Midbrain-driven emotion and reward processing in alcoholism

Neuropsychopharmacology

Volumn 38, Issue 10, 2013, Pages 1844-1853

  Muller Oehring E M ^a,b   Jung, Y C ^b,c   Sullivan, E V ^b   Hawkes, W C ^a,b   Pfefferbaum, A ^a,b   Schulte, T ^a  

^a SRI INTERNATIONAL   (United States)

^b STANFORD UNIVERSITY   (United States)

^c Yonsei University College of Medicine   (South Korea)

Author keywords

alcohol; Alcohol Use Disorder; automatic attentional bias; emotion; functional connectivity; functional MRI; Stroop task

Indexed keywords

ALCOHOL;

ADULT; AGED; ALCOHOLISM; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CUNEUS; ELECTROENCEPHALOGRAM; EMOTION; FEMALE; HUMAN; MALE; MESENCEPHALON; NUCLEAR MAGNETIC RESONANCE IMAGING; PARAHIPPOCAMPAL GYRUS; POSTERIOR CINGULATE; PRIORITY JOURNAL; REWARD; STROOP TEST;

ADULT; AGED; ALCOHOLISM; BEHAVIOR, ADDICTIVE; BRAIN MAPPING; CASE-CONTROL STUDIES; COLOR PERCEPTION; EMOTIONS; FEMALE; HUMANS; MALE; MESENCEPHALON; MIDDLE AGED; NEURAL INHIBITION; PHOTIC STIMULATION; REWARD; STROOP TEST; VISUAL PERCEPTION;

EID: 84882454197     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2013.102     Document Type: Article

References (70)

1. American Psychiatric Association (2000). Diagnostic and Statistical Manual of Mental Disorders. 4th ed. American Psychiatric Press: Washington, DC.
2. Beck AT, Steer RA, Brown GK (1996). Manual for the Beck Depression Inventory-II. Psychological Corporation: San Antonio, TX.
3. Benjamini Y, Drai D, Elmer G, Kafkafi N, Golani I (2001). Controlling the false discovery rate in behavior genetics research. Beh Brain Res 125: 279-284.
4. Beresford TP, Arciniegas DB, Alfers J, Clapp L, Martin B, Du Y et al (2006). Hippocampus volume loss due to chronic heavy drinking. Alcohol Clin Exp Res 30: 1866-1870.
5. Berridge KC, Robinson TE (2003). Parsing reward. Trends Neurosci 26: 507-513.
6. Bowirrat A, Oscar-Berman M (2005). Relationship between dopaminergic neurotransmission, alcoholism, and Reward Deficiency syndrome. Am J Med Genet B Neuropsychiatr Genet 132B: 29-37, Review.
7. Bush G, Luu P, Posner MI (2000). Cognitive and emotional influences in anterior cingulate cortex. Trends Cogn Sci 4: 215-222.
8. Clark US, Oscar-Berman M, Shagrin B, Pencina M. (2007). Alcoholism and judgments of affective stimuli. Neuropsychology 21: 346-362.
9. Cohen JD, MacWhinney B, Flatt M, Provost J (1993). PsyScope: A new graphic interactive environment for designing psychology experiments. Beh Res Methods Instrum Comput 25: 257-271.
10. Colibazzi T, Posner J, Wang Z, Gorman D, Gerber A, Yu S et al (2010). Neural systems subserving valence and arousal during the experience of induced emotions. Emotion 10: 377-389.
11. Courtney KE, Ghahremani DG, Ray LA (2012). Fronto-striatal functional connectivity during response inhibition in alcohol dependence. Addict Biol 18: 593-604.
12. De Rosa E, Desmond JE, Anderson AK, Pfefferbaum A, Sullivan EV (2004). The human basal forebrain integrates the old and the new. Neuron 41: 825-837.
13. Devinsky O, Morrell MJ, Vogt BA (1995). Contributions of anterior cingulate cortex to behaviour. Brain 118: 279-306.
14. Di Chiara G (2002). Nucleus accumbens shell and core dopamine: differential role in behavior and addiction. Behav Brain Res 137: 75-114.
15. Evert DL, Oscar-Berman M (2001). Selective attentional processing and the right hemisphere: effects of aging and alcoholism. Neuropsychology 15: 452-461.
16. Fein G, Chang M (2006). Visual P300s in long-term abstinent chronic alcoholics. Alcohol Clin Exp Res 30: 2000-2007.
17. Field M, Mogg K, Mann B, Bennett GA, Bradley BP (2012). Attentional Biases in Abstinent Alcoholics and Their Association With Craving. Psychol Addict Behav 27: 71-80.
18. Fitzgerald DA, Angstadt M, Jelsone LM, Nathan PJ, Phan KL (2006). Beyond threat: amygdala reactivity across multiple expressions of facial affect. Neuroimage 30: 1441-1448.
19. Foisy ML, Kornreich C, Fobe A, D'Hondt L, Pelc I, Hanak C et al (2007). Impaired emotional facial expression recognition in alcohol dependence: do these deficits persist with midterm abstinence? Alcohol Clin Exp Res 31: 404-410.
20. Friston KJ, Frith CD, Frackowiak RS, Turner R (1995). Characterizing dynamic brain responses with fMRI: a multivariate approach. Neuroimage 2: 166-172.
21. Friston KJ, Penny WD, Glaser DE (2005). Conjunction revisited. Neuroimage 25: 661-667.
22. Gainotti G (2001). Disorders of emotional behaviour. J Neurol 248: 743-749.
23. Gilman JM, Hommer DW (2008). Modulation of brain response to emotional images by alcohol cues in alcohol-dependent patients. Addict Biol 13: 423-434.
24. Gilman JM, Ramchandani VA, Davis MB, Bjork JM, Hommer DW (2008). Why we like to drink: a functional magnetic resonance imaging study of the rewarding and anxiolytic effects of alcohol. J Neurosci 28: 4583-4591.
25. Glahn DC, Lovallo WR, Fox PT (2007). Reduced amygdala activation in young adults at high risk of alcoholism: studies from the Oklahoma Family Health Patterns Project. Biol Psychiatry 61: 1306-1309.
26. Golkar A, Lonsdorf TB, Olsson A, Lindstrom KM, Berrebi J, Fransson P et al (2012). Distinct contributions of the dorsolateral prefrontal and orbitofrontal cortex during emotion regulation. PLoS One 7: e48107.
27. Grüsser SM, Wrase J, Klein S, Hermann D, Smolka MN, Ruf M et al (2004). Cue-induced activation of the striatum and medial prefrontal cortex is associated with subsequent relapse in abstinent alcoholics. Psychopharmacology (Berl) 175: 296-302.
28. Heinz A, Wrase J, Kahnt T, Beck A, Bromand Z, Grüsser SM et al (2007). Brain activation elicited by affectively positive stimuli is associated with a lower risk of relapse indetoxified alcoholic subjects. Alcohol Clin Exp Res 31: 1138-1147.
29. Heinz A, Beck A, Mir J, Grüsser SM, Grace AA, Wrase J (2010). Alcohol craving and relapse prediction: imaging studies In: Kuhn CM, Koob GF (eds) Advances in the Neuroscience of Addiction. 2nd edn. Chapter 4. Frontiers in Neuroscience. CRC Press: Boca Raton (FL).
30. Frontiers in Neuroscience. CRC Press: Boca Raton (FL). Johnsen BH, Laberg JC, Cox WM, Vaksdal A, Hugdahl K (1994). Alcoholic subjects' attentional bias in the processing of alcoholrelated words. Psychol Addict Behav 8: 111-115.
31. Koob GF, Volkow ND (2010). Neurocircuitry of addiction. Neuropsychopharmacology 35: 217-238.
32. Le Berre AP, Rauchs G, La Joie R, Mézenge F, Boudehent C, Vabret F et al (2012). Impaired decision-making and brain shrinkage in alcoholism. Eur Psychiatry [Epub ahead of print].
33. Liddell BJ, Brown KJ, Kemp AH, Barton MJ, Das P, Peduto A et al (2005). A direct brainstem-amygdala-cortical 'alarm' system for subliminal signals of fear. Neuroimage 24: 235-243.
34. Makris N, Oscar-Berman M, Jaffin SK, Hodge SM, Kennedy DN, Caviness VS et al (2008). Decreased volume of the brain reward system in alcoholism. Biol Psychiatry 64: 192-202.
35. Mann K, Agartz I, Harper C, Shoaf S, Rawlings RR, Momenan R et al (2001). Neuroimaging in alcoholism: ethanol and brain damage. Alcohol Clin Exp Res 25, (5 Suppl ISBRA) 104S-109S.
36. Marinkovic K, Oscar-Berman M, Urban T, O'Reilly CE, Howard JA, Sawyer K et al (2009). Alcoholism and dampened temporal limbic activation to emotional faces. Alcohol Clin Exp Res 33: 1880-1892.
37. Martinez D, Gil R, Slifstein M, Hwang DR, Huang Y, Perez A et al (2005). Alcohol dependence is associated with blunted dopamine transmission in the ventral striatum. Biol Psychiatry 58: 779-786.
38. Maurage P, Grynberg D, Noe?l X, Joassin F, Hanak C, Verbanck P et al (2011). The 'Reading the Mind in the Eyes' test as a new way to explore complex emotions decoding in alcohol dependence. Psychiatry Res 190: 375-378.
39. Montagne B, Kessels RP, Wester AJ, de Haan EH (2006). Processing of emotional facial expressions in Korsakoff's syndrome. Cortex 42: 705-710.
40. Morrison SE, Salzman CD (2009). The convergence of information about rewarding and aversive stimuli in single neurons. J Neurosci 29: 11471-11483.
41. Müller-Oehring EM, Schulte T, Fama R, Pfefferbaum A, Sullivan EV (2009). Global-local interference is related to callosal compromise in alcoholism: a behavior-DTI association study. Alcohol Clin Exp Res 33: 477-489.
42. Nichols T, Brett M, Andersson J, Wager T, Poline JB (2005). Valid conjunction inference with the minimum statistic. Neuroimage 25: 653-660.
43. Oberlin BG, Dzemidzic M, Bragulat V, Lehigh CA, Talavage T, O'Connor SJ et al (2012). Limbic responses to reward cues correlate with antisocial trait density in heavy drinkers. Neuroimage 60: 644-652 s.
44. O'Daly OG, Trick L, Scaife J, Marshall J, Ball D, Phillips ML et al (2012; Withdrawal-associated increases and decreases in functional neural connectivity associated with altered emotional regulation in alcoholism. Neuropsychopharmacology 37: 2267-2276.
45. Oscar-Berman M, Hancock M, Mildworf B, Hutner N, Weber DA (1990). Emotional perception and memory in alcoholism and aging. Alcohol Clin Exp Res 14: 383-393.
46. Oscar-Berman M (2000). Neuropsychological vulnerabilities in chronic alcoholism. In: Noronha A, Eckardt MJ. Warren K (eds). Review of NIAAA's Neuroscience and Behavioral Research Portfolio Vol. Monograph No. 34 (Department of Health and Human Services: Bethesda, MD, USA, pp 437-471.
47. Oscar-Berman M, Bowirrat A (2005). Genetic influences in emotional dysfunction and alcoholism-related brain damage. Neuropsychiatr Dis Treat 1: 211-229.
48. Perra S, Clements MA, Bernier BE, Morikawa H (2011). In vivo ethanol experience increases D(2) autoinhibition in the ventral tegmental area. Neuropsychopharmacology 36: 993-1002.
49. Phillips SC, Harper CG, Kril J (1987). A quantitative histological study of the cerebellar vermis in alcoholic patients. Brain 110: 301-314.
50. Phillips ML, Ladouceur CD, Drevets WC (2008). A neural model of voluntary and automatic emotion regulation: implications for understanding the pathophysiology and neurodevelopment of bipolar disorder. Mol Psychiatry 13: 833-857.
51. Pfefferbaum A, Sullivan EV, Mathalon DH, Lim KO (1997). Frontal lobe volume loss observed with magnetic resonance imaging in older chronic alcoholics. Alcohol Clin Exp Res 21: 521-529.
52. Poline JB, Worsley KJ, Evans AC, Friston KJ (1997). Combining spatial extent and peak intensity to test for activations in functional imaging. Neuroimage 5: 83-96.
53. Salloum JB, Ramchandani VA, Bodurka J, Rawlings R, Momenan R, George D et al (2007). Blunted rostral anterior cingulate response during a simplified decoding task of negative emotional facial expressions in alcoholic patients. Alcohol Clin Exp Res 31: 1490-1504.
54. Schacht JP, Anton RF, Myrick H (2013). Functional neuroimaging studies of alcohol cue reactivity: a quantitative meta-analysis and systematic review. Addict Biol 18: 121-133.
55. Schneider F, Habel U, Wagner M, Franke P, Salloum JB, Shah NJ et al (2001). Subcortical correlates of craving in recently abstinent alcoholic patients. Am J Psychiatry 158: 1075-1083.
56. Schulte T, Mueller-Oehring EM, Rosenbloom MJ, Pfefferbaum A, Sullivan EV (2005). Differential effect of HIV infection and alcoholism on conflict processing, attentional allocation, and perceptual load: evidence from a Stroop Match-to-Sample task. Biol Psychiatry 57: 67-75.
57. Schulte T, Müller-Oehring EM, Javitz H, Pfefferbaum A, Sullivan EV (2008). Callosal compromise differentially affects conflict processing and attentional allocation in alcoholism, HIV, and their comorbidity. Brain Imaging Behav 2: 27-38.
58. Schulte T, Müller-Oehring EM, Pfefferbaum A, Sullivan EV (2010). Neurocircuitry of emotion and cognition in alcoholism: contributions from white matter fiber tractography. Dialogues Clin Neurosci 12: 554-560.
59. Schulte T, Müller-Oehring EM, Sullivan EV, Pfefferbaum A (2011). Disruption of emotion and conflict processing in HIV infection with and without alcoholism comorbidity. J Int Neuropsychol Soc 22: 1-14.
60. Schulte T, Müller-Oehring EM, Sullivan EV, Pfefferbaum A (2012). Synchrony of corticostriatal-midbrain activation enables normal inhibitory control and conflict processing in recovering alcoholic men. Biol Psychiatry 71: 269-278.
61. Schulte T, Müller-Oehring EM, Vinco S, Hoeft F, Pfefferbaum A, Sullivan EV (2009). Double dissociation between actiondriven and perception-driven conflict resolution invoking anterior versus posterior brain systems. Neuroimage 48: 381-390.
62. Sinha R, Li CS (2007). Imaging stress- and cue-induced drug and alcohol craving: association with relapse and clinical implications. Drug Alcohol Rev 26: 25-31.
63. Spielberger CD, Gorsuch RL, Lushene R, Vagg PR, Jacobs GA (1983). Manual for the State-Trait Anxiety Inventory. Consulting Psychologists Press: Palo Alto, CA.
64. Sullivan EV, Rosenbloom MJ, Lim KO, Pfefferbaum A (2000). Longitudinal changes in cognition, gait, and balance in abstinent and relapsed alcoholic men: relationships to changes in brain structure. Neuropsychology 14: 178-188.
65. Sullivan EV, Harding AJ, Pentney R, Dlugos C, Martin PR, Parks MH et al (2003). Disruption of frontocerebellar circuitry and function in alcoholism. Alcohol Clin Exp Res 27: 301-309.
66. Sullivan EV, Deshmukh A, De Rosa E, Rosenbloom MJ, Pfefferbaum A (2005). Striatal and forebrain nuclei volumes: contribution to motor function and working memory deficits in alcoholism. Biol Psychiatry 57: 768-776.
67. Townshend JM, Duka T (2003). Mixed emotions: alcoholics' impairments in the recognition of specific emotional facial expressions. Neuropsychologia 41: 773-782.
68. Volkow ND, Wang GJ, Telang F, Fowler JS, Logan J, Jayne M et al (2007). Profound decreases in dopamine release in striatum in detoxified alcoholics: possible orbitofrontal involvement. J Neurosci 27: 12700-12706.
69. Vollstädt-Klein S, Loeber S, Richter A, Kirsch M, Bach P, von der Goltz C et al (2012). Validating incentive salience with functional magnetic resonance imaging: association between mesolimbic cue reactivity and attentional bias in alcohol-dependent patients. Addict Biol 17: 807-816.
70. Wrase J, Makris N, Braus DF, Mann K, Smolka MN, Kennedy DN et al (2008). Amygdala volume associated with alcohol abuse relapse and craving. Am J Psychiatry 165: 1179-1184..