Inhibition of tumor cell proliferation and motility by fibroblasts is both contact and soluble factor dependent

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 48, 2014, Pages 17188-17193

  Alkasaliasa, Twana ^a,b   Flaberg, Emilie ^a   Kashuba, Vladimir ^a,c   Alexeyenko, Andrey ^a,d   Pavlova, Tatiana ^a   Savchenko, Andrii ^a   Szekely, Laszlo ^a   Klein, George ^a   Guvena, Hayrettin ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b SALAHADDIN UNIVERSITY   (Iraq)

^c INSTITUTE OF MOLECULAR BIOLOGY AND GENETICS   (Ukraine)

^d SCIENCE FOR LIFE LABORATORY   (Sweden)

Author keywords

Cancer associated fibroblast |; Extracellular matrix |; Motility |; Soluble factors; Tumor microenvironment |

Indexed keywords

COLLAGEN TYPE 15; COLLAGEN TYPE 15A; CXCL1 CHEMOKINE; CXCL2 CHEMOKINE; DICKKOPF 1 PROTEIN; ENDOTHELIAL MONOCYTE ACTIVATING POLYPEPTIDE II; ENTACTIN; GALECTIN 3; GROWTH DIFFERENTIATION FACTOR 15; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; MEMBRANE PROTEIN; NIDOGEN 1; STROMELYSIN; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 1; UNCLASSIFIED DRUG; UROKINASE; CULTURE MEDIUM; PHOTOPROTEIN; RED FLUORESCENT PROTEIN;

ARTICLE; CANCER INHIBITION; CELL GROWTH; CELL MOTILITY; CELL MOTION; CELL PROLIFERATION; CELLULAR SECRETION; CONTROLLED STUDY; DOWN REGULATION; EXTRACELLULAR MATRIX; FIBROBLAST; GENE IDENTIFICATION; HUMAN; HUMAN CELL; POLYMERASE CHAIN REACTION; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; TUMOR CELL; TUMOR GROWTH; UPREGULATION; ANIMAL; CELL CULTURE; CELL LINE; CHEMISTRY; COCULTURE; CONTACT INHIBITION; CULTURE MEDIUM; CYTOLOGY; DNA MICROARRAY; DRUG EFFECTS; FLUORESCENCE MICROSCOPY; GENE EXPRESSION PROFILING; GENETICS; METABOLISM; MOUSE; PHARMACOLOGY; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL LINE;

MURINAE;

ANIMALS; CELL LINE; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; COCULTURE TECHNIQUES; CONTACT INHIBITION; CULTURE MEDIA, CONDITIONED; EXTRACELLULAR MATRIX; FIBROBLASTS; GENE EXPRESSION PROFILING; HUMANS; LUMINESCENT PROTEINS; MICE; MICROSCOPY, FLUORESCENCE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 84914703771     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1419554111     Document Type: Article

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