-
2
-
-
0041435762
-
-
Atlanta Georgia: American Cancer Society
-
ACS. Cancer facts and figures. Atlanta Georgia: American Cancer Society; 2012.
-
(2012)
Cancer Facts and Figures.
-
-
-
3
-
-
80051809050
-
Documenting the natural history of patients with resected stage II adenocarcinoma of the colon after random assignment to adjuvant treatment with edrecolomab or observation: Results from CALGB 9581
-
Niedzwiecki D, Bertagnolli MM, Warren RS, Compton CC, Kemeny NE, Benson AB III, et al. Documenting the natural history of patients with resected stage II adenocarcinoma of the colon after random assignment to adjuvant treatment with edrecolomab or observation: results from CALGB 9581. J Clin Oncol 2011; 29:3146-52.
-
(2011)
J Clin Oncol
, vol.29
, pp. 3146-3152
-
-
Niedzwiecki, D.1
Bertagnolli, M.M.2
Warren, R.S.3
Compton, C.C.4
Kemeny, N.E.5
Benson, A.B.6
-
4
-
-
73349116176
-
Barriers to integrating gene profiling for stage II colon cancer
-
Kopetz S, Abbruzzese JL. Barriers to integrating gene profiling for stage II colon cancer. Clin Cancer Res 2009;15:7451-2.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 7451-7452
-
-
Kopetz, S.1
Abbruzzese, J.L.2
-
5
-
-
84864190709
-
A network-based gene expression signature informs prognosis and treatment for colorectal cancer patients
-
Shi M, Beauchamp RD, Zhang B. A network-based gene expression signature informs prognosis and treatment for colorectal cancer patients. PLoS ONE 2012;7:e41292.
-
(2012)
PLoS ONE
, vol.7
, pp. e41292
-
-
Shi, M.1
Beauchamp, R.D.2
Zhang, B.3
-
6
-
-
0036234543
-
NFAT signaling: Choreographing the social lives of cells
-
Crabtree GR, Olson EN. NFAT signaling: choreographing the social lives of cells. Cell 2002;109::S67-79.
-
(2002)
Cell
, vol.109
, pp. S67-S79
-
-
Crabtree, G.R.1
Olson, E.N.2
-
7
-
-
0141483523
-
Transcriptional regulation by calcium, calcineurin, and NFAT
-
Hogan PG, Chen L, Nardone J, Rao A. Transcriptional regulation by calcium, calcineurin, and NFAT. Genes Dev 2003;17:2205-32.
-
(2003)
Genes Dev
, vol.17
, pp. 2205-2232
-
-
Hogan, P.G.1
Chen, L.2
Nardone, J.3
Rao, A.4
-
8
-
-
20644466433
-
NFAT proteins: Key regulators of T-cell development and function
-
Macian F. NFAT proteins: key regulators of T-cell development and function. Nat Rev Immunol 2005;5:472-84.
-
(2005)
Nat Rev Immunol
, vol.5
, pp. 472-484
-
-
Macian, F.1
-
10
-
-
0032212631
-
Inhibitory function of two NFAT family members in lymphoid homeostasis and Th2 development
-
Ranger AM, Oukka M, Rengarajan J, Glimcher LH. Inhibitory function of two NFAT family members in lymphoid homeostasis and Th2 development. Immunity 1998;9:627-35.
-
(1998)
Immunity
, vol.9
, pp. 627-635
-
-
Ranger, A.M.1
Oukka, M.2
Rengarajan, J.3
Glimcher, L.H.4
-
11
-
-
84882574582
-
Acquired expression of NFATc1 downregulates E-cadherin and promotes cancer cell invasion
-
Oikawa T, Nakamura A, Onishi N, Yamada T, Matsuo K, Saya H. Acquired expression of NFATc1 downregulates E-cadherin and promotes cancer cell invasion. Cancer Res 2013;73:5100-9.
-
(2013)
Cancer Res
, vol.73
, pp. 5100-5109
-
-
Oikawa, T.1
Nakamura, A.2
Onishi, N.3
Yamada, T.4
Matsuo, K.5
Saya, H.6
-
12
-
-
38649106497
-
NFATc1 balances quiescence and proliferation of skin stem cells
-
Horsley V, Aliprantis AO, Polak L, Glimcher LH, Fuchs E. NFATc1 balances quiescence and proliferation of skin stem cells. Cell 2008; 132:299-310.
-
(2008)
Cell
, vol.132
, pp. 299-310
-
-
Horsley, V.1
Aliprantis, A.O.2
Polak, L.3
Glimcher, L.H.4
Fuchs, E.5
-
13
-
-
77951028117
-
NFAT3 transcription factor inhibits breast cancer cell motility by targeting the Lipocalin 2 gene
-
FougereM, Gaudineau B, Barbier J, Guaddachi F, Feugeas JP, Auboeuf D, et al. NFAT3 transcription factor inhibits breast cancer cell motility by targeting the Lipocalin 2 gene. Oncogene 2010;29:2292-301.
-
(2010)
Oncogene
, vol.29
, pp. 2292-2301
-
-
Fougere, M.1
Gaudineau, B.2
Barbier, J.3
Guaddachi, F.4
Feugeas, J.P.5
Auboeuf, D.6
-
14
-
-
77956258205
-
Sequential activation of NFAT and c-Myc transcription factors mediates the TGF-beta switch from a suppressor to a promoter of cancer cell proliferation
-
Singh G, Singh SK, Konig A, Reutlinger K, Nye MD, Adhikary T, et al. Sequential activation of NFAT and c-Myc transcription factors mediates the TGF-beta switch from a suppressor to a promoter of cancer cell proliferation. J Biol Chem 2010;285:27241-50.
-
(2010)
J Biol Chem
, vol.285
, pp. 27241-27250
-
-
Singh, G.1
Singh, S.K.2
Konig, A.3
Reutlinger, K.4
Nye, M.D.5
Adhikary, T.6
-
15
-
-
77249143960
-
Experimentally derived metastasis gene expression profile predicts recurrence and death in patients with colon cancer
-
Smith JJ, Deane NG, Wu F, Merchant NB, Zhang B, Jiang A, et al. Experimentally derived metastasis gene expression profile predicts recurrence and death in patients with colon cancer. Gastroenterology 2010;138:958-68.
-
(2010)
Gastroenterology
, vol.138
, pp. 958-968
-
-
Smith, J.J.1
Deane, N.G.2
Wu, F.3
Merchant, N.B.4
Zhang, B.5
Jiang, A.6
-
16
-
-
77952687416
-
Co-expression module analysis reveals biological processes, genomic gain, and regulatory mechanisms associated with breast cancer progression
-
Shi Z, Derow CK, Zhang B. Co-expression module analysis reveals biological processes, genomic gain, and regulatory mechanisms associated with breast cancer progression. BMC Syst Biol 2010;4:74.
-
(2010)
BMC Syst Biol
, vol.4
, pp. 74
-
-
Shi, Z.1
Derow, C.K.2
Zhang, B.3
-
17
-
-
23144464901
-
WebGestalt: An integrated system for exploring gene sets in various biological contexts
-
Zhang B, Kirov S, Snoddy J. WebGestalt: an integrated system for exploring gene sets in various biological contexts. Nucleic Acids Res 2005;33:W741-8.
-
(2005)
Nucleic Acids Res
, vol.33
, pp. W741-W748
-
-
Zhang, B.1
Kirov, S.2
Snoddy, J.3
-
18
-
-
33845432928
-
Adjusting batch effects in microarray expression data using empirical Bayes methods
-
Johnson WE, Li C, Rabinovic A. Adjusting batch effects in microarray expression data using empirical Bayes methods. Biostatistics 2007;8:118-27.
-
(2007)
Biostatistics
, vol.8
, pp. 118-127
-
-
Johnson, W.E.1
Li, C.2
Rabinovic, A.3
-
19
-
-
84863125635
-
Smad4-mediated signaling inhibits intestinal neoplasia by inhibiting expression of beta-catenin
-
Freeman TJ, Smith JJ, Chen X, Washington MK, Roland JT, Means AL, et al. Smad4-mediated signaling inhibits intestinal neoplasia by inhibiting expression of beta-catenin. Gastroenterology 2012;142:562-71 e562.
-
(2012)
Gastroenterology
, vol.142
, pp. 562-71e562
-
-
Freeman, T.J.1
Smith, J.J.2
Chen, X.3
Washington, M.K.4
Roland, J.T.5
Means, A.L.6
-
20
-
-
0036773634
-
NFAT1 and NFAT2 are positive regulators of IL-4 gene transcription
-
Monticelli S, Rao A. NFAT1 and NFAT2 are positive regulators of IL-4 gene transcription. Eur J Immunol 2002;32:2971-8.
-
(2002)
Eur J Immunol
, vol.32
, pp. 2971-2978
-
-
Monticelli, S.1
Rao, A.2
-
21
-
-
42149116826
-
A map of human protein interactions derived from co-expression of human mRNAs and their orthologs
-
Ramani AK, Li Z, Hart GT, CarlsonMW, Boutz DR, Marcotte EM. A map of human protein interactions derived from co-expression of human mRNAs and their orthologs. Mol Syst Biol 2008;4:180.
-
(2008)
Mol Syst Biol
, vol.4
, pp. 180
-
-
Ramani, A.K.1
Li, Z.2
Hart, G.T.3
Carlson, M.W.4
Boutz, D.R.5
Marcotte, E.M.6
-
22
-
-
0742305866
-
Network biology: Understanding the cell's functional organization
-
Barabasi AL, Oltvai ZN. Network biology: understanding the cell's functional organization. Nat Rev Genet 2004;5:101-13.
-
(2004)
Nat Rev Genet
, vol.5
, pp. 101-113
-
-
Barabasi, A.L.1
Oltvai, Z.N.2
-
23
-
-
67650999875
-
The basics of epithelial-mesenchymal transition
-
Kalluri R, Weinberg RA. The basics of epithelial-mesenchymal transition. J Clin Invest 2009;119:1420-8.
-
(2009)
J Clin Invest
, vol.119
, pp. 1420-1428
-
-
Kalluri, R.1
Weinberg, R.A.2
-
24
-
-
84896691027
-
Deciphering genomic alterations in colorectal cancer through transcriptional subtype-based network analysis
-
Zhu J, Wang J, Shi Z, Franklin JL, Deane NG, Coffey RJ, et al. Deciphering genomic alterations in colorectal cancer through transcriptional subtype-based network analysis. PLoS ONE 2013;8: e79282.
-
(2013)
PLoS ONE
, vol.8
, pp. e79282
-
-
Zhu, J.1
Wang, J.2
Shi, Z.3
Franklin, J.L.4
Deane, N.G.5
Coffey, R.J.6
-
25
-
-
84855175895
-
Human cancer cells express Slug-based epithelialmesenchymal transition gene expression signature obtained in vivo
-
Anastassiou D, Rumjantseva V, Cheng W, Huang J, Canoll PD, Yamashiro DJ, et al. Human cancer cells express Slug-based epithelialmesenchymal transition gene expression signature obtained in vivo. BMC Cancer 2011;11:529.
-
(2011)
BMC Cancer
, vol.11
, pp. 529
-
-
Anastassiou, D.1
Rumjantseva, V.2
Cheng, W.3
Huang, J.4
Canoll, P.D.5
Yamashiro, D.J.6
-
26
-
-
78651529782
-
EMT is the dominant program in human colon cancer
-
Loboda A, Nebozhyn MV, Watters JW, Buser CA, Shaw PM, Huang PS, et al. EMT is the dominant program in human colon cancer. BMC Med Genomics 2011;4:9.
-
(2011)
BMC Med Genomics
, vol.4
, pp. 9
-
-
Loboda, A.1
Nebozhyn, M.V.2
Watters, J.W.3
Buser, C.A.4
Shaw, P.M.5
Huang, P.S.6
-
27
-
-
84865012891
-
Prognostic gene expression signature associated with two molecularly distinct subtypes of colorectal cancer
-
Oh SC, Park YY, Park ES, Lim JY, Kim SM, Kim SB, et al. Prognostic gene expression signature associated with two molecularly distinct subtypes of colorectal cancer. Gut 2012;61:1291-8.
-
(2012)
Gut
, vol.61
, pp. 1291-1298
-
-
Oh, S.C.1
Park, Y.Y.2
Park, E.S.3
Lim, J.Y.4
Kim, S.M.5
Kim, S.B.6
-
28
-
-
33846455463
-
Gene expression profiling reveals a massive, aneuploidy-dependent transcriptional deregulation and distinct differences between lymph node-negative and lymph node-positive colon carcinomas
-
Grade M, Hormann P, Becker S, Hummon AB, Wangsa D, Varma S, et al. Gene expression profiling reveals a massive, aneuploidy-dependent transcriptional deregulation and distinct differences between lymph node-negative and lymph node-positive colon carcinomas. Cancer Res 2007;67:41-56.
-
(2007)
Cancer Res
, vol.67
, pp. 41-56
-
-
Grade, M.1
Hormann, P.2
Becker, S.3
Hummon, A.B.4
Wangsa, D.5
Varma, S.6
-
29
-
-
41149157649
-
TGFbeta primes breast tumors for lung metastasis seeding through angiopoietin-like 4
-
Padua D, Zhang XH, Wang Q, Nadal C, Gerald WL, Gomis RR, et al. TGFbeta primes breast tumors for lung metastasis seeding through angiopoietin-like 4. Cell 2008;133:66-77.
-
(2008)
Cell
, vol.133
, pp. 66-77
-
-
Padua, D.1
Zhang, X.H.2
Wang, Q.3
Nadal, C.4
Gerald, W.L.5
Gomis, R.R.6
-
30
-
-
84856233403
-
Restricted heterochromatin formation links NFATc2 repressor activity with growth promotion in pancreatic cancer
-
e381-7
-
Baumgart S, Glesel E, Singh G, Chen NM, Reutlinger K, Zhang J, et al. Restricted heterochromatin formation links NFATc2 repressor activity with growth promotion in pancreatic cancer. Gastroenterology 2012; 142:388-98 e381-7.
-
(2012)
Gastroenterology
, vol.142
, pp. 388-398
-
-
Baumgart, S.1
Glesel, E.2
Singh, G.3
Chen, N.M.4
Reutlinger, K.5
Zhang, J.6
-
31
-
-
77249176619
-
NFAT-induced histone acetylation relay switch promotes c-Mycdependent growth in pancreatic cancer cells
-
e1181-2
-
Koenig A, Linhart T, Schlengemann K, Reutlinger K, Wegele J, Adler G, et al. NFAT-induced histone acetylation relay switch promotes c-Mycdependent growth in pancreatic cancer cells. Gastroenterology 2010;138:1189-99 e1181-2.
-
(2010)
Gastroenterology
, vol.138
, pp. 1189-1199
-
-
Koenig, A.1
Linhart, T.2
Schlengemann, K.3
Reutlinger, K.4
Wegele, J.5
Adler, G.6
-
32
-
-
33747616250
-
Overexpression of c-myc in pancreatic cancer caused by ectopic activation of NFATc1 and the Ca2+/calcineurin signaling pathway
-
Buchholz M, Schatz A, Wagner M, Michl P, Linhart T, Adler G, et al. Overexpression of c-myc in pancreatic cancer caused by ectopic activation of NFATc1 and the Ca2 +/calcineurin signaling pathway. EMBO J 2006;25:3714-24.
-
(2006)
EMBO J
, vol.25
, pp. 3714-3724
-
-
Buchholz, M.1
Schatz, A.2
Wagner, M.3
Michl, P.4
Linhart, T.5
Adler, G.6
-
33
-
-
27744591989
-
A tumor-suppressor function for NFATc3 in T-cell lymphomagenesis by murine leukemia virus
-
Glud SZ, Sorensen AB, Andrulis M,Wang B, Kondo E, Jessen R, et al.A tumor-suppressor function for NFATc3 in T-cell lymphomagenesis by murine leukemia virus. Blood 2005;106:3546-52.
-
(2005)
Blood
, vol.106
, pp. 3546-3552
-
-
Glud, S.Z.1
Sorensen, A.B.2
Andrulis, M.3
Wang, B.4
Kondo, E.5
Jessen, R.6
-
34
-
-
34250025396
-
Targeting calcineurin activation as a therapeutic strategy for T-cell acute lymphoblastic leukemia
-
Medyouf H, Alcalde H, Berthier C, Guillemin MC, dos Santos NR, Janin A, et al. Targeting calcineurin activation as a therapeutic strategy for T-cell acute lymphoblastic leukemia. Nat Med 2007; 13:736-41.
-
(2007)
Nat Med
, vol.13
, pp. 736-741
-
-
Medyouf, H.1
Alcalde, H.2
Berthier, C.3
Guillemin, M.C.4
Dos Santos, N.R.5
Janin, A.6
-
35
-
-
62549124971
-
Akt/protein kinase b and glycogen synthase kinase-3beta signaling pathway regulates cell migration through the NFAT1 transcription factor
-
Yoeli-Lerner M, Chin YR, Hansen CK, Toker A. Akt/protein kinase b and glycogen synthase kinase-3beta signaling pathway regulates cell migration through the NFAT1 transcription factor. Mol Cancer Res 2009;7:425-32.
-
(2009)
Mol Cancer Res
, vol.7
, pp. 425-432
-
-
Yoeli-Lerner, M.1
Chin, Y.R.2
Hansen, C.K.3
Toker, A.4
-
36
-
-
27944446105
-
Akt blocks breast cancer cell motility and invasion through the transcription factor NFAT
-
Yoeli-Lerner M, Yiu GK, Rabinovitz I, Erhardt P, Jauliac S, Toker A. Akt blocks breast cancer cell motility and invasion through the transcription factor NFAT. Mol Cell 2005;20:539-550.
-
(2005)
Mol Cell
, vol.20
, pp. 539-550
-
-
Yoeli-Lerner, M.1
Yiu, G.K.2
Rabinovitz, I.3
Erhardt, P.4
Jauliac, S.5
Toker, A.6
|