Dietary nitrite supplementation improves insulin resistance in type 2 diabetic KKAy mice

Nitric Oxide - Biology and Chemistry

Volumn 44, Issue , 2015, Pages 31-38

  Ohtake, Kazuo ^a   Nakano, Genya ^a   Ehara, Nobuyuki ^a   Sonoda, Kunihiro ^b   Ito, Junta ^c   Uchida, Hiroyuki ^a   Kobayashi, Jun ^a  

^a JOSAI UNIVERSITY   (Japan)

^b KINJO GAKUIN UNIVERSITY   (Japan)

^c MEIKAI UNIVERSITY SCHOOL OF DENTISTRY   (Japan)

Author keywords

Dietary nitrite nitrate; Glucose transporter 4; Insulin resistance; Type 2 diabetes mellitus

Indexed keywords

GLUCOSE TRANSPORTER 4; INSULIN; NITRATE; NITRIC OXIDE; NITRITE; PROTEIN KINASE B; PROTEIN P85; CYTOKINE; GLUCOSE BLOOD LEVEL; SLC2A4 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD SAMPLING; BODY WEIGHT; CONTROLLED STUDY; DIET SUPPLEMENTATION; ENDOTHELIAL DYSFUNCTION; FOOD INTAKE; GASTROCNEMIUS MUSCLE; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYPERGLYCEMIA; IMPAIRED GLUCOSE TOLERANCE; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; INSULIN SENSITIVITY; INTRAABDOMINAL FAT; MALE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ADIPOSE TISSUE; ANIMAL; C57BL MOUSE; CYTOLOGY; DRUG EFFECTS; EATING; EXPERIMENTAL DIABETES MELLITUS; METABOLISM; TRANSGENIC MOUSE;

MUS;

ADIPOSE TISSUE; ANIMALS; BLOOD GLUCOSE; BODY WEIGHT; CYTOKINES; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 2; EATING; GLUCOSE TRANSPORTER TYPE 4; INSULIN RESISTANCE; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NITRITES;

EID: 84914165899     PISSN: 10898603     EISSN: 10898611     Source Type: Journal    
DOI: 10.1016/j.niox.2014.11.009     Document Type: Article

References (39)

1. E.D. Abel Insulin signaling in heart muscle: lessons from genetically engineered mouse models Curr. Hypertens. Rep 6 2004 416 423
2. J.O. Lundberg, M.T. Gladwin, A. Ahluwalia, N. Benjamin, N.S. Bryan, and A. Butler Nitrate and nitrite in biology, nutrition and therapeutics Nat. Chem. Biol 5 2009 865 869
3. U.N. Das Insulin: an endogenous cardioprotector Curr. Opin. Crit. Care 9 2003 375 383
4. H. Wang, A.X. Wang, K. Aylor, and E.J. Barrett Nitric oxide directly promotes vascular endothelial insulin transport Diabetes 62 2013 4030 4042
5. J. Kim, M. Montagnani, K.K. Koh, and M.J. Quon Reciprocal relationship between insulin resistance and endothelial dysfunction. Molecular and pathophysiological mechanisms Circulation 113 2006 1888 1904
6. H. Duplain, R. Burcelin, C. Sartori, S. Cook, M. Egli, and M. Lepori Insulin resistance, hyperlipidemia, and hypertension in mice lacking endothelial nitric oxide synthase Circulation 104 2001 342 345
7. B.E. Sansbury, and B.G. Hill Regulation of obesity and insulin resistance by nitric oxide Free Radic. Biol. Med 73 2014 383 399
8. M. Carlstrom, F.J. Larsen, T. Nystrom, M. Hezel, S. Borniquel, and E. Weitzberg Dietary inorganic nitrate reverses features of metabolic syndrome in endothelial nitric oxide synthase-deficient mice Proc. Natl. Acad. Sci. U.S.A. 107 2010 17716 17720
9. I.I.I.E.R. Mohler, W.R. Hiatt, H.L. Gornik, C.G. Kevil, A. Quyyumi, and W.G. Haynes Sodium nitrite in patients with peripheral artery and diabetes mellitus: safety, walking distance and endothelial function Vasc. Med 19 2014 9 17
10. y mice: regulation of PKB/GLUT4 signaling in skeletal muscle J. Ethnopharmacol 127 2010 32 37
11. T. Ishizuka, P. Klepcyk, S. Liu, L. Panko, S. Liu, and E.M. Gibbs Effects of overexpression of human GLUT4 gene on maternal diabetes and fetal growth in spontaneous gestational diabetic C57BLKS/J Lepr(db/+) mice Diabetes 48 1999 1061 1069
12. A. Okuno, H. Tamemoto, K. Tobe, K. Ueki, Y. Mori, and K. Iwamoto Troglitazone increases the number of small adipocytes without the change of white adipose tissue mass in obese Zucker rats J. Clin. Invest 101 1998 1354 1361
13. N.T. Dang, R. Mukai, K. Yoshida, and H. Ashida D-pinitol and myo-inositol stimulate translocation of glucose transporter 4 in skeletal muscle of C57BL/6 mice Biosci. Biotechnol. Biochem 74 2010 1062 1067
14. K. Ohtake, Y. Ishiyama, H. Uchida, E. Muraki, and J. Kobayashi Dietary nitrite inhibits early glomerular injury in streptozotocin-induced diabetic nephropathy in rats Nitric Oxide 17 2007 75 81
15. K. Ohtake, M. Koga, H. Uchida, K. Sonoda, J. Ito, and M. Uchida Oral nitrite ameliorates dextran sulfate sodium-induced acute experimental colitis in mice Nitric Oxide 23 2010 65 73
16. S.E. Shoelson, J. Lee, and A.B. Goldfine Inflammation and insulin resistance J. Clin. Invest 116 2006 1793 1801
17. M. Guerre-Millo Adipose tissue and adipokines: for better or worse Diabetes Metab 30 2004 13 19
18. S.M. Reyna, S. Ghosh, P. Tantiwong, C.S.R. Meka, P. Eagan, and C.P. Jenkinson Elevated toll-like receptor 4 expression and signaling in muscle from insulin-resistant subjects Diabetes 57 2008 2595 2602
19. D.T. Hess, A. Matsumoto, S.O. Kim, H.E. Marshall, and J.S. Stamler Protein S-nitrosylation: purview and parameters Nat. Rev. Mol. Cell. Bio 6 2005 150 165
20. C. de Luca, and J.M. Olefsky Inflammation and insulin resistance FEBS Lett 582 2008 97 105
21. B. Draznin Molecular mechanisms of insulin resistance: serine phosphorylation of insulin receptor substrate-1 and increased expression of p85α. The two sides of a coin Diabetes 55 2006 2392 2397
22. K.H. Fisher-Wellman, and P.D. Neufer Linking mitochondrial bioenergetics to insulin resistance via redox biology Trends Endocrinol. Metab 23 2012 142 153
23. M.A. Carvalho-Filho, M. Ueno, S.M. Hirabara, A.B. Seabra, J.B.C. Carvalheria, and M.G. Oliveira S-nitrosation of the insulin receptor, insulin receptor substrate 1, and protein kinase B/Akt. A novel mechanism of insulin resistance Diabetes 54 2005 959 967
24. M.F. Hsu, and T.C. Meng Enhancement of insulin responsiveness by nitric oxide-mediated inactivation of protein-tyrosine phosphatases J. Biol. Chem 285 2010 7919 7928
25. J.M. Richey The vascular endothelium, a benign restrictive barrier? No! Role of nitric oxide in regulating insulin action Diabetes 62 2013 4006 4008
26. H. Jiang, A.C. Torregrossa, A. Potts, D. Pierini, M. Aranke, and H.K. Garg Dietary nitrite improves insulin signaling through GLUT4 translocation Free Radic. Biol. Med 67 2014 51 57
27. F.J. Larsen, T.A. Schiffer, S. Borniquel, K. Sahlin, B. Ekblom, and J.O. Lundberg Dietary inorganic nitrate improves mitochondrial efficiency in humans Cell Metab 13 2011 149 159
28. T. Nystrom, H. Ortsater, Z. Huang, F. Zhang, F.J. Larsen, and E. Weitzberg Inorganic nitrite stimulates pancreatic islet blood flow and insulin secretion Free Radic. Biol. Med 53 2012 1017 1023
29. N.K.H. Khoo, L. Mo, S. Zharikov, C. Kamga, K. Quesnelle, and F. Golin-Bisello Nitrite augments glucose uptake in adipocytes through the protein kinase A-dependent stimulation of mitochondrial fusion Free Radic. Biol. Med 70 2014 45 53
30. N.O. Rizzo, E. Maloney, M. Pham, I. Luttrell, H. Wessells, and S. Tateya Reduced NO-cGMP signaling contributes to vascular inflammation and insulin resistance induced by high-fat feeding Arterioscler. Thromb. Vasc. Biol 30 2010 758 765
31. S.R. Kashyap, L.J. Roman, J. Lamont, B.S.S. Masters, M. Bajaj, and S. Suraamornkul Insulin resistance is associated with impaired nitric oxide synthase activity in skeletal muscle of type 2 diabetic subjects J. Clin. Endocrinol. Metab 90 2005 1100 1105
32. D.L. Archer Evidence that ingested nitrate and nitrite are beneficial to health J. Food Prot 65 2002 872 875
33. N.S. Bryan, D.D. Alexander, J.R. Coughlin, A.L. Milkowski, and P. Boffetta ingested nitrate and nitrite and stomach cancer risk: an updated review Food Chem. Toxicol 50 2012 3646 3665
34. M.L.1. Fernandez, R. Ruiz, M.A. Gonzalez, R. Ramirez-Lorca, C. Couto, and A. Ramos Association of NOS3 gene with metabolic syndrome in hypertensive patients Thromb. Haemost 92 2 2004 413 418
35. L.D. Monti, C. Barlassina, L. Citterio, E. Galluccio, C. Berzuini, and E. Setola Endothelial nitric oxide synthase polymorphisms are associated with type 2 diabetes and the insulin resistance syndrome Diabetes 52 5 2003 1270 1275
36. N.S. Bryan, B.O. Fernandez, S.M. Bauer, M.F. Garcia-Saura, A.B. Milsom, and T. Rassaf Nitrite is a signaling molecule and regulator of gene expression in mammalian tissues Nat. Chem. Biol 1 5 2005 290 297 Epub 2005 Sep 18
37. N.G. Hord, Y. Tang, and N.S. Bryan Food sources of nitrates and nitrites: the physiologic context for potential health benefits Am. J. Clin. Nutr 90 1 2009 1 10 10.3945/ajcn.2008.27131 Epub 2009 May 13
38. P.H. Lin, M. Aickin, C. Champagne, S. Craddick, F.M. Sacks, and P. McCarron Food group sources of nutrients in the dietary patterns of the DASH-Sodium trial J. Am. Diet. Assoc 103 4 2003 488 496
39. J.O.1. Lundberg, E. Weitzberg, J.M. Lundberg, and K. Alving Intragastric nitric oxide production in humans: measurements in expelled air Gut 35 11 1994 1543 1546