CRISPR-Cas9-based knockout of the prion protein and its effect on the Proteome

PLoS ONE

Volumn 9, Issue 12, 2014, Pages

  Mehrabian, Mohadeseh ^a,b   Brethour, Dylan ^a,b   Macisaac, Sarah ^a   Kim, Jin Kyu ^a   Gunawardana, C Geeth ^a   Wang, Hansen ^a   Schmitt Ulms, Gerold ^c  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

PRION PROTEIN; PROTEOME; PRION;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CRISPR CAS SYSTEM; CRISPR CAS9 SYSTEM; GENE SILENCING; MOLECULAR RECOGNITION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN ANALYSIS; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; VALIDATION PROCESS; ANIMAL; CELL LINE; GENE EXPRESSION PROFILING; GENE INACTIVATION; GENETICS; PRION; VALIDATION STUDY;

ANIMALS; CELL LINE; CRISPR-CAS SYSTEMS; GENE EXPRESSION PROFILING; GENE KNOCKOUT TECHNIQUES; MICE; PRIONS; PROTEOME;

EID: 84916620478     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0114594     Document Type: Article

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