceptibility; IL1; IL15; Immune response; Monocyte derived macrophages

Indexed keywords

INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 2; INTERLEUKIN 15; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 6; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; IL15 PROTEIN, HUMAN; IL1B PROTEIN, HUMAN; IL1RN PROTEIN, HUMAN; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT;

ADULT; AGED; ARTICLE; ASPERGILLUS FUMIGATUS; CHRONIC CAVITARY PULMONARY ASPERGILLOSIS; CONTROLLED STUDY; DISEASE COURSE; DISEASE PREDISPOSITION; FEMALE; GENE; GENE EXPRESSION; GENETIC ASSOCIATION; GENOTYPE; HUMAN; IMMUNE RESPONSE; INFLAMMATION; LUNG ASPERGILLOSIS; MACROPHAGE; MAJOR CLINICAL STUDY; MALE; MONOCYTE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; GENETIC PREDISPOSITION; GENETICS; IMMUNOLOGY; MIDDLE AGED;

ASPERGILLUS FUMIGATUS;

ADULT; AGED; ASPERGILLUS FUMIGATUS; FEMALE; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; INTERLEUKIN-15; INTERLEUKIN-1BETA; MACROPHAGES; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; PULMONARY ASPERGILLOSIS;

EID: 84906789726     PISSN: 1198743X     EISSN: 14690691     Source Type: Journal    
DOI: 10.1111/1469-0691.12473     Document Type: Article

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