-
1
-
-
34548638261
-
Structure and mechanism of helicases and nucleic acid translocases
-
Singleton MR, Dillingham MS, Wigley DB, (2007) Structure and mechanism of helicases and nucleic acid translocases. Ann Rev Biochem 76: 23-50.
-
(2007)
Ann Rev Biochem
, vol.76
, pp. 23-50
-
-
Singleton, M.R.1
Dillingham, M.S.2
Wigley, D.B.3
-
2
-
-
7044246179
-
RecA-like motor ATPases - Lessons from structures
-
Ye J, Osborne AR, Groll M, Rapoport TA, (2004) RecA-like motor ATPases-lessons from structures. Biochim Biophys Acta 1659: 1-18.
-
(2004)
Biochim Biophys Acta
, vol.1659
, pp. 1-18
-
-
Ye, J.1
Osborne, A.R.2
Groll, M.3
Rapoport, T.A.4
-
3
-
-
0001607723
-
Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold
-
Walker JE, Saraste M, Runswick MJ, Gay NJ, (1982) Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold. EMBO J 1: 945-951.
-
(1982)
EMBO J
, vol.1
, pp. 945-951
-
-
Walker, J.E.1
Saraste, M.2
Runswick, M.J.3
Gay, N.J.4
-
4
-
-
0027182114
-
Helicases - Amino-acid-sequence comparisons and structure-function-relationships
-
Gorbalenya AE, Koonin EV, (1993) Helicases-amino-acid-sequence comparisons and structure-function-relationships. Curr Opin Struct Biol 3: 419-429.
-
(1993)
Curr Opin Struct Biol
, vol.3
, pp. 419-429
-
-
Gorbalenya, A.E.1
Koonin, E.V.2
-
5
-
-
84873653618
-
Overview: What are helicases?
-
Wu CG, Spies M, (2013) Overview: what are helicases? Adv Exp Med Biol 767: 1-16.
-
(2013)
Adv Exp Med Biol
, vol.767
, pp. 1-16
-
-
Wu, C.G.1
Spies, M.2
-
8
-
-
0017113549
-
Enzymic unwinding of DNA. 2. Chain separation by an ATP-dependent DNA unwinding enzyme
-
Abdel-Monem M, Durwald H, Hoffmann-Berling H, (1976) Enzymic unwinding of DNA. 2. Chain separation by an ATP-dependent DNA unwinding enzyme. Eur J Biochem/FEBS 65: 441-449.
-
(1976)
Eur J Biochem/FEBS
, vol.65
, pp. 441-449
-
-
Abdel-Monem, M.1
Durwald, H.2
Hoffmann-Berling, H.3
-
10
-
-
0033515425
-
Crystal structures of complexes of PcrA DNA helicase with a DNA substrate indicate an inchworm mechanism
-
Velankar SS, Soultanas P, Dillingham MS, Subramanya HS, Wigley DB, (1999) Crystal structures of complexes of PcrA DNA helicase with a DNA substrate indicate an inchworm mechanism. Cell 97: 75-84.
-
(1999)
Cell
, vol.97
, pp. 75-84
-
-
Velankar, S.S.1
Soultanas, P.2
Dillingham, M.S.3
Subramanya, H.S.4
Wigley, D.B.5
-
11
-
-
84900459777
-
Structure of human Bloom's syndrome helicase in complex with ADP and duplex DNA
-
Swan MK, Legris V, Tanner A, Reaper PM, Vial S, Bordas R, Pollard JR, Charlton PA, Golec JM, Bertrand JA, (2014) Structure of human Bloom's syndrome helicase in complex with ADP and duplex DNA. Acta Cryst D70: 1465-1475.
-
(2014)
Acta Cryst
, vol.D70
, pp. 1465-1475
-
-
Swan, M.K.1
Legris, V.2
Tanner, A.3
Reaper, P.M.4
Vial, S.5
Bordas, R.6
Pollard, J.R.7
Charlton, P.A.8
Golec, J.M.9
Bertrand, J.A.10
-
12
-
-
0029856618
-
Crystal structure of a DExx box DNA helicase
-
Subramanya HS, Bird LE, Brannigan JA, Wigley DB, (1996) Crystal structure of a DExx box DNA helicase. Nature 384: 379-383.
-
(1996)
Nature
, vol.384
, pp. 379-383
-
-
Subramanya, H.S.1
Bird, L.E.2
Brannigan, J.A.3
Wigley, D.B.4
-
13
-
-
0026680746
-
Mutational analysis of a DEAD box RNA helicase: The mammalian translation initiation factor eIF-4A
-
Pause A, Sonenberg N, (1992) Mutational analysis of a DEAD box RNA helicase: the mammalian translation initiation factor eIF-4A. EMBO J 11: 2643-2654.
-
(1992)
EMBO J
, vol.11
, pp. 2643-2654
-
-
Pause, A.1
Sonenberg, N.2
-
14
-
-
0037252143
-
The Q motif: A newly identified motif in DEAD box helicases may regulate ATP binding and hydrolysis
-
Tanner NK, Cordin O, Banroques J, Doere M, Linder P, (2003) The Q motif: a newly identified motif in DEAD box helicases may regulate ATP binding and hydrolysis. Mol Cell 11: 127-138.
-
(2003)
Mol Cell
, vol.11
, pp. 127-138
-
-
Tanner, N.K.1
Cordin, O.2
Banroques, J.3
Doere, M.4
Linder, P.5
-
15
-
-
0031911760
-
Comparisons between the structures of HCV and Rep helicases reveal structural similarities between SF1 and SF2 super-families of helicases
-
Korolev S, Yao N, Lohman TM, Weber PC, Waksman G, (1998) Comparisons between the structures of HCV and Rep helicases reveal structural similarities between SF1 and SF2 super-families of helicases. Protein Sci 7: 605-610.
-
(1998)
Protein Sci
, vol.7
, pp. 605-610
-
-
Korolev, S.1
Yao, N.2
Lohman, T.M.3
Weber, P.C.4
Waksman, G.5
-
16
-
-
0037415719
-
A model for dsDNA translocation revealed by a structural motif common to RecG and Mfd proteins
-
Mahdi AA, Briggs GS, Sharples GJ, Wen Q, Lloyd RG, (2003) A model for dsDNA translocation revealed by a structural motif common to RecG and Mfd proteins. EMBO J 22: 724-734.
-
(2003)
EMBO J
, vol.22
, pp. 724-734
-
-
Mahdi, A.A.1
Briggs, G.S.2
Sharples, G.J.3
Wen, Q.4
Lloyd, R.G.5
-
17
-
-
33845657428
-
UvrD helicase unwinds DNA one base pair at a time by a two-part power stroke
-
Lee JY, Yang W, (2006) UvrD helicase unwinds DNA one base pair at a time by a two-part power stroke. Cell 127: 1349-1360.
-
(2006)
Cell
, vol.127
, pp. 1349-1360
-
-
Lee, J.Y.1
Yang, W.2
-
18
-
-
84885442820
-
Structural and mechanistic insight into DNA unwinding by Deinococcus radiodurans UvrD
-
Stelter M, Acajjaoui S, McSweeney S, Timmins J, (2013) Structural and mechanistic insight into DNA unwinding by Deinococcus radiodurans UvrD. PloS One 8: e77364.
-
(2013)
PloS One
, vol.8
, pp. e77364
-
-
Stelter, M.1
Acajjaoui, S.2
McSweeney, S.3
Timmins, J.4
-
19
-
-
9144271294
-
Crystal structure of RecBCD enzyme reveals a machine for processing DNA breaks
-
Singleton MR, Dillingham MS, Gaudier M, Kowalczykowski SC, Wigley DB, (2004) Crystal structure of RecBCD enzyme reveals a machine for processing DNA breaks. Nature 432: 187-193.
-
(2004)
Nature
, vol.432
, pp. 187-193
-
-
Singleton, M.R.1
Dillingham, M.S.2
Gaudier, M.3
Kowalczykowski, S.C.4
Wigley, D.B.5
-
20
-
-
84858796420
-
Insights into Chi recognition from the structure of an AddAB-type helicase-nuclease complex
-
Saikrishnan K, Yeeles JT, Gilhooly NS, Krajewski WW, Dillingham MS, Wigley DB, (2012) Insights into Chi recognition from the structure of an AddAB-type helicase-nuclease complex. EMBO J 31: 1568-1578.
-
(2012)
EMBO J
, vol.31
, pp. 1568-1578
-
-
Saikrishnan, K.1
Yeeles, J.T.2
Gilhooly, N.S.3
Krajewski, W.W.4
Dillingham, M.S.5
Wigley, D.B.6
-
21
-
-
84898995018
-
Structural basis for translocation by AddAB helicase-nuclease and its arrest at chi sites
-
Krajewski WW, Fu X, Wilkinson M, Cronin NB, Dillingham MS, Wigley DB, (2014) Structural basis for translocation by AddAB helicase-nuclease and its arrest at chi sites. Nature 508: 416-419.
-
(2014)
Nature
, vol.508
, pp. 416-419
-
-
Krajewski, W.W.1
Fu, X.2
Wilkinson, M.3
Cronin, N.B.4
Dillingham, M.S.5
Wigley, D.B.6
-
22
-
-
34447132375
-
Structural basis for DNA duplex separation by a superfamily-2 helicase
-
Buttner K, Nehring S, Hopfner KP, (2007) Structural basis for DNA duplex separation by a superfamily-2 helicase. Nat Struct Mol Biol 14: 647-652.
-
(2007)
Nat Struct Mol Biol
, vol.14
, pp. 647-652
-
-
Buttner, K.1
Nehring, S.2
Hopfner, K.P.3
-
23
-
-
41949094586
-
Structure of the DNA repair helicase hel308 reveals DNA binding and autoinhibitory domains
-
Richards JD, Johnson KA, Liu H, McRobbie AM, McMahon S, Oke M, Carter L, Naismith JH, White MF, (2008) Structure of the DNA repair helicase hel308 reveals DNA binding and autoinhibitory domains. J Biol Chem 283: 5118-5126.
-
(2008)
J Biol Chem
, vol.283
, pp. 5118-5126
-
-
Richards, J.D.1
Johnson, K.A.2
Liu, H.3
McRobbie, A.M.4
McMahon, S.5
Oke, M.6
Carter, L.7
Naismith, J.H.8
White, M.F.9
-
24
-
-
0033527761
-
An oligomeric form of E. Coli UvrD is required for optimal helicase activity
-
Ali JA, Maluf NK, Lohman TM, (1999) An oligomeric form of E. coli UvrD is required for optimal helicase activity. J Mol Biol 293: 815-834.
-
(1999)
J Mol Biol
, vol.293
, pp. 815-834
-
-
Ali, J.A.1
Maluf, N.K.2
Lohman, T.M.3
-
25
-
-
2542432027
-
Protein displacement by an assembly of helicase molecules aligned along single-stranded DNA
-
Byrd AK, Raney KD, (2004) Protein displacement by an assembly of helicase molecules aligned along single-stranded DNA. Nat Struct Mol Biol 11: 531-538.
-
(2004)
Nat Struct Mol Biol
, vol.11
, pp. 531-538
-
-
Byrd, A.K.1
Raney, K.D.2
-
26
-
-
25444456899
-
Increasing the length of the single-stranded overhang enhances unwinding of duplex DNA by bacteriophage T4 Dda helicase
-
Byrd AK, Raney KD, (2005) Increasing the length of the single-stranded overhang enhances unwinding of duplex DNA by bacteriophage T4 Dda helicase. Biochemistry 44: 12990-12997.
-
(2005)
Biochemistry
, vol.44
, pp. 12990-12997
-
-
Byrd, A.K.1
Raney, K.D.2
-
27
-
-
79960907291
-
Rotations of the 2B sub-domain of E. Coli UvrD helicase/translocase coupled to nucleotide and DNA binding
-
Jia H, Korolev S, Niedziela-Majka A, Maluf NK, Gauss GH, Myong S, Ha T, Waksman G, Lohman TM, (2011) Rotations of the 2B sub-domain of E. coli UvrD helicase/translocase coupled to nucleotide and DNA binding. J Mol Biol 411: 633-648.
-
(2011)
J Mol Biol
, vol.411
, pp. 633-648
-
-
Jia, H.1
Korolev, S.2
Niedziela-Majka, A.3
Maluf, N.K.4
Gauss, G.H.5
Myong, S.6
Ha, T.7
Waksman, G.8
Lohman, T.M.9
-
28
-
-
0037474547
-
A dimer of Escherichia coli UvrD is the active form of the helicase in vitro
-
Maluf NK, Fischer CJ, Lohman TM, (2003) A dimer of Escherichia coli UvrD is the active form of the helicase in vitro. J Mol Biol 325: 913-935.
-
(2003)
J Mol Biol
, vol.325
, pp. 913-935
-
-
Maluf, N.K.1
Fischer, C.J.2
Lohman, T.M.3
-
29
-
-
22544482026
-
Autoinhibition of Escherichia coli Rep monomer helicase activity by its 2B subdomain
-
Brendza KM, Cheng W, Fischer CJ, Chesnik MA, Niedziela-Majka A, Lohman TM, (2005) Autoinhibition of Escherichia coli Rep monomer helicase activity by its 2B subdomain. Proc Natl Acad Sci USA 102: 10076-10081.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 10076-10081
-
-
Brendza, K.M.1
Cheng, W.2
Fischer, C.J.3
Chesnik, M.A.4
Niedziela-Majka, A.5
Lohman, T.M.6
-
30
-
-
79953158070
-
A prominent beta-hairpin structure in the winged-helix domain of RECQ1 is required for DNA unwinding and oligomer formation
-
Lucic B, Zhang Y, King O, Mendoza-Maldonado R, Berti M, Niesen FH, Burgess-Brown NA, Pike AC, Cooper CD, Gileadi O, Vindigni A, (2011) A prominent beta-hairpin structure in the winged-helix domain of RECQ1 is required for DNA unwinding and oligomer formation. Nucleic Acids Res 39: 1703-1717.
-
(2011)
Nucleic Acids Res
, vol.39
, pp. 1703-1717
-
-
Lucic, B.1
Zhang, Y.2
King, O.3
Mendoza-Maldonado, R.4
Berti, M.5
Niesen, F.H.6
Burgess-Brown, N.A.7
Pike, A.C.8
Cooper, C.D.9
Gileadi, O.10
Vindigni, A.11
-
31
-
-
54049147388
-
The Werner syndrome protein binds replication fork and holliday junction DNAs as an oligomer
-
Compton SA, Tolun G, Kamath-Loeb AS, Loeb LA, Griffith JD, (2008) The Werner syndrome protein binds replication fork and holliday junction DNAs as an oligomer. J Biol Chem 283: 24478-24483.
-
(2008)
J Biol Chem
, vol.283
, pp. 24478-24483
-
-
Compton, S.A.1
Tolun, G.2
Kamath-Loeb, A.S.3
Loeb, L.A.4
Griffith, J.D.5
-
32
-
-
0030740262
-
Major domain swiveling revealed by the crystal structures of complexes of E. Coli Rep helicase bound to single-stranded DNA and ADP
-
Korolev S, Hsieh J, Gauss GH, Lohman TM, Waksman G, (1997) Major domain swiveling revealed by the crystal structures of complexes of E. coli Rep helicase bound to single-stranded DNA and ADP. Cell 90: 635-647.
-
(1997)
Cell
, vol.90
, pp. 635-647
-
-
Korolev, S.1
Hsieh, J.2
Gauss, G.H.3
Lohman, T.M.4
Waksman, G.5
-
33
-
-
66149148295
-
Mechanistic basis of 5′-3′ translocation in SF1B helicases
-
Saikrishnan K, Powell B, Cook NJ, Webb MR, Wigley DB, (2009) Mechanistic basis of 5′-3′ translocation in SF1B helicases. Cell 137: 849-859.
-
(2009)
Cell
, vol.137
, pp. 849-859
-
-
Saikrishnan, K.1
Powell, B.2
Cook, N.J.3
Webb, M.R.4
Wigley, D.B.5
-
34
-
-
84863504414
-
The T4 phage SF1B helicase Dda is structurally optimized to perform DNA strand separation
-
He X, Byrd AK, Yun MK, Pemble CWT, Harrison D, Yeruva L, Dahl C, Kreuzer KN, Raney KD, White SW, (2012) The T4 phage SF1B helicase Dda is structurally optimized to perform DNA strand separation. Structure 20: 1189-1200.
-
(2012)
Structure
, vol.20
, pp. 1189-1200
-
-
He, X.1
Byrd, A.K.2
Yun, M.K.3
Pemble, C.W.T.4
Harrison, D.5
Yeruva, L.6
Dahl, C.7
Kreuzer, K.N.8
Raney, K.D.9
White, S.W.10
-
35
-
-
43949110271
-
Structure of the DNA repair helicase XPD
-
Liu H, Rudolf J, Johnson KA, McMahon SA, Oke M, Carter L, McRobbie AM, Brown SE, Naismith JH, White MF, (2008) Structure of the DNA repair helicase XPD. Cell 133: 801-812.
-
(2008)
Cell
, vol.133
, pp. 801-812
-
-
Liu, H.1
Rudolf, J.2
Johnson, K.A.3
McMahon, S.A.4
Oke, M.5
Carter, L.6
McRobbie, A.M.7
Brown, S.E.8
Naismith, J.H.9
White, M.F.10
-
36
-
-
45849119445
-
Crystal structure of the FeS cluster-containing nucleotide excision repair helicase XPD
-
Wolski SC, Kuper J, Hanzelmann P, Truglio JJ, Croteau DL, Van Houten B, Kisker C, (2008) Crystal structure of the FeS cluster-containing nucleotide excision repair helicase XPD. PLoS Biol 6: e149.
-
(2008)
PLoS Biol
, vol.6
, pp. e149
-
-
Wolski, S.C.1
Kuper, J.2
Hanzelmann, P.3
Truglio, J.J.4
Croteau, D.L.5
Van Houten, B.6
Kisker, C.7
-
37
-
-
44149094083
-
XPD helicase structures and activities: Insights into the cancer and aging phenotypes from XPD mutations
-
Fan L, Fuss JO, Cheng QJ, Arvai AS, Hammel M, Roberts VA, Cooper PK, Tainer JA, (2008) XPD helicase structures and activities: insights into the cancer and aging phenotypes from XPD mutations. Cell 133: 789-800.
-
(2008)
Cell
, vol.133
, pp. 789-800
-
-
Fan, L.1
Fuss, J.O.2
Cheng, Q.J.3
Arvai, A.S.4
Hammel, M.5
Roberts, V.A.6
Cooper, P.K.7
Tainer, J.A.8
-
38
-
-
0033566657
-
Site-directed mutagenesis of motif III in PcrA helicase reveals a role in coupling ATP hydrolysis to strand separation
-
Dillingham MS, Soultanas P, Wigley DB, (1999) Site-directed mutagenesis of motif III in PcrA helicase reveals a role in coupling ATP hydrolysis to strand separation. Nucleic Acids Res 27: 3310-3317.
-
(1999)
Nucleic Acids Res
, vol.27
, pp. 3310-3317
-
-
Dillingham, M.S.1
Soultanas, P.2
Wigley, D.B.3
-
39
-
-
0035902592
-
Defining the roles of individual residues in the single-stranded DNA binding site of PcrA helicase
-
Dillingham MS, Soultanas P, Wiley P, Webb MR, Wigley DB, (2001) Defining the roles of individual residues in the single-stranded DNA binding site of PcrA helicase. Proc Natl Acad Sci USA 98: 8381-8387.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 8381-8387
-
-
Dillingham, M.S.1
Soultanas, P.2
Wiley, P.3
Webb, M.R.4
Wigley, D.B.5
-
40
-
-
10144248959
-
A partially functional DNA helicase II mutant defective in forming stable binary complexes with ATP and DNA - A role for helicase motif III
-
Brosh RM, Matson SW, (1996) A partially functional DNA helicase II mutant defective in forming stable binary complexes with ATP and DNA-a role for helicase motif III. J Biol Chem 271: 25360-25368.
-
(1996)
J Biol Chem
, vol.271
, pp. 25360-25368
-
-
Brosh, R.M.1
Matson, S.W.2
-
41
-
-
15444357274
-
A point mutation in Escherichia coli DNA helicase II renders the enzyme nonfunctional in two DNA repair pathways - Evidence for initiation of unwinding from a nick in vivo
-
Brosh RM, Matson SW, (1997) A point mutation in Escherichia coli DNA helicase II renders the enzyme nonfunctional in two DNA repair pathways-evidence for initiation of unwinding from a nick in vivo. J Biol Chem 272: 572-579.
-
(1997)
J Biol Chem
, vol.272
, pp. 572-579
-
-
Brosh, R.M.1
Matson, S.W.2
-
42
-
-
0141865522
-
High-resolution structure of the E. Coli RecQ helicase catalytic core
-
Bernstein DA, Zittel MC, Keck JL, (2003) High-resolution structure of the E. coli RecQ helicase catalytic core. EMBO J 22: 4910-4921.
-
(2003)
EMBO J
, vol.22
, pp. 4910-4921
-
-
Bernstein, D.A.1
Zittel, M.C.2
Keck, J.L.3
-
43
-
-
31144475762
-
Coupling DNA-binding and ATP hydrolysis in Escherichia coli RecQ: Role of a highly conserved aromatic-rich sequence
-
Zittel MC, Keck JL, (2005) Coupling DNA-binding and ATP hydrolysis in Escherichia coli RecQ: role of a highly conserved aromatic-rich sequence. Nucleic Acids Res 33: 6982-6991.
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 6982-6991
-
-
Zittel, M.C.1
Keck, J.L.2
-
44
-
-
84893382999
-
Structural mechanisms of PriA-mediated DNA replication restart
-
Bhattacharyya B, George NP, Thurmes TM, Zhou R, Jani N, Wessel SR, Sandler SJ, Ha T, Keck JL, (2014) Structural mechanisms of PriA-mediated DNA replication restart. Proc Natl Acad Sci USA 111: 1373-1378.
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, pp. 1373-1378
-
-
Bhattacharyya, B.1
George, N.P.2
Thurmes, T.M.3
Zhou, R.4
Jani, N.5
Wessel, S.R.6
Sandler, S.J.7
Ha, T.8
Keck, J.L.9
-
45
-
-
0035812836
-
Structural analysis of DNA replication fork reversal by RecG
-
Singleton MR, Scaife S, Wigley DB, (2001) Structural analysis of DNA replication fork reversal by RecG. Cell 107: 79-89.
-
(2001)
Cell
, vol.107
, pp. 79-89
-
-
Singleton, M.R.1
Scaife, S.2
Wigley, D.B.3
-
46
-
-
75849122854
-
Structural basis for DNA strand separation by the unconventional winged-helix domain of RecQ helicase WRN
-
Kitano K, Kim SY, Hakoshima T, (2010) Structural basis for DNA strand separation by the unconventional winged-helix domain of RecQ helicase WRN. Structure 18: 177-187.
-
(2010)
Structure
, vol.18
, pp. 177-187
-
-
Kitano, K.1
Kim, S.Y.2
Hakoshima, T.3
-
47
-
-
59049103795
-
Structure of the human RECQ1 helicase reveals a putative strand-separation pin
-
Pike AC, Shrestha B, Popuri V, Burgess-Brown N, Muzzolini L, Costantini S, Vindigni A, Gileadi O, (2009) Structure of the human RECQ1 helicase reveals a putative strand-separation pin. Proc Natl Acad Sci USA 106: 1039-1044.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 1039-1044
-
-
Pike, A.C.1
Shrestha, B.2
Popuri, V.3
Burgess-Brown, N.4
Muzzolini, L.5
Costantini, S.6
Vindigni, A.7
Gileadi, O.8
-
48
-
-
76249111702
-
Three conformational snapshots of the hepatitis C virus NS3 helicase reveal a ratchet translocation mechanism
-
Gu M, Rice CM, (2010) Three conformational snapshots of the hepatitis C virus NS3 helicase reveal a ratchet translocation mechanism. Proc Natl Acad Sci USA 107: 521-528.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 521-528
-
-
Gu, M.1
Rice, C.M.2
-
49
-
-
0242582359
-
Two novel conserved motifs in the hepatitis C virus NS3 protein critical for helicase action
-
Lam AM, Keeney D, Frick DN, (2003) Two novel conserved motifs in the hepatitis C virus NS3 protein critical for helicase action. J Biol Chem 278: 44514-44524.
-
(2003)
J Biol Chem
, vol.278
, pp. 44514-44524
-
-
Lam, A.M.1
Keeney, D.2
Frick, D.N.3
-
50
-
-
0032518490
-
Hepatitis C virus NS3 RNA helicase domain with a bound oligonucleotide: The crystal structure provides insights into the mode of unwinding
-
Kim JL, Morgenstern KA, Griffith JP, Dwyer MD, Thomson JA, Murcko MA, Lin C, Caron PR, (1998) Hepatitis C virus NS3 RNA helicase domain with a bound oligonucleotide: the crystal structure provides insights into the mode of unwinding. Structure 6: 89-100.
-
(1998)
Structure
, vol.6
, pp. 89-100
-
-
Kim, J.L.1
Morgenstern, K.A.2
Griffith, J.P.3
Dwyer, M.D.4
Thomson, J.A.5
Murcko, M.A.6
Lin, C.7
Caron, P.R.8
-
51
-
-
33645645084
-
Structural and biological identification of residues on the surface of NS3 helicase required for optimal replication of the hepatitis C virus
-
Mackintosh SG, Lu JZ, Jordan JB, Harrison MK, Sikora B, Sharma SD, Cameron CE, Raney KD, Sakon J, (2006) Structural and biological identification of residues on the surface of NS3 helicase required for optimal replication of the hepatitis C virus. J Biol Chem 281: 3528-3535.
-
(2006)
J Biol Chem
, vol.281
, pp. 3528-3535
-
-
Mackintosh, S.G.1
Lu, J.Z.2
Jordan, J.B.3
Harrison, M.K.4
Sikora, B.5
Sharma, S.D.6
Cameron, C.E.7
Raney, K.D.8
Sakon, J.9
-
52
-
-
17144385089
-
DNA binding by the substrate specificity (wedge) domain of RecG helicase suggests a role in processivity
-
Briggs GS, Mahdi AA, Wen Q, Lloyd RG, (2005) DNA binding by the substrate specificity (wedge) domain of RecG helicase suggests a role in processivity. J Biol Chem 280: 13921-13927.
-
(2005)
J Biol Chem
, vol.280
, pp. 13921-13927
-
-
Briggs, G.S.1
Mahdi, A.A.2
Wen, Q.3
Lloyd, R.G.4
-
53
-
-
0035902591
-
Rescue of stalled replication forks by RecG: Simultaneous translocation on the leading and lagging strand templates supports an active DNA unwinding model of fork reversal and Holliday junction formation
-
McGlynn P, Lloyd RG, (2001) Rescue of stalled replication forks by RecG: simultaneous translocation on the leading and lagging strand templates supports an active DNA unwinding model of fork reversal and Holliday junction formation. Proc Natl Acad Sci USA 98: 8227-8234.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 8227-8234
-
-
McGlynn, P.1
Lloyd, R.G.2
-
54
-
-
0033178272
-
RecG helicase activity at three- and four-strand DNA structures
-
McGlynn P, Lloyd RG, (1999) RecG helicase activity at three- and four-strand DNA structures. Nucleic Acids Res 27: 3049-3056.
-
(1999)
Nucleic Acids Res
, vol.27
, pp. 3049-3056
-
-
McGlynn, P.1
Lloyd, R.G.2
-
55
-
-
0035902573
-
Formation of Holliday junctions by regression of nascent DNA in intermediates containing stalled replication forks: RecG stimulates regression even when the DNA is negatively supercoiled
-
McGlynn P, Lloyd RG, Marians KJ, (2001) Formation of Holliday junctions by regression of nascent DNA in intermediates containing stalled replication forks: RecG stimulates regression even when the DNA is negatively supercoiled. Proc Natl Acad Sci USA 98: 8235-8240.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 8235-8240
-
-
McGlynn, P.1
Lloyd, R.G.2
Marians, K.J.3
-
56
-
-
38349091095
-
The iron-containing domain is essential in Rad3 helicases for coupling of ATP hydrolysis to DNA translocation and for targeting the helicase to the single-stranded DNA-double-stranded DNA junction
-
Pugh RA, Honda M, Leesley H, Thomas A, Lin Y, Nilges MJ, Cann IK, Spies M, (2008) The iron-containing domain is essential in Rad3 helicases for coupling of ATP hydrolysis to DNA translocation and for targeting the helicase to the single-stranded DNA-double-stranded DNA junction. J Biol Chem 283: 1732-1743.
-
(2008)
J Biol Chem
, vol.283
, pp. 1732-1743
-
-
Pugh, R.A.1
Honda, M.2
Leesley, H.3
Thomas, A.4
Lin, Y.5
Nilges, M.J.6
Cann, I.K.7
Spies, M.8
-
57
-
-
84857194573
-
Regulation of translocation polarity by helicase domain 1 in SF2B helicases
-
Pugh RA, Wu CG, Spies M, (2012) Regulation of translocation polarity by helicase domain 1 in SF2B helicases. EMBO J 31: 503-514.
-
(2012)
EMBO J
, vol.31
, pp. 503-514
-
-
Pugh, R.A.1
Wu, C.G.2
Spies, M.3
-
58
-
-
20744446399
-
Structure, function, and formation of biological iron-sulfur clusters
-
Johnson DC, Dean DR, Smith AD, Johnson MK, (2005) Structure, function, and formation of biological iron-sulfur clusters. Ann Rev Biochem 74: 247-281.
-
(2005)
Ann Rev Biochem
, vol.74
, pp. 247-281
-
-
Johnson, D.C.1
Dean, D.R.2
Smith, A.D.3
Johnson, M.K.4
-
59
-
-
0024400711
-
Endonuclease III is an iron-sulfur protein
-
Cunningham RP, Asahara H, Bank JF, Scholes CP, Salerno JC, Surerus K, Munck E, McCracken J, Peisach J, Emptage MH, (1989) Endonuclease III is an iron-sulfur protein. Biochemistry 28: 4450-4455.
-
(1989)
Biochemistry
, vol.28
, pp. 4450-4455
-
-
Cunningham, R.P.1
Asahara, H.2
Bank, J.F.3
Scholes, C.P.4
Salerno, J.C.5
Surerus, K.6
Munck, E.7
McCracken, J.8
Peisach, J.9
Emptage, M.H.10
-
60
-
-
34548492954
-
An iron-sulfur domain of the eukaryotic primase is essential for RNA primer synthesis
-
Klinge S, Hirst J, Maman JD, Krude T, Pellegrini L, (2007) An iron-sulfur domain of the eukaryotic primase is essential for RNA primer synthesis. Nat Struct Mol Biol 14: 875-877.
-
(2007)
Nat Struct Mol Biol
, vol.14
, pp. 875-877
-
-
Klinge, S.1
Hirst, J.2
Maman, J.D.3
Krude, T.4
Pellegrini, L.5
-
61
-
-
36348995555
-
An iron-sulfur cluster in the C-terminal domain of the p58 subunit of human DNA primase
-
Weiner BE, Huang H, Dattilo BM, Nilges MJ, Fanning E, Chazin WJ, (2007) An iron-sulfur cluster in the C-terminal domain of the p58 subunit of human DNA primase. J Biol Chem 282: 33444-33451.
-
(2007)
J Biol Chem
, vol.282
, pp. 33444-33451
-
-
Weiner, B.E.1
Huang, H.2
Dattilo, B.M.3
Nilges, M.J.4
Fanning, E.5
Chazin, W.J.6
-
62
-
-
77956363679
-
Insights into eukaryotic DNA priming from the structure and functional interactions of the 4Fe-4S cluster domain of human DNA primase
-
Vaithiyalingam S, Warren EM, Eichman BF, Chazin WJ, (2010) Insights into eukaryotic DNA priming from the structure and functional interactions of the 4Fe-4S cluster domain of human DNA primase. Proc Natl Acad Sci USA 107: 13684-13689.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 13684-13689
-
-
Vaithiyalingam, S.1
Warren, E.M.2
Eichman, B.F.3
Chazin, W.J.4
-
63
-
-
77958512174
-
Fanconi anemia group J mutation abolishes its DNA repair function by uncoupling DNA translocation from helicase activity or disruption of protein-DNA complexes
-
Wu Y, Sommers JA, Suhasini AN, Leonard T, Deakyne JS, Mazin AV, Shin-Ya K, Kitao H, Brosh RM, Jr, (2010) Fanconi anemia group J mutation abolishes its DNA repair function by uncoupling DNA translocation from helicase activity or disruption of protein-DNA complexes. Blood 116: 3780-3791.
-
(2010)
Blood
, vol.116
, pp. 3780-3791
-
-
Wu, Y.1
Sommers, J.A.2
Suhasini, A.N.3
Leonard, T.4
Deakyne, J.S.5
Mazin, A.V.6
Shin-Ya, K.7
Kitao, H.8
Brosh, Jr.R.M.9
-
64
-
-
0036699095
-
Disruption of dog-1 in Caenorhabditis elegans triggers deletions upstream of guanine-rich DNA
-
Cheung I, Schertzer M, Rose A, Lansdorp PM, (2002) Disruption of dog-1 in Caenorhabditis elegans triggers deletions upstream of guanine-rich DNA. Nat Gen 31: 405-409.
-
(2002)
Nat Gen
, vol.31
, pp. 405-409
-
-
Cheung, I.1
Schertzer, M.2
Rose, A.3
Lansdorp, P.M.4
-
65
-
-
64149092801
-
Redox control of the DNA damage-inducible protein DinG helicase activity via its iron-sulfur cluster
-
Ren B, Duan X, Ding H, (2009) Redox control of the DNA damage-inducible protein DinG helicase activity via its iron-sulfur cluster. J Biol Chem 284: 4829-4835.
-
(2009)
J Biol Chem
, vol.284
, pp. 4829-4835
-
-
Ren, B.1
Duan, X.2
Ding, H.3
-
66
-
-
80054726392
-
ATP-stimulated, DNA-mediated redox signaling by XPD, a DNA repair and transcription helicase
-
Mui TP, Fuss JO, Ishida JP, Tainer JA, Barton JK, (2011) ATP-stimulated, DNA-mediated redox signaling by XPD, a DNA repair and transcription helicase. J Am Chem Soc 133: 16378-16381.
-
(2011)
J Am Chem Soc
, vol.133
, pp. 16378-16381
-
-
Mui, T.P.1
Fuss, J.O.2
Ishida, J.P.3
Tainer, J.A.4
Barton, J.K.5
-
67
-
-
84857127226
-
DNA charge transport as a first step in coordinating the detection of lesions by repair proteins
-
Sontz PA, Mui TP, Fuss JO, Tainer JA, Barton JK, (2012) DNA charge transport as a first step in coordinating the detection of lesions by repair proteins. Proc Natl Acad Sci USA 109: 1856-1861.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 1856-1861
-
-
Sontz, P.A.1
Mui, T.P.2
Fuss, J.O.3
Tainer, J.A.4
Barton, J.K.5
-
68
-
-
84857195289
-
Functional and structural studies of the nucleotide excision repair helicase XPD suggest a polarity for DNA translocation
-
Kuper J, Wolski SC, Michels G, Kisker C, (2012) Functional and structural studies of the nucleotide excision repair helicase XPD suggest a polarity for DNA translocation. EMBO J 31: 494-502.
-
(2012)
EMBO J
, vol.31
, pp. 494-502
-
-
Kuper, J.1
Wolski, S.C.2
Michels, G.3
Kisker, C.4
-
69
-
-
33748428875
-
The DNA repair helicases XPD and FancJ have essential iron-sulfur domains
-
Rudolf J, Makrantoni V, Ingledew WJ, Stark MJ, White MF, (2006) The DNA repair helicases XPD and FancJ have essential iron-sulfur domains. Mol Cell 23: 801-808.
-
(2006)
Mol Cell
, vol.23
, pp. 801-808
-
-
Rudolf, J.1
Makrantoni, V.2
Ingledew, W.J.3
Stark, M.J.4
White, M.F.5
-
70
-
-
65549136266
-
An iron-sulfur cluster is essential for the binding of broken DNA by AddAB-type helicase-nucleases
-
Yeeles JT, Cammack R, Dillingham MS, (2009) An iron-sulfur cluster is essential for the binding of broken DNA by AddAB-type helicase-nucleases. J Biol Chem 284: 7746-7755.
-
(2009)
J Biol Chem
, vol.284
, pp. 7746-7755
-
-
Yeeles, J.T.1
Cammack, R.2
Dillingham, M.S.3
-
71
-
-
76749101865
-
Recruitment to stalled replication forks of the PriA DNA helicase and replisome-loading activities is essential for survival
-
Gabbai CB, Marians KJ, (2010) Recruitment to stalled replication forks of the PriA DNA helicase and replisome-loading activities is essential for survival. DNA Repair 9: 202-209.
-
(2010)
DNA Repair
, vol.9
, pp. 202-209
-
-
Gabbai, C.B.1
Marians, K.J.2
-
72
-
-
0027412617
-
Helicase-deficient cysteine to glycine substitution mutants of Escherichia coli replication protein PriA retain single-stranded DNA-dependent ATPase activity. Zn2+ stimulation of mutant PriA helicase and primosome assembly activities
-
Zavitz KH, Marians KJ, (1993) Helicase-deficient cysteine to glycine substitution mutants of Escherichia coli replication protein PriA retain single-stranded DNA-dependent ATPase activity. Zn2+ stimulation of mutant PriA helicase and primosome assembly activities. J Biol Chem 268: 4337-4346.
-
(1993)
J Biol Chem
, vol.268
, pp. 4337-4346
-
-
Zavitz, K.H.1
Marians, K.J.2
-
73
-
-
0029666278
-
The ordered assembly of the phiX174-type primosome. III. PriB facilitates complex formation between PriA and DnaT
-
Liu J, Nurse P, Marians KJ, (1996) The ordered assembly of the phiX174-type primosome. III. PriB facilitates complex formation between PriA and DnaT. J Biol Chem 271: 15656-15661.
-
(1996)
J Biol Chem
, vol.271
, pp. 15656-15661
-
-
Liu, J.1
Nurse, P.2
Marians, K.J.3
|