A functional variant of the dopamine D3 receptor is associated with risk and age-at-onset of essential tremor

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 28, 2006, Pages 10753-10758

  Jeanneteau, Freddy ^a   Funalot, Benoît ^a,b   Jankovic, Joseph ^c   Deng, Hao ^c   Lagarde, Jean Pierre ^d   Lucotte, Gérard ^e   Sokoloff, Pierre ^a,f  

^a INSERM   (France)

^b CENTRE HOSPITALIER SAINTE ANNE   (France)

^c BAYLOR COLLEGE OF MEDICINE   (United States)

^d PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^e Centre de Neurogenetique Moleculaire   (France)

^f INSTITUT DE RECHERCHE PIERRE FABRE   (France)

Author keywords

Dopamine receptor; Gain of function; Gene dosage; Movement disorder; Polymorphism

Indexed keywords

CYCLIC AMP; DOPAMINE; DOPAMINE 3 RECEPTOR; DOPAMINE 3 RECEPTOR BLOCKING AGENT; DOPAMINE 3 RECEPTOR STIMULATING AGENT; GLYCINE; MITOGEN ACTIVATED PROTEIN KINASE; SERINE;

ADOLESCENT; ADULT; AGED; ARTICLE; AUTOSOMAL DOMINANT DISORDER; BINDING AFFINITY; CELL STRAIN HEK293; CHROMOSOME 3Q; CONTROLLED STUDY; DISEASE SEVERITY; DNA FLANKING REGION; ESSENTIAL TREMOR; FAMILIAL DISEASE; FEMALE; FRANCE; GENE DOSAGE; GENE LOCATION; GENE LOCUS; GENETIC POLYMORPHISM; GENETIC TRANSFECTION; GLYCOSYLATION; HETEROZYGOTE; HOMOZYGOTE; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; MOTOR DYSFUNCTION; ONSET AGE; PARKINSON DISEASE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ADOLESCENT; ADULT; AGE OF ONSET; AGED; AGED, 80 AND OVER; AMINO ACID SEQUENCE; CASE-CONTROL STUDIES; CELLS, CULTURED; CHILD; DOPAMINE; ESSENTIAL TREMOR; FEMALE; FRANCE; GENETIC PREDISPOSITION TO DISEASE; GLYCINE; HUMANS; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; PEDIGREE; RECEPTORS, DOPAMINE D3; SERINE;

EID: 33746043780     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0508189103     Document Type: Article

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