Insights on the mechanism of thioredoxin reductase inhibition by Gold N-heterocyclic carbene compounds using the synthetic linear Selenocysteine containing C-terminal peptide hTrxR(488-499): An ESI-MS investigation

Journal of Inorganic Biochemistry

Volumn 136, Issue , 2014, Pages 161-169

  Pratesi, Alessandro ^a   Gabbiani, Chiara ^b   Michelucci, Elena ^a   Ginanneschi, Mauro ^a   Papini, Anna Maria ^a   Rubbiani, Riccardo ^c   Ott, Ingo ^c   Messori, Luigi ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

^b UNIVERSITY OF PISA   (Italy)

^c TECHNICAL UNIVERSITY OF BRAUNSCHWEIG   (Germany)

Author keywords

ESI MS; Gold NHC carbenes; Synthetic peptide; Thioredoxin reductase

Indexed keywords

CARBENE; GOLD; SELENOCYSTEINE; SYNTHETIC PEPTIDE; THIOREDOXIN REDUCTASE; COORDINATION COMPOUND; ENZYME INHIBITOR; GOLD DERIVATIVE; HETEROCYCLIC COMPOUND; OLIGOPEPTIDE;

ARTICLE; CARBOXY TERMINAL SEQUENCE; ELECTROSPRAY MASS SPECTROMETRY; ENZYME INHIBITION; PROTEIN STRUCTURE; AMINO ACID SEQUENCE; ANTAGONISTS AND INHIBITORS; CHEMISTRY;

AMINO ACID SEQUENCE; COORDINATION COMPLEXES; ENZYME INHIBITORS; GOLD COMPOUNDS; HETEROCYCLIC COMPOUNDS; OLIGOPEPTIDES; SELENOCYSTEINE; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; THIOREDOXIN-DISULFIDE REDUCTASE;

EID: 84902341338     PISSN: 01620134     EISSN: 18733344     Source Type: Journal    
DOI: 10.1016/j.jinorgbio.2014.01.009     Document Type: Article

References (22)

1. T. Sandalova, L. Zhong, Y. Lindqvist, A. Holmgren, and G. Schneider Proc. Natl. Acad. Sci. U. S. A. 98 2001 9533 9538
2. E.I. Biterova, A.A. Turanov, V.N. Gladyshev, and J.J. Barycki Proc. Natl. Acad. Sci. U. S. A. 102 2005 15018
3. L. Zhong, and A.J. Holmgren Biol. Chem. 275 2000 18121 18128
4. A. Bindoli, M.P. Rigobello, G. Scutari, C. Gabbiani, A. Casini, and L. Messori Coord. Chem. Rev. 253 2009 1692 1707
5. J. Lu, E.H. Chew, and A. Holmgren Proc. Natl. Acad. Sci. U. S. A. 104 2007 12288 12293
6. Y.C. Lo, T.P. Ko, W.C. Su, T.L. Su, and A.H.J. Wang J. Inorg. Biochem. 103 2009 1082
7. C. Gabbiani, G. Mastrobuoni, F. Sorrentino, B. Dani, M.P. Rigobello, A. Bindoli, M.A. Cinellu, G. Pieraccini, L. Messori, and A. Casini Med. Chem. Commun. 2 2011 50 54
8. Y. Omata, M. Folan, M. Shaw, R.L. Messer, P.E. Lockwood, D. Hobbs, S. Bouillaguet, H. Sano, J.B. Lewis, and J.C. Wataha Toxicol. in Vitro 20 2006 882 890
9. A. Pratesi, C. Gabbiani, M. Ginanneschi, and L. Messori Chem. Commun. 46 2010 7001 7003
10. M.V. Baker, P.J. Barnard, S.J. Berners-Price, S.K. Brayshaw, J.L. Hickey, B.W. Skelton, and A.H. White Dalton Trans. 2006 3708 3715
11. R. Rubbiani, I. Kitanovic, H. Alborzinia, S. Can, A. Kitanovic, L.A. Onambele, M. Stefanopoulou, Y. Geldmacher, W.S. Sheldrick, G. Wolber, A. Prokop, S. Wölfl, and I. Ott J. Med. Chem. 53 2010 8608 8618
12. J.L. Hickey, R.A. Ruhayel, P.J. Barnard, M.V. Baker, S.J. Berners-Price, and A. Filipovska J. Am. Chem. Soc. 130 2008 12570 12571
13. R. Rubbiani, E. Schuh, A. Meyer, J. Lemke, J. Wimberg, N. Metzler-Nolte, F. Meyer, F. Mohr, and I. Ott Med. Chem. Commun. 4 2013 942 948
14. E. Schuh, C. Pflüger, A. Citta, A. Folda, M.P. Rigobello, A. Bindoli, A. Casini, and F. Mohr J. Med. Chem. 55 2012 5518 5528
15. R. Rubbiani, S. Can, I. Kitanovic, H. Alborzinia, M. Stefanopoulou, M. Kokoschka, S. Mönchgesang, W.S. Sheldrick, S. Wölfl, and I. Ott J. Med. Chem. 54 2011 8646 8657
16. W.F. Kean, L. Hart, and W.W. Buchannan Br. J. Rheumatol. 36 1997 560 572
17. D. Besse, and L. Moroder J. Pept. Sci. 3 1997 442 453
18. R.J. Hondal, B.L. Nilsson, and R.T. Raines J. Am. Chem. Soc. 123 2001 5140 5141
19. R.J. Hondal, and R.T. Raines Methods Enzymol. 347 2002 70 83
20. E. Kaiser, R.L. Colescott, C.D. Bossinger, and P.I. Cook Anal. Biochem. 34 1970 595 598
21. K. Harris, S. Flemer Jr., and R.J. Hondal J. Pept. Sci. 13 2007 81 93
22. L. Oehninger, M. Stefanopoulou, H. Alborzinia, J. Schur, S. Ludewig, K. Namikawa, A. Muñoz-Castro, R.W. Köster, K. Baumann, S. Wölfl, W.S. Sheldrick, and I. Ott Dalton Trans. 42 2013 1657 1666