The GM-CSF receptor family: Mechanism of activation and implications for disease

Growth Factors

Volumn 30, Issue 2, 2012, Pages 63-75

  Hercus, Timothy R ^a   Broughton, Sophie E ^b   Ekert, Paul G ^c   Ramshaw, Hayley S ^a   Perugini, Michelle ^a   Grimbaldeston, Michele ^a   Woodcock, Joanna M ^a   Thomas, Daniel ^a   Pitson, Stuart ^a   Hughes, Timothy ^a   D'Andrea, Richard J ^a,d   Parker, Michael W ^b,e   Lopez, Angel F ^a  

^a SA PATHOLOGY   (Australia)

^b ST VINCENT'S INSTITUTE OF MEDICAL RESEARCH   (Australia)

^c WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^d QUEEN ELIZABETH HOSPITAL   (Australia)

^e UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Activation; cytokine; GM CSF; receptor; signaling

Indexed keywords

CD135 ANTIGEN; CYTARABINE; CYTOKINE; CYTOKINE RECEPTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR RECEPTOR; I KAPPA B KINASE; I KAPPA B KINASE ALPHA; IMATINIB; INTERLEUKIN 3; INTERLEUKIN 3 RECEPTOR; INTERLEUKIN 5; JANUS KINASE 2; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BCL 2; PROTEIN KINASE B; PROTEIN MCL 1; RECOMBINANT GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; RECOMBINANT INTERLEUKIN 3; STAT PROTEIN; STAT5 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING;

ACUTE GRANULOCYTIC LEUKEMIA; ANTIGEN PRESENTING CELL; APOPTOSIS; BASOPHIL; CANCER CHEMOTHERAPY; CELL ACTIVATION; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SURVIVAL; CHRONIC INFLAMMATION; CHRONIC MYELOID LEUKEMIA; COMPLEX FORMATION; CYTOKINE PRODUCTION; CYTOPLASM; GENE EXPRESSION; GENE MUTATION; HEMATOLOGIC MALIGNANCY; HUMAN; KINETICS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; RECEPTOR AFFINITY; REVIEW; SIGNAL TRANSDUCTION; TH2 CELL; TRANSACTIVATION; TREATMENT OUTCOME;

CHRONIC DISEASE; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HEMATOLOGIC NEOPLASMS; HUMANS; INFLAMMATION; MYELOID CELLS; RECEPTORS, GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; SIGNAL TRANSDUCTION;

EID: 84858976797     PISSN: 08977194     EISSN: 10292292     Source Type: Journal    
DOI: 10.3109/08977194.2011.649919     Document Type: Review

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