Anticancer profile of a series of gold(III) (2-phenyl)pyridine complexes

ChemMedChem

Volumn 9, Issue 12, 2014, Pages 2781-2790

  Rubbiani, Riccardo ^a   Zehnder, Thomas N ^a   Mari, Cristina ^a   Blacque, Olivier ^a   Venkatesan, Koushik ^a   Gasser, Gilles ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

Antitumor agents; Apoptosis; Gold(III) complexes; Inorganic chemical biology; Medicinal organometallic chemistry; Thioredoxin reductase

Indexed keywords

AURANOFIN; CISPLATIN; GLUTATHIONE REDUCTASE; GOLD DERIVATIVE; GUANOSINE PHOSPHATE; REACTIVE OXYGEN METABOLITE; THIOREDOXIN REDUCTASE; ANTINEOPLASTIC AGENT; COORDINATION COMPOUND; GOLD; PROTEIN BINDING; PYRIDINE; PYRIDINE DERIVATIVE;

ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CANCER CELL; COMPLEX FORMATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG STABILITY; DRUG SYNTHESIS; EC50; ENZYME INHIBITION; HOMEOSTASIS; HUMAN; HUMAN CELL; PROTON NUCLEAR MAGNETIC RESONANCE; X RAY CRYSTALLOGRAPHY; ANTAGONISTS AND INHIBITORS; APOPTOSIS; CHEMISTRY; CONFORMATION; DRUG EFFECTS; HELA CELL LINE; METABOLISM; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; COORDINATION COMPLEXES; CRYSTALLOGRAPHY, X-RAY; DRUG STABILITY; GLUTATHIONE REDUCTASE; GOLD; HELA CELLS; HUMANS; MOLECULAR CONFORMATION; PROTEIN BINDING; PYRIDINES; REACTIVE OXYGEN SPECIES; THIOREDOXIN-DISULFIDE REDUCTASE;

EID: 84915751174     PISSN: 18607179     EISSN: 18607187     Source Type: Journal    
DOI: 10.1002/cmdc.201402446     Document Type: Article

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