Potential effect of matrix stiffness on the enrichment of tumor initiating cells under three-dimensional culture conditions

Experimental Cell Research

Volumn 330, Issue 1, 2015, Pages 123-134

  Liu, Chang ^a,b   Liu, Yang ^a   Xu, Xiao xi ^a,b   Wu, Hao ^a,b   Xie, Hong guo ^a   Chen, Li ^a,b   Lu, Ting ^a   Yang, Li ^c   Guo, Xin ^a   Sun, Guang wei ^a   Wang, Wei ^a   Ma, Xiao jun ^a   He, Xin ^c  

^a DALIAN INSTITUTE OF CHEMICAL PHYSICS   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c DALIAN MEDICAL UNIVERSITY   (China)

Author keywords

Alginate gel beads; Matrix stiffness; Three dimensional culture; Tumor initiating cells

Indexed keywords

ALGINIC ACID; BREAST CANCER RESISTANCE PROTEIN; HERMES ANTIGEN; OCTAMER TRANSCRIPTION FACTOR 4; ORGANIC CATION TRANSPORTER 3; TRANSCRIPTION FACTOR NANOG; ABC TRANSPORTER; ABCG2 PROTEIN, HUMAN; HOMEODOMAIN PROTEIN; NANOG PROTEIN, HUMAN; POU5F1 PROTEIN, HUMAN; TUMOR PROTEIN;

ARTICLE; CANCER STEM CELL; CARCINOGENICITY; CELL CULTURE; CONTROLLED STUDY; DRUG RESISTANCE; GEL; GENE EXPRESSION; HEAD AND NECK SQUAMOUS CELL CARCINOMA; HUMAN; HUMAN CELL; MATRIX STIFFNESS; RIGIDITY; THREE DIMENSIONAL CULTURE; TUMOR INITIATING CELL; TUMOR MICROENVIRONMENT; CHEMISTRY; DRUG EFFECTS; EXTRACELLULAR MATRIX; GENETICS; HEAD AND NECK TUMOR; METABOLISM; SQUAMOUS CELL CARCINOMA; TUMOR CELL LINE;

ALGINATES; ANTIGENS, CD44; ATP-BINDING CASSETTE TRANSPORTERS; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; EXTRACELLULAR MATRIX; HEAD AND NECK NEOPLASMS; HOMEODOMAIN PROTEINS; HUMANS; NEOPLASM PROTEINS; NEOPLASTIC STEM CELLS; OCTAMER TRANSCRIPTION FACTOR-3; TUMOR MICROENVIRONMENT;

EID: 84916934752     PISSN: 00144827     EISSN: 10902422     Source Type: Journal    
DOI: 10.1016/j.yexcr.2014.07.036     Document Type: Article

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