Glutamine synthetase desensitizes differentiated adipocytes to proinflammatory stimuli by raising intracellular glutamine levels

FEBS Letters

Volumn 588, Issue 24, 2014, Pages 4807-4814

  Palmieri, Erika Mariana ^a   Spera, Iolanda ^a   Menga, Alessio ^a   Infantino, Vittoria ^b   Iacobazzi, Vito ^a,c   Castegna, Alessandra ^a  

^a UNIVERSITY OF BARI   (Italy)

^b UNIVERSITY OF BASILICATA   (Italy)

^c CNR   (Italy)

Author keywords

Adipocyte; Glutamine; Glutamine synthetase; Inflammation; Metabolic syndrome

Indexed keywords

DEXAMETHASONE; GLUTAMATE AMMONIA LIGASE; GLUTAMINE; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TRIACYLGLYCEROL;

ADIPOCYTE; ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL FUNCTION; CELL LEVEL; CELL MATURATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DESENSITIZATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME MECHANISM; GLUTAMINE CELL LEVEL; INFLAMMATION; NONHUMAN; PATHOGENESIS; PROTEIN EXPRESSION; WESTERN BLOTTING; ANIMAL; CELL LINE; CYTOLOGY; DRUG EFFECTS; GENE EXPRESSION REGULATION; INTRACELLULAR SPACE; METABOLISM; MOUSE; PATHOLOGY; SIGNAL TRANSDUCTION;

ADIPOCYTES; ANIMALS; CELL DIFFERENTIATION; CELL LINE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLUTAMATE-AMMONIA LIGASE; GLUTAMINE; INFLAMMATION; INTRACELLULAR SPACE; LIPOPOLYSACCHARIDES; MICE; SIGNAL TRANSDUCTION;

EID: 84915755954     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2014.11.015     Document Type: Article

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