CD44 interacts with EGFR and promotes head and neck squamous cell carcinoma initiation and progression

Oral Oncology

Volumn 49, Issue 4, 2013, Pages 306-313

  Perez, Aymee ^a   Neskey, David M ^a   Wen, Judy ^a   Pereira, Lutecia ^b   Reategui, Erika P ^b   Goodwin, W Jarrard ^a,b   Carraway, Kermit L ^a,b   Franzmann, Elizabeth J ^a,b  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MIAMI   (United States)

Author keywords

Cancer stem cells; CD44; Cell proliferation; Head and neck squamous cell carcinoma; Treatment resistance

Indexed keywords

CISPLATIN; EPIDERMAL GROWTH FACTOR RECEPTOR; HERMES ANTIGEN; SMALL INTERFERING RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER GROWTH; CANCER RESISTANCE; CANCER STEM CELL; CARCINOGENESIS; CASE REPORT; CELL MIGRATION; CELL POPULATION; CELL PROLIFERATION; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; DOWN REGULATION; DRUG SENSITIVITY; HEAD AND NECK SQUAMOUS CELL CARCINOMA; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE MICROSCOPY; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; STABLE TRANSFECTION; TUMOR PROMOTION; TUMOR XENOGRAFT; WESTERN BLOTTING;

ANTIGENS, CD44; BLOTTING, WESTERN; CARCINOMA, SQUAMOUS CELL; CELL TRANSFORMATION, NEOPLASTIC; DISEASE PROGRESSION; GENE SILENCING; HEAD AND NECK NEOPLASMS; HUMANS; IMMUNOHISTOCHEMISTRY; RECEPTOR, EPIDERMAL GROWTH FACTOR; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION;

EID: 84875265144     PISSN: 13688375     EISSN: 18790593     Source Type: Journal    
DOI: 10.1016/j.oraloncology.2012.11.009     Document Type: Article

References (35)

1. American Cancer Society Cancer facts and figures 2009 2010 American Cancer Society Atlanta
2. D.M. Parkin, F. Bray, J. Ferlay, and P. Pisani Global cancer statistics, 2002 CA Cancer J Clin 55 2005 74 108
3. C.P. Rodriguez, and D.J. Adelstein Survival trends in head and neck cancer: opportunities for improving outcomes Oncologist 15 2010 921 923
4. National Cancer Institute Fact Sheet Head and Neck Cancer: Questions and Answers (03/09/2005). < http://www.cancer.gov/cancertopics/factsheet/Sites- Types/head-and-neck > [retrieved 30.04.11].
5. C.R. Leemans, B.J. Braakhuis, and R.H. Brakenhoff The molecular biology of head and neck cancer Nat Rev Cancer 11 1 2011 9 22
6. J.B. Cooper, and E.E. Cohen Mechanisms of resistance to EGFR inhibitors in head and neck cancer Head Neck 31 8 2009 1086 1094
7. Rabinowits G, Haddad RI. Overcoming resistance to EGFR inhibitor in head and neck cancer: a review of the literature. Oral Oncol. 2012 July 25 [Epub ahead of print].
8. E.J. Franzmann, E.P. Reategui, K.L. Carraway, K.L. Hamilton, D.T. Weed, and W.J. Goodwin Salivary soluble CD44: a potential molecular marker for head and neck cancer Cancer Epidemiol Biomarkers Prev 14 3 2005 735 739
9. E.J. Franzmann, E.P. Reategui, F. Pedroso, F.G. Pernas, B.M. Karakullukcu, and K.L. Carraway Soluble CD44 is a potential marker for the early detection of head and neck cancer Cancer Epidemiol Biomarkers Prev 16 7 2007 1348 1355
10. E.J. Franzmann, E.P. Reategui, L.H. Pereira, F. Pedroso, D. Joseph, and G.O. Allen Salivary protein and solCD44 levels as a potential screening tool for early detection of head and neck squamous cell carcinoma Head Neck 34 5 2012 687 695
11. M.E. Prince, R. Sivanandan, A. Kaczorowski, G.T. Wolf, M.J. Kaplan, and P. Dalerba Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma Proc Natl Acad Sci USA 104 3 2007 973 978
12. J.D. Dias, K. Guse, P. Nokisalmi, M. Eriksson, D.T. Chen, and I. Diaconu Multimodal approach using oncolytic adenovirus, cetuximab, chemotherapy and radiotherapy in HNSCC low passage tumour cell lines Eur J Cancer 46 3 2010 625 635
13. G.R. Screaton, M.V. Bell, D.G. Jackson, F.B. Cornelis, U. Gerth, and J.I. Bell Genomic structure of DNA encoding the lymphocyte homing receptor CD44 reveals at least 12 alternatively spliced exons Proc Natl Acad Sci USA 89 24 1992 12160 12164
14. H. Ponta, L. Sherman, and P.A. Herrlich CD44: from adhesion molecules to signaling regulators Nat Rev Mol Cell Biol 4 1 2003 33 45
15. H. Morrison, L.S. Sherman, J. Legg, F. Banine, C. Isacke, and C.A. Haipek The NF2 tumor suppressor gene product, merlin, mediates contact inhibition of growth through interactions with CD44 Genes Dev 15 8 2001 968 980
16. V.B. Lokeshwar, N. Fregien, and L.Y. Bourguignon Ankyrin-binding domain of CD44(GP85) is required for the expression of hyaluronic acid-mediated adhesion function J Cell Biol 126 4 1994 1099 1109
17. W. Knudson The role of CD44 as a cell surface hyaluronan receptor during tumor invasion of connective tissue Front Biosci 3 1998 604 615
18. L.Y. Bourguignon, E. Gilad, A. Brightman, F. Diedrich, and P. Singleton Hyaluronan-CD44 interaction with leukemia-associated RhoGEF and epidermal growth factor receptor promotes Rho/Ras co-activation, phospholipase C epsilon-Ca2+ signaling, and cytoskeleton modification in head and neck squamous cell carcinoma cells J Bio Chem 281 20 2006 14026 14040
19. S.J. Wang, and L.Y. Bourguignon Hyaluronan and the interaction between CD44 and epidermal growth factor receptor in oncogenic signaling and chemotherapy resistance in head and neck cancer Arch Otolaryngol Head Neck Surg 132 7 2006 771 778
20. S. Misra, B.P. Toole, and S. Ghatak Hyaluronan constitutively regulates activation of multiple receptor tyrosine kinases in epithelial and carcinoma cell J Biol Chem 281 46 2006 34936 34941
21. J.G. Rheinwald, and M.A. Beckett Tumorigenic keratinocyte lines requiring anchorage and fibroblast support cultured from human squamous cell carcinomas Cancer Res 41 5 1981 1657 1663
22. L.H. Pereira, I.N. Adebisi, A. Perez, M. Wiebel, I. Reis, and R. Duncan Salivary markers and risk factor data: a multivariate modeling approach for head and neck squamous cell carcinoma detection Cancer Biomarkers 10 5 2011 241 249
23. E. Ioachim, D. Assimakopoulos, A.C. Goussia, D. Peschos, A. Skevas, and N.J. Agnantis Glycoprotein CD44 expression in benign, premalignant and malignant epithelial lesions of the larynx: an immunohistochemical study including correlation with Rb, p53, Ki-67 and PCNA Histol Histopathol 14 4 1999 1113 1118
24. P. Hirvikoski, R. Tammi, E. Kumpulainen, J. Virtaniemi, J.J. Parkkinen, and M. Tammi Irregular expression of hyaluronan and its CD44 receptor is associated with metastatic phenotype in laryngeal squamous cell carcinoma Virchows Arch 434 1 1999 37 44
25. D. Lindquist, A. Ahrlund-Richter, M. Tarján, T. Tot, and T. Dalianis Intense CD44 expression is a negative prognostic factor in tonsillar and base of tongue cancer Anticancer Res 32 1 2012 153 161
26. L.Y. Bourguignon, H. Zhu, A. Chu, N. Iida, L. Zhang, and M.C. Hung Interaction between the adhesion receptor, CD44, and the oncogene product, p185HER2, promotes human ovarian tumor cell activation J Biol Chem 272 44 1997 27913 27918
27. W. Bao, H.J. Fu, Q.S. Xie, L. Wang, R. Zhang, and Z.Y. Guo HER2 interacts with CD44 to up-regulate CXCR4 via epigenetic silencing of microRNA-139 in gastric cancer cells Gastroenterology 141 6 2011 2076 2087
28. J.A. Bonner, P.M. Harari, J. Giralt, N. Azarnia, D.M. Shin, and R.B. Cohen Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck N Engl J Med 354 6 2006 567 578
29. S.C. Lee, A. Lopez-Albaitero, and R.L. Ferris Immunotherapy of head and neck cancer using tumor-antigen-specific monoclonal antibodies Curr Oncol Rep 11 2 2009 156 162
30. H. Le Roy, T. Zuliani, I. Wlowczuk, N. Faivre, N. Jouy, and B. Masselot Asymmetric distribution of epidermal growth factor receptor directs the fate of normal and cancer keratinocytes in vitro Stem Cells Dev 19 2 2010 Feb 209 220
31. J.L. Lee, M.J. Wang, and Y.J. Chen Acetylation and activation of STAT3 mediated by nuclear translocation of CD44 J Cell Biol 185 6 2009 949 957
32. R. van der Voort, T.E. Taher, V.J. Wielenga, M. Spaargaren, R. Prevo, and L. Smith Heparan sulfate-modified CD44 promotes hepatocyte growth factor/scatter factor-induced signal transduction through the receptor tyrosine kinase c-Met J Biol Chem 274 10 1999 6499 6506
33. L. Sherman, D. Wainwright, H. Ponta, and P. Herrlich A splice variant of CD44 expressed in the apical ectodermal ridge presents fibroblast growth factors to limb mesenchyme and is required for limb outgrowth Genes Dev 12 7 1998 1058 1071
34. D.G. Jackson, J.I. Bell, R. Dickinson, J. Timans, J. Shields, and N. Whittle Proteoglycan forms of the lymphocyte homing CD44 are alternative spliced variants containing the v3 exon J Cell Biol 128 4 1995 673 685
35. K.L. Bennett, D.G. Jackson, J.C. Simon, E. Tanczos, R. Peach, and B. Modrell CD44 isoforms containing exon v3 are responsible for the presentation of heparin-binding growth factor J Cell Biol 128 4 1995 687 698