Sequence divergence and diversity suggests ongoing functional diversification of vertebrate NAD metabolism

DNA Repair

Volumn 23, Issue , 2014, Pages 39-48

  Gossmann, Toni I ^a   Ziegler, Mathias ^b  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b UNIVERSITY OF BERGEN   (Norway)

Author keywords

NAD metabolism; PARP; Pathway evolution; Positive selection

Indexed keywords

AMINO ACID; NICOTINAMIDE ADENINE DINUCLEOTIDE; ENZYME; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NUCLEAR PROTEIN; PARP14 PROTEIN, HUMAN; PARP4 PROTEIN, HUMAN;

APOPTOSIS; ARTICLE; CLADISTICS; DNA BINDING; DNA DAMAGE; DNA REPAIR; DNA SEQUENCE; ENZYME ACTIVE SITE; ENZYME DEGRADATION; ENZYME METABOLISM; EUKARYOTE; GENETIC VARIABILITY; HAPLOTYPE; HUMAN; INTRASPECIFIC VARIATION; MAMMAL; MOLECULAR EVOLUTION; NATURAL SELECTION; NONHUMAN; ORTHOLOGY; POINT MUTATION; POLYMERIZATION; PROTEIN FAMILY; PURIFYING SELECTION; SIGNAL TRANSDUCTION; SPECIES DIVERSITY; VERTEBRATE; AMINO ACID SEQUENCE; ANIMAL; ARABIDOPSIS; BIOLOGICAL MODEL; DROSOPHILA; GENETIC SELECTION; GENETICS; METABOLISM; MOLECULAR GENETICS; MOUSE; MUTATION RATE; POPULATION GENETICS;

EUKARYOTA; VERTEBRATA;

AMINO ACID SEQUENCE; ANIMALS; ARABIDOPSIS; CATALYTIC DOMAIN; DROSOPHILA; ENZYMES; EVOLUTION, MOLECULAR; GENETICS, POPULATION; HUMANS; MAMMALS; MICE; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; MUTATION RATE; NAD; NUCLEAR PROTEINS; POLY(ADP-RIBOSE) POLYMERASES; SELECTION, GENETIC; VERTEBRATES;

EID: 84917694641     PISSN: 15687864     EISSN: 15687856     Source Type: Journal    
DOI: 10.1016/j.dnarep.2014.07.005     Document Type: Article

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