Dopamine D3 Receptor Ser9Gly and Catechol-O-Methyltransferase Val158Met polymorphisms and acute pain in sickle cell disease

Anesthesia and Analgesia

Volumn 119, Issue 5, 2014, Pages 1201-1207

  Jhun, Ellie ^a   He, Ying ^a   Yao, Yingwei ^a   Molokie, Robert E ^a,b   Wilkie, Diana J ^a,c   Jim Wang, Zaijie ^a,c  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b UNIVERSITY OF ILLINOIS   (United States)

^c JESSE BROWN VA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATECHOL METHYLTRANSFERASE; DOPAMINE 3 RECEPTOR; GLYCINE; METHIONINE; SERINE; VALINE; DNA;

ADULT; ALLELE; ARTICLE; CONTROLLED STUDY; FEMALE; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HETEROZYGOTE; HOMOZYGOTE; HUMAN; MAJOR CLINICAL STUDY; MALE; MCGILL PAIN QUESTIONNAIRE; PAIN; SICKLE CELL ANEMIA; SINGLE NUCLEOTIDE POLYMORPHISM; ACUTE PAIN; COMPLICATION; GENETIC POLYMORPHISM; GENETICS; PAIN MEASUREMENT;

ACUTE PAIN; ADULT; ALLELES; ANEMIA, SICKLE CELL; CATECHOL O-METHYLTRANSFERASE; DNA; FEMALE; GENOTYPE; HUMANS; MALE; PAIN MEASUREMENT; POLYMORPHISM, GENETIC; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, DOPAMINE D3;

EID: 84914672475     PISSN: 00032999     EISSN: 15267598     Source Type: Journal    
DOI: 10.1213/ANE.0000000000000382     Document Type: Article

References (52)

1. Platt OS, Thorington BD, Brambilla DJ, Milner PF, Rosse WF, Vichinsky E, Kinney TR. Pain in sickle cell disease. Rates and risk factors. N Engl J Med 1991;325:11-6
2. Wilkie DJ, Molokie R, Boyd-Seal D, Suarez ML, Kim YO, Zong S, Wittert H, Zhao Z, Saunthararajah Y, Wang ZJ. Patient-reported outcomes: descriptors of nociceptive and neuropathic pain and barriers to effective pain management in adult outpatients with sickle cell disease. J Natl Med Assoc 2010;102:18-27
3. Brousseau DC, Owens PL, Mosso AL, Panepinto JA, Steiner CA. Acute care utilization and rehospitalizations for sickle cell disease. JAMA 2010;303:1288-94
4. Rees DC, Williams TN, Gladwin MT. Sickle-cell disease. Lancet 2010;376:2018-31
5. Ballas SK, Lusardi M. Hospital readmission for adult acute sickle cell painful episodes: frequency, etiology, and prognostic significance. Am J Hematol 2005;79:17-25
6. Smith WR, Penberthy LT, Bovbjerg VE, McClish DK, Roberts JD, Dahman B, Aisiku IP, Levenson JL, Roseff SD. Daily assessment of pain in adults with sickle cell disease. Ann Intern Med 2008;148:94-101
7. Molokie RE, Wang ZJ, Wilkie DJ. Presence of neuropathic pain as an underlying mechanism for pain associated with cold weather in patients with sickle cell disease. Med Hypotheses 2011;77:491-3
8. Wang ZJ, Wilkie DJ, Molokie R. Neurobiological mechanisms of pain in sickle cell disease. Hematology Am Soc Hematol Educ Program 2010;2010:403-8
9. Finan PH, Smith MT. The comorbidity of insomnia, chronic pain, and depression: dopamine as a putative mechanism. Sleep Med Rev 2013;17:173-83
10. Delgado PL. Common pathways of depression and pain. J Clin Psychiatry 2004;65 Suppl 12:16-9
11. Wood PB. Role of central dopamine in pain and analgesia. Expert Rev Neurother 2008;8:781-97
12. Axelrod J, Tomchick R. Enzymatic O-methylation of epinephrine and other catechols. J Biol Chem 1958;233:702-5
13. Tammimäki A, Männistö PT. Catechol-O-methyltransferase gene polymorphism and chronic human pain: a systematic review and meta-Analysis. Pharmacogenet Genomics 2012;22:673-91
14. Zubieta JK, Heitzeg MM, Smith YR, Bueller JA, Xu K, Xu Y, Koeppe RA, Stohler CS, Goldman D. COMT val158met genotype affects mu-opioid neurotransmitter responses to a pain stressor. Science 2003;299:1240-3
15. Potvin S, Larouche A, Normand E, de Souza JB, Gaumond I, Grignon S, Marchand S. DRD3 Ser9Gly polymorphism is related to thermal pain perception and modulation in chronic widespread pain patients and healthy controls. J Pain 2009;10:969-75
16. Ezenwa MO, Molokie RE, Wang ZJ, Yao Y, Suarez ML, Angulo V, Wilkie DJ. Outpatient pain predicts subsequent one-year acute health care utilization among adults with sickle cell disease. J Pain Symptom Manage 2014;48:65-74
17. Melzack R. The McGill Pain Questionnaire: major properties and scoring methods. Pain 1975;1:277-99
18. Ngamkham S, Holden JE, Wilkie DJ. Differences in pain location, intensity, and quality by pain pattern in outpatients with cancer. Cancer Nurs 2011;34:228-37
19. Wilkie DJ, Judge MK, Berry DL, Dell J, Zong S, Gilespie R. Usability of a computerized PAINReportIt in the general public with pain and people with cancer pain. J Pain Symptom Manage 2003;25:213-24
20. Miller SA, Dykes DD, Polesky HF. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 1988;16:1215
21. Vandenbergh DJ, Anthony K, Whitfield KE. Optimizing DNA yield from buccal swabs in the elderly: attempts to promote buccal cell growth in culture. Am J Hum Biol 2003;15:637-42
22. Armero P, Muriel C, Santos J, Sanchez-Montero FJ, Rodríguez RE, González-Sarmiento R. COMT (Val158Met) polymorphism is not associated to neuropathic pain in a Spanish population. Eur J Pain 2005;9:229-32
23. Firth D. Bias reduction of maximum likelihood estimates. Biometrika 1993;80:27-38.
24. Cameron A, Trivedi, PK. Regression Analysis of Count Data. 1st ed. Cambridge University Press, 1998
25. R Development Core Team. R: A Language and Environment for Statistical Computing. Vienna, Austria: R Foundation for Statistical Computing, 2011
26. Crocq MA, Mant R, Asherson P, Williams J, Hode Y, Mayerova A, Collier D, Lannfelt L, Sokoloff P, Schwartz JC. Association between schizophrenia and homozygosity at the dopamine D3 receptor gene. J Med Genet 1992;29:858-60
27. Comings DE, Gonzalez N, Wu S, Saucier G, Johnson P, Verde R, MacMurray JP. Homozygosity at the dopamine DRD3 receptor gene in cocaine dependence. Mol Psychiatry 1999;4:484-7
28. Comings DE, Muhleman D, Dietz G, Dino M, LeGro R, Gade R. Association between Tourette's syndrome and homozygosity at the dopamine D3 receptor gene. Lancet 1993;341:906
29. Duaux E, Gorwood P, Griffon N, Bourdel MC, Sautel F, Sokoloff P, Schwartz JC, Ades J, Lôo H, Poirier MF. Homozygosity at the dopamine D3 receptor gene is associated with opiate dependence. Mol Psychiatry 1998;3:333-6
30. Krebs MO, Sautel F, Bourdel MC, Sokoloff P, Schwartz JC, Olié JP, Lôo H, Poirier MF. Dopamine D3 receptor gene variants and substance abuse in schizophrenia. Mol Psychiatry 1998;3:337-41
31. Sebastiani P, Solovieff N, Hartley SW, Milton JN, Riva A, Dworkis DA, Melista E, Klings ES, Garrett ME, Telen MJ, Ashley-Koch A, Baldwin CT, Steinberg MH. Genetic modifiers of the severity of sickle cell anemia identified through a genome-wide association study. Am J Hematol 2010;85:29-35
32. Jeanneteau F, Funalot B, Jankovic J, Deng H, Lagarde JP, Lucotte G, Sokoloff P. A functional variant of the dopamine D3 receptor is associated with risk and age-At-onset of essential tremor. Proc Natl Acad Sci U S A 2006;103:10753-8
33. Lundstrom K, Turpin MP. Proposed schizophrenia-related gene polymorphism: expression of the Ser9Gly mutant human dopamine D3 receptor with the Semliki Forest virus system. Biochem Biophys Res Commun 1996;225:1068-72
34. Savitz J, Hodgkinson CA, Martin-Soelch C, Shen PH, Szczepanik J, Nugent A, Herscovitch P, Grace AA, Goldman D, Drevets WC. The functional DRD3 Ser9Gly polymorphism (rs6280) is pleiotropic, affecting reward as well as movement. PLoS One 2013;8:e54108
35. Wood PB. Mesolimbic dopaminergic mechanisms and pain control. Pain 2006;120:230-4
36. Ballas SK, Gupta K, Adams-Graves P. Sickle cell pain: a critical reappraisal. Blood 2012;120:3647-56
37. Sellis D, Callahan BJ, Petrov DA, Messer PW. Heterozygote advantage as a natural consequence of adaptation in diploids. Proc Natl Acad Sci U S A 2011;108:20666-71
38. Jönsson EG, Kaiser R, Brockmöller J, Nimgaonkar VL, Crocq MA. Meta-Analysis of the dopamine D3 receptor gene (DRD3) Ser9Gly variant and schizophrenia. Psychiatr Genet 2004;14:9-12
39. Jönsson E, Sedvall G, Brené S, Gustavsson JP, Geijer T, Terenius L, Crocq MA, Lannfelt L, Tylec A, Sokoloff P, Schwartz JC, Wiesel FA. Dopamine-related genes and their relationships to monoamine metabolites in CSF. Biol Psychiatry 1996;40:1032-43
40. Treister R, Pud D, Ebstein RP, Laiba E, Gershon E, Haddad M, Eisenberg E. Associations between polymorphisms in dopamine neurotransmitter pathway genes and pain response in healthy humans. Pain 2009;147:187-93
41. Bilder RM, Volavka J, Lachman HM, Grace AA. The catechol-O-methyltransferase polymorphism: relations to the tonic-phasic dopamine hypothesis and neuropsychiatric phenotypes. Neuropsychopharmacology 2004;29:1943-61
42. Li T, Sham PC, Vallada H, Xie T, Tang X, Murray RM, Liu X, Collier DA. Preferential transmission of the high activity allele of COMT in schizophrenia. Psychiatr Genet 1996;6:131-3
43. Finan PH, Zautra AJ, Davis MC, Lemery-Chalfant K, Covault J, Tennen H. COMT moderates the relation of daily maladaptive coping and pain in fibromyalgia. Pain 2011;152:300-7
44. Brennan PA, Hammen C, Sylvers P, Bor W, Najman J, Lind P, Montgomery G, Smith AK. Interactions between the COMT Val108/158Met polymorphism and maternal prenatal smoking predict aggressive behavior outcomes. Biol Psychol 2011;87:99-105
45. Pivac N, Pregelj P, Nikolac M, Zupanc T, Nedic G, Muck Seler D, Paska AV. The association between catechol-O-methyl-transferase Val(108/158)Met polymorphism and suicide. Genes Brain Behav 2011;10:565-9
46. Loggia ML, Jensen K, Gollub RL, Wasan AD, Edwards RR, Kong J. The catechol-O-methyltransferase (COMT) val158met polymorphism affects brain responses to repeated painful stimuli. PLoS One 2011;6:e27764
47. Martínez-Jauand M, Sitges C, Rodríguez V, Picornell A, Ramon M, Buskila D, Montoya P. Pain sensitivity in fibromyalgia is associated with catechol-O-methyltransferase (COMT) gene. Eur J Pain 2013;17:16-27
48. Jensen KB, Lonsdorf TB, Schalling M, Kosek E, Ingvar M. Increased sensitivity to thermal pain following a single opiate dose is influenced by the COMT val(158)met polymorphism. PLoS One 2009;4:e6016
49. Kim H, Lee H, Rowan J, Brahim J, Dionne RA. Genetic polymorphisms in monoamine neurotransmitter systems show only weak association with acute post-surgical pain in humans. Mol Pain 2006;2:24
50. Diatchenko L, Nackley AG, Slade GD, Bhalang K, Belfer I, Max MB, Goldman D, Maixner W. Catechol-O-methyltransferase gene polymorphisms are associated with multiple pain-evoking stimuli. Pain 2006;125:216-24
51. Rakvag TT, Ross JR, Sato H, Skorpen F, Kaasa S, Klepstad P. Genetic variation in the catechol-O-methyltransferase (COMT) gene and morphine requirements in cancer patients with pain. Mol Pain 2008;4:64
52. Treister R, Pud D, Ebstein RP, Laiba E, Raz Y, Gershon E, Haddad M, Eisenberg E. Association between polymorphisms in serotonin and dopamine-related genes and endogenous pain modulation. J Pain 2011;12:875-83