Retraction: p53 suppresses stress-induced cellular senescence via regulation of autophagy under the deprivation of serum (Molecular Medicine Reports (2015) 11 (1214-1220) DOI: 10.3892/mmr.2014.2853);P53 suppresses stress-induced cellular senescence via regulation of autophagy under the deprivation of serum

Molecular Medicine Reports

Volumn 11, Issue 2, 2015, Pages 1214-1220

  Sui, Xinbing ^a   Fang, Yong ^a   Lou, Haizhou ^a   Wang, Kaifeng ^a   Zheng, Yu ^a   Lou, Fang ^a   Jin, Wei ^a   Xu, Yinghua ^a   Chen, Wei ^a   Pan, Hongming ^a   Wang, Xian ^a   Han, Weidong ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

Autophagy; Cell cycle; Mtor; P53; Senescence

Indexed keywords

MAMMALIA;

3-METHYLADENINE; ADENINE; CULTURE MEDIUM; PROTEIN P53; TARGET OF RAPAMYCIN KINASE;

ANALOGS AND DERIVATIVES; AUTOPHAGY; CELL AGING; CULTURE MEDIUM; DRUG EFFECTS; G1 PHASE CELL CYCLE CHECKPOINT; GENETICS; HCT116 CELL LINE; HUMAN; MECHANICAL STRESS; METABOLISM; PHARMACOLOGY; PHOSPHORYLATION;

ADENINE; AUTOPHAGY; CELL AGING; CULTURE MEDIA, SERUM-FREE; G1 PHASE CELL CYCLE CHECKPOINTS; HCT116 CELLS; HUMANS; PHOSPHORYLATION; STRESS, MECHANICAL; TOR SERINE-THREONINE KINASES; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84916231270     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2020.11474     Document Type: Erratum

References (33)

1. Lane DP: Cancer. p53, guardian of the genome. Nature 358: 15-16, 1992.
2. Levine AJ: p53, the cellular gatekeeper for growth and division. Cell 88: 323-331, 1997.
3. Soussi T and Wiman KG: Shaping genetic alterations in human cancer: the p53 mutation paradigm. Cancer Cell 12: 303-312, 2007.
4. Zilfou JT and Lowe SW: Tumor suppressive functions of p53. Cold Spring Harb Perspect Biol 1: a001883, 2009.
5. Vousden KH and Ryan KM: p53 and metabolism. Nat Rev Cancer 9: 691-700, 2009.
6. Abida WM and Gu W: p53-Dependent and p53-independent activation of autophagy by ARF. Cancer Res 68: 352-357, 2008.
7. Tasdemir E, Maiuri MC, Galluzzi L, et al: Regulation of autophagy by cytoplasmic p53. Nat Cell Biol 10: 676-687, 2008.
8. Xue W, Zender L, Miething C, et al: Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas. Nature 445: 656-660, 2007.
9. Sui X, Jin L, Huang X, Geng S, He C and Hu X: p53 signaling and autophagy in cancer: a revolutionary strategy could be developed for cancer treatment. Autophagy 7: 565-571, 2011.
10. Kondo Y, Kanzawa T, Sawaya R and Kondo S: The role of autophagy in cancer development and response to therapy. Nat Rev Cancer 5: 726-734, 2005.
11. Yang Z and Klionsky DJ: An overview of the molecular mechanism of autophagy. Curr Top Microbiol Immunol 335: 1-32, 2009.
12. Lum JJ, DeBerardinis RJ and Thompson CB: Autophagy in metazoans: cell survival in the land of plenty. Nat Rev Mol Cell Biol 6: 439-448, 2005.
13. Scherz-Shouval R, Weidberg H, Gonen C, Wilder S, Elazar Z and Oren M: p53-dependent regulation of autophagy protein LC3 supports cancer cell survival under prolonged starvation. Proc Natl Acad Sci USA 107: 18511-18516, 2010.
14. Mizushima N, Levine B, Cuervo AM and Klionsky DJ: Autophagy fights disease through cellular self-digestion. Nature 451: 1069-1075, 2008.
15. Chen Z, Trotman LC, Shaffer D, et al: Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis. Nature 436: 725-730, 2005.
16. Ferbeyre G, de Stanchina E, Lin AW, et al: Oncogenic ras and p53 cooperate to induce cellular senescence. Mol Cell Biol 22: 3497-3508, 2002.
17. Lin HK, Chen Z, Wang G, et al: Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence. Nature 464: 374-379, 2010.
18. Santoro R and Blandino G: p53: The pivot between cell cycle arrest and senescence. Cell Cycle 9: 4262-4263, 2010.
19. Demidenko ZN, Korotchkina LG, Gudkov AV and Blagosklonny MV: Paradoxical suppression of cellular senescence by p53. Proc Natl Acad Sci USA 107: 9660-9664, 2010.
20. Pan H, Wang Z, Jiang L, et al: Autophagy inhibition sensitizes hepatocellular carcinoma to the multikinase inhibitor linifanib. Sci Rep 4: 6683, 2014.
21. Sui X, Kong N, Wang X, et al: JNK confers 5-fluorouracil resistance in p53-expressing colon cancer cells by inducing survival autophagy. Sci Rep 4: 4694, 2014.
22. Rzymski T, Milani M, Pike L, et al: Regulation of autophagy by ATF4 in response to severe hypoxia. Oncogene 29: 4424-4435, 2010.
23. Serrano M: Shifting senescence into quiescence by turning up p53. Cell Cycle 9: 4256-4257, 2010.
24. Fujita K, Horikawa I, Mondal AM, et al: Positive feedback between p53 and TRF2 during telomere-damage signaling and cellular senescence. Nat Cell Biol 12: 1205-1212, 2010.
25. Alcorta DA, Xiong Y, Phelps D, Hannon G, Beach D and Barrett JC: Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts. Proc Natl Acad Sci USA 93: 13742-13747, 1996.
26. Kang JY, Kim JJ, Jang SY and Bae YS: The p53-p21(Cip1/WAF1) pathway is necessary for cellular senescence induced by the inhibition of protein kinase CKII in human colon cancer cells. Mol Cells 28: 489-494, 2009.
27. Korotchkina LG, Leontieva OV, Bukreeva EI, Demidenko ZN, Gudkov AV and Blagosklonny MV: The choice between p53-induced senescence and quiescence is determined in part by the mTOR pathway. Aging (Albany NY) 2: 344-352, 2010.
28. Zoncu R, Efeyan A and Sabatini DM: mTOR: from growth signal integration to cancer, diabetes and ageing. Nat Rev Mol Cell Biol 12: 21-35, 2011.
29. Demidenko ZN and Blagosklonny MV: Growth stimulation leads to cellular senescence when the cell cycle is blocked. Cell Cycle 7: 3355-3361, 2008.
30. Feng Z, Hu W, de Stanchina E, et al: The regulation of AMPK beta1, TSC2, and PTEN expression by p53: stress, cell and tissue specificity, and the role of these gene products in modulating the IGF-1-AKT-mTOR pathways. Cancer Res 67: 3043-3053, 2007.
31. Budanov AV and Karin M: p53 target genes sestrin1 and sestrin2 connect genotoxic stress and mTOR signaling. Cell 134: 451-460, 2008.
32. Levine B and Abrams J: p53: The Janus of autophagy? Nat Cell Biol 10: 637-639, 2008.
33. Feng Z and Levine AJ: The regulation of energy metabolism and the IGF-1/mTOR pathways by the p53 protein. Trends Cell Biol 20: 427-434, 2010.