Pharmacological activity of a Bv8 analogue modified in position 24

British Journal of Pharmacology

Volumn 166, Issue 3, 2012, Pages 950-963

  Lattanzi, R ^a   Sacerdote, P ^b   Franchi, S ^b   Canestrelli, M ^a   Miele, R ^a   Barra, D ^a   Visentin, S ^c   Denuccio, C ^c   Porreca, F ^d   De Felice, M ^d   Guida, F ^e   Luongo, L ^e   De Novellis, V ^e   Maione, S ^e   Negri, L ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

^c ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^d UNIVERSITY OF ARIZONA   (United States)

^e SECOND UNIVERSITY OF NAPLES   (Italy)

Author keywords

anti hyperalgesic effect; Bv8; Bv8 analogues; chemotaxis; cytokine release; hyperalgesia; prokineticin receptors; prokineticins

Indexed keywords

ALANINE; BETA ENDORPHIN; ENDOCRINE GLAND DERIVED VASCULAR ENDOTHELIAL GROWTH FACTOR; GROWTH FACTOR; GROWTH FACTOR RECEPTOR; PEPTIDE A 24; PEPTIDE BV 8; PROKINETICIN 2; PROKINETICIN RECEPTOR 1; PROKINETICIN RECEPTOR 2; SYNTHETIC PEPTIDE; TRYPTOPHAN; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANALGESIC ACTIVITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING AFFINITY; BRAIN LEVEL; CHEMOTAXIS; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG STRUCTURE; HYPERALGESIA; IC 50; INFLAMMATION; MALE; MOLECULAR RECOGNITION; MOUSE; NOCICEPTION; NONHUMAN; PAIN THRESHOLD; PEPTIDE ANALYSIS; PRIORITY JOURNAL; RECEPTOR BLOCKING;

ALANINE; AMINO ACID SUBSTITUTION; AMPHIBIAN PROTEINS; ANALGESICS; ANIMALS; CHEMOTAXIS; CHO CELLS; CRICETINAE; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; EDEMA; HYPERALGESIA; LIGANDS; MACROPHAGES; MALE; MICE; NEUROPEPTIDES; PAIN, POSTOPERATIVE; PROTEIN BINDING; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, PEPTIDE; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION; TRYPTOPHAN;

EID: 84860860459     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2011.01797.x     Document Type: Article

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