Proposed schizophrenia-related gene polymorphism: Expression of the Ser9Gly mutant human dopamine D3 receptor with the Semliki Forest virus system

Biochemical and Biophysical Research Communications

Volumn 225, Issue 3, 1996, Pages 1068-1072

  Lundstrom, Kenneth ^a,b   Turpin, Michael P ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

^b GLAXO INST FOR MOLECULAR BIOLOGY   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

2 DIPROPYLAMINO 1,2,3,4 TETRAHYDRO 6 (4 METHOXYPHENYLSULFONYLMETHYL)NAPHTHALENE; 2 DIPROPYLAMINO 7 HYDROXYTETRALIN; 4' ACETYL N [4 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]BUTYL]BIPHENYL 4 CARBOXAMIDE; CHLORPROMAZINE; DOPAMINE; DOPAMINE 3 RECEPTOR; DOPAMINE RECEPTOR AFFECTING AGENT; GR 99841; HALOPERIDOL; RACLOPRIDE; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DNA POLYMORPHISM; EXPRESSION VECTOR; GENE EXPRESSION; GENE MUTATION; GENETIC POLYMORPHISM; GENETIC RISK; HOMOZYGOTE; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR BINDING; RECEPTOR GENE; SCHIZOPHRENIA; SEMLIKI FOREST ALPHAVIRUS; SITE DIRECTED MUTAGENESIS;

EID: 0030598907     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.1996.1296     Document Type: Article

References (20)

1. 1. Sokoloff, P., Giros, B., Martres, M.-P., Bouthenet, M.-L., and Scwarz, J. C. (1990) Nature 347, 146-151.
2. 2. Schwarz, J.-C., Levesque, D., Martres, M.-P., and Sokoloff, P. (1993) Clin. Neuropharmacol. 16, 295-314.
3. 3. Sabate, O., Campion, D., d'Amato, T., Martres, M. P., Sokoloff, P., Giros, B., Leboyer, M., Jay, M., Guedj, F., and Thibaut, F. (1994) Am. J. Psychiatr. 151, 107-111.
4. 4. Crocq, M. A., Mant, R., Asherson, P., Williams, J., Hode, Y., Mayerova, A., Collier, D., Lannfeldt, L., Sokoloff, P., and Schwarz, J. C. (1992) J. Med. Genet. 29, 858-860.
5. 5. Mant, R., Williams, J., Asherson, P., Parfitt, E., McGuffin, P., and Owen, M. J. (1994) Am. J. Med. Genet. 54, 21-26.
6. 6. Nanko, S., Sasaki, T., Fukuda, R., Hattori, M., Dai, X. Y., Kazamatsuri, H., Kuwata, S., Jujui, T., and Gill, M. (1993) Hum. Genet. 92, 336-338.
7. 7. Saha, N., Tsoi, W. F., Low, P. S., Basair, J., and Tay, J. S. (1994) Psychiatr. Genet. 4, 201-204.
8. 8. Sung, C. H., Schneider, B. G., Agarwal, N., Papermaster, D. S., and Nathans, J. (1991) Proc. Natl. Acad. Sci. 88, 8840-8844.
9. 9. Liljestrom, P., and Garoff, H. (1991) Bio/Technology 9, 1356-1361.
10. 10. Maniatis, T., Fritsch, E. F., and Sambrook, J. (1982) Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
11. 11. Berglund, P., Sjoberg, M., Garoff, H., Atkins, G. J., Sheahan, B. J., and Liljestrom, P. (1993) Bio/Technology 11, 916-920.
12. 12. Lundstrom, K., Mills, A., Buell, G., Allet, E., Adami, N., and Liljestrom, P. (1994) Eur. J. Biochem. 224, 917-921.
13. 13. Laemmli, U. K. (1970) Nature 227, 680-685.
14. 14. Bylund, D. B., and Yamamura, H. I. (1990) in Methods in Neurotransmitter Receptor Analysis (Yamamura, H. I., Enna, S. J., and Kuhar, M. J., Eds.), pp. 1-35. Raven Press, New York.
15. 15. Murray, P. J., Helden, R. M., Johnson, M. R., Robertson, G. M., Scopes, D. I. C., Stokes, M., Wadman, S., Whitehead, J. W. F., Hayes, A. G., Kilpatrick, G. J., Large, C., Stubbs, C., and Turpin, M. (1995) Bioorg Med. Chem. Lett. 6, 403-408.
16. 16. Murray, P. J., Harrison, L. A., Johnson, M. R., Robertson, G. M., Scopes, D. I. C., Bull, D. R., Graham, E. A., Hayes, A. G., Kilpatrick, G. J., den Daas, I., Large, C., Sheehan, M. J., Stubbs, C. M., and Turpin, M. P. (1995) Bioorg. Med. Chem. Lett. 5, 219-222.
17. 17. Rovati, G. E., Rodbard, D., and Munson, P. J. (1989) Anal. Biochem. 174, 636-649.
18. 18. Lundstrom, K., Mills, A., Allet, E., Ceszkowski, K., Agudo, G., Chollet, A., and Liljestrom, P. (1995) J. Receptor & Signal Transduction Res. 15, 23-32.
19. 19. Lundstrom, K. (1996) Focus, in press.
20. 20. Blasey, H., Lundstrom, K., Tate, S., and Bernard, A. (1996) Cytotechnology, in press.