메뉴 건너뛰기




Volumn 16, Issue 7, 2012, Pages 1593-1605

Effects of redox modulation by inhibition of thioredoxin reductase on radiosensitivity and gene expression

Author keywords

Ionizing radiation; Lung cancer; Radiation resistance; Radiosensitizer; Thioredoxin reductase

Indexed keywords

GOLD DERIVATIVE; PHOSPHINE; PHOSPHINE DERIVATIVE; SMALL INTERFERING RNA; THIOREDOXIN REDUCTASE;

EID: 84863100036     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1582-4934.2011.01469.x     Document Type: Article
Times cited : (29)

References (43)
  • 1
    • 0027767943 scopus 로고
    • The biology of radioresistance: similarities, differences and interactions with drug resistance
    • Powell SN, Abraham EH. The biology of radioresistance: similarities, differences and interactions with drug resistance. Cytotechnology. 1993; 12: 325-45.
    • (1993) Cytotechnology , vol.12 , pp. 325-345
    • Powell, S.N.1    Abraham, E.H.2
  • 2
    • 34347240794 scopus 로고    scopus 로고
    • Chemical radiosensitizers for use in radiotherapy
    • Wardman P. Chemical radiosensitizers for use in radiotherapy. Clin Oncol (R Coll Radiol). 2007; 19: 397-417.
    • (2007) Clin Oncol (R Coll Radiol) , vol.19 , pp. 397-417
    • Wardman, P.1
  • 3
    • 39749097912 scopus 로고    scopus 로고
    • Alterations of cellular redox state during NNK-induced malignant transformation and resistance to radiation
    • Demizu Y, Sasaki R, Trachootham D, et al. Alterations of cellular redox state during NNK-induced malignant transformation and resistance to radiation. Antioxid Redox Signal. 2008; 10: 951-61.
    • (2008) Antioxid Redox Signal , vol.10 , pp. 951-961
    • Demizu, Y.1    Sasaki, R.2    Trachootham, D.3
  • 4
    • 64749093574 scopus 로고    scopus 로고
    • Association of reactive oxygen species levels and radioresistance in cancer stem cells
    • Diehn M, Cho RW, Lobo NA, et al. Association of reactive oxygen species levels and radioresistance in cancer stem cells. Nature. 2009; 458: 780-3.
    • (2009) Nature , vol.458 , pp. 780-783
    • Diehn, M.1    Cho, R.W.2    Lobo, N.A.3
  • 5
    • 7944223434 scopus 로고    scopus 로고
    • Increased expression of antioxidant enzymes in radioresistant variant from U251 human glioblastoma cell line
    • Lee HC, Kim DW, Jung KY, et al. Increased expression of antioxidant enzymes in radioresistant variant from U251 human glioblastoma cell line. Int J Mol Med. 2004; 13: 883-7.
    • (2004) Int J Mol Med , vol.13 , pp. 883-887
    • Lee, H.C.1    Kim, D.W.2    Jung, K.Y.3
  • 6
    • 0030754701 scopus 로고    scopus 로고
    • Resistance to radiation-induced apoptosis in Bcl-2-expressing cells is reversed by depleting cellular thiols
    • Mirkovic N, Voehringer DW, Story MD, et al. Resistance to radiation-induced apoptosis in Bcl-2-expressing cells is reversed by depleting cellular thiols. Oncogene. 1997; 15: 1461-70.
    • (1997) Oncogene , vol.15 , pp. 1461-1470
    • Mirkovic, N.1    Voehringer, D.W.2    Story, M.D.3
  • 7
    • 0032030989 scopus 로고    scopus 로고
    • Role of antioxidant enzymes on ionizing radiation resistance
    • Sun J, Chen Y, Li M, et al. Role of antioxidant enzymes on ionizing radiation resistance. Free Radic Biol Med. 1998; 24: 586-93.
    • (1998) Free Radic Biol Med , vol.24 , pp. 586-593
    • Sun, J.1    Chen, Y.2    Li, M.3
  • 8
    • 0037384491 scopus 로고    scopus 로고
    • Radiation response of cells during altered protein thiol redox
    • Biaglow JE, Ayene IS, Koch CJ, et al. Radiation response of cells during altered protein thiol redox. Radiat Res. 2003; 159: 484-94.
    • (2003) Radiat Res , vol.159 , pp. 484-494
    • Biaglow, J.E.1    Ayene, I.S.2    Koch, C.J.3
  • 9
    • 10344234178 scopus 로고    scopus 로고
    • Redox modulation of human prostate carcinoma cells by selenite increases radiation-induced cell killing
    • Husbeck B, Peehl DM, Knox SJ. Redox modulation of human prostate carcinoma cells by selenite increases radiation-induced cell killing. Free Radic Biol Med. 2005; 38: 50-7.
    • (2005) Free Radic Biol Med , vol.38 , pp. 50-57
    • Husbeck, B.1    Peehl, D.M.2    Knox, S.J.3
  • 10
    • 0037068769 scopus 로고    scopus 로고
    • Thioredoxin reductase regulates AP-1 activity as well as thioredoxin nuclear localization via active cysteines in response to ionizing radiation
    • Karimpour S, Lou J, Lin LL, et al. Thioredoxin reductase regulates AP-1 activity as well as thioredoxin nuclear localization via active cysteines in response to ionizing radiation. Oncogene. 2002; 21: 6317-27.
    • (2002) Oncogene , vol.21 , pp. 6317-6327
    • Karimpour, S.1    Lou, J.2    Lin, L.L.3
  • 11
    • 0034544555 scopus 로고    scopus 로고
    • Thioredoxin nuclear translocation and interaction with redox factor-1 activates the activator protein-1 transcription factor in response to ionizing radiation
    • Wei SJ, Botero A, Hirota K, et al. Thioredoxin nuclear translocation and interaction with redox factor-1 activates the activator protein-1 transcription factor in response to ionizing radiation. Cancer Res. 2000; 60: 6688-95.
    • (2000) Cancer Res , vol.60 , pp. 6688-6695
    • Wei, S.J.1    Botero, A.2    Hirota, K.3
  • 12
    • 0033775891 scopus 로고    scopus 로고
    • Physiological functions of thioredoxin and thioredoxin reductase
    • Arner ES, Holmgren A. Physiological functions of thioredoxin and thioredoxin reductase. Eur J Biochem. 2000; 267: 6102-9.
    • (2000) Eur J Biochem , vol.267 , pp. 6102-6109
    • Arner, E.S.1    Holmgren, A.2
  • 13
    • 0242277285 scopus 로고    scopus 로고
    • The thioredoxin system-from science to clinic
    • Gromer S, Urig S, Becker K. The thioredoxin system-from science to clinic. Med Res Rev. 2004; 24: 40-89.
    • (2004) Med Res Rev , vol.24 , pp. 40-89
    • Gromer, S.1    Urig, S.2    Becker, K.3
  • 15
    • 15044349930 scopus 로고    scopus 로고
    • Effect of metal complexes on thioredoxin reductase and the regulation of mitochondrial permeability conditions
    • Bragadin M, Scutari G, Folda A, et al. Effect of metal complexes on thioredoxin reductase and the regulation of mitochondrial permeability conditions. Ann N Y Acad Sci. 2004; 1030: 348-54.
    • (2004) Ann N Y Acad Sci , vol.1030 , pp. 348-354
    • Bragadin, M.1    Scutari, G.2    Folda, A.3
  • 16
    • 33745221410 scopus 로고    scopus 로고
    • Sublethal concentrations of diverse gold compounds inhibit mammalian cytosolic thioredoxin reductase (TrxR1)
    • Omata Y, Folan M, Shaw M, et al. Sublethal concentrations of diverse gold compounds inhibit mammalian cytosolic thioredoxin reductase (TrxR1). Toxicol In Vitro. 2006; 20: 882-90.
    • (2006) Toxicol In Vitro , vol.20 , pp. 882-890
    • Omata, Y.1    Folan, M.2    Shaw, M.3
  • 17
    • 5344266051 scopus 로고    scopus 로고
    • Gold complexes inhibit mitochondrial thioredoxin reductase: consequences on mitochondrial functions
    • Rigobello M, Messori L, Marcon G, et al. Gold complexes inhibit mitochondrial thioredoxin reductase: consequences on mitochondrial functions. J Inorg Biochem. 2004; 98: 1634-41.
    • (2004) J Inorg Biochem , vol.98 , pp. 1634-1641
    • Rigobello, M.1    Messori, L.2    Marcon, G.3
  • 18
    • 22044444840 scopus 로고    scopus 로고
    • Effect of auranofin on the mitochondrial generation of hydrogen peroxide. Role of thioredoxin reductase
    • Rigobello MP, Folda A, Baldoin MC, et al. Effect of auranofin on the mitochondrial generation of hydrogen peroxide. Role of thioredoxin reductase. Free Radic Res. 2005; 39: 687-95.
    • (2005) Free Radic Res , vol.39 , pp. 687-695
    • Rigobello, M.P.1    Folda, A.2    Baldoin, M.C.3
  • 19
    • 1642452655 scopus 로고    scopus 로고
    • Mitochondrial thioredoxin reductase inhibition by gold(I) compounds and concurrent stimulation of permeability transition and release of cytochrome c
    • Rigobello MP, Scutari G, Folda A, et al. Mitochondrial thioredoxin reductase inhibition by gold(I) compounds and concurrent stimulation of permeability transition and release of cytochrome c. Biochem Pharmacol. 2004; 67: 689-96.
    • (2004) Biochem Pharmacol , vol.67 , pp. 689-696
    • Rigobello, M.P.1    Scutari, G.2    Folda, A.3
  • 20
    • 33847014053 scopus 로고    scopus 로고
    • Inhibition of thioredoxin reductase by auranofin induces apoptosis in cisplatin-resistant human ovarian cancer cells
    • Marzano C, Gandin V, Folda A, et al. Inhibition of thioredoxin reductase by auranofin induces apoptosis in cisplatin-resistant human ovarian cancer cells. Free Radic Biol Med. 2007; 42: 872-81.
    • (2007) Free Radic Biol Med , vol.42 , pp. 872-881
    • Marzano, C.1    Gandin, V.2    Folda, A.3
  • 21
    • 1542426626 scopus 로고    scopus 로고
    • Curcumin confers radiosensitizing effect in prostate cancer cell line PC-3
    • Chendil D, Ranga RS, Meigooni D, et al. Curcumin confers radiosensitizing effect in prostate cancer cell line PC-3. Oncogene. 2004; 23: 1599-607.
    • (2004) Oncogene , vol.23 , pp. 1599-1607
    • Chendil, D.1    Ranga, R.S.2    Meigooni, D.3
  • 22
    • 33751182576 scopus 로고    scopus 로고
    • Protective effect of curcumin on gamma-radiation induced DNA damage and lipid peroxidation in cultured human lymphocytes
    • Srinivasan M, Rajendra Prasad N, Menon VP. Protective effect of curcumin on gamma-radiation induced DNA damage and lipid peroxidation in cultured human lymphocytes. Mutat Res. 2006; 611: 96-103.
    • (2006) Mutat Res , vol.611 , pp. 96-103
    • Srinivasan, M.1    Rajendra Prasad, N.2    Menon, V.P.3
  • 23
    • 71749083138 scopus 로고    scopus 로고
    • Cancer cell death induced by phosphine gold(I) compounds targeting thioredoxin reductase
    • Gandin V, Fernandes AP, Rigobello MP, et al. Cancer cell death induced by phosphine gold(I) compounds targeting thioredoxin reductase. Biochem Pharmacol. 79: 90-101.
    • Biochem Pharmacol , vol.79 , pp. 90-101
    • Gandin, V.1    Fernandes, A.P.2    Rigobello, M.P.3
  • 24
    • 34548276529 scopus 로고    scopus 로고
    • The DNA base excision repair protein Ape1/Ref-1 as a therapeutic and chemopreventive target
    • Fishel ML, Kelley MR. The DNA base excision repair protein Ape1/Ref-1 as a therapeutic and chemopreventive target. Mol Aspects Med. 2007; 28: 375-95.
    • (2007) Mol Aspects Med , vol.28 , pp. 375-395
    • Fishel, M.L.1    Kelley, M.R.2
  • 25
    • 0030936568 scopus 로고    scopus 로고
    • AP-1 transcriptional activity is regulated by a direct association between thioredoxin and Ref-1
    • Hirota K, Matsui M, Iwata S, et al. AP-1 transcriptional activity is regulated by a direct association between thioredoxin and Ref-1. Proc Natl Acad Sci USA. 1997; 94: 3633-8.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 3633-3638
    • Hirota, K.1    Matsui, M.2    Iwata, S.3
  • 27
    • 0026323150 scopus 로고
    • Single-dose and fractionated irradiation of four human lung cancer cell lines in vitro
    • Brodin O, Lennartsson L, Nilsson S. Single-dose and fractionated irradiation of four human lung cancer cell lines in vitro. Acta Oncol. 1991; 30: 967-74.
    • (1991) Acta Oncol , vol.30 , pp. 967-974
    • Brodin, O.1    Lennartsson, L.2    Nilsson, S.3
  • 28
    • 0029311273 scopus 로고
    • Increased radioresistance of an in vitro transformed human small cell lung cancer cell line
    • Brodin O, Arnberg H, Bergh J, et al. Increased radioresistance of an in vitro transformed human small cell lung cancer cell line. Lung Cancer. 1995; 12: 183-98.
    • (1995) Lung Cancer , vol.12 , pp. 183-198
    • Brodin, O.1    Arnberg, H.2    Bergh, J.3
  • 29
    • 0019458005 scopus 로고
    • Radiation effects on cultured human lymphoid cells. Analysis using the growth extrapolation method
    • Johansson L, Nilsson K, Carlsson J, et al. Radiation effects on cultured human lymphoid cells. Analysis using the growth extrapolation method. Acta Radiol Oncol. 1981; 20: 51-9.
    • (1981) Acta Radiol Oncol , vol.20 , pp. 51-59
    • Johansson, L.1    Nilsson, K.2    Carlsson, J.3
  • 30
    • 0029187491 scopus 로고
    • Thioredoxin and thioredoxin reductase
    • Holmgren A, Bjornstedt M. Thioredoxin and thioredoxin reductase. Methods Enzymol. 1995; 252: 199-208.
    • (1995) Methods Enzymol , vol.252 , pp. 199-208
    • Holmgren, A.1    Bjornstedt, M.2
  • 31
    • 33846952526 scopus 로고    scopus 로고
    • Quantification of alternative mRNA species and identification of thioredoxin reductase 1 isoforms in human tumour cells
    • Rundlof AK, Fernandes AP, Selenius M, et al. Quantification of alternative mRNA species and identification of thioredoxin reductase 1 isoforms in human tumour cells. Differentiation. 2007; 75: 123-32.
    • (2007) Differentiation , vol.75 , pp. 123-132
    • Rundlof, A.K.1    Fernandes, A.P.2    Selenius, M.3
  • 32
    • 0035808392 scopus 로고    scopus 로고
    • Eosinophil peroxidase oxidation of thiocyanate. Characterization of major reaction products and a potential sulfhydryl-targeted cytotoxicity system
    • Arlandson M, Decker T, Roongta VA, et al. Eosinophil peroxidase oxidation of thiocyanate. Characterization of major reaction products and a potential sulfhydryl-targeted cytotoxicity system. J Biol Chem. 2001; 276: 215-24.
    • (2001) J Biol Chem , vol.276 , pp. 215-224
    • Arlandson, M.1    Decker, T.2    Roongta, V.A.3
  • 34
    • 0141673128 scopus 로고    scopus 로고
    • Biological chemistry of reactive oxygen and nitrogen and radiation-induced signal transduction mechanisms
    • Mikkelsen RB, Wardman P. Biological chemistry of reactive oxygen and nitrogen and radiation-induced signal transduction mechanisms. Oncogene. 2003; 22: 5734-54.
    • (2003) Oncogene , vol.22 , pp. 5734-5754
    • Mikkelsen, R.B.1    Wardman, P.2
  • 35
    • 3042661957 scopus 로고    scopus 로고
    • Role of cell cycle in mediating sensitivity to radiotherapy
    • Pawlik TM, Keyomarsi K. Role of cell cycle in mediating sensitivity to radiotherapy. Int J Radiat Oncol Biol Phys. 2004; 59: 928-42.
    • (2004) Int J Radiat Oncol Biol Phys , vol.59 , pp. 928-942
    • Pawlik, T.M.1    Keyomarsi, K.2
  • 36
    • 0030775165 scopus 로고    scopus 로고
    • Characterisation of the G1/S cell cycle checkpoint defect in lung carcinoma cells with different intrinsic radiosensitivities
    • Sirzen F, Heiden T, Nilsson A, et al. Characterisation of the G1/S cell cycle checkpoint defect in lung carcinoma cells with different intrinsic radiosensitivities. Anticancer Res. 1997; 17: 3381-6.
    • (1997) Anticancer Res , vol.17 , pp. 3381-3386
    • Sirzen, F.1    Heiden, T.2    Nilsson, A.3
  • 37
    • 39749177838 scopus 로고    scopus 로고
    • Targeting thioredoxin reductase 1 reduction in cancer cells inhibits self-sufficient growth and DNA replication
    • Yoo MH, Xu XM, Carlson BA, et al. Targeting thioredoxin reductase 1 reduction in cancer cells inhibits self-sufficient growth and DNA replication. PLoS One. 2007; 2: e1112.
    • (2007) PLoS One , vol.2
    • Yoo, M.H.1    Xu, X.M.2    Carlson, B.A.3
  • 38
    • 27144473412 scopus 로고    scopus 로고
    • Inhibitory effects of thioredoxin reductase antisense RNA on the growth of human hepatocellular carcinoma cells
    • Gan L, Yang XL, Liu Q, et al. Inhibitory effects of thioredoxin reductase antisense RNA on the growth of human hepatocellular carcinoma cells. J Cell Biochem. 2005; 96: 653-64.
    • (2005) J Cell Biochem , vol.96 , pp. 653-664
    • Gan, L.1    Yang, X.L.2    Liu, Q.3
  • 39
    • 0025029088 scopus 로고
    • DNA damage and repair following treatment with ionizing radiation
    • Powell S, McMillan TJ. DNA damage and repair following treatment with ionizing radiation. Radiother Oncol. 1990; 19: 95-108.
    • (1990) Radiother Oncol , vol.19 , pp. 95-108
    • Powell, S.1    McMillan, T.J.2
  • 40
    • 0032945675 scopus 로고    scopus 로고
    • Induction of cell death by radiotherapy
    • Ross GM. Induction of cell death by radiotherapy. Endocr Relat Cancer. 1999; 6: 41-4.
    • (1999) Endocr Relat Cancer , vol.6 , pp. 41-44
    • Ross, G.M.1
  • 42
    • 0033532619 scopus 로고    scopus 로고
    • Thioredoxin, a redox enzyme released in infection and inflammation, is a unique chemoattractant for neutrophils, monocytes, and T cells
    • Bertini R, Howard OM, Dong HF, et al. Thioredoxin, a redox enzyme released in infection and inflammation, is a unique chemoattractant for neutrophils, monocytes, and T cells. J Exp Med. 1999; 189: 1783-9.
    • (1999) J Exp Med , vol.189 , pp. 1783-1789
    • Bertini, R.1    Howard, O.M.2    Dong, H.F.3
  • 43
    • 0037468629 scopus 로고    scopus 로고
    • Truncated thioredoxin (Trx80) exerts unique mitogenic cytokine effects via a mechanism independent of thiol oxido-reductase activity
    • Pekkari K, Avila-Carino J, Gurunath R, et al. Truncated thioredoxin (Trx80) exerts unique mitogenic cytokine effects via a mechanism independent of thiol oxido-reductase activity. FEBS Lett. 2003; 539: 143-8.
    • (2003) FEBS Lett , vol.539 , pp. 143-148
    • Pekkari, K.1    Avila-Carino, J.2    Gurunath, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.