-
1
-
-
79952284127
-
Hallmarks of cancer: the next generation
-
Hanahan D., Weinberg R.A. Hallmarks of cancer: the next generation. Cell 2011, 144:646-674.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
2
-
-
84891759536
-
The role of reduced intracellular concentrations of active drugs in the lack of response to anticancer chemotherapy
-
Marin J.J., Monte M.J., Blazquez A.G., Macias R.I., Serrano M.A., Briz O. The role of reduced intracellular concentrations of active drugs in the lack of response to anticancer chemotherapy. Acta Pharmacol Sin 2014, 35:1-10.
-
(2014)
Acta Pharmacol Sin
, vol.35
, pp. 1-10
-
-
Marin, J.J.1
Monte, M.J.2
Blazquez, A.G.3
Macias, R.I.4
Serrano, M.A.5
Briz, O.6
-
3
-
-
84916206160
-
Advances and new perspectives in the treatment of metastatic colon cancer
-
Recondo G.J., Diaz-Canton E., de la Vega M., Greco M., Recondo G.S., Valsecchi M.E. Advances and new perspectives in the treatment of metastatic colon cancer. World J Gastrointest Oncol 2014, 6:211-224.
-
(2014)
World J Gastrointest Oncol
, vol.6
, pp. 211-224
-
-
Recondo, G.J.1
Diaz-Canton, E.2
de la Vega, M.3
Greco, M.4
Recondo, G.S.5
Valsecchi, M.E.6
-
5
-
-
37549034571
-
Non-invasive imaging correlates with histological and molecular characteristics of an osteosarcoma model: application for early detection and follow-up of MDR phenotype
-
Dutour A., Leclers D., Monteil J., Paraf F., Charissoux J.L., Rousseau R., et al. Non-invasive imaging correlates with histological and molecular characteristics of an osteosarcoma model: application for early detection and follow-up of MDR phenotype. Anticancer Res 2007, 27:4171-4178.
-
(2007)
Anticancer Res
, vol.27
, pp. 4171-4178
-
-
Dutour, A.1
Leclers, D.2
Monteil, J.3
Paraf, F.4
Charissoux, J.L.5
Rousseau, R.6
-
6
-
-
84872028852
-
The biology of brain metastasis
-
Langley R.R., Fidler I.J. The biology of brain metastasis. Clin Chem 2013, 59:180-189.
-
(2013)
Clin Chem
, vol.59
, pp. 180-189
-
-
Langley, R.R.1
Fidler, I.J.2
-
7
-
-
33847212780
-
Drug resistance in melanoma: new perspectives
-
La Porta C.A. Drug resistance in melanoma: new perspectives. Curr Med Chem 2007, 14:387-391.
-
(2007)
Curr Med Chem
, vol.14
, pp. 387-391
-
-
La Porta, C.A.1
-
8
-
-
84871509846
-
Intrinsic properties of tumour cells have a key impact on the bystander effect mediated by genetically engineered mesenchymal stromal cells
-
Matuskova M., Baranovicova L., Kozovska Z., Durinikova E., Pastorakova A., Hunakova L., et al. Intrinsic properties of tumour cells have a key impact on the bystander effect mediated by genetically engineered mesenchymal stromal cells. J Gene Med 2012, 14:776-787.
-
(2012)
J Gene Med
, vol.14
, pp. 776-787
-
-
Matuskova, M.1
Baranovicova, L.2
Kozovska, Z.3
Durinikova, E.4
Pastorakova, A.5
Hunakova, L.6
-
9
-
-
84859111006
-
Human adipose tissue-derived mesenchymal stem cells expressing yeast cytosinedeaminase: uracil phosphoribosyltransferase inhibit intracerebral rat glioblastoma
-
Altanerova V., Cihova M., Babic M., Rychly B., Ondicova K., Mravec B., et al. Human adipose tissue-derived mesenchymal stem cells expressing yeast cytosinedeaminase: uracil phosphoribosyltransferase inhibit intracerebral rat glioblastoma. Int J Cancer 2012, 130:2455-2463.
-
(2012)
Int J Cancer
, vol.130
, pp. 2455-2463
-
-
Altanerova, V.1
Cihova, M.2
Babic, M.3
Rychly, B.4
Ondicova, K.5
Mravec, B.6
-
10
-
-
84855280129
-
Increased proliferation and chemosensitivity of human mesenchymal stromal cells expressing fusion yeast cytosine deaminase
-
Kucerova L., Poturnajova M., Tyciakova S., Matuskova M. Increased proliferation and chemosensitivity of human mesenchymal stromal cells expressing fusion yeast cytosine deaminase. Stem Cell Res 2012, 8:247-258.
-
(2012)
Stem Cell Res
, vol.8
, pp. 247-258
-
-
Kucerova, L.1
Poturnajova, M.2
Tyciakova, S.3
Matuskova, M.4
-
11
-
-
77249122967
-
HSV-tk expressing mesenchymal stem cells exert bystander effect on human glioblastoma cells
-
Matuskova M., Hlubinova K., Pastorakova A., Hunakova L., Altanerova V., Altaner C., et al. HSV-tk expressing mesenchymal stem cells exert bystander effect on human glioblastoma cells. Cancer Lett 2010, 290:58-67.
-
(2010)
Cancer Lett
, vol.290
, pp. 58-67
-
-
Matuskova, M.1
Hlubinova, K.2
Pastorakova, A.3
Hunakova, L.4
Altanerova, V.5
Altaner, C.6
-
12
-
-
84901591109
-
Mesenchymal stromal cells retrovirally transduced with prodrug-converting genes are suitable vehicles for cancer gene therapy
-
Durinikova E., Kucerova L., Matuskova M. Mesenchymal stromal cells retrovirally transduced with prodrug-converting genes are suitable vehicles for cancer gene therapy. Acta Virol 2014, 58:1-13.
-
(2014)
Acta Virol
, vol.58
, pp. 1-13
-
-
Durinikova, E.1
Kucerova, L.2
Matuskova, M.3
-
13
-
-
0025312728
-
A genetic model for colorectal tumorigenesis
-
Fearon E.R., Vogelstein B. A genetic model for colorectal tumorigenesis. Cell 1990, 61:759-767.
-
(1990)
Cell
, vol.61
, pp. 759-767
-
-
Fearon, E.R.1
Vogelstein, B.2
-
14
-
-
0018864610
-
The pathogenesis of cancer metastasis
-
Poste G., Fidler I.J. The pathogenesis of cancer metastasis. Nature 1980, 283:139-146.
-
(1980)
Nature
, vol.283
, pp. 139-146
-
-
Poste, G.1
Fidler, I.J.2
-
15
-
-
33745612099
-
Stochastic cancer progression driven by non-clonal chromosome aberrations
-
Heng H.H., Stevens J.B., Liu G., Bremer S.W., Ye K.J., Reddy P.V., et al. Stochastic cancer progression driven by non-clonal chromosome aberrations. J Cell Physiol 2006, 208:461-472.
-
(2006)
J Cell Physiol
, vol.208
, pp. 461-472
-
-
Heng, H.H.1
Stevens, J.B.2
Liu, G.3
Bremer, S.W.4
Ye, K.J.5
Reddy, P.V.6
-
17
-
-
84857671060
-
Tumor heterogeneity: mechanisms and bases for a reliable application of molecular marker design
-
Diaz-Cano S.J. Tumor heterogeneity: mechanisms and bases for a reliable application of molecular marker design. Int J Mol Sci 2012, 13:1951-2011.
-
(2012)
Int J Mol Sci
, vol.13
, pp. 1951-2011
-
-
Diaz-Cano, S.J.1
-
18
-
-
34547193404
-
Phenotypic characterization of human colorectal cancer stem cells
-
Dalerba P., Dylla S.J., Park I.K., Liu R., Wang X., Cho R.W., et al. Phenotypic characterization of human colorectal cancer stem cells. Proc Natl Acad Sci U S A 2007, 104:10158-10163.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 10158-10163
-
-
Dalerba, P.1
Dylla, S.J.2
Park, I.K.3
Liu, R.4
Wang, X.5
Cho, R.W.6
-
19
-
-
0021242388
-
Tumor heterogeneity
-
Heppner G.H. Tumor heterogeneity. Cancer Res 1984, 44:2259-2265.
-
(1984)
Cancer Res
, vol.44
, pp. 2259-2265
-
-
Heppner, G.H.1
-
20
-
-
34548831213
-
The biology of cancer stem cells
-
Lobo N.A., Shimono Y., Qian D., Clarke M.F. The biology of cancer stem cells. Annu Rev Cell Dev Biol 2007, 23:675-699.
-
(2007)
Annu Rev Cell Dev Biol
, vol.23
, pp. 675-699
-
-
Lobo, N.A.1
Shimono, Y.2
Qian, D.3
Clarke, M.F.4
-
21
-
-
33947433676
-
Cancer stem cells: at the headwaters of tumor development
-
Ward R.J., Dirks P.B. Cancer stem cells: at the headwaters of tumor development. Annu Rev Pathol 2007, 2:175-189.
-
(2007)
Annu Rev Pathol
, vol.2
, pp. 175-189
-
-
Ward, R.J.1
Dirks, P.B.2
-
22
-
-
43749084585
-
Recent advances in cancer stem cells
-
Cho R.W., Clarke M.F. Recent advances in cancer stem cells. Curr Opin Genet Dev 2008, 18:48-53.
-
(2008)
Curr Opin Genet Dev
, vol.18
, pp. 48-53
-
-
Cho, R.W.1
Clarke, M.F.2
-
23
-
-
33745600820
-
Asymmetric and symmetric stem-cell divisions in development and cancer
-
Morrison S.J., Kimble J. Asymmetric and symmetric stem-cell divisions in development and cancer. Nature 2006, 441:1068-1074.
-
(2006)
Nature
, vol.441
, pp. 1068-1074
-
-
Morrison, S.J.1
Kimble, J.2
-
24
-
-
0037080188
-
A genetic determinant that specifically regulates the frequency of hematopoietic stem cells
-
Morrison S.J., Qian D., Jerabek L., Thiel B.A., Park I.K., Ford P.S., et al. A genetic determinant that specifically regulates the frequency of hematopoietic stem cells. J Immunol 2002, 168:635-642.
-
(2002)
J Immunol
, vol.168
, pp. 635-642
-
-
Morrison, S.J.1
Qian, D.2
Jerabek, L.3
Thiel, B.A.4
Park, I.K.5
Ford, P.S.6
-
25
-
-
79952993517
-
Multidrug efflux pumps and cancer stem cells: insights into multidrug resistance and therapeutic development
-
Moitra K., Lou H., Dean M. Multidrug efflux pumps and cancer stem cells: insights into multidrug resistance and therapeutic development. Clin Pharmacol Ther 2011, 89:491-502.
-
(2011)
Clin Pharmacol Ther
, vol.89
, pp. 491-502
-
-
Moitra, K.1
Lou, H.2
Dean, M.3
-
26
-
-
33846100356
-
A human colon cancer cell capable of initiating tumour growth in immunodeficient mice
-
O'Brien C.A., Pollett A., Gallinger S., Dick J.E. A human colon cancer cell capable of initiating tumour growth in immunodeficient mice. Nature 2007, 445:106-110.
-
(2007)
Nature
, vol.445
, pp. 106-110
-
-
O'Brien, C.A.1
Pollett, A.2
Gallinger, S.3
Dick, J.E.4
-
27
-
-
33846095137
-
Identification and expansion of human colon-cancer-initiating cells
-
Ricci-Vitiani L., Lombardi D.G., Pilozzi E., Biffoni M., Todaro M., Peschle C., et al. Identification and expansion of human colon-cancer-initiating cells. Nature 2007, 445:111-115.
-
(2007)
Nature
, vol.445
, pp. 111-115
-
-
Ricci-Vitiani, L.1
Lombardi, D.G.2
Pilozzi, E.3
Biffoni, M.4
Todaro, M.5
Peschle, C.6
-
28
-
-
65949112714
-
Aldehyde dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (SC) and tracks SC overpopulation during colon tumorigenesis
-
Huang E.H., Hynes M.J., Zhang T., Ginestier C., Dontu G., Appelman H., et al. Aldehyde dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (SC) and tracks SC overpopulation during colon tumorigenesis. Cancer Res 2009, 69:3382-3389.
-
(2009)
Cancer Res
, vol.69
, pp. 3382-3389
-
-
Huang, E.H.1
Hynes, M.J.2
Zhang, T.3
Ginestier, C.4
Dontu, G.5
Appelman, H.6
-
29
-
-
84863843869
-
A subpopulation of CD24(+) cells in colon cancer cell lines possess stem cell characteristics
-
Ke J., Wu X., He X., Lian L., Zou Y., Wang H., et al. A subpopulation of CD24(+) cells in colon cancer cell lines possess stem cell characteristics. Neoplasma 2012, 59:282-288.
-
(2012)
Neoplasma
, vol.59
, pp. 282-288
-
-
Ke, J.1
Wu, X.2
He, X.3
Lian, L.4
Zou, Y.5
Wang, H.6
-
30
-
-
80051800347
-
Colorectal Cancer Stem Cells: Biology and Therapeutic Implications
-
Wilson B.J., Schatton T., Frank M.H., Frank N.Y. Colorectal Cancer Stem Cells: Biology and Therapeutic Implications. Curr Colorectal Cancer Rep 2011, 7:128-135.
-
(2011)
Curr Colorectal Cancer Rep
, vol.7
, pp. 128-135
-
-
Wilson, B.J.1
Schatton, T.2
Frank, M.H.3
Frank, N.Y.4
-
31
-
-
51649111430
-
Single-cell cloning of colon cancer stem cells reveals a multi-lineage differentiation capacity
-
Vermeulen L., Todaro M., de Sousa Mello F., Sprick M.R., Kemper K., Perez Alea M., et al. Single-cell cloning of colon cancer stem cells reveals a multi-lineage differentiation capacity. Proc Natl Acad Sci U S A 2008, 105:13427-13432.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 13427-13432
-
-
Vermeulen, L.1
Todaro, M.2
de Sousa Mello, F.3
Sprick, M.R.4
Kemper, K.5
Perez Alea, M.6
-
32
-
-
77649272778
-
CD133 expression predicts for non-response to chemotherapy in colorectal cancer
-
Ong C.W., Kim L.G., Kong H.H., Low L.Y., Iacopetta B., Soong R., et al. CD133 expression predicts for non-response to chemotherapy in colorectal cancer. Mod Pathol 2010, 23:450-457.
-
(2010)
Mod Pathol
, vol.23
, pp. 450-457
-
-
Ong, C.W.1
Kim, L.G.2
Kong, H.H.3
Low, L.Y.4
Iacopetta, B.5
Soong, R.6
-
33
-
-
58149269566
-
CD44 is of functional importance for colorectal cancer stem cells
-
Du L., Wang H., He L., Zhang J., Ni B., Wang X., et al. CD44 is of functional importance for colorectal cancer stem cells. Clin Cancer Res 2008, 14:6751-6760.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 6751-6760
-
-
Du, L.1
Wang, H.2
He, L.3
Zhang, J.4
Ni, B.5
Wang, X.6
-
34
-
-
32444448861
-
Analysis and update of the human aldehyde dehydrogenase (ALDH) gene family
-
Vasiliou V., Nebert D.W. Analysis and update of the human aldehyde dehydrogenase (ALDH) gene family. Hum Genomics 2005, 2:138-143.
-
(2005)
Hum Genomics
, vol.2
, pp. 138-143
-
-
Vasiliou, V.1
Nebert, D.W.2
-
35
-
-
78650455641
-
Targeting aldehyde dehydrogenase cancer stem cells in ovarian cancer
-
Landen C.N., Goodman B., Katre A.A., Steg A.D., Nick A.M., Stone R.L., et al. Targeting aldehyde dehydrogenase cancer stem cells in ovarian cancer. Mol Cancer Ther 2010, 9:3186-3199.
-
(2010)
Mol Cancer Ther
, vol.9
, pp. 3186-3199
-
-
Landen, C.N.1
Goodman, B.2
Katre, A.A.3
Steg, A.D.4
Nick, A.M.5
Stone, R.L.6
-
36
-
-
79955025420
-
The role of human aldehyde dehydrogenase in normal and cancer stem cells
-
Ma I., Allan A.L. The role of human aldehyde dehydrogenase in normal and cancer stem cells. Stem Cell Rev 2011, 7:292-306.
-
(2011)
Stem Cell Rev
, vol.7
, pp. 292-306
-
-
Ma, I.1
Allan, A.L.2
-
37
-
-
84930474801
-
-
Koppaka V., Thompson D.C., Chen Y., Ellermann M., Nicolaou K.C., Juvonen R.O., et al. Aldehyde dehydrogenase inhibitors: a comprehensive review of the pharmacology, mechanism of action, substrate specificity, and clinical application, Pharmacol Rev 2012, 64:520-539.
-
(2012)
Aldehyde dehydrogenase inhibitors: a comprehensive review of the pharmacology, mechanism of action, substrate specificity, and clinical application, Pharmacol Rev
, vol.64
, pp. 520-539
-
-
Koppaka, V.1
Thompson, D.C.2
Chen, Y.3
Ellermann, M.4
Nicolaou, K.C.5
Juvonen, R.O.6
-
38
-
-
76149125786
-
Aldehyde dehydrogenase 1 A1-positive cell population is enriched in tumor-initiating cells and associated with progression of bladder cancer
-
Su Y., Qiu Q., Zhang X., Jiang Z., Leng Q., Liu Z., et al. Aldehyde dehydrogenase 1 A1-positive cell population is enriched in tumor-initiating cells and associated with progression of bladder cancer. Cancer Epidemiol Biomarkers Prev 2010, 19:327-337.
-
(2010)
Cancer Epidemiol Biomarkers Prev
, vol.19
, pp. 327-337
-
-
Su, Y.1
Qiu, Q.2
Zhang, X.3
Jiang, Z.4
Leng, Q.5
Liu, Z.6
-
39
-
-
79958716191
-
ALDH activity selectively defines an enhanced tumor-initiating cell population relative to CD133 expression in human pancreatic adenocarcinoma
-
Kim M.P., Fleming J.B., Wang H., Abbruzzese J.L., Choi W., Kopetz S., et al. ALDH activity selectively defines an enhanced tumor-initiating cell population relative to CD133 expression in human pancreatic adenocarcinoma. PLoS ONE 2011, 6:e20636.
-
(2011)
PLoS ONE
, vol.6
, pp. e20636
-
-
Kim, M.P.1
Fleming, J.B.2
Wang, H.3
Abbruzzese, J.L.4
Choi, W.5
Kopetz, S.6
-
40
-
-
77954351665
-
Possible involvement of stem-like populations with elevated ALDH1 in sarcomas for chemotherapeutic drug resistance
-
Honoki K., Fujii H., Kubo A., Kido A., Mori T., Tanaka Y., et al. Possible involvement of stem-like populations with elevated ALDH1 in sarcomas for chemotherapeutic drug resistance. Oncol Rep 2010, 24:501-505.
-
(2010)
Oncol Rep
, vol.24
, pp. 501-505
-
-
Honoki, K.1
Fujii, H.2
Kubo, A.3
Kido, A.4
Mori, T.5
Tanaka, Y.6
-
41
-
-
84860347162
-
Inhibition of aldehyde dehydrogenase (ALDH) activity reduces chemotherapy and radiation resistance of stem-like ALDHhiCD44(+) human breast cancer cells
-
Croker A.K., Allan A.L. Inhibition of aldehyde dehydrogenase (ALDH) activity reduces chemotherapy and radiation resistance of stem-like ALDHhiCD44(+) human breast cancer cells. Breast Cancer Res Treat 2012, 133:75-87.
-
(2012)
Breast Cancer Res Treat
, vol.133
, pp. 75-87
-
-
Croker, A.K.1
Allan, A.L.2
-
42
-
-
84902332685
-
Association of aldehyde dehydrogenase 1 expression and biologically aggressive features in breast cancer
-
Kang E.J., Jung H., Woo O.H., Park K.H., Woo S.U., Yang D.S., et al. Association of aldehyde dehydrogenase 1 expression and biologically aggressive features in breast cancer. Neoplasma 2014, 61:352-362.
-
(2014)
Neoplasma
, vol.61
, pp. 352-362
-
-
Kang, E.J.1
Jung, H.2
Woo, O.H.3
Park, K.H.4
Woo, S.U.5
Yang, D.S.6
-
43
-
-
73949097562
-
Overexpression of aldehyde dehydrogenase 1A1 reduces oxidation-induced toxicity in SH-SY5Y neuroblastoma cells
-
Zhang M., Shoeb M., Goswamy J., Liu P., Xiao T.L., Hogan D., et al. Overexpression of aldehyde dehydrogenase 1A1 reduces oxidation-induced toxicity in SH-SY5Y neuroblastoma cells. J Neurosci Res 2010, 88:686-694.
-
(2010)
J Neurosci Res
, vol.88
, pp. 686-694
-
-
Zhang, M.1
Shoeb, M.2
Goswamy, J.3
Liu, P.4
Xiao, T.L.5
Hogan, D.6
-
44
-
-
44949179401
-
Should supplemental antioxidant administration be avoided during chemotherapy and radiation therapy?
-
Lawenda B.D., Kelly K.M., Ladas E.J., Sagar S.M., Vickers A., Blumberg J.B. Should supplemental antioxidant administration be avoided during chemotherapy and radiation therapy?. J Natl Cancer Inst 2008, 100:773-783.
-
(2008)
J Natl Cancer Inst
, vol.100
, pp. 773-783
-
-
Lawenda, B.D.1
Kelly, K.M.2
Ladas, E.J.3
Sagar, S.M.4
Vickers, A.5
Blumberg, J.B.6
-
45
-
-
23044514578
-
Multiple drug resistance in cancer revisited: the cancer stem cell hypothesis
-
Donnenberg V.S., Donnenberg A.D. Multiple drug resistance in cancer revisited: the cancer stem cell hypothesis. J Clin Pharmacol 2005, 45:872-877.
-
(2005)
J Clin Pharmacol
, vol.45
, pp. 872-877
-
-
Donnenberg, V.S.1
Donnenberg, A.D.2
-
46
-
-
84872676923
-
Ovarian cancer stem cells
-
Zeimet A.G., Reimer D., Sopper S., Boesch M., Martowicz A., Roessler J., et al. Ovarian cancer stem cells. Neoplasma 2012, 59:747-755.
-
(2012)
Neoplasma
, vol.59
, pp. 747-755
-
-
Zeimet, A.G.1
Reimer, D.2
Sopper, S.3
Boesch, M.4
Martowicz, A.5
Roessler, J.6
-
47
-
-
34047096557
-
Cancer stem cells: models and concepts
-
Dalerba P., Cho R.W., Clarke M.F. Cancer stem cells: models and concepts. Annu Rev Med 2007, 58:267-284.
-
(2007)
Annu Rev Med
, vol.58
, pp. 267-284
-
-
Dalerba, P.1
Cho, R.W.2
Clarke, M.F.3
-
48
-
-
79955938811
-
Neoadjuvant vs adjuvant pelvic radiotherapy for locally advanced rectal cancer: Which is superior?
-
Popek S., Tsikitis V.L. Neoadjuvant vs adjuvant pelvic radiotherapy for locally advanced rectal cancer: Which is superior?. World J Gastroenterol 2011, 17:848-854.
-
(2011)
World J Gastroenterol
, vol.17
, pp. 848-854
-
-
Popek, S.1
Tsikitis, V.L.2
-
49
-
-
4344587783
-
American Society of Clinical Oncology recommendations on adjuvant chemotherapy for stage II colon cancer
-
Benson A.B., Schrag D., Somerfield M.R., Cohen A.M., Figueredo A.T., Flynn P.J., et al. American Society of Clinical Oncology recommendations on adjuvant chemotherapy for stage II colon cancer. J Clin Oncol 2004, 22:3408-3419.
-
(2004)
J Clin Oncol
, vol.22
, pp. 3408-3419
-
-
Benson, A.B.1
Schrag, D.2
Somerfield, M.R.3
Cohen, A.M.4
Figueredo, A.T.5
Flynn, P.J.6
-
50
-
-
0019277437
-
Facilitated transport of uracil and 5-fluorouracil, and permeation of orotic acid into cultured mammalian cells
-
Wohlhueter R.M., McIvor R.S., Plagemann P.G. Facilitated transport of uracil and 5-fluorouracil, and permeation of orotic acid into cultured mammalian cells. J Cell Physiol 1980, 104:309-319.
-
(1980)
J Cell Physiol
, vol.104
, pp. 309-319
-
-
Wohlhueter, R.M.1
McIvor, R.S.2
Plagemann, P.G.3
-
51
-
-
0025362969
-
Role for cytosolic folate-binding proteins in the compartmentation of endogenous tetrahydrofolates and the 5-formyl tetrahydrofolate-mediated enhancement of 5-fluoro-2'-deoxyuridine antitumor activity in vitro
-
Matherly L.H., Czajkowski C.A., Muench S.P., Psiakis J.T. Role for cytosolic folate-binding proteins in the compartmentation of endogenous tetrahydrofolates and the 5-formyl tetrahydrofolate-mediated enhancement of 5-fluoro-2'-deoxyuridine antitumor activity in vitro. Cancer Res 1990, 50:3262-3269.
-
(1990)
Cancer Res
, vol.50
, pp. 3262-3269
-
-
Matherly, L.H.1
Czajkowski, C.A.2
Muench, S.P.3
Psiakis, J.T.4
-
52
-
-
0024227210
-
Enhancement of fluorinated pyrimidine-induced cytotoxicity by leucovorin in human colorectal carcinoma cell lines
-
Park J.G., Collins J.M., Gazdar A.F., Allegra C.J., Steinberg S.M., Greene R.F., et al. Enhancement of fluorinated pyrimidine-induced cytotoxicity by leucovorin in human colorectal carcinoma cell lines. J Natl Cancer Inst 1988, 80:1560-1564.
-
(1988)
J Natl Cancer Inst
, vol.80
, pp. 1560-1564
-
-
Park, J.G.1
Collins, J.M.2
Gazdar, A.F.3
Allegra, C.J.4
Steinberg, S.M.5
Greene, R.F.6
-
53
-
-
0024267939
-
In vivo potentiation of 5-fluorouracil by leucovorin in murine colon carcinoma
-
Nadal J.C., Van Groeningen C.J., Pinedo H.M., Peters G.J. In vivo potentiation of 5-fluorouracil by leucovorin in murine colon carcinoma. Biomed Pharmacother 1988, 42:387-393.
-
(1988)
Biomed Pharmacother
, vol.42
, pp. 387-393
-
-
Nadal, J.C.1
Van Groeningen, C.J.2
Pinedo, H.M.3
Peters, G.J.4
-
54
-
-
0024413891
-
Selective expansion of 5,10-methylenetetrahydrofolate pools and modulation of 5-fluorouracil antitumor activity by leucovorin in vivo
-
Wright J.E., Dreyfuss A., el-Magharbel I., Trites D., Jones S.M., Holden S.A., et al. Selective expansion of 5,10-methylenetetrahydrofolate pools and modulation of 5-fluorouracil antitumor activity by leucovorin in vivo. Cancer Res 1989, 49:2592-2596.
-
(1989)
Cancer Res
, vol.49
, pp. 2592-2596
-
-
Wright, J.E.1
Dreyfuss, A.2
el-Magharbel, I.3
Trites, D.4
Jones, S.M.5
Holden, S.A.6
-
55
-
-
0032127244
-
Design of a novel oral fluoropyrimidine carbamate, capecitabine, which generates 5-fluorouracil selectively in tumours by enzymes concentrated in human liver and cancer tissue
-
Miwa M., Ura M., Nishida M., Sawada N., Ishikawa T., Mori K., et al. Design of a novel oral fluoropyrimidine carbamate, capecitabine, which generates 5-fluorouracil selectively in tumours by enzymes concentrated in human liver and cancer tissue. Eur J Cancer 1998, 34:1274-1281.
-
(1998)
Eur J Cancer
, vol.34
, pp. 1274-1281
-
-
Miwa, M.1
Ura, M.2
Nishida, M.3
Sawada, N.4
Ishikawa, T.5
Mori, K.6
-
56
-
-
0037089505
-
Uridine phosphorylase (-/-) murine embryonic stem cells clarify the key role of this enzyme in the regulation of the pyrimidine salvage pathway and in the activation of fluoropyrimidines
-
Cao D., Russell R.L., Zhang D., Leffert J.J., Pizzorno G. Uridine phosphorylase (-/-) murine embryonic stem cells clarify the key role of this enzyme in the regulation of the pyrimidine salvage pathway and in the activation of fluoropyrimidines. Cancer Res 2002, 62:2313-2317.
-
(2002)
Cancer Res
, vol.62
, pp. 2313-2317
-
-
Cao, D.1
Russell, R.L.2
Zhang, D.3
Leffert, J.J.4
Pizzorno, G.5
-
57
-
-
0038387494
-
5-fluorouracil: mechanisms of action and clinical strategies
-
Longley D.B., Harkin D.P., Johnston P.G. 5-fluorouracil: mechanisms of action and clinical strategies. Nat Rev Cancer 2003, 3:330-338.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 330-338
-
-
Longley, D.B.1
Harkin, D.P.2
Johnston, P.G.3
-
58
-
-
0022340594
-
Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I
-
Hsiang Y.H., Hertzberg R., Hecht S., Liu L.F. Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I. J Biol Chem 1985, 260:14873-14878.
-
(1985)
J Biol Chem
, vol.260
, pp. 14873-14878
-
-
Hsiang, Y.H.1
Hertzberg, R.2
Hecht, S.3
Liu, L.F.4
-
59
-
-
0031782847
-
Sequence- and region-specificity of oxaliplatin adducts in naked and cellular DNA
-
Woynarowski J.M., Chapman W.G., Napier C., Herzig M.C., Juniewicz P. Sequence- and region-specificity of oxaliplatin adducts in naked and cellular DNA. Mol Pharmacol 1998, 54:770-777.
-
(1998)
Mol Pharmacol
, vol.54
, pp. 770-777
-
-
Woynarowski, J.M.1
Chapman, W.G.2
Napier, C.3
Herzig, M.C.4
Juniewicz, P.5
-
60
-
-
67650759744
-
Evolving treatment of advanced colon cancer
-
Segal N.H., Saltz L.B. Evolving treatment of advanced colon cancer. Annu Rev Med 2009, 60:207-219.
-
(2009)
Annu Rev Med
, vol.60
, pp. 207-219
-
-
Segal, N.H.1
Saltz, L.B.2
-
61
-
-
0020524876
-
Characterization of the adducts produced in DNA by cis-diamminedichloroplatinum(II) and cis-dichloro(ethylenediamine)platinum(II)
-
Eastman A. Characterization of the adducts produced in DNA by cis-diamminedichloroplatinum(II) and cis-dichloro(ethylenediamine)platinum(II). Biochemistry 1983, 22:3927-3933.
-
(1983)
Biochemistry
, vol.22
, pp. 3927-3933
-
-
Eastman, A.1
-
62
-
-
10644245994
-
Recognition and processing of cisplatin- and oxaliplatin-DNA adducts
-
Chaney S.G., Campbell S.L., Bassett E., Wu Y. Recognition and processing of cisplatin- and oxaliplatin-DNA adducts. Crit Rev Oncol Hematol 2005, 53:3-11.
-
(2005)
Crit Rev Oncol Hematol
, vol.53
, pp. 3-11
-
-
Chaney, S.G.1
Campbell, S.L.2
Bassett, E.3
Wu, Y.4
-
63
-
-
0037059778
-
MutS preferentially recognizes cisplatin- over oxaliplatin-modified DNA
-
Zdraveski Z.Z., Mello J.A., Farinelli C.K., Essigmann J.M., Marinus M.G. MutS preferentially recognizes cisplatin- over oxaliplatin-modified DNA. J Biol Chem 2002, 277:1255-1260.
-
(2002)
J Biol Chem
, vol.277
, pp. 1255-1260
-
-
Zdraveski, Z.Z.1
Mello, J.A.2
Farinelli, C.K.3
Essigmann, J.M.4
Marinus, M.G.5
-
64
-
-
18244379333
-
Cellular processing of platinum anticancer drugs
-
Wang D., Lippard S.J. Cellular processing of platinum anticancer drugs. Nat Rev Drug Discov 2005, 4:307-320.
-
(2005)
Nat Rev Drug Discov
, vol.4
, pp. 307-320
-
-
Wang, D.1
Lippard, S.J.2
-
66
-
-
0023628351
-
The formation, isolation and characterization of DNA adducts produced by anticancer platinum complexes
-
Eastman A. The formation, isolation and characterization of DNA adducts produced by anticancer platinum complexes. Pharmacol Ther 1987, 34:155-166.
-
(1987)
Pharmacol Ther
, vol.34
, pp. 155-166
-
-
Eastman, A.1
-
67
-
-
0345256652
-
Cisplatin: mode of cytotoxic action and molecular basis of resistance
-
Siddik Z.H. Cisplatin: mode of cytotoxic action and molecular basis of resistance. Oncogene 2003, 22:7265-7279.
-
(2003)
Oncogene
, vol.22
, pp. 7265-7279
-
-
Siddik, Z.H.1
-
68
-
-
0031974420
-
Cross-resistance to methotrexate and metals in human cisplatin-resistant cell lines results from a pleiotropic defect in accumulation of these compounds associated with reduced plasma membrane binding proteins
-
Shen D., Pastan I., Gottesman M.M. Cross-resistance to methotrexate and metals in human cisplatin-resistant cell lines results from a pleiotropic defect in accumulation of these compounds associated with reduced plasma membrane binding proteins. Cancer Res 1998, 58:268-275.
-
(1998)
Cancer Res
, vol.58
, pp. 268-275
-
-
Shen, D.1
Pastan, I.2
Gottesman, M.M.3
-
69
-
-
0034036384
-
Preclinical perspectives on platinum resistance
-
[discussion 37-38]
-
Kelland L.R. Preclinical perspectives on platinum resistance. Drugs 2000, 59(Suppl. 4):1-8. [discussion 37-38].
-
(2000)
Drugs
, vol.59
, pp. 1-8
-
-
Kelland, L.R.1
-
70
-
-
0033621774
-
Decreased accumulation of [14C]carboplatin in human cisplatin-resistant cells results from reduced energy-dependent uptake
-
Shen D.W., Goldenberg S., Pastan I., Gottesman M.M. Decreased accumulation of [14C]carboplatin in human cisplatin-resistant cells results from reduced energy-dependent uptake. J Cell Physiol 2000, 183:108-116.
-
(2000)
J Cell Physiol
, vol.183
, pp. 108-116
-
-
Shen, D.W.1
Goldenberg, S.2
Pastan, I.3
Gottesman, M.M.4
-
71
-
-
0036176510
-
Mechanisms of cancer drug resistance
-
Gottesman M.M. Mechanisms of cancer drug resistance. Annu Rev Med 2002, 53:615-627.
-
(2002)
Annu Rev Med
, vol.53
, pp. 615-627
-
-
Gottesman, M.M.1
-
72
-
-
0036364467
-
Multidrug resistance in cancer: role of ATP-dependent transporters
-
Gottesman M.M., Fojo T., Bates S.E. Multidrug resistance in cancer: role of ATP-dependent transporters. Nat Rev Cancer 2002, 2:48-58.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 48-58
-
-
Gottesman, M.M.1
Fojo, T.2
Bates, S.E.3
-
73
-
-
0035079539
-
Ceramide glycosylation potentiates cellular multidrug resistance
-
Liu Y.Y., Han T.Y., Giuliano A.E., Cabot M.C. Ceramide glycosylation potentiates cellular multidrug resistance. FASEB J 2001, 15:719-730.
-
(2001)
FASEB J
, vol.15
, pp. 719-730
-
-
Liu, Y.Y.1
Han, T.Y.2
Giuliano, A.E.3
Cabot, M.C.4
-
74
-
-
0035038919
-
The orphan nuclear receptor SXR coordinately regulates drug metabolism and efflux
-
Synold T.W., Dussault I., Forman B.M. The orphan nuclear receptor SXR coordinately regulates drug metabolism and efflux. Nat Med 2001, 7:584-590.
-
(2001)
Nat Med
, vol.7
, pp. 584-590
-
-
Synold, T.W.1
Dussault, I.2
Forman, B.M.3
-
75
-
-
0034917716
-
The human ATP-binding cassette (ABC) transporter superfamily
-
Dean M., Rzhetsky A., Allikmets R. The human ATP-binding cassette (ABC) transporter superfamily. Genome Res 2001, 11:1156-1166.
-
(2001)
Genome Res
, vol.11
, pp. 1156-1166
-
-
Dean, M.1
Rzhetsky, A.2
Allikmets, R.3
-
76
-
-
14644444547
-
ABC transporters in the balance: is there a role in multidrug resistance?
-
Polgar O., Bates S.E. ABC transporters in the balance: is there a role in multidrug resistance?. Biochem Soc Trans 2005, 33:241-245.
-
(2005)
Biochem Soc Trans
, vol.33
, pp. 241-245
-
-
Polgar, O.1
Bates, S.E.2
-
77
-
-
34249679271
-
ABC transporters and drug resistance in leukemia: was P-gp nothing but the first head of the Hydra?
-
Steinbach D., Legrand O. ABC transporters and drug resistance in leukemia: was P-gp nothing but the first head of the Hydra?. Leukemia 2007, 21:1172-1176.
-
(2007)
Leukemia
, vol.21
, pp. 1172-1176
-
-
Steinbach, D.1
Legrand, O.2
-
78
-
-
0025007511
-
Pharmacology of drugs that alter multidrug resistance in cancer
-
Ford J.M., Hait W.N. Pharmacology of drugs that alter multidrug resistance in cancer. Pharmacol Rev 1990, 42:155-199.
-
(1990)
Pharmacol Rev
, vol.42
, pp. 155-199
-
-
Ford, J.M.1
Hait, W.N.2
-
79
-
-
2542491777
-
The role of ABC transporters in drug resistance, metabolism and toxicity
-
Glavinas H., Krajcsi P., Cserepes J., Sarkadi B. The role of ABC transporters in drug resistance, metabolism and toxicity. Curr Drug Deliv 2004, 1:27-42.
-
(2004)
Curr Drug Deliv
, vol.1
, pp. 27-42
-
-
Glavinas, H.1
Krajcsi, P.2
Cserepes, J.3
Sarkadi, B.4
-
80
-
-
84900433657
-
Folate receptor-targeted liposomes enhanced the antitumor potency of imatinib through the combination of active targeting and molecular targeting
-
Ye P., Zhang W., Yang T., Lu Y., Lu M., Gai Y., et al. Folate receptor-targeted liposomes enhanced the antitumor potency of imatinib through the combination of active targeting and molecular targeting. Int J Nanomedicine 2014, 9:2167-2178.
-
(2014)
Int J Nanomedicine
, vol.9
, pp. 2167-2178
-
-
Ye, P.1
Zhang, W.2
Yang, T.3
Lu, Y.4
Lu, M.5
Gai, Y.6
-
81
-
-
84902489807
-
DrugComboRanker: drug combination discovery based on target network analysis
-
Huang L., Li F., Sheng J., Xia X., Ma J., Zhan M., et al. DrugComboRanker: drug combination discovery based on target network analysis. Bioinformatics 2014, 30:i228-i236.
-
(2014)
Bioinformatics
, vol.30
, pp. i228-i236
-
-
Huang, L.1
Li, F.2
Sheng, J.3
Xia, X.4
Ma, J.5
Zhan, M.6
-
83
-
-
34848866647
-
Colon cancer stem cells dictate tumor growth and resist cell death by production of interleukin-4
-
Todaro M., Alea M.P., Di Stefano A.B., Cammareri P., Vermeulen L., Iovino F., et al. Colon cancer stem cells dictate tumor growth and resist cell death by production of interleukin-4. Cell Stem Cell 2007, 1:389-402.
-
(2007)
Cell Stem Cell
, vol.1
, pp. 389-402
-
-
Todaro, M.1
Alea, M.P.2
Di Stefano, A.B.3
Cammareri, P.4
Vermeulen, L.5
Iovino, F.6
-
84
-
-
84896778994
-
In vivo 5FU-exposed human medullary thyroid carcinoma cells contain a chemoresistant CD133+ tumor-initiating cell subset
-
Kucerova L., Feketeova L., Kozovska Z., Poturnajova M., Matuskova M., Nencka R., et al. In vivo 5FU-exposed human medullary thyroid carcinoma cells contain a chemoresistant CD133+ tumor-initiating cell subset. Thyroid 2014, 24:520-532.
-
(2014)
Thyroid
, vol.24
, pp. 520-532
-
-
Kucerova, L.1
Feketeova, L.2
Kozovska, Z.3
Poturnajova, M.4
Matuskova, M.5
Nencka, R.6
|