메뉴 건너뛰기




Volumn 330, Issue 1, 2015, Pages 199-211

The MAPK ERK5, but not ERK1/2, inhibits the progression of monocytic phenotype to the functioning macrophage

Author keywords

AML; ERK1 2; ERK5; M CSFR; MAPK; Vitamin D

Indexed keywords

CALCITRIOL; COLONY STIMULATING FACTOR 1; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE 7; COLONY STIMULATING FACTOR RECEPTOR; MAPK1 PROTEIN, HUMAN; PROTEIN KINASE INHIBITOR;

EID: 84916937190     PISSN: 00144827     EISSN: 10902422     Source Type: Journal    
DOI: 10.1016/j.yexcr.2014.10.003     Document Type: Article
Times cited : (20)

References (63)
  • 3
    • 0842346188 scopus 로고    scopus 로고
    • Regulation of myeloid development and function by colony stimulating factors
    • Barreda D.R., Hanington P.C., Belosevic M. Regulation of myeloid development and function by colony stimulating factors. Dev. Comp. Immunol. 2004, 28:509-554.
    • (2004) Dev. Comp. Immunol. , vol.28 , pp. 509-554
    • Barreda, D.R.1    Hanington, P.C.2    Belosevic, M.3
  • 4
    • 84873103649 scopus 로고    scopus 로고
    • Colony stimulating factors and myeloid cell biology in health and disease
    • Hamilton J.A., Achuthan A. Colony stimulating factors and myeloid cell biology in health and disease. Trends Immunol. 2013, 34:81-89.
    • (2013) Trends Immunol. , vol.34 , pp. 81-89
    • Hamilton, J.A.1    Achuthan, A.2
  • 6
    • 84859247055 scopus 로고    scopus 로고
    • CSF-1 signaling in macrophages: pleiotrophy through phosphotyrosine-based signaling pathways
    • Mouchemore K.A., Pixley F.J. CSF-1 signaling in macrophages: pleiotrophy through phosphotyrosine-based signaling pathways. Crit. Rev. Clin. Lab. Sci. 2012, 49:49-61.
    • (2012) Crit. Rev. Clin. Lab. Sci. , vol.49 , pp. 49-61
    • Mouchemore, K.A.1    Pixley, F.J.2
  • 8
    • 70350345564 scopus 로고    scopus 로고
    • Granulocyte colony-stimulating factor receptor: stimulating granulopoiesis and much more
    • Liongue C., Wright C., Russell A.P., Ward A.C. Granulocyte colony-stimulating factor receptor: stimulating granulopoiesis and much more. Int. J. Biochem. Cell Biol. 2009, 41:2372-2375.
    • (2009) Int. J. Biochem. Cell Biol. , vol.41 , pp. 2372-2375
    • Liongue, C.1    Wright, C.2    Russell, A.P.3    Ward, A.C.4
  • 10
    • 0033973482 scopus 로고    scopus 로고
    • Early events in M-CSF receptor signaling
    • Bourette R.P., Rohrschneider L.R. Early events in M-CSF receptor signaling. Growth Factors 2000, 17:155-166.
    • (2000) Growth Factors , vol.17 , pp. 155-166
    • Bourette, R.P.1    Rohrschneider, L.R.2
  • 11
    • 34347393493 scopus 로고    scopus 로고
    • M-CSF-mediated macrophage differentiation but not proliferation is correlated with increased and prolonged ERK activation
    • Suzu S., Hiyoshi M., Yoshidomi Y., Harada H., Takeya M., Kimura F., Motoyoshi K., Okada S. M-CSF-mediated macrophage differentiation but not proliferation is correlated with increased and prolonged ERK activation. J. Cell Physiol. 2007, 212:519-525.
    • (2007) J. Cell Physiol. , vol.212 , pp. 519-525
    • Suzu, S.1    Hiyoshi, M.2    Yoshidomi, Y.3    Harada, H.4    Takeya, M.5    Kimura, F.6    Motoyoshi, K.7    Okada, S.8
  • 13
    • 0035044042 scopus 로고    scopus 로고
    • Scaffolding protein Gab2 mediates differentiation signaling downstream of Fms receptor tyrosine kinase
    • Liu Y., Jenkins B., Shin J.L., Rohrschneider L.R. Scaffolding protein Gab2 mediates differentiation signaling downstream of Fms receptor tyrosine kinase. Mol. Cell Biol. 2001, 21:3047-3056.
    • (2001) Mol. Cell Biol. , vol.21 , pp. 3047-3056
    • Liu, Y.1    Jenkins, B.2    Shin, J.L.3    Rohrschneider, L.R.4
  • 14
    • 0028826595 scopus 로고
    • Colony-stimulating factor 1-induced STAT1 and STAT3 activation is accompanied by phosphorylation of Tyk2 in macrophages and Tyk2 and JAK1 in fibroblasts
    • Novak U., Harpur A.G., Paradiso L., Kanagasundaram V., Jaworowski A., Wilks A.F., Hamilton J.A. Colony-stimulating factor 1-induced STAT1 and STAT3 activation is accompanied by phosphorylation of Tyk2 in macrophages and Tyk2 and JAK1 in fibroblasts. Blood 1995, 86:2948-2956.
    • (1995) Blood , vol.86 , pp. 2948-2956
    • Novak, U.1    Harpur, A.G.2    Paradiso, L.3    Kanagasundaram, V.4    Jaworowski, A.5    Wilks, A.F.6    Hamilton, J.A.7
  • 15
    • 60849112820 scopus 로고    scopus 로고
    • Tumour cell survival signalling by the ERK1/2 pathway
    • Balmanno K., Cook S.J. Tumour cell survival signalling by the ERK1/2 pathway. Cell Death Differ. 2009, 16:368-377.
    • (2009) Cell Death Differ. , vol.16 , pp. 368-377
    • Balmanno, K.1    Cook, S.J.2
  • 16
    • 34248563290 scopus 로고    scopus 로고
    • The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition
    • Meloche S., Pouyssegur J. The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition. Oncogene 2007, 26:3227-3239.
    • (2007) Oncogene , vol.26 , pp. 3227-3239
    • Meloche, S.1    Pouyssegur, J.2
  • 17
    • 33747792064 scopus 로고    scopus 로고
    • MAPK signalling: ERK5 versus ERK1/2
    • Nishimoto S., Nishida E. MAPK signalling: ERK5 versus ERK1/2. EMBO Rep. 2006, 7:782-786.
    • (2006) EMBO Rep. , vol.7 , pp. 782-786
    • Nishimoto, S.1    Nishida, E.2
  • 20
    • 69949135616 scopus 로고    scopus 로고
    • ERK5 activity is required for nerve growth factor-induced neurite outgrowth and stabilization of tyrosine hydroxylase in PC12 cells
    • Obara Y., Yamauchi A., Takehara S., Nemoto W., Takahashi M., Stork P.J., Nakahata N. ERK5 activity is required for nerve growth factor-induced neurite outgrowth and stabilization of tyrosine hydroxylase in PC12 cells. J. Biol. Chem. 2009, 284:23564-23573.
    • (2009) J. Biol. Chem. , vol.284 , pp. 23564-23573
    • Obara, Y.1    Yamauchi, A.2    Takehara, S.3    Nemoto, W.4    Takahashi, M.5    Stork, P.J.6    Nakahata, N.7
  • 21
    • 84863623155 scopus 로고    scopus 로고
    • Inducible and conditional deletion of extracellular signal-regulated kinase 5 disrupts adult hippocampal neurogenesis
    • Pan Y.W., Zou J., Wang W., Sakagami H., Garelick M.G., Abel G., Kuo C.T., Storm D.R., Xia Z. Inducible and conditional deletion of extracellular signal-regulated kinase 5 disrupts adult hippocampal neurogenesis. J. Biol. Chem. 2012, 287:23306-23317.
    • (2012) J. Biol. Chem. , vol.287 , pp. 23306-23317
    • Pan, Y.W.1    Zou, J.2    Wang, W.3    Sakagami, H.4    Garelick, M.G.5    Abel, G.6    Kuo, C.T.7    Storm, D.R.8    Xia, Z.9
  • 22
    • 84873828916 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinase 5 (ERK5) mediates prolactin-stimulated adult neurogenesis in the subventricular zone and olfactory bulb
    • Wang W., Pan Y.W., Wietecha T., Zou J., Abel G.M., Kuo C.T., Xia Z. Extracellular signal-regulated kinase 5 (ERK5) mediates prolactin-stimulated adult neurogenesis in the subventricular zone and olfactory bulb. J. Biol. Chem. 2013, 288:2623-2631.
    • (2013) J. Biol. Chem. , vol.288 , pp. 2623-2631
    • Wang, W.1    Pan, Y.W.2    Wietecha, T.3    Zou, J.4    Abel, G.M.5    Kuo, C.T.6    Xia, Z.7
  • 23
    • 84893479546 scopus 로고    scopus 로고
    • Genetic activation of ERK5 MAP kinase enhances adult neurogenesis and extends hippocampus-dependent long-term memory
    • Wang W., Pan Y.W., Zou J., Li T., Abel G.M., Palmiter R.D., Storm D.R., Xia Z. Genetic activation of ERK5 MAP kinase enhances adult neurogenesis and extends hippocampus-dependent long-term memory. J. Neurosci. 2014, 34:2130-2147.
    • (2014) J. Neurosci. , vol.34 , pp. 2130-2147
    • Wang, W.1    Pan, Y.W.2    Zou, J.3    Li, T.4    Abel, G.M.5    Palmiter, R.D.6    Storm, D.R.7    Xia, Z.8
  • 24
    • 44849114794 scopus 로고    scopus 로고
    • ERK5/BMK1 is indispensable for optimal colony-stimulating factor 1 (CSF-1)-induced proliferation in macrophages in a Src-dependent fashion
    • Rovida E., Spinelli E., Sdelci S., Barbetti V., Morandi A., Giuntoli S., Sbarba P.Dello ERK5/BMK1 is indispensable for optimal colony-stimulating factor 1 (CSF-1)-induced proliferation in macrophages in a Src-dependent fashion. J. Immunol. 2008, 180:4166-4172.
    • (2008) J. Immunol. , vol.180 , pp. 4166-4172
    • Rovida, E.1    Spinelli, E.2    Sdelci, S.3    Barbetti, V.4    Morandi, A.5    Giuntoli, S.6    Sbarba, P.D.7
  • 27
    • 84896526361 scopus 로고    scopus 로고
    • ERK5 pathway regulates transcription factors important for monocytic differentiation of human myeloid leukemia cells
    • Wang X., Pesakhov S., Harrison J.S., Danilenko M., Studzinski G.P. ERK5 pathway regulates transcription factors important for monocytic differentiation of human myeloid leukemia cells. J. Cell Physiol. 2014, 229:856-867.
    • (2014) J. Cell Physiol. , vol.229 , pp. 856-867
    • Wang, X.1    Pesakhov, S.2    Harrison, J.S.3    Danilenko, M.4    Studzinski, G.P.5
  • 30
    • 0017155490 scopus 로고
    • Establishment and characterization of a human histiocytic lymphoma cell line (U-937)
    • Sundstrom C., Nilsson K. Establishment and characterization of a human histiocytic lymphoma cell line (U-937). Int. J. Cancer 1976, 17:565-577.
    • (1976) Int. J. Cancer , vol.17 , pp. 565-577
    • Sundstrom, C.1    Nilsson, K.2
  • 31
    • 0034491081 scopus 로고    scopus 로고
    • Mycoplasma detection in cell cultures: a comparison of four methods
    • Garner C.M., Hubbold L.M., Chakraborti P.R. Mycoplasma detection in cell cultures: a comparison of four methods. Br. J. Biomed. Sci. 2000, 57:295-301.
    • (2000) Br. J. Biomed. Sci. , vol.57 , pp. 295-301
    • Garner, C.M.1    Hubbold, L.M.2    Chakraborti, P.R.3
  • 32
    • 77957298685 scopus 로고    scopus 로고
    • 3-induced differentiation of human AML cells ex vivo and regulates the levels of differentiation-related transcription factors
    • 3-induced differentiation of human AML cells ex vivo and regulates the levels of differentiation-related transcription factors. Hematol. Oncol. 2010, 28:124-132.
    • (2010) Hematol. Oncol. , vol.28 , pp. 124-132
    • Zhang, J.1    Harrison, J.S.2    Uskokovic, M.3    Danilenko, M.4    Studzinski, G.P.5
  • 33
    • 0028296086 scopus 로고
    • Monocyte dysfunction in patients with Gaucher disease: evidence for interference of glucocerebroside with superoxide generation
    • Liel Y., Rudich A., Nagauker-Shriker O., Yermiyahu T., Levy R. Monocyte dysfunction in patients with Gaucher disease: evidence for interference of glucocerebroside with superoxide generation. Blood 1994, 83:2646-2653.
    • (1994) Blood , vol.83 , pp. 2646-2653
    • Liel, Y.1    Rudich, A.2    Nagauker-Shriker, O.3    Yermiyahu, T.4    Levy, R.5
  • 37
    • 84859768494 scopus 로고    scopus 로고
    • Molecular targeted therapy in acute myeloid leukemia
    • Daver N., Cortes J. Molecular targeted therapy in acute myeloid leukemia. Hematology 2012, 17(Suppl. 1):S59-62.
    • (2012) Hematology , vol.17 , pp. S59-62
    • Daver, N.1    Cortes, J.2
  • 39
    • 77949464718 scopus 로고    scopus 로고
    • From basic research to clinical development of MEK1/2 inhibitors for cancer therapy
    • Fremin C., Meloche S. From basic research to clinical development of MEK1/2 inhibitors for cancer therapy. J. Hematol. Oncol. 2010, 3:8.
    • (2010) J. Hematol. Oncol. , vol.3 , pp. 8
    • Fremin, C.1    Meloche, S.2
  • 40
    • 0033543549 scopus 로고    scopus 로고
    • Activation of the protein kinase ERK5/BMK1 by receptor tyrosine kinases. Identification and characterization of a signaling pathway to the nucleus
    • Kamakura S., Moriguchi T., Nishida E. Activation of the protein kinase ERK5/BMK1 by receptor tyrosine kinases. Identification and characterization of a signaling pathway to the nucleus. J. Biol. Chem. 1999, 274:26563-26571.
    • (1999) J. Biol. Chem. , vol.274 , pp. 26563-26571
    • Kamakura, S.1    Moriguchi, T.2    Nishida, E.3
  • 41
    • 80052025517 scopus 로고    scopus 로고
    • Inhibition of MEK5 by BIX02188 induces apoptosis in cells expressing the oncogenic mutant FLT3-ITD
    • Razumovskaya E., Sun J., Ronnstrand L. Inhibition of MEK5 by BIX02188 induces apoptosis in cells expressing the oncogenic mutant FLT3-ITD. Biochem. Biophys. Res. Commun. 2011, 412:307-312.
    • (2011) Biochem. Biophys. Res. Commun. , vol.412 , pp. 307-312
    • Razumovskaya, E.1    Sun, J.2    Ronnstrand, L.3
  • 42
    • 0035958732 scopus 로고    scopus 로고
    • Effects of MAP kinase cascade inhibitors on the MKK5/ERK5 pathway
    • Mody N., Leitch J., Armstrong C., Dixon J., Cohen P. Effects of MAP kinase cascade inhibitors on the MKK5/ERK5 pathway. FEBS Lett. 2001, 502:21-24.
    • (2001) FEBS Lett. , vol.502 , pp. 21-24
    • Mody, N.1    Leitch, J.2    Armstrong, C.3    Dixon, J.4    Cohen, P.5
  • 43
    • 0029031897 scopus 로고
    • Leukocyte CD11/CD18 integrins: biological and clinical relevance
    • Mazzone A., Ricevuti G. Leukocyte CD11/CD18 integrins: biological and clinical relevance. Haematologica 1995, 80:161-175.
    • (1995) Haematologica , vol.80 , pp. 161-175
    • Mazzone, A.1    Ricevuti, G.2
  • 44
    • 0018771246 scopus 로고
    • Induction of differentiation in human promyelocytic leukemia cells by tumor promoters
    • Rovera G., O'Brien T.G., Diamond L. Induction of differentiation in human promyelocytic leukemia cells by tumor promoters. Science 1979, 204:868-870.
    • (1979) Science , vol.204 , pp. 868-870
    • Rovera, G.1    O'Brien, T.G.2    Diamond, L.3
  • 45
    • 79959540002 scopus 로고    scopus 로고
    • CCAAT/enhancer-binding protein beta inhibits proliferation in monocytic cells by affecting the retinoblastoma protein/E2F/cyclin E pathway but is not directly required for macrophage morphology
    • Gutsch R., Kandemir J.D., Pietsch D., Cappello C., Meyer J., Simanowski K., Huber R., Brand K. CCAAT/enhancer-binding protein beta inhibits proliferation in monocytic cells by affecting the retinoblastoma protein/E2F/cyclin E pathway but is not directly required for macrophage morphology. J. Biol. Chem. 2011, 286:22716-22729.
    • (2011) J. Biol. Chem. , vol.286 , pp. 22716-22729
    • Gutsch, R.1    Kandemir, J.D.2    Pietsch, D.3    Cappello, C.4    Meyer, J.5    Simanowski, K.6    Huber, R.7    Brand, K.8
  • 46
    • 0030930897 scopus 로고    scopus 로고
    • Differential effects of phorbol ester on signaling and gene expression in human leukemia cells
    • Hass R., Prudovsky I., Kruhoffer M. Differential effects of phorbol ester on signaling and gene expression in human leukemia cells. Leuk. Res. 1997, 21:589-594.
    • (1997) Leuk. Res. , vol.21 , pp. 589-594
    • Hass, R.1    Prudovsky, I.2    Kruhoffer, M.3
  • 49
    • 0030013991 scopus 로고    scopus 로고
    • Differences in the state of differentiation of THP-1 cells induced by phorbol ester and 1,25-dihydroxyvitamin D3
    • Schwende H., Fitzke E., Ambs P., Dieter P. Differences in the state of differentiation of THP-1 cells induced by phorbol ester and 1,25-dihydroxyvitamin D3. J. Leukoc. Biol. 1996, 59:555-561.
    • (1996) J. Leukoc. Biol. , vol.59 , pp. 555-561
    • Schwende, H.1    Fitzke, E.2    Ambs, P.3    Dieter, P.4
  • 50
    • 0023605430 scopus 로고
    • The HL-60 promyelocytic leukemia cell line: proliferation, differentiation, and cellular oncogene expression
    • Collins S.J. The HL-60 promyelocytic leukemia cell line: proliferation, differentiation, and cellular oncogene expression. Blood 1987, 70:1233-1244.
    • (1987) Blood , vol.70 , pp. 1233-1244
    • Collins, S.J.1
  • 51
    • 0021837904 scopus 로고
    • A system for monocytic differentiation of leukemic cells HL 60 by a short exposure to 1,25-dihydroxycholecalciferol
    • Studzinski G.P., Bhandal A.K., Brelvi Z.S. A system for monocytic differentiation of leukemic cells HL 60 by a short exposure to 1,25-dihydroxycholecalciferol. Proc. Soc. Exp. Biol. Med. 1985, 179:288-295.
    • (1985) Proc. Soc. Exp. Biol. Med. , vol.179 , pp. 288-295
    • Studzinski, G.P.1    Bhandal, A.K.2    Brelvi, Z.S.3
  • 53
    • 0035062018 scopus 로고    scopus 로고
    • Evidence that activation of MEK1,2/erk1,2 signal transduction pathway is necessary for calcitriol-induced differentiation of HL-60 cells
    • Marcinkowska E. Evidence that activation of MEK1,2/erk1,2 signal transduction pathway is necessary for calcitriol-induced differentiation of HL-60 cells. Anticancer Res. 2001, 21:499-504.
    • (2001) Anticancer Res. , vol.21 , pp. 499-504
    • Marcinkowska, E.1
  • 54
    • 84874464126 scopus 로고    scopus 로고
    • Morphological analysis and differentiation of benign cystic neoplasms of the pancreas using computed tomography and magnetic resonance imaging
    • Grieser C., Heine G., Stelter L., Steffen I.G., Rothe J.H., Walter T.C., Fischer C., Bahra M., Denecke T. Morphological analysis and differentiation of benign cystic neoplasms of the pancreas using computed tomography and magnetic resonance imaging. RöFo - Fortschr. Rontg. 2013, 185:219-227.
    • (2013) RöFo - Fortschr. Rontg. , vol.185 , pp. 219-227
    • Grieser, C.1    Heine, G.2    Stelter, L.3    Steffen, I.G.4    Rothe, J.H.5    Walter, T.C.6    Fischer, C.7    Bahra, M.8    Denecke, T.9
  • 55
    • 0027430713 scopus 로고
    • Phenotypical and functional characterization of Fc gamma receptor I (CD64)-negative monocytes, a minor human monocyte subpopulation with high accessory and antiviral activity
    • Grage-Griebenow E., Lorenzen D., Fetting R., Flad H.D., Ernst M. Phenotypical and functional characterization of Fc gamma receptor I (CD64)-negative monocytes, a minor human monocyte subpopulation with high accessory and antiviral activity. Eur. J. Immunol. 1993, 23:3126-3135.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 3126-3135
    • Grage-Griebenow, E.1    Lorenzen, D.2    Fetting, R.3    Flad, H.D.4    Ernst, M.5
  • 56
    • 56749174940 scopus 로고    scopus 로고
    • Exploring the full spectrum of macrophage activation
    • Mosser D.M., Edwards J.P. Exploring the full spectrum of macrophage activation. Nat. Rev. Immunol. 2008, 8:958-969.
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 958-969
    • Mosser, D.M.1    Edwards, J.P.2
  • 57
    • 36249032544 scopus 로고    scopus 로고
    • The macrophage: past, present and future
    • Gordon S. The macrophage: past, present and future. Eur. J. Immunol. 2007, 37(Suppl 1):S9-17.
    • (2007) Eur. J. Immunol. , vol.37 , pp. S9-17
    • Gordon, S.1
  • 58
    • 0037119422 scopus 로고    scopus 로고
    • Accelerated phagocytosis of amyloid-beta by mouse and human microglia overexpressing the macrophage colony-stimulating factor receptor
    • Mitrasinovic O.M., Murphy G.M. Accelerated phagocytosis of amyloid-beta by mouse and human microglia overexpressing the macrophage colony-stimulating factor receptor. J. Biol. Chem. 2002, 277:29889-29896.
    • (2002) J. Biol. Chem. , vol.277 , pp. 29889-29896
    • Mitrasinovic, O.M.1    Murphy, G.M.2
  • 59
    • 0142012147 scopus 로고    scopus 로고
    • Microglial overexpression of the M-CSF receptor augments phagocytosis of opsonized Abeta
    • Mitrasinovic O.M., Murphy G.M. Microglial overexpression of the M-CSF receptor augments phagocytosis of opsonized Abeta. Neurobiol. Aging 2003, 24:807-815.
    • (2003) Neurobiol. Aging , vol.24 , pp. 807-815
    • Mitrasinovic, O.M.1    Murphy, G.M.2
  • 60
    • 84871051772 scopus 로고    scopus 로고
    • Epstein-Barr virus-encoded BARF1 protein is a decoy receptor for macrophage colony stimulating factor and interferes with macrophage differentiation and activation
    • Hoebe E.K., Le Large T.Y., Tarbouriech N., Oosterhoff D., De Gruijl T.D., Middeldorp J.M., Greijer A.E. Epstein-Barr virus-encoded BARF1 protein is a decoy receptor for macrophage colony stimulating factor and interferes with macrophage differentiation and activation. Viral Immunol. 2012, 25:461-470.
    • (2012) Viral Immunol. , vol.25 , pp. 461-470
    • Hoebe, E.K.1    Le Large, T.Y.2    Tarbouriech, N.3    Oosterhoff, D.4    De Gruijl, T.D.5    Middeldorp, J.M.6    Greijer, A.E.7
  • 62
    • 77649267205 scopus 로고    scopus 로고
    • The identification of markers of macrophage differentiation in PMA-stimulated THP-1 cells and monocyte-derived macrophages
    • Daigneault M., Preston J.A., Marriott H.M., Whyte M.K., Dockrell D.H. The identification of markers of macrophage differentiation in PMA-stimulated THP-1 cells and monocyte-derived macrophages. PLoS One 2010, 5:e8668.
    • (2010) PLoS One , vol.5 , pp. e8668
    • Daigneault, M.1    Preston, J.A.2    Marriott, H.M.3    Whyte, M.K.4    Dockrell, D.H.5
  • 63
    • 84876318758 scopus 로고    scopus 로고
    • Canonical and kinase activity-independent mechanisms for extracellular signal-regulated kinase 5 (ERK5) nuclear translocation require dissociation of Hsp90 from the ERK5-Cdc37 complex
    • Erazo T., Moreno A., Ruiz-Babot G., Rodriguez-Asiain A., Morrice N.A., Espadamala J., Bayascas J.R., Gomez N., Lizcano J.M. Canonical and kinase activity-independent mechanisms for extracellular signal-regulated kinase 5 (ERK5) nuclear translocation require dissociation of Hsp90 from the ERK5-Cdc37 complex. Mol. Cell Biol. 2013, 33:1671-1686.
    • (2013) Mol. Cell Biol. , vol.33 , pp. 1671-1686
    • Erazo, T.1    Moreno, A.2    Ruiz-Babot, G.3    Rodriguez-Asiain, A.4    Morrice, N.A.5    Espadamala, J.6    Bayascas, J.R.7    Gomez, N.8    Lizcano, J.M.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.