PARP-1 mediates LPS-induced HMGB1 release by macrophages through regulation of HMGB1 acetylation

Journal of Immunology

Volumn 193, Issue 12, 2014, Pages 6114-6123

  Yang, Zhiyong ^a   Li, Li ^a   Chen, Lijuan ^a   Yuan, Weiwei ^a   Dong, Liming ^a   Zhang, Yushun ^a   Wu, Heshui ^a   Wang, Chunyou ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; HIGH MOBILITY GROUP B1 PROTEIN; HISTONE ACETYLTRANSFERASE; HISTONE DEACETYLASE; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; REACTIVE OXYGEN METABOLITE; 3-AMINOBENZAMIDE; BENZAMIDE DERIVATIVE; FR 180204; MITOGEN ACTIVATED PROTEIN KINASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PARP1 PROTEIN, MOUSE; PYRAZOLE DERIVATIVE; PYRIDAZINE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BONE MARROW DERIVED MACROPHAGE; CELL NUCLEUS; CONTROLLED STUDY; CYTOPLASM; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME DEFICIENCY; ENZYME INHIBITION; ENZYME MECHANISM; ENZYME REGULATION; IN VITRO STUDY; INTRACELLULAR TRANSPORT; MOUSE; NONHUMAN; PROTEIN ACETYLATION; PROTEIN MODIFICATION; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; PROTEIN TRANSPORT; REGULATORY MECHANISM; UPREGULATION; ACETYLATION; ANIMAL; ANTAGONISTS AND INHIBITORS; BLOOD; DISEASE MODEL; DRUG EFFECTS; ENDOTOXEMIA; IMMUNOLOGY; MACROPHAGE; METABOLISM; MORTALITY; SIGNAL TRANSDUCTION;

ACETYLATION; ACETYLCYSTEINE; ANIMALS; BENZAMIDES; CELL NUCLEUS; CYTOPLASM; DISEASE MODELS, ANIMAL; ENDOTOXEMIA; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HISTONE ACETYLTRANSFERASES; HISTONE DEACETYLASES; HMGB1 PROTEIN; LIPOPOLYSACCHARIDES; MACROPHAGES; MAP KINASE SIGNALING SYSTEM; MICE; POLY(ADP-RIBOSE) POLYMERASES; PROTEIN TRANSPORT; PYRAZOLES; PYRIDAZINES; REACTIVE OXYGEN SPECIES;

EID: 84916886836     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1400359     Document Type: Article

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