-
1
-
-
79951798738
-
Rac1 targeting suppresses human non-small cell lung adenocarcinoma cancer stem cell activity
-
Akunuru S., Palumbo J., Zhai Q.J., Zheng Y. Rac1 targeting suppresses human non-small cell lung adenocarcinoma cancer stem cell activity. PLoS ONE 2011, 6:e16951.
-
(2011)
PLoS ONE
, vol.6
, pp. e16951
-
-
Akunuru, S.1
Palumbo, J.2
Zhai, Q.J.3
Zheng, Y.4
-
2
-
-
33845317573
-
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
-
Bao S., Wu Q., McLendon R.E., Hao Y., Shi Q., Hjelmeland A.B., Dewhirst M.W., Bigner D.D., Rich J.N. Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature 2006, 444:756-760.
-
(2006)
Nature
, vol.444
, pp. 756-760
-
-
Bao, S.1
Wu, Q.2
McLendon, R.E.3
Hao, Y.4
Shi, Q.5
Hjelmeland, A.B.6
Dewhirst, M.W.7
Bigner, D.D.8
Rich, J.N.9
-
3
-
-
84883656941
-
Mesenchymal differentiation mediated by NF-κB promotes radiation resistance in glioblastoma
-
Bhat K.P., Balasubramaniyan V., Vaillant B., Ezhilarasan R., Hummelink K., Hollingsworth F., Wani K., Heathcock L., James J.D., Goodman L.D., et al. Mesenchymal differentiation mediated by NF-κB promotes radiation resistance in glioblastoma. Cancer Cell 2013, 24:331-346.
-
(2013)
Cancer Cell
, vol.24
, pp. 331-346
-
-
Bhat, K.P.1
Balasubramaniyan, V.2
Vaillant, B.3
Ezhilarasan, R.4
Hummelink, K.5
Hollingsworth, F.6
Wani, K.7
Heathcock, L.8
James, J.D.9
Goodman, L.D.10
-
4
-
-
79952400966
-
A role for class 3 semaphorins in prostate cancer
-
Blanc V., Nariculam J., Munson P., Freeman A., Klocker H., Masters J., Williamson M. A role for class 3 semaphorins in prostate cancer. Prostate 2011, 71:649-658.
-
(2011)
Prostate
, vol.71
, pp. 649-658
-
-
Blanc, V.1
Nariculam, J.2
Munson, P.3
Freeman, A.4
Klocker, H.5
Masters, J.6
Williamson, M.7
-
5
-
-
60849117508
-
PTEN/PI3K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells
-
Bleau A.M., Hambardzumyan D., Ozawa T., Fomchenko E.I., Huse J.T., Brennan C.W., Holland E.C. PTEN/PI3K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells. Cell Stem Cell 2009, 4:226-235.
-
(2009)
Cell Stem Cell
, vol.4
, pp. 226-235
-
-
Bleau, A.M.1
Hambardzumyan, D.2
Ozawa, T.3
Fomchenko, E.I.4
Huse, J.T.5
Brennan, C.W.6
Holland, E.C.7
-
6
-
-
79951844223
-
NFKBIA deletion in glioblastomas
-
Bredel M., Scholtens D.M., Yadav A.K., Alvarez A.A., Renfrow J.J., Chandler J.P., Yu I.L., Carro M.S., Dai F., Tagge M.J., et al. NFKBIA deletion in glioblastomas. N.Engl. J. Med. 2011, 364:627-637.
-
(2011)
N.Engl. J. Med.
, vol.364
, pp. 627-637
-
-
Bredel, M.1
Scholtens, D.M.2
Yadav, A.K.3
Alvarez, A.A.4
Renfrow, J.J.5
Chandler, J.P.6
Yu, I.L.7
Carro, M.S.8
Dai, F.9
Tagge, M.J.10
-
7
-
-
84885074034
-
The somatic genomic landscape of glioblastoma
-
Brennan C.W., Verhaak R.G., McKenna A., Campos B., Noushmehr H., Salama S.R., Zheng S., Chakravarty D., Sanborn J.Z., Berman S.H., et al. The somatic genomic landscape of glioblastoma. Cell 2013, 155:462-477. TCGA Research Network.
-
(2013)
Cell
, vol.155
, pp. 462-477
-
-
Brennan, C.W.1
Verhaak, R.G.2
McKenna, A.3
Campos, B.4
Noushmehr, H.5
Salama, S.R.6
Zheng, S.7
Chakravarty, D.8
Sanborn, J.Z.9
Berman, S.H.10
-
8
-
-
33846029123
-
A perivascular niche for brain tumor stem cells
-
Calabrese C., Poppleton H., Kocak M., Hogg T.L., Fuller C., Hamner B., Oh E.Y., Gaber M.W., Finklestein D., Allen M., et al. A perivascular niche for brain tumor stem cells. Cancer Cell 2007, 11:69-82.
-
(2007)
Cancer Cell
, vol.11
, pp. 69-82
-
-
Calabrese, C.1
Poppleton, H.2
Kocak, M.3
Hogg, T.L.4
Fuller, C.5
Hamner, B.6
Oh, E.Y.7
Gaber, M.W.8
Finklestein, D.9
Allen, M.10
-
9
-
-
69449097679
-
Semaphorin signaling in cancer cells and in cells of the tumor microenvironment-two sides of a coin
-
Capparuccia L., Tamagnone L. Semaphorin signaling in cancer cells and in cells of the tumor microenvironment-two sides of a coin. J.Cell Sci. 2009, 122:1723-1736.
-
(2009)
J.Cell Sci.
, vol.122
, pp. 1723-1736
-
-
Capparuccia, L.1
Tamagnone, L.2
-
10
-
-
28344456263
-
Roles of the Rac1 and Rac3 GTPases in human tumor cell invasion
-
Chan A.Y., Coniglio S.J., Chuang Y.Y., Michaelson D., Knaus U.G., Philips M.R., Symons M. Roles of the Rac1 and Rac3 GTPases in human tumor cell invasion. Oncogene 2005, 24:7821-7829.
-
(2005)
Oncogene
, vol.24
, pp. 7821-7829
-
-
Chan, A.Y.1
Coniglio, S.J.2
Chuang, Y.Y.3
Michaelson, D.4
Knaus, U.G.5
Philips, M.R.6
Symons, M.7
-
11
-
-
84865203983
-
A restricted cell population propagates glioblastoma growth after chemotherapy
-
Chen J., Li Y., Yu T.S., McKay R.M., Burns D.K., Kernie S.G., Parada L.F. A restricted cell population propagates glioblastoma growth after chemotherapy. Nature 2012, 488:522-526.
-
(2012)
Nature
, vol.488
, pp. 522-526
-
-
Chen, J.1
Li, Y.2
Yu, T.S.3
McKay, R.M.4
Burns, D.K.5
Kernie, S.G.6
Parada, L.F.7
-
12
-
-
84875755046
-
Glioblastoma stem cells generate vascular pericytes to support vessel function and tumor growth
-
Cheng L., Huang Z., Zhou W., Wu Q., Donnola S., Liu J.K., Fang X., Sloan A.E., Mao Y., Lathia J.D., et al. Glioblastoma stem cells generate vascular pericytes to support vessel function and tumor growth. Cell 2013, 153:139-152.
-
(2013)
Cell
, vol.153
, pp. 139-152
-
-
Cheng, L.1
Huang, Z.2
Zhou, W.3
Wu, Q.4
Donnola, S.5
Liu, J.K.6
Fang, X.7
Sloan, A.E.8
Mao, Y.9
Lathia, J.D.10
-
13
-
-
33745198882
-
Chemotherapy resistance of glioblastoma stem cells
-
Eramo A., Ricci-Vitiani L., Zeuner A., Pallini R., Lotti F., Sette G., Pilozzi E., Larocca L.M., Peschle C., De Maria R. Chemotherapy resistance of glioblastoma stem cells. Cell Death Differ. 2006, 13:1238-1241.
-
(2006)
Cell Death Differ.
, vol.13
, pp. 1238-1241
-
-
Eramo, A.1
Ricci-Vitiani, L.2
Zeuner, A.3
Pallini, R.4
Lotti, F.5
Sette, G.6
Pilozzi, E.7
Larocca, L.M.8
Peschle, C.9
De Maria, R.10
-
14
-
-
77449159177
-
The cleavage of semaphorin 3C induced by ADAMTS1 promotes cell migration
-
Esselens C., Malapeira J., Colomé N., Casal C., Rodríguez-Manzaneque J.C., Canals F., Arribas J. The cleavage of semaphorin 3C induced by ADAMTS1 promotes cell migration. J.Biol. Chem. 2010, 285:2463-2473.
-
(2010)
J.Biol. Chem.
, vol.285
, pp. 2463-2473
-
-
Esselens, C.1
Malapeira, J.2
Colomé, N.3
Casal, C.4
Rodríguez-Manzaneque, J.C.5
Canals, F.6
Arribas, J.7
-
15
-
-
34047269793
-
Activation of tumor-specific splice variant Rac1b by dishevelled promotes canonical Wnt signaling and decreased adhesion of colorectal cancer cells
-
Esufali S., Charames G.S., Pethe V.V., Buongiorno P., Bapat B. Activation of tumor-specific splice variant Rac1b by dishevelled promotes canonical Wnt signaling and decreased adhesion of colorectal cancer cells. Cancer Res. 2007, 67:2469-2479.
-
(2007)
Cancer Res.
, vol.67
, pp. 2469-2479
-
-
Esufali, S.1
Charames, G.S.2
Pethe, V.V.3
Buongiorno, P.4
Bapat, B.5
-
16
-
-
84055191095
-
Activation of Rac1 by Src-dependent phosphorylation of Dock180(Y1811) mediates PDGFRα-stimulated glioma tumorigenesis in mice and humans
-
Feng H., Hu B., Liu K.W., Li Y., Lu X., Cheng T., Yiin J.J., Lu S., Keezer S., Fenton T., et al. Activation of Rac1 by Src-dependent phosphorylation of Dock180(Y1811) mediates PDGFRα-stimulated glioma tumorigenesis in mice and humans. J.Clin. Invest. 2011, 121:4670-4684.
-
(2011)
J.Clin. Invest.
, vol.121
, pp. 4670-4684
-
-
Feng, H.1
Hu, B.2
Liu, K.W.3
Li, Y.4
Lu, X.5
Cheng, T.6
Yiin, J.J.7
Lu, S.8
Keezer, S.9
Fenton, T.10
-
18
-
-
0036336723
-
Correlation of MDR-1, nm23-H1 and H Sema E gene expression with histopathological findings and clinical outcome in ovarian and breast cancer patients
-
Galani E., Sgouros J., Petropoulou C., Janinis J., Aravantinos G., Dionysiou-Asteriou D., Skarlos D., Gonos E. Correlation of MDR-1, nm23-H1 and H Sema E gene expression with histopathological findings and clinical outcome in ovarian and breast cancer patients. Anticancer Res. 2002, 22:2275-2280.
-
(2002)
Anticancer Res.
, vol.22
, pp. 2275-2280
-
-
Galani, E.1
Sgouros, J.2
Petropoulou, C.3
Janinis, J.4
Aravantinos, G.5
Dionysiou-Asteriou, D.6
Skarlos, D.7
Gonos, E.8
-
19
-
-
84891785971
-
Dose-dense temozolomide for newly diagnosed glioblastoma: a randomized phase III clinical trial
-
Gilbert M.R., Wang M., Aldape K.D., Stupp R., Hegi M.E., Jaeckle K.A., Armstrong T.S., Wefel J.S., Won M., Blumenthal D.T., et al. Dose-dense temozolomide for newly diagnosed glioblastoma: a randomized phase III clinical trial. J.Clin. Oncol. 2013, 31:4085-4091.
-
(2013)
J.Clin. Oncol.
, vol.31
, pp. 4085-4091
-
-
Gilbert, M.R.1
Wang, M.2
Aldape, K.D.3
Stupp, R.4
Hegi, M.E.5
Jaeckle, K.A.6
Armstrong, T.S.7
Wefel, J.S.8
Won, M.9
Blumenthal, D.T.10
-
20
-
-
34648821254
-
Making a tumour's bed: glioblastoma stem cells and the vascular niche
-
Gilbertson R.J., Rich J.N. Making a tumour's bed: glioblastoma stem cells and the vascular niche. Nat. Rev. Cancer 2007, 7:733-736.
-
(2007)
Nat. Rev. Cancer
, vol.7
, pp. 733-736
-
-
Gilbertson, R.J.1
Rich, J.N.2
-
21
-
-
4344594556
-
PlexinD1 and semaphorin signaling are required in endothelial cells for cardiovascular development
-
Gitler A.D., Lu M.M., Epstein J.A. PlexinD1 and semaphorin signaling are required in endothelial cells for cardiovascular development. Dev. Cell 2004, 7:107-116.
-
(2004)
Dev. Cell
, vol.7
, pp. 107-116
-
-
Gitler, A.D.1
Lu, M.M.2
Epstein, J.A.3
-
22
-
-
0142084736
-
Hematopoietic cell regulation by Rac1 and Rac2 guanosine triphosphatases
-
Gu Y., Filippi M.D., Cancelas J.A., Siefring J.E., Williams E.P., Jasti A.C., Harris C.E., Lee A.W., Prabhakar R., Atkinson S.J., et al. Hematopoietic cell regulation by Rac1 and Rac2 guanosine triphosphatases. Science 2003, 302:445-449.
-
(2003)
Science
, vol.302
, pp. 445-449
-
-
Gu, Y.1
Filippi, M.D.2
Cancelas, J.A.3
Siefring, J.E.4
Williams, E.P.5
Jasti, A.C.6
Harris, C.E.7
Lee, A.W.8
Prabhakar, R.9
Atkinson, S.J.10
-
23
-
-
79953757100
-
Nonreceptor tyrosine kinase BMX maintains self-renewal and tumorigenic potential of glioblastoma stem cells by activating STAT3
-
Guryanova O.A., Wu Q., Cheng L., Lathia J.D., Huang Z., Yang J., MacSwords J., Eyler C.E., McLendon R.E., Heddleston J.M., et al. Nonreceptor tyrosine kinase BMX maintains self-renewal and tumorigenic potential of glioblastoma stem cells by activating STAT3. Cancer Cell 2011, 19:498-511.
-
(2011)
Cancer Cell
, vol.19
, pp. 498-511
-
-
Guryanova, O.A.1
Wu, Q.2
Cheng, L.3
Lathia, J.D.4
Huang, Z.5
Yang, J.6
MacSwords, J.7
Eyler, C.E.8
McLendon, R.E.9
Heddleston, J.M.10
-
24
-
-
84860356630
-
Autocrine VEGF-VEGFR2-Neuropilin-1 signaling promotes glioma stem-like cell viability and tumor growth
-
Hamerlik P., Lathia J.D., Rasmussen R., Wu Q., Bartkova J., Lee M., Moudry P., Bartek J., Fischer W., Lukas J., et al. Autocrine VEGF-VEGFR2-Neuropilin-1 signaling promotes glioma stem-like cell viability and tumor growth. J.Exp. Med. 2012, 209:507-520.
-
(2012)
J.Exp. Med.
, vol.209
, pp. 507-520
-
-
Hamerlik, P.1
Lathia, J.D.2
Rasmussen, R.3
Wu, Q.4
Bartkova, J.5
Lee, M.6
Moudry, P.7
Bartek, J.8
Fischer, W.9
Lukas, J.10
-
25
-
-
50149083752
-
Mammalian Rho GTPases: new insights into their functions from invivo studies
-
Heasman S.J., Ridley A.J. Mammalian Rho GTPases: new insights into their functions from invivo studies. Nat. Rev. Mol. Cell Biol. 2008, 9:690-701.
-
(2008)
Nat. Rev. Mol. Cell Biol.
, vol.9
, pp. 690-701
-
-
Heasman, S.J.1
Ridley, A.J.2
-
26
-
-
34447345999
-
Increased class 3 semaphorin expression modulates the invasive and adhesive properties of prostate cancer cells
-
Herman J.G., Meadows G.G. Increased class 3 semaphorin expression modulates the invasive and adhesive properties of prostate cancer cells. Int. J. Oncol. 2007, 30:1231-1238.
-
(2007)
Int. J. Oncol.
, vol.30
, pp. 1231-1238
-
-
Herman, J.G.1
Meadows, G.G.2
-
27
-
-
84864258996
-
A landscape of driver mutations in melanoma
-
Hodis E., Watson I.R., Kryukov G.V., Arold S.T., Imielinski M., Theurillat J.P., Nickerson E., Auclair D., Li L., Place C., et al. A landscape of driver mutations in melanoma. Cell 2012, 150:251-263.
-
(2012)
Cell
, vol.150
, pp. 251-263
-
-
Hodis, E.1
Watson, I.R.2
Kryukov, G.V.3
Arold, S.T.4
Imielinski, M.5
Theurillat, J.P.6
Nickerson, E.7
Auclair, D.8
Li, L.9
Place, C.10
-
28
-
-
84867848485
-
Plexin structures are coming: opportunities for multilevel investigations of semaphorin guidance receptors, their cell signaling mechanisms, and functions
-
Hota P.K., Buck M. Plexin structures are coming: opportunities for multilevel investigations of semaphorin guidance receptors, their cell signaling mechanisms, and functions. Cell. Mol. Life Sci. 2012, 69:3765-3805.
-
(2012)
Cell. Mol. Life Sci.
, vol.69
, pp. 3765-3805
-
-
Hota, P.K.1
Buck, M.2
-
29
-
-
79551600613
-
Deubiquitylase HAUSP stabilizes REST and promotes maintenance of neural progenitor cells
-
Huang Z., Wu Q., Guryanova O.A., Cheng L., Shou W., Rich J.N., Bao S. Deubiquitylase HAUSP stabilizes REST and promotes maintenance of neural progenitor cells. Nat. Cell Biol. 2011, 13:142-152.
-
(2011)
Nat. Cell Biol.
, vol.13
, pp. 142-152
-
-
Huang, Z.1
Wu, Q.2
Guryanova, O.A.3
Cheng, L.4
Shou, W.5
Rich, J.N.6
Bao, S.7
-
30
-
-
70350497349
-
Autocrine TGF-beta signaling maintains tumorigenicity of glioma-initiating cells through Sry-related HMG-box factors
-
Ikushima H., Todo T., Ino Y., Takahashi M., Miyazawa K., Miyazono K. Autocrine TGF-beta signaling maintains tumorigenicity of glioma-initiating cells through Sry-related HMG-box factors. Cell Stem Cell 2009, 5:504-514.
-
(2009)
Cell Stem Cell
, vol.5
, pp. 504-514
-
-
Ikushima, H.1
Todo, T.2
Ino, Y.3
Takahashi, M.4
Miyazawa, K.5
Miyazono, K.6
-
31
-
-
84864863728
-
MET signaling regulates glioblastoma stem cells
-
Joo K.M., Jin J., Kim E., Ho Kim K., Kim Y., Gu Kang B., Kang Y.J., Lathia J.D., Cheong K.H., Song P.H., et al. MET signaling regulates glioblastoma stem cells. Cancer Res. 2012, 72:3828-3838.
-
(2012)
Cancer Res.
, vol.72
, pp. 3828-3838
-
-
Joo, K.M.1
Jin, J.2
Kim, E.3
Ho Kim, K.4
Kim, Y.5
Gu Kang, B.6
Kang, Y.J.7
Lathia, J.D.8
Cheong, K.H.9
Song, P.H.10
-
32
-
-
0032860424
-
Regulation of the cytoskeleton and cell adhesion by the Rho family GTPases in mammalian cells
-
Kaibuchi K., Kuroda S., Amano M. Regulation of the cytoskeleton and cell adhesion by the Rho family GTPases in mammalian cells. Annu. Rev. Biochem. 1999, 68:459-486.
-
(1999)
Annu. Rev. Biochem.
, vol.68
, pp. 459-486
-
-
Kaibuchi, K.1
Kuroda, S.2
Amano, M.3
-
33
-
-
69549138482
-
GATA6 mutations cause human cardiac outflow tract defects by disrupting semaphorin-plexin signaling
-
Kodo K., Nishizawa T., Furutani M., Arai S., Yamamura E., Joo K., Takahashi T., Matsuoka R., Yamagishi H. GATA6 mutations cause human cardiac outflow tract defects by disrupting semaphorin-plexin signaling. Proc. Natl. Acad. Sci. USA 2009, 106:13933-13938.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 13933-13938
-
-
Kodo, K.1
Nishizawa, T.2
Furutani, M.3
Arai, S.4
Yamamura, E.5
Joo, K.6
Takahashi, T.7
Matsuoka, R.8
Yamagishi, H.9
-
34
-
-
84865684161
-
Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma
-
Krauthammer M., Kong Y., Ha B.H., Evans P., Bacchiocchi A., McCusker J.P., Cheng E., Davis M.J., Goh G., Choi M., et al. Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma. Nat. Genet. 2012, 44:1006-1014.
-
(2012)
Nat. Genet.
, vol.44
, pp. 1006-1014
-
-
Krauthammer, M.1
Kong, Y.2
Ha, B.H.3
Evans, P.4
Bacchiocchi, A.5
McCusker, J.P.6
Cheng, E.7
Davis, M.J.8
Goh, G.9
Choi, M.10
-
35
-
-
84875998274
-
Markers of response for the antiangiogenic agent bevacizumab
-
Lambrechts D., Lenz H.J., de Haas S., Carmeliet P., Scherer S.J. Markers of response for the antiangiogenic agent bevacizumab. J.Clin. Oncol. 2013, 31:1219-1230.
-
(2013)
J.Clin. Oncol.
, vol.31
, pp. 1219-1230
-
-
Lambrechts, D.1
Lenz, H.J.2
de Haas, S.3
Carmeliet, P.4
Scherer, S.J.5
-
36
-
-
84892927259
-
The role of semaphorins and their receptors in gliomas
-
Law J.W.S., Lee A.Y.W. The role of semaphorins and their receptors in gliomas. J.Signal Transduct. 2012, 2012:902854.
-
(2012)
J.Signal Transduct.
, vol.2012
, pp. 902854
-
-
Law, J.W.S.1
Lee, A.Y.W.2
-
37
-
-
84863754907
-
VEGF inhibits tumor cell invasion and mesenchymal transition through a MET/VEGFR2 complex
-
Lu K.V., Chang J.P., Parachoniak C.A., Pandika M.M., Aghi M.K., Meyronet D., Isachenko N., Fouse S.D., Phillips J.J., Cheresh D.A., et al. VEGF inhibits tumor cell invasion and mesenchymal transition through a MET/VEGFR2 complex. Cancer Cell 2012, 22:21-35.
-
(2012)
Cancer Cell
, vol.22
, pp. 21-35
-
-
Lu, K.V.1
Chang, J.P.2
Parachoniak, C.A.3
Pandika, M.M.4
Aghi, M.K.5
Meyronet, D.6
Isachenko, N.7
Fouse, S.D.8
Phillips, J.J.9
Cheresh, D.A.10
-
38
-
-
0345466647
-
Identification of semaphorin E gene expression in metastatic human lung adenocarcinoma cells by mRNA differential display
-
Martín-Satué M., Blanco J. Identification of semaphorin E gene expression in metastatic human lung adenocarcinoma cells by mRNA differential display. J.Surg. Oncol. 1999, 72:18-23.
-
(1999)
J.Surg. Oncol.
, vol.72
, pp. 18-23
-
-
Martín-Satué, M.1
Blanco, J.2
-
39
-
-
84868209365
-
Semaphorin 3C is involved in the progression of gastric cancer
-
Miyato H., Tsuno N.H., Kitayama J. Semaphorin 3C is involved in the progression of gastric cancer. Cancer Sci. 2012, 103:1961-1966.
-
(2012)
Cancer Sci.
, vol.103
, pp. 1961-1966
-
-
Miyato, H.1
Tsuno, N.H.2
Kitayama, J.3
-
40
-
-
84878889056
-
ROS production and NF-κB activation triggered by RAC1 facilitate WNT-driven intestinal stem cell proliferation and colorectal cancer initiation
-
Myant K.B., Cammareri P., McGhee E.J., Ridgway R.A., Huels D.J., Cordero J.B., Schwitalla S., Kalna G., Ogg E.L., Athineos D., et al. ROS production and NF-κB activation triggered by RAC1 facilitate WNT-driven intestinal stem cell proliferation and colorectal cancer initiation. Cell Stem Cell 2013, 12:761-773.
-
(2013)
Cell Stem Cell
, vol.12
, pp. 761-773
-
-
Myant, K.B.1
Cammareri, P.2
McGhee, E.J.3
Ridgway, R.A.4
Huels, D.J.5
Cordero, J.B.6
Schwitalla, S.7
Kalna, G.8
Ogg, E.L.9
Athineos, D.10
-
41
-
-
47949102937
-
The semaphorins: versatile regulators of tumour progression and tumour angiogenesis
-
Neufeld G., Kessler O. The semaphorins: versatile regulators of tumour progression and tumour angiogenesis. Nat. Rev. Cancer 2008, 8:632-645.
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 632-645
-
-
Neufeld, G.1
Kessler, O.2
-
42
-
-
0033552910
-
Anti-apoptotic function of Rac in hematopoietic cells
-
Nishida K., Kaziro Y., Satoh T. Anti-apoptotic function of Rac in hematopoietic cells. Oncogene 1999, 18:407-415.
-
(1999)
Oncogene
, vol.18
, pp. 407-415
-
-
Nishida, K.1
Kaziro, Y.2
Satoh, T.3
-
43
-
-
66149128126
-
The receptor interacting protein 1 inhibits p53 induction through NF-kappaB activation and confers a worse prognosis in glioblastoma
-
Park S., Hatanpaa K.J., Xie Y., Mickey B.E., Madden C.J., Raisanen J.M., Ramnarain D.B., Xiao G., Saha D., Boothman D.A., et al. The receptor interacting protein 1 inhibits p53 induction through NF-kappaB activation and confers a worse prognosis in glioblastoma. Cancer Res. 2009, 69:2809-2816.
-
(2009)
Cancer Res.
, vol.69
, pp. 2809-2816
-
-
Park, S.1
Hatanpaa, K.J.2
Xie, Y.3
Mickey, B.E.4
Madden, C.J.5
Raisanen, J.M.6
Ramnarain, D.B.7
Xiao, G.8
Saha, D.9
Boothman, D.A.10
-
44
-
-
79955679188
-
Eyes wide open: a critical review of sphere-formation as an assay for stem cells
-
Pastrana E., Silva-Vargas V., Doetsch F. Eyes wide open: a critical review of sphere-formation as an assay for stem cells. Cell Stem Cell 2011, 8:486-498.
-
(2011)
Cell Stem Cell
, vol.8
, pp. 486-498
-
-
Pastrana, E.1
Silva-Vargas, V.2
Doetsch, F.3
-
45
-
-
0038458973
-
Human malignant glioma cells express semaphorins and their receptors, neuropilins and plexins
-
Rieger J., Wick W., Weller M. Human malignant glioma cells express semaphorins and their receptors, neuropilins and plexins. Glia 2003, 42:379-389.
-
(2003)
Glia
, vol.42
, pp. 379-389
-
-
Rieger, J.1
Wick, W.2
Weller, M.3
-
46
-
-
67649939163
-
The increasing complexity of the cancer stem cell paradigm
-
Rosen J.M., Jordan C.T. The increasing complexity of the cancer stem cell paradigm. Science 2009, 324:1670-1673.
-
(2009)
Science
, vol.324
, pp. 1670-1673
-
-
Rosen, J.M.1
Jordan, C.T.2
-
47
-
-
79958265710
-
Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast
-
Scheel C., Eaton E.N., Li S.H., Chaffer C.L., Reinhardt F., Kah K.J., Bell G., Guo W., Rubin J., Richardson A.L., Weinberg R.A. Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast. Cell 2011, 145:926-940.
-
(2011)
Cell
, vol.145
, pp. 926-940
-
-
Scheel, C.1
Eaton, E.N.2
Li, S.H.3
Chaffer, C.L.4
Reinhardt, F.5
Kah, K.J.6
Bell, G.7
Guo, W.8
Rubin, J.9
Richardson, A.L.10
Weinberg, R.A.11
-
48
-
-
0036531793
-
Suppression of Rac activity induces apoptosis of human glioma cells but not normal human astrocytes
-
Senger D.L., Tudan C., Guiot M.C., Mazzoni I.E., Molenkamp G., LeBlanc R., Antel J., Olivier A., Snipes G.J., Kaplan D.R. Suppression of Rac activity induces apoptosis of human glioma cells but not normal human astrocytes. Cancer Res. 2002, 62:2131-2140.
-
(2002)
Cancer Res.
, vol.62
, pp. 2131-2140
-
-
Senger, D.L.1
Tudan, C.2
Guiot, M.C.3
Mazzoni, I.E.4
Molenkamp, G.5
LeBlanc, R.6
Antel, J.7
Olivier, A.8
Snipes, G.J.9
Kaplan, D.R.10
-
49
-
-
50849142558
-
Adult SVZ stem cells lie in a vascular niche: a quantitative analysis of niche cell-cell interactions
-
Shen Q., Wang Y., Kokovay E., Lin G., Chuang S.M., Goderie S.K., Roysam B., Temple S. Adult SVZ stem cells lie in a vascular niche: a quantitative analysis of niche cell-cell interactions. Cell Stem Cell 2008, 3:289-300.
-
(2008)
Cell Stem Cell
, vol.3
, pp. 289-300
-
-
Shen, Q.1
Wang, Y.2
Kokovay, E.3
Lin, G.4
Chuang, S.M.5
Goderie, S.K.6
Roysam, B.7
Temple, S.8
-
50
-
-
9244241576
-
Identification of human brain tumour initiating cells
-
Singh S.K., Hawkins C., Clarke I.D., Squire J.A., Bayani J., Hide T., Henkelman R.M., Cusimano M.D., Dirks P.B. Identification of human brain tumour initiating cells. Nature 2004, 432:396-401.
-
(2004)
Nature
, vol.432
, pp. 396-401
-
-
Singh, S.K.1
Hawkins, C.2
Clarke, I.D.3
Squire, J.A.4
Bayani, J.5
Hide, T.6
Henkelman, R.M.7
Cusimano, M.D.8
Dirks, P.B.9
-
51
-
-
70449687092
-
Hypoxia promotes expansion of the CD133-positive glioma stem cells through activation of HIF-1alpha
-
Soeda A., Park M., Lee D., Mintz A., Androutsellis-Theotokis A., McKay R.D., Engh J., Iwama T., Kunisada T., Kassam A.B., et al. Hypoxia promotes expansion of the CD133-positive glioma stem cells through activation of HIF-1alpha. Oncogene 2009, 28:3949-3959.
-
(2009)
Oncogene
, vol.28
, pp. 3949-3959
-
-
Soeda, A.1
Park, M.2
Lee, D.3
Mintz, A.4
Androutsellis-Theotokis, A.5
McKay, R.D.6
Engh, J.7
Iwama, T.8
Kunisada, T.9
Kassam, A.B.10
-
53
-
-
65349121788
-
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial
-
Stupp R., Hegi M.E., Mason W.P., van den Bent M.J., Taphoorn M.J., Janzer R.C., Ludwin S.K., Allgeier A., Fisher B., Belanger K., et al. Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial. Lancet Oncol. 2009, 10:459-466. European Organisation for Research and Treatment of Cancer Brain Tumour and Radiation Oncology Groups, National Cancer Institute of Canada Clinical Trials GroupNational Cancer Institute of Canada Clinical Trials Group.
-
(2009)
Lancet Oncol.
, vol.10
, pp. 459-466
-
-
Stupp, R.1
Hegi, M.E.2
Mason, W.P.3
van den Bent, M.J.4
Taphoorn, M.J.5
Janzer, R.C.6
Ludwin, S.K.7
Allgeier, A.8
Fisher, B.9
Belanger, K.10
-
54
-
-
84899524502
-
Reconstructing and reprogramming the tumor-propagating potential of glioblastoma stem-like cells
-
Suvà M.L., Rheinbay E., Gillespie S.M., Patel A.P., Wakimoto H., Rabkin S.D., Riggi N., Chi A.S., Cahill D.P., Nahed B.V., et al. Reconstructing and reprogramming the tumor-propagating potential of glioblastoma stem-like cells. Cell 2014, 157:580-594.
-
(2014)
Cell
, vol.157
, pp. 580-594
-
-
Suvà, M.L.1
Rheinbay, E.2
Gillespie, S.M.3
Patel, A.P.4
Wakimoto, H.5
Rabkin, S.D.6
Riggi, N.7
Chi, A.S.8
Cahill, D.P.9
Nahed, B.V.10
-
55
-
-
84865137629
-
Emerging role of semaphorins as major regulatory signals and potential therapeutic targets in cancer
-
Tamagnone L. Emerging role of semaphorins as major regulatory signals and potential therapeutic targets in cancer. Cancer Cell 2012, 22:145-152.
-
(2012)
Cancer Cell
, vol.22
, pp. 145-152
-
-
Tamagnone, L.1
-
56
-
-
72949100509
-
Secreted semaphorins control spine distribution and morphogenesis in the postnatal CNS
-
Tran T.S., Rubio M.E., Clem R.L., Johnson D., Case L., Tessier-Lavigne M., Huganir R.L., Ginty D.D., Kolodkin A.L. Secreted semaphorins control spine distribution and morphogenesis in the postnatal CNS. Nature 2009, 462:1065-1069.
-
(2009)
Nature
, vol.462
, pp. 1065-1069
-
-
Tran, T.S.1
Rubio, M.E.2
Clem, R.L.3
Johnson, D.4
Case, L.5
Tessier-Lavigne, M.6
Huganir, R.L.7
Ginty, D.D.8
Kolodkin, A.L.9
-
57
-
-
79959431137
-
The small GTPase Rac1 is a novel binding partner of Bcl-2 and stabilizes its antiapoptotic activity
-
Velaithan R., Kang J., Hirpara J.L., Loh T., Goh B.C., Le Bras M., Brenner C., Clement M.V., Pervaiz S. The small GTPase Rac1 is a novel binding partner of Bcl-2 and stabilizes its antiapoptotic activity. Blood 2011, 117:6214-6226.
-
(2011)
Blood
, vol.117
, pp. 6214-6226
-
-
Velaithan, R.1
Kang, J.2
Hirpara, J.L.3
Loh, T.4
Goh, B.C.5
Le Bras, M.6
Brenner, C.7
Clement, M.V.8
Pervaiz, S.9
-
59
-
-
69949104482
-
A genetically encoded photoactivatable Rac controls the motility of living cells
-
Wu Y.I., Frey D., Lungu O.I., Jaehrig A., Schlichting I., Kuhlman B., Hahn K.M. A genetically encoded photoactivatable Rac controls the motility of living cells. Nature 2009, 461:104-108.
-
(2009)
Nature
, vol.461
, pp. 104-108
-
-
Wu, Y.I.1
Frey, D.2
Lungu, O.I.3
Jaehrig, A.4
Schlichting, I.5
Kuhlman, B.6
Hahn, K.M.7
-
61
-
-
70349638289
-
Tumour-initiating cells: challenges and opportunities for anticancer drug discovery
-
Zhou B.B., Zhang H., Damelin M., Geles K.G., Grindley J.C., Dirks P.B. Tumour-initiating cells: challenges and opportunities for anticancer drug discovery. Nat. Rev. Drug Discov. 2009, 8:806-823.
-
(2009)
Nat. Rev. Drug Discov.
, vol.8
, pp. 806-823
-
-
Zhou, B.B.1
Zhang, H.2
Damelin, M.3
Geles, K.G.4
Grindley, J.C.5
Dirks, P.B.6
-
62
-
-
84874106416
-
The Rac1 splice form Rac1b promotes K-ras-induced lung tumorigenesis
-
Zhou C., Licciulli S., Avila J.L., Cho M., Troutman S., Jiang P., Kossenkov A.V., Showe L.C., Liu Q., Vachani A., et al. The Rac1 splice form Rac1b promotes K-ras-induced lung tumorigenesis. Oncogene 2013, 32:903-909.
-
(2013)
Oncogene
, vol.32
, pp. 903-909
-
-
Zhou, C.1
Licciulli, S.2
Avila, J.L.3
Cho, M.4
Troutman, S.5
Jiang, P.6
Kossenkov, A.V.7
Showe, L.C.8
Liu, Q.9
Vachani, A.10
-
63
-
-
80052795862
-
Endothelial cells create a stem cell niche in glioblastoma by providing NOTCH ligands that nurture self-renewal of cancer stem-like cells
-
Zhu T.S., Costello M.A., Talsma C.E., Flack C.G., Crowley J.G., Hamm L.L., He X., Hervey-Jumper S.L., Heth J.A., Muraszko K.M., et al. Endothelial cells create a stem cell niche in glioblastoma by providing NOTCH ligands that nurture self-renewal of cancer stem-like cells. Cancer Res. 2011, 71:6061-6072.
-
(2011)
Cancer Res.
, vol.71
, pp. 6061-6072
-
-
Zhu, T.S.1
Costello, M.A.2
Talsma, C.E.3
Flack, C.G.4
Crowley, J.G.5
Hamm, L.L.6
He, X.7
Hervey-Jumper, S.L.8
Heth, J.A.9
Muraszko, K.M.10
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