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Volumn 131, Issue 5, 2014, Pages 645-654

Ceramide metabolism analysis in a model of binge drinking reveals both neuroprotective and toxic effects of ethanol

Author keywords

Alcohol; Binge drinking; Brain; Ceramide; Ethanol

Indexed keywords

ALCOHOL; CERAMIDE; CERAMIDE DEGRADING ENZYME; ENZYME; UNCLASSIFIED DRUG; CENTRAL DEPRESSANT AGENT; SPHINGOMYELIN;

EID: 84915786414     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/jnc.12834     Document Type: Article
Times cited : (17)

References (50)
  • 2
    • 0033215974 scopus 로고    scopus 로고
    • Ceramide signaling downstream of the p75 neurotrophin receptor mediates the effects of nerve growth factor on outgrowth of cultured hippocampal neurons
    • Brann A. B., Scott R., Neuberger Y., Abulafia D., Boldin S., Fainzilber M. and Futerman A. H. (1999) Ceramide signaling downstream of the p75 neurotrophin receptor mediates the effects of nerve growth factor on outgrowth of cultured hippocampal neurons. J. Neurosci. 19, 8199-8206.
    • (1999) J. Neurosci. , vol.19 , pp. 8199-8206
    • Brann, A.B.1    Scott, R.2    Neuberger, Y.3    Abulafia, D.4    Boldin, S.5    Fainzilber, M.6    Futerman, A.H.7
  • 3
    • 84860529500 scopus 로고    scopus 로고
    • Ethanol triggers sphingosine 1-phosphate elevation along with neuroapoptosis in the developing mouse brain
    • Chakraborty G., Saito M., Shah R., Mao R. F., Vadasz C. and Saito M. (2012) Ethanol triggers sphingosine 1-phosphate elevation along with neuroapoptosis in the developing mouse brain. J. Neurochem. 121, 806-817.
    • (2012) J. Neurochem. , vol.121 , pp. 806-817
    • Chakraborty, G.1    Saito, M.2    Shah, R.3    Mao, R.F.4    Vadasz, C.5    Saito, M.6
  • 4
    • 84860851620 scopus 로고    scopus 로고
    • Ethanol and adult CNS neurodamage: Oxidative stress, but possibly not excitotoxicity
    • Collins M. A. and Neafsey E. J. (2012) Ethanol and adult CNS neurodamage: oxidative stress, but possibly not excitotoxicity. Front. Biosci. (Elite Ed) 4, 1358-1367.
    • (2012) Front. Biosci. (Elite Ed) , vol.4 , pp. 1358-1367
    • Collins, M.A.1    Neafsey, E.J.2
  • 5
    • 0031939607 scopus 로고    scopus 로고
    • Brain damage due to episodic alcohol exposure in vivo and in vitro: Furosemide neuroprotection implicates edema-based mechanism
    • Collins M. A., Zou J. Y. and Neafsey E. J. (1998) Brain damage due to episodic alcohol exposure in vivo and in vitro: furosemide neuroprotection implicates edema-based mechanism. FASEB J. 12, 221-230.
    • (1998) FASEB J. , vol.12 , pp. 221-230
    • Collins, M.A.1    Zou, J.Y.2    Neafsey, E.J.3
  • 6
    • 0033057788 scopus 로고    scopus 로고
    • The P38 mitogen-activated protein kinase inhibitor SB203580 antagonizes the inhibitory effects of interleukin-1beta on long-term potentiation in the rat dentate gyrus in vitro
    • Coogan A. N., O'Neill L. A. and O'Connor J. J. (1999) The P38 mitogen-activated protein kinase inhibitor SB203580 antagonizes the inhibitory effects of interleukin-1beta on long-term potentiation in the rat dentate gyrus in vitro. Neuroscience 93, 57-69.
    • (1999) Neuroscience , vol.93 , pp. 57-69
    • Coogan, A.N.1    O'Neill, L.A.2    O'Connor, J.J.3
  • 7
    • 0031887547 scopus 로고    scopus 로고
    • Brain neuronal degeneration caused by episodic alcohol intoxication in rats: Effects of nimodipine, 6,7-dinitroquinoxaline- 2,3-dione, and MK-801
    • Corso T. D., Mostafa H. M., Collins M. A. and Neafsey E. J. (1998) Brain neuronal degeneration caused by episodic alcohol intoxication in rats: effects of nimodipine, 6,7-dinitroquinoxaline- 2,3-dione, and MK-801. Alcohol. Clin. Exp. Res. 22, 217-224.
    • (1998) Alcohol. Clin. Exp. Res. , vol.22 , pp. 217-224
    • Corso, T.D.1    Mostafa, H.M.2    Collins, M.A.3    Neafsey, E.J.4
  • 8
    • 10744222407 scopus 로고    scopus 로고
    • Alcohol-induced neurodegeneration: When, where and why?
    • Crews F. T., Collins M. A., Dlugos C. et al. (2004) Alcohol-induced neurodegeneration: when, where and why? Alcohol. Clin. Exp. Res. 28, 350-364.
    • (2004) Alcohol. Clin. Exp. Res. , vol.28 , pp. 350-364
    • Crews, F.T.1    Collins, M.A.2    Dlugos, C.3
  • 9
    • 0037121659 scopus 로고    scopus 로고
    • Nerve growth factor survival signaling in cultured hippocampal neurons is mediated through TrkA and requires the common neurotrophin receptor P75
    • Culmsee C., Gerling N., Lehmann M., Nikolova-Karakashian M., Prehn J. H., Mattson M. P. and Krieglstein J. (2002) Nerve growth factor survival signaling in cultured hippocampal neurons is mediated through TrkA and requires the common neurotrophin receptor P75. Neuroscience 115, 1089-1108.
    • (2002) Neuroscience , vol.115 , pp. 1089-1108
    • Culmsee, C.1    Gerling, N.2    Lehmann, M.3    Nikolova-Karakashian, M.4    Prehn, J.H.5    Mattson, M.P.6    Krieglstein, J.7
  • 10
    • 0034190230 scopus 로고    scopus 로고
    • Prenatal alcohol exposure increases TNFalpha-induced cytotoxicity in primary astrocytes
    • De Vito W. J., Xhaja K. and Stone S. (2000) Prenatal alcohol exposure increases TNFalpha-induced cytotoxicity in primary astrocytes. Alcohol 21, 63-71.
    • (2000) Alcohol , vol.21 , pp. 63-71
    • De Vito, W.J.1    Xhaja, K.2    Stone, S.3
  • 11
    • 80055116442 scopus 로고    scopus 로고
    • The effects of short-term chronic ethanol intoxication and ethanol withdrawal on the molecular composition of the rat hippocampus by FT-IR spectroscopy
    • Elibol-Can B., Jakubowska-Dogru E., Severcan M. and Severcan F. (2011) The effects of short-term chronic ethanol intoxication and ethanol withdrawal on the molecular composition of the rat hippocampus by FT-IR spectroscopy. Alcohol. Clin. Exp. Res. 35, 2050-2062.
    • (2011) Alcohol. Clin. Exp. Res. , vol.35 , pp. 2050-2062
    • Elibol-Can, B.1    Jakubowska-Dogru, E.2    Severcan, M.3    Severcan, F.4
  • 13
    • 0037450409 scopus 로고    scopus 로고
    • Modulation by C2 ceramide of the nicotinic transmission within the coeliac ganglion in the rabbit
    • Fasano C., Miolan J. P. and Niel J. P. (2003) Modulation by C2 ceramide of the nicotinic transmission within the coeliac ganglion in the rabbit. Neuroscience 116, 753-759.
    • (2003) Neuroscience , vol.116 , pp. 753-759
    • Fasano, C.1    Miolan, J.P.2    Niel, J.P.3
  • 14
    • 0031970196 scopus 로고    scopus 로고
    • The transcription factor NFkappaB mediates increases in calcium currents and decreases in NMDA- and AMPA/kainate-induced currents induced by tumor necrosis factor-alpha in hippocampal neurons
    • Furukawa K. and Mattson M. P. (1998) The transcription factor NFkappaB mediates increases in calcium currents and decreases in NMDA- and AMPA/kainate-induced currents induced by tumor necrosis factor-alpha in hippocampal neurons. J. Neurochem. 70, 1876-1886.
    • (1998) J. Neurochem. , vol.70 , pp. 1876-1886
    • Furukawa, K.1    Mattson, M.P.2
  • 15
    • 0031866963 scopus 로고    scopus 로고
    • Ceramide and its interconvertible metabolite sphingosine function as indispensable lipid factors involved in survival and dendritic differentiation of cerebellar Purkinje cells
    • Furuya S., Mitoma J., Makino A. and Hirabayashi Y. (1998) Ceramide and its interconvertible metabolite sphingosine function as indispensable lipid factors involved in survival and dendritic differentiation of cerebellar Purkinje cells. J. Neurochem. 71, 366-377.
    • (1998) J. Neurochem. , vol.71 , pp. 366-377
    • Furuya, S.1    Mitoma, J.2    Makino, A.3    Hirabayashi, Y.4
  • 16
    • 84868103665 scopus 로고    scopus 로고
    • Recruitment of medial prefrontal cortex neurons during alcohol withdrawal predicts cognitive impairment and excessive alcohol drinking
    • George O., Sanders C., Freiling J., Grigoryan E., Vu S., Allen C. D., Crawford E., Mandyam C. D. and Koob G. F. (2012) Recruitment of medial prefrontal cortex neurons during alcohol withdrawal predicts cognitive impairment and excessive alcohol drinking. Proc Natl Acad Sci U S A 109, 18156-18161.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 18156-18161
    • George, O.1    Sanders, C.2    Freiling, J.3    Grigoryan, E.4    Vu, S.5    Allen, C.D.6    Crawford, E.7    Mandyam, C.D.8    Koob, G.F.9
  • 18
    • 84881150853 scopus 로고    scopus 로고
    • Oxidized phospholipids induce ceramide accumulation in RAW 264.7 macrophages: Role of ceramide synthases
    • Halasiddappa L. M., Koefeler H., Futerman A. H. and Hermetter A. (2013) Oxidized phospholipids induce ceramide accumulation in RAW 264.7 macrophages: role of ceramide synthases. PLoS ONE 8, e70002.
    • (2013) PLoS ONE , vol.8 , pp. e70002
    • Halasiddappa, L.M.1    Koefeler, H.2    Futerman, A.H.3    Hermetter, A.4
  • 19
    • 0030448021 scopus 로고    scopus 로고
    • Functions of ceramide in coordinating cellular responses to stress
    • Hannun Y. A. (1996) Functions of ceramide in coordinating cellular responses to stress. Science 274, 1855-1859.
    • (1996) Science , vol.274 , pp. 1855-1859
    • Hannun, Y.A.1
  • 22
    • 84877139062 scopus 로고    scopus 로고
    • Folate stress induces apoptosis via p53-dependent de novo ceramide synthesis and up-regulation of ceramide synthase 6
    • Hoeferlin L. A., Fekry B., Ogretmen B., Krupenko S. A. and Krupenko N. I. (2013) Folate stress induces apoptosis via p53-dependent de novo ceramide synthesis and up-regulation of ceramide synthase 6. J. Biol. Chem. 288, 12880-12890.
    • (2013) J. Biol. Chem. , vol.288 , pp. 12880-12890
    • Hoeferlin, L.A.1    Fekry, B.2    Ogretmen, B.3    Krupenko, S.A.4    Krupenko, N.I.5
  • 23
    • 0027763251 scopus 로고
    • Are binge drinkers more at risk of developing brain damage?
    • Hunt W. A. (1993) Are binge drinkers more at risk of developing brain damage? Alcohol 10, 559-561.
    • (1993) Alcohol , vol.10 , pp. 559-561
    • Hunt, W.A.1
  • 24
    • 0031903951 scopus 로고    scopus 로고
    • A synthetic ceramide analog (L-PDMP) up-regulates neuronal function
    • Inokuchi J., Mizutani A., Jimbo M. et al. (1998) A synthetic ceramide analog (L-PDMP) up-regulates neuronal function. Ann. N. Y. Acad. Sci. 845, 219-224.
    • (1998) Ann. N. Y. Acad. Sci. , vol.845 , pp. 219-224
    • Inokuchi, J.1    Mizutani, A.2    Jimbo, M.3
  • 25
    • 0029049833 scopus 로고
    • Ceramide prevents neuronal programmed cell death induced by nerve growth factor deprivation
    • Ito A. and Horigome K. (1995) Ceramide prevents neuronal programmed cell death induced by nerve growth factor deprivation. J. Neurochem. 65, 463-466.
    • (1995) J. Neurochem. , vol.65 , pp. 463-466
    • Ito, A.1    Horigome, K.2
  • 26
    • 84875875885 scopus 로고    scopus 로고
    • Neurotoxic effects of alcohol in adolescence
    • Jacobus J. and Tapert S. F. (2013) Neurotoxic effects of alcohol in adolescence. Annu. Rev. Clin. Psychol. 9, 703-721.
    • (2013) Annu. Rev. Clin. Psychol. , vol.9 , pp. 703-721
    • Jacobus, J.1    Tapert, S.F.2
  • 31
    • 0347695003 scopus 로고    scopus 로고
    • Ceramide pathways modulate ethanol-induced cell death in astrocytes
    • Pascual M., Valles S. L., Renau-Piqueras J. and Guerri C. (2003) Ceramide pathways modulate ethanol-induced cell death in astrocytes. J. Neurochem. 87, 1535-1545.
    • (2003) J. Neurochem. , vol.87 , pp. 1535-1545
    • Pascual, M.1    Valles, S.L.2    Renau-Piqueras, J.3    Guerri, C.4
  • 32
    • 0029748324 scopus 로고    scopus 로고
    • Development and application of a physiologically based pharmacokinetic model for ethanol in the mouse
    • Pastino G. M., Sultatos L. G. and Flynn E. J. (1996) Development and application of a physiologically based pharmacokinetic model for ethanol in the mouse. Alcohol Alcohol. 31, 365-374.
    • (1996) Alcohol Alcohol. , vol.31 , pp. 365-374
    • Pastino, G.M.1    Sultatos, L.G.2    Flynn, E.J.3
  • 33
    • 0034973508 scopus 로고    scopus 로고
    • Reorganization of frontal systems used by alcoholics for spatial working memory: An fMRI study
    • Pfefferbaum A., Desmond J. E., Galloway C., Menon V., Glover G. H. and Sullivan E. V. (2001) Reorganization of frontal systems used by alcoholics for spatial working memory: an fMRI study. Neuroimage 14, 7-20.
    • (2001) Neuroimage , vol.14 , pp. 7-20
    • Pfefferbaum, A.1    Desmond, J.E.2    Galloway, C.3    Menon, V.4    Glover, G.H.5    Sullivan, E.V.6
  • 34
    • 0032532298 scopus 로고    scopus 로고
    • Ceramide can induce cell death in sensory neurons, whereas ceramide analogues and sphingosine promote survival
    • Ping S. E. and Barrett G. L. (1998) Ceramide can induce cell death in sensory neurons, whereas ceramide analogues and sphingosine promote survival. J. Neurosci. Res. 54, 206-213.
    • (1998) J. Neurosci. Res. , vol.54 , pp. 206-213
    • Ping, S.E.1    Barrett, G.L.2
  • 35
    • 11844289551 scopus 로고    scopus 로고
    • Evaluation of a simple model of ethanol drinking to intoxication in C57BL/6J mice
    • Rhodes J. S., Best K., Belknap J. K., Finn D. A. and Crabbe J. C. (2005) Evaluation of a simple model of ethanol drinking to intoxication in C57BL/6J mice. Physiol. Behav. 84, 53-63.
    • (2005) Physiol. Behav. , vol.84 , pp. 53-63
    • Rhodes, J.S.1    Best, K.2    Belknap, J.K.3    Finn, D.A.4    Crabbe, J.C.5
  • 36
    • 24144486191 scopus 로고    scopus 로고
    • Ethanol-induced changes in the content of triglycerides, ceramides, and glucosylceramides in cultured neurons
    • Saito M., Cooper T. B. and Vadasz C. (2005) Ethanol-induced changes in the content of triglycerides, ceramides, and glucosylceramides in cultured neurons. Alcohol. Clin. Exp. Res. 29, 1374-1383.
    • (2005) Alcohol. Clin. Exp. Res. , vol.29 , pp. 1374-1383
    • Saito, M.1    Cooper, T.B.2    Vadasz, C.3
  • 37
    • 35248901859 scopus 로고    scopus 로고
    • Ethanol alters lipid profiles and phosphorylation status of AMP-activated protein kinase in the neonatal mouse brain
    • Saito M., Chakraborty G., Mao R. F., Wang R., Cooper T. B. and Vadasz C. (2007) Ethanol alters lipid profiles and phosphorylation status of AMP-activated protein kinase in the neonatal mouse brain. J. Neurochem. 103, 1208-1218.
    • (2007) J. Neurochem. , vol.103 , pp. 1208-1218
    • Saito, M.1    Chakraborty, G.2    Mao, R.F.3    Wang, R.4    Cooper, T.B.5    Vadasz, C.6
  • 38
    • 77956568190 scopus 로고    scopus 로고
    • Involvement of ceramide in ethanol-induced apoptotic neurodegeneration in the neonatal mouse brain
    • Saito M., Chakraborty G., Hegde M., Ohsie J., Paik S. M. and Vadasz C. (2010) Involvement of ceramide in ethanol-induced apoptotic neurodegeneration in the neonatal mouse brain. J. Neurochem. 115, 168-177.
    • (2010) J. Neurochem. , vol.115 , pp. 168-177
    • Saito, M.1    Chakraborty, G.2    Hegde, M.3    Ohsie, J.4    Paik, S.M.5    Vadasz, C.6
  • 39
    • 24144471293 scopus 로고    scopus 로고
    • Cross-talk between phosphatidic acid and ceramide during ethanol-induced apoptosis in astrocytes
    • Schatter B., Jin S., Loffelholz K. and Klein J. (2005) Cross-talk between phosphatidic acid and ceramide during ethanol-induced apoptosis in astrocytes. BMC Pharmacol. 5, 3.
    • (2005) BMC Pharmacol. , vol.5 , pp. 3
    • Schatter, B.1    Jin, S.2    Loffelholz, K.3    Klein, J.4
  • 40
    • 0030949124 scopus 로고    scopus 로고
    • Functional rafts in cell membranes
    • Simons K. and Ikonen E. (1997) Functional rafts in cell membranes. Nature 387, 569-572.
    • (1997) Nature , vol.387 , pp. 569-572
    • Simons, K.1    Ikonen, E.2
  • 41
    • 16844381715 scopus 로고    scopus 로고
    • Striatal and forebrain nuclei volumes: Contribution to motor function and working memory deficits in alcoholism
    • Sullivan E. V., Deshmukh A., De Rosa E., Rosenbloom M. J. and Pfefferbaum A. (2005) Striatal and forebrain nuclei volumes: contribution to motor function and working memory deficits in alcoholism. Biol. Psychiatry 57, 768-776.
    • (2005) Biol. Psychiatry , vol.57 , pp. 768-776
    • Sullivan, E.V.1    Deshmukh, A.2    De Rosa, E.3    Rosenbloom, M.J.4    Pfefferbaum, A.5
  • 42
    • 3543085572 scopus 로고    scopus 로고
    • Ganglioside/glycosphingolipid turnover: New concepts
    • Tettamanti G. (2004) Ganglioside/glycosphingolipid turnover: new concepts. Glycoconj. J. 20, 301-317.
    • (2004) Glycoconj. J. , vol.20 , pp. 301-317
    • Tettamanti, G.1
  • 43
    • 0036519365 scopus 로고    scopus 로고
    • Trends in college binge drinking during a period of increased prevention efforts. Findings from 4 Harvard School of Public Health College Alcohol Study surveys: 1993-2001
    • Wechsler H., Lee J. E., Kuo M., Seibring M., Nelson T. F. and Lee H. (2002) Trends in college binge drinking during a period of increased prevention efforts. Findings from 4 Harvard School of Public Health College Alcohol Study surveys: 1993-2001. J. Am. Coll. Health 50, 203-217.
    • (2002) J. Am. Coll. Health , vol.50 , pp. 203-217
    • Wechsler, H.1    Lee, J.E.2    Kuo, M.3    Seibring, M.4    Nelson, T.F.5    Lee, H.6
  • 44
    • 65549128703 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha-induced neutral sphingomyelinase-2 modulates synaptic plasticity by controlling the membrane insertion of NMDA receptors
    • Wheeler D., Knapp E., Bandaru V. V., Wang Y., Knorr D., Poirier C., Mattson M. P., Geiger J. D. and Haughey N. J. (2009) Tumor necrosis factor-alpha-induced neutral sphingomyelinase-2 modulates synaptic plasticity by controlling the membrane insertion of NMDA receptors. J. Neurochem. 109, 1237-1249.
    • (2009) J. Neurochem. , vol.109 , pp. 1237-1249
    • Wheeler, D.1    Knapp, E.2    Bandaru, V.V.3    Wang, Y.4    Knorr, D.5    Poirier, C.6    Mattson, M.P.7    Geiger, J.D.8    Haughey, N.J.9
  • 45
    • 0033982663 scopus 로고    scopus 로고
    • Ceramide-induced sustained depression of synaptic currents mediated by ionotropic glutamate receptors in the hippocampus: An essential role of postsynaptic protein phosphatases
    • Yang S. N. (2000) Ceramide-induced sustained depression of synaptic currents mediated by ionotropic glutamate receptors in the hippocampus: an essential role of postsynaptic protein phosphatases. Neuroscience 96, 253-258.
    • (2000) Neuroscience , vol.96 , pp. 253-258
    • Yang, S.N.1
  • 46
    • 0034488193 scopus 로고    scopus 로고
    • Pivotal role for acidic sphingomyelinase in cerebral ischemia-induced ceramide and cytokine production, and neuronal apoptosis
    • Yu Z. F., Nikolova-Karakashian M., Zhou D., Cheng G., Schuchman E. H. and Mattson M. P. (2000) Pivotal role for acidic sphingomyelinase in cerebral ischemia-induced ceramide and cytokine production, and neuronal apoptosis. J. Mol. Neurosci. 15, 85-97.
    • (2000) J. Mol. Neurosci. , vol.15 , pp. 85-97
    • Yu, Z.F.1    Nikolova-Karakashian, M.2    Zhou, D.3    Cheng, G.4    Schuchman, E.H.5    Mattson, M.P.6
  • 47
    • 84855340424 scopus 로고    scopus 로고
    • Sphingosine kinase 2 mediates cerebral preconditioning and protects the mouse brain against ischemic injury
    • Yung L. M., Wei Y., Qin T., Wang Y., Smith C. D. and Waeber C. (2012) Sphingosine kinase 2 mediates cerebral preconditioning and protects the mouse brain against ischemic injury. Stroke 43, 199-204.
    • (2012) Stroke , vol.43 , pp. 199-204
    • Yung, L.M.1    Wei, Y.2    Qin, T.3    Wang, Y.4    Smith, C.D.5    Waeber, C.6
  • 48
    • 77950369644 scopus 로고    scopus 로고
    • Brain injury and recovery following binge ethanol: Evidence from in vivo magnetic resonance spectroscopy
    • Zahr N. M., Mayer D., Rohlfing T. et al. (2010) Brain injury and recovery following binge ethanol: evidence from in vivo magnetic resonance spectroscopy. Biol. Psychiatry 67, 846-854.
    • (2010) Biol. Psychiatry , vol.67 , pp. 846-854
    • Zahr, N.M.1    Mayer, D.2    Rohlfing, T.3
  • 50
    • 0029808495 scopus 로고    scopus 로고
    • Binge ethanol-induced brain damage in rats: Effect of inhibitors of nitric oxide synthase
    • Zou J. Y., Martinez D. B., Neafsey E. J. and Collins M. A. (1996) Binge ethanol-induced brain damage in rats: effect of inhibitors of nitric oxide synthase. Alcohol. Clin. Exp. Res. 20, 1406-1411.
    • (1996) Alcohol. Clin. Exp. Res. , vol.20 , pp. 1406-1411
    • Zou, J.Y.1    Martinez, D.B.2    Neafsey, E.J.3    Collins, M.A.4


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