Deletion of the gene encoding G0/G1 switch protein 2 (G0s2) alleviates high-fat-diet-induced weight gain and insulin resistance, and promotes browning of white adipose tissue in mice

Diabetologia

Volumn 58, Issue 1, 2015, Pages 149-157

  El Assaad, Wissal ^a   El Kouhen, Karim ^a   Mohammad, Amro H ^b   Yang, Jieyi ^b   Morita, Masahiro ^a   Gamache, Isabelle ^a   Mamer, Orval ^a   Avizonis, Daina ^a   Hermance, Nicole ^c   Kersten, Sander ^d   Tremblay, Michel L ^a,b   Kelliher, Michelle A ^c   Teodoro, Jose G ^a,b  

^a MCGILL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c UNIVERSITY OF MASSACHUSETTS   (United States)

^d WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

Adipose tissue browning; ATGL; Energy expenditure; G0s2; High fat diet; Insulin resistance; Lipolysis; Obesity; Thermogenesis

Indexed keywords

TRIACYLGLYCEROL LIPASE; CELL CYCLE PROTEIN; G0S2 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY COMPOSITION; BODY WEIGHT; BROWN ADIPOSE TISSUE; COLD TOLERANCE; CONTROLLED STUDY; ENERGY EXPENDITURE; ENERGY METABOLISM; FEMALE; FOOD INTAKE; G0S2 GENE; GENE; GENE DELETION; GENE EXPRESSION; GLUCOSE TOLERANCE TEST; INSULIN RESISTANCE; INSULIN TOLERANCE TEST; LIPID DIET; LIPID METABOLISM; LIPID STORAGE; LIPOLYSIS; MALE; MOUSE; NONHUMAN; THERMOGENESIS; WEIGHT GAIN; WHITE ADIPOSE TISSUE; ADVERSE EFFECTS; ANIMAL; BROWN ADIPOCYTE; CELL TRANSDIFFERENTIATION; GENETICS; KNOCKOUT MOUSE; OBESITY; PHYSIOLOGY;

ADIPOCYTES, BROWN; ADIPOSE TISSUE, WHITE; ADIPOSITY; ANIMALS; CELL CYCLE PROTEINS; CELL TRANSDIFFERENTIATION; DIET, HIGH-FAT; ENERGY METABOLISM; FEMALE; GENE DELETION; INSULIN RESISTANCE; MALE; MICE; MICE, KNOCKOUT; THERMOGENESIS; WEIGHT GAIN;

EID: 84916595427     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-014-3429-z     Document Type: Article

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