Wnt signaling induces gene expression of factors associated with bone destruction in lung and breast cancer

Clinical and Experimental Metastasis

Volumn 31, Issue 8, 2014, Pages 945-959

  Johnson, Rachelle W ^a,b,c   Merkel, Alyssa R ^a,c   Page, Jonathan M ^d   Ruppender, Nazanin S ^c,d   Guelcher, Scott A ^c,d   Sterling, Julie A ^a,b,c  

^a DEPARTMENT OF VETERANS AFFAIRS   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^d VANDERBILT UNIVERSITY   (United States)

Author keywords

Bone metastasis; Gli; Osteolysis; PTHrP; Rigidity; Wnt

Indexed keywords

BETA CATENIN; LITHIUM CHLORIDE; MESSENGER RNA; PARATHYROID HORMONE RELATED PROTEIN; SMAD PROTEIN; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI2; TRANSFORMING GROWTH FACTOR BETA; WNT PROTEIN; WNT3A PROTEIN; GLI2 PROTEIN, HUMAN; KRUPPEL LIKE FACTOR; NUCLEAR PROTEIN; SMALL INTERFERING RNA; WNT3A PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOCRINE EFFECT; BINDING SITE; BONE DESTRUCTION; BONE METASTASIS; BREAST CANCER; CANCER INHIBITION; CELL NUCLEUS; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GENE INDUCTION; GENE MUTATION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LUNG CANCER; MOUSE; NONHUMAN; OSTEOLYSIS; PARACRINE SIGNALING; POLYMERASE CHAIN REACTION; PROMOTER REGION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; STROMA CELL; TUMOR MICROENVIRONMENT; ANIMAL; ANTAGONISTS AND INHIBITORS; BONE TUMOR; BREAST TUMOR; DRUG SCREENING; GENE EXPRESSION REGULATION; GENETICS; LUNG TUMOR; METABOLISM; NUDE MOUSE; PATHOLOGY; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL CULTURE; WESTERN BLOTTING;

ANIMALS; BETA CATENIN; BLOTTING, WESTERN; BONE NEOPLASMS; BREAST NEOPLASMS; FEMALE; GENE EXPRESSION REGULATION; HUMANS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; LUNG NEOPLASMS; MICE; MICE, NUDE; NUCLEAR PROTEINS; PARATHYROID HORMONE-RELATED PROTEIN; PROMOTER REGIONS, GENETIC; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; STROMAL CELLS; TRANSFORMING GROWTH FACTOR BETA; TUMOR CELLS, CULTURED; WNT3A PROTEIN; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84916885452     PISSN: 02620898     EISSN: 15737276     Source Type: Journal    
DOI: 10.1007/s10585-014-9682-1     Document Type: Article

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