Increased sensitivity to thermal pain following a single opiate dose is influenced by the COMT val158 met polymorphism

PLoS ONE

Volumn 4, Issue 6, 2009, Pages

  Jensen, Karin B ^a   Lonsdorf, Tina B ^a   Schalling, Martin ^a   Kosek, Eva ^a   Ingvar, Martin ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CATECHOL METHYLTRANSFERASE; METHIONINE; MU OPIATE RECEPTOR; PLACEBO; REMIFENTANIL; SODIUM CHLORIDE; VALINE; NARCOTIC ANALGESIC AGENT;

ADULT; ALLELE; ANALGESIA; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG RECEPTOR BINDING; FEMALE; GENETIC POLYMORPHISM; GENOTYPE; HEAT SENSITIVITY; HOMOZYGOSITY; HUMAN; HUMAN EXPERIMENT; HYPERALGESIA; MALE; NERVE BLOCK; NOCICEPTION; NORMAL HUMAN; TEMPERATURE SENSITIVITY; THERMAL PAIN; VISUAL ANALOG SCALE; CHEMISTRY; GENETICS; HEAT; PAIN; PAIN THRESHOLD; PHARMACOGENETICS;

ADULT; ALLELES; ANALGESICS, OPIOID; CATECHOL O-METHYLTRANSFERASE; FEMALE; GENOTYPE; HOT TEMPERATURE; HUMANS; MALE; METHIONINE; PAIN; PAIN THRESHOLD; PHARMACOGENETICS; POLYMORPHISM, GENETIC; VALINE;

EID: 67650308690     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0006016     Document Type: Article

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